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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TBX2

Z-value: 1.05

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Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
TBX2
ENSG00000121068.9 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg19_v2_chr17_+_59477233_594772630.613.9e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 1.24 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr19_-_51875894 1.06 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr8_-_145060593 1.03 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr16_+_69139467 0.89 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr17_-_1553346 0.78 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr19_-_10213335 0.78 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr6_-_26027480 0.75 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr12_-_52761262 0.74 ENST00000257901.3
KRT85
keratin 85
chr2_-_191878874 0.74 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr11_-_615942 0.72 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr12_+_75874984 0.70 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr1_+_15736359 0.68 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr16_+_66461175 0.66 ENST00000536005.2
ENST00000299694.8
ENST00000561796.1
BEAN1
brain expressed, associated with NEDD4, 1
chr17_-_34122596 0.61 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chrX_-_106146547 0.59 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr5_-_78281775 0.59 ENST00000396151.3
ENST00000565165.1
ARSB
arylsulfatase B
chr5_-_119669160 0.59 ENST00000514240.1
CTC-552D5.1
CTC-552D5.1
chr9_-_96717654 0.59 ENST00000253968.6
BARX1
BARX homeobox 1
chr19_-_44174330 0.55 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr6_-_30684898 0.55 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr6_-_160166218 0.54 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr19_-_44174305 0.53 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr2_+_228736335 0.53 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr7_-_20826504 0.52 ENST00000418710.2
ENST00000361443.4
SP8
Sp8 transcription factor
chr7_-_87849340 0.52 ENST00000419179.1
ENST00000265729.2
SRI
sorcin
chr20_-_45530365 0.51 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr3_+_183967409 0.47 ENST00000324557.4
ENST00000402825.3
ECE2
endothelin converting enzyme 2
chr1_-_100643765 0.47 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr22_-_31688431 0.46 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chrX_+_56259316 0.46 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr11_-_71751715 0.45 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_74204692 0.45 ENST00000528085.1
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr11_-_115127611 0.44 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr1_-_52456352 0.43 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr1_-_153585539 0.42 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr8_+_1993173 0.42 ENST00000523438.1
MYOM2
myomesin 2
chr17_-_8027402 0.41 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr17_+_19314432 0.41 ENST00000575165.2
RNF112
ring finger protein 112
chr17_+_26662679 0.41 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr4_-_185303418 0.40 ENST00000610223.1
ENST00000608785.1
RP11-290F5.1
RP11-290F5.1
chr11_+_69455855 0.40 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr11_+_65154070 0.39 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr22_-_31688381 0.39 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_+_103058948 0.38 ENST00000262241.6
RCOR1
REST corepressor 1
chr6_+_43603552 0.37 ENST00000372171.4
MAD2L1BP
MAD2L1 binding protein
chr22_+_38597889 0.37 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr2_+_201994042 0.37 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_101702417 0.36 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chrX_+_102862834 0.36 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr11_+_120081475 0.35 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr2_+_33701286 0.35 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_+_41119794 0.35 ENST00000593463.1
LTBP4
latent transforming growth factor beta binding protein 4
chr19_-_10426663 0.34 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr3_-_120170052 0.34 ENST00000295633.3
FSTL1
follistatin-like 1
chr1_+_209878182 0.34 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr1_-_205290865 0.33 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr12_-_49351228 0.32 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr9_+_96717821 0.32 ENST00000454594.1
RP11-231K24.2
RP11-231K24.2
chr5_+_150040403 0.31 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr9_+_127023704 0.31 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr17_+_16945820 0.31 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr8_+_145218673 0.31 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr2_+_87808725 0.31 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chrX_-_46187069 0.31 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr11_-_6704513 0.31 ENST00000532203.1
ENST00000288937.6
MRPL17
mitochondrial ribosomal protein L17
chr6_-_26124138 0.30 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr6_-_31620149 0.30 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr5_+_81601166 0.30 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr16_-_66968055 0.30 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chrX_-_53461288 0.30 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr11_+_58938903 0.30 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr17_+_46184911 0.29 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
SNX11
sorting nexin 11
chr19_+_41119323 0.29 ENST00000599724.1
ENST00000597071.1
ENST00000243562.9
LTBP4
latent transforming growth factor beta binding protein 4
