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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TBX20

Z-value: 0.66

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Transcription factors associated with TBX20

Gene Symbol Gene ID Gene Info
TBX20
ENSG00000164532.10 T-box transcription factor 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX20hg19_v2_chr7_-_35293740_352937580.336.7e-01Click!

Activity profile of TBX20 motif

Sorted Z-values of TBX20 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57662527 1.72 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 1.11 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr19_+_56915668 0.86 ENST00000333201.9
ENST00000391778.3
ZNF583
zinc finger protein 583
chr8_+_142264664 0.56 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr2_+_64068116 0.46 ENST00000480679.1
UGP2
UDP-glucose pyrophosphorylase 2
chr15_+_76016293 0.33 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr17_-_7080227 0.31 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr11_-_14358620 0.28 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr2_-_219134343 0.27 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr2_+_64068074 0.27 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UGP2
UDP-glucose pyrophosphorylase 2
chr3_-_139396801 0.27 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr1_-_154909329 0.20 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr19_+_35810164 0.20 ENST00000598537.1
CD22
CD22 molecule
chr3_-_139396853 0.19 ENST00000406164.1
ENST00000406824.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr2_-_219134822 0.18 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr13_+_113760098 0.17 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
F7
coagulation factor VII (serum prothrombin conversion accelerator)
chr3_-_15140629 0.16 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
ZFYVE20
zinc finger, FYVE domain containing 20
chr2_+_207630081 0.15 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FASTKD2
FAST kinase domains 2
chr2_-_207629997 0.14 ENST00000454776.2
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr20_-_48782639 0.14 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr2_+_173940442 0.14 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr15_-_74421477 0.13 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr12_-_56123444 0.10 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chr5_-_89825328 0.09 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr10_+_114135952 0.08 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_-_207630033 0.08 ENST00000449792.1
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr1_+_43824669 0.07 ENST00000372462.1
CDC20
cell division cycle 20
chr5_+_133861339 0.07 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr17_-_3599492 0.07 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_44331555 0.07 ENST00000590950.1
ZNF283
zinc finger protein 283
chr1_-_17380630 0.06 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr2_+_61108650 0.05 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_+_46171464 0.05 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
GIPR
gastric inhibitory polypeptide receptor
chr5_+_135394840 0.05 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr3_+_142315225 0.05 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr19_-_4540486 0.05 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chrX_+_67913471 0.05 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr2_+_176972000 0.05 ENST00000249504.5
HOXD11
homeobox D11
chr20_+_44509857 0.04 ENST00000372523.1
ENST00000372520.1
ZSWIM1
zinc finger, SWIM-type containing 1
chr22_+_38219389 0.03 ENST00000249041.2
GALR3
galanin receptor 3
chr10_+_114135004 0.03 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_2842087 0.03 ENST00000537185.1
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr7_+_30185406 0.03 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_+_162760513 0.02 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr2_+_85360499 0.02 ENST00000282111.3
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr6_-_2842219 0.02 ENST00000380739.5
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr17_-_3599696 0.01 ENST00000225328.5
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr7_+_30185496 0.01 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_