chr1_+_144989309 0.29 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr20_-_30539773 0.29 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr3_+_177534653 0.29 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr19_-_3500635 0.29 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr6_-_31619742 0.28 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr3_+_112930387 0.28 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr20_-_4055812 0.28 ENST00000379526.1
RP11-352D3.2
Uncharacterized protein
chr4_-_90756769 0.28 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr9_-_127177703 0.28 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chr2_-_40679186 0.28 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_+_99036996 0.27 ENST00000441580.1
ENST00000412686.1
CPSF4
cleavage and polyadenylation specific factor 4, 30kDa
chr22_+_39966758 0.27 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr1_+_155099927 0.27 ENST00000368407.3
EFNA1
ephrin-A1
chr19_-_46526304 0.27 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr17_+_25958174 0.27 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr11_+_122709200 0.26 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr11_-_133826852 0.26 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr1_-_224624730 0.26 ENST00000445239.1
WDR26
WD repeat domain 26
chr22_-_42915788 0.26 ENST00000323013.6
RRP7A
ribosomal RNA processing 7 homolog A (S. cerevisiae)
chr5_+_150639360 0.26 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr22_-_31328881 0.26 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr12_-_49351303 0.25 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr6_-_31620095 0.25 ENST00000424176.1
ENST00000456622.1
BAG6
BCL2-associated athanogene 6
chr6_+_26383318 0.25 ENST00000469230.1
ENST00000490025.1
ENST00000356709.4
ENST00000352867.2
ENST00000493275.1
ENST00000472507.1
ENST00000482536.1
ENST00000432533.2
ENST00000482842.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr19_+_55987998 0.25 ENST00000591164.1
ZNF628
zinc finger protein 628
chrX_-_53461305 0.25 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr19_-_13213662 0.25 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_46598371 0.24 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_+_20915409 0.24 ENST00000375071.3
CDA
cytidine deaminase
chr1_+_19967014 0.24 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr6_+_26383404 0.24 ENST00000416795.2
ENST00000494184.1
BTN2A2
butyrophilin, subfamily 2, member A2
chr1_+_222988464 0.24 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr3_+_137728842 0.23 ENST00000183605.5
CLDN18
claudin 18
chr10_+_47746929 0.23 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr1_+_44444865 0.23 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr12_+_93965609 0.23 ENST00000549887.1
ENST00000551556.1
SOCS2
suppressor of cytokine signaling 2
chr2_-_27498186 0.23 ENST00000447008.2
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr9_+_34329493 0.23 ENST00000379158.2
ENST00000346365.4
ENST00000379155.5
NUDT2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr11_-_66112555 0.23 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr1_+_16767167 0.22 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr18_-_48723129 0.22 ENST00000592416.1
MEX3C
mex-3 RNA binding family member C
chr3_-_126373929 0.22 ENST00000523403.1
ENST00000524230.2
TXNRD3
thioredoxin reductase 3
chr7_+_100271446 0.22 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_244227632 0.22 ENST00000598000.1
AL590483.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr12_+_57610562 0.21 ENST00000349394.5
NXPH4
neurexophilin 4
chr1_-_46598284 0.21 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_+_94551874 0.21 ENST00000551850.1
PLXNC1
plexin C1
chr3_+_112929850 0.21 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr19_-_50529193 0.21 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr4_-_177116772 0.21 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr14_+_95078714 0.21 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_+_119217422 0.21 ENST00000466984.1
TIMMDC1
translocase of inner mitochondrial membrane domain containing 1
chr15_-_52030293 0.21 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr17_-_7493390 0.21 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr2_+_219081817 0.21 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr3_+_160117062 0.21 ENST00000497311.1
SMC4
structural maintenance of chromosomes 4
chr8_+_145490549 0.20 ENST00000340695.2
SCXA
scleraxis homolog A (mouse)
chr8_+_7801144 0.20 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr6_-_31619892 0.20 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr7_-_7782204 0.20 ENST00000418534.2
AC007161.5
AC007161.5
chr8_+_1993152 0.20 ENST00000262113.4
MYOM2
myomesin 2
chr1_+_145507587 0.20 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr19_+_18492973 0.20 ENST00000595973.2
GDF15
growth differentiation factor 15
chr19_-_45737469 0.20 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr1_-_85930246 0.20 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_+_18477369 0.19 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr19_+_54641444 0.19 ENST00000221232.5
ENST00000358389.3
CNOT3
CCR4-NOT transcription complex, subunit 3
chr19_-_39523165 0.19 ENST00000509137.2
ENST00000292853.4
FBXO27
F-box protein 27
chr1_+_89829610 0.19 ENST00000370456.4
ENST00000535065.1
GBP6
guanylate binding protein family, member 6
chr17_+_76210367 0.19 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr6_-_31619697 0.19 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr20_-_1165117 0.19 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr22_-_20367797 0.19 ENST00000424787.2
GGTLC3
gamma-glutamyltransferase light chain 3
chr8_+_82192501 0.19 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr19_+_37407212 0.19 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
ZNF568
zinc finger protein 568
chr6_-_30685214 0.19 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr19_-_47353547 0.18 ENST00000601498.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr5_+_71616188 0.18 ENST00000380639.5
ENST00000543322.1
ENST00000503868.1
ENST00000510676.2
ENST00000536805.1
PTCD2
pentatricopeptide repeat domain 2
chr19_-_10420459 0.18 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr7_+_110731062 0.18 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr15_+_25200074 0.18 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr7_-_18067478 0.18 ENST00000506618.2
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr8_-_67974552 0.18 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr17_-_47925379 0.18 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr4_-_89619386 0.17 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr6_-_31651817 0.17 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr4_-_69111401 0.17 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr7_-_27135591 0.17 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr4_-_186732048 0.17 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr16_-_88717482 0.17 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr8_-_134584152 0.17 ENST00000521180.1
ENST00000517668.1
ENST00000319914.5
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr22_+_35776828 0.17 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr17_-_7232585 0.17 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr16_-_79634595 0.17 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr7_+_107220899 0.17 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr1_+_149239529 0.17 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chrY_+_20708557 0.17 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr6_-_30585009 0.17 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10
chr22_+_24823517 0.17 ENST00000496258.1
ENST00000337539.7
ADORA2A
adenosine A2a receptor
chr22_-_29949680 0.17 ENST00000397873.2
ENST00000490103.1
THOC5
THO complex 5
chr11_-_119252425 0.17 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr11_-_61735103 0.17 ENST00000529191.1
ENST00000529631.1
ENST00000530019.1
ENST00000529548.1
ENST00000273550.7
FTH1
ferritin, heavy polypeptide 1
chr19_+_50270219 0.17 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr16_+_67360856 0.17 ENST00000568804.2
LRRC36
leucine rich repeat containing 36
chr11_+_65029233 0.16 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr11_-_6633799 0.16 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr5_-_137514333 0.16 ENST00000411594.2
ENST00000430331.1
BRD8
bromodomain containing 8
chr1_-_150780757 0.16 ENST00000271651.3
CTSK
cathepsin K
chr14_-_51562037 0.16 ENST00000338969.5
TRIM9
tripartite motif containing 9
chr17_-_1029866 0.16 ENST00000570525.1
ABR
active BCR-related
chr2_-_114461655 0.16 ENST00000424612.1
AC017074.2
AC017074.2
chrX_+_55115485 0.16 ENST00000374965.1
ENST00000449097.1
PAGE2
P antigen family, member 2 (prostate associated)
chrX_-_19689106 0.16 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr10_+_60028818 0.16 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr3_+_157828152 0.16 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr17_+_44803922 0.16 ENST00000465370.1
NSF
N-ethylmaleimide-sensitive factor
chr19_-_46000251 0.16 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chrY_-_20935572 0.16 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr8_+_37963311 0.16 ENST00000428278.2
ENST00000521652.1
ASH2L
ash2 (absent, small, or homeotic)-like (Drosophila)
chr1_+_27648648 0.16 ENST00000374076.4
TMEM222
transmembrane protein 222
chr2_+_179184955 0.16 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr17_-_42402138 0.16 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39
solute carrier family 25, member 39
chr19_+_36236491 0.16 ENST00000591949.1
PSENEN
presenilin enhancer gamma secretase subunit
chr1_+_200993071 0.16 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr3_+_112930373 0.15 ENST00000498710.1
BOC
BOC cell adhesion associated, oncogene regulated
chr17_+_79031415 0.15 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr17_-_9929581 0.15 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.3 0.8 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 0.9 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 1.0 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.2 0.6 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.7 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.6 GO:0001757 somite specification(GO:0001757)
0.1 1.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 1.2 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.5 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.3 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826) regulation of cytolysis in other organism(GO:0051710)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.7 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.3 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.5 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0050787 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.6 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.2 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.3 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.4 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.6 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.3 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.5 GO:0009799 determination of left/right symmetry(GO:0007368) specification of symmetry(GO:0009799) determination of bilateral symmetry(GO:0009855)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0060323 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.5 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.6 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 3.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0099529 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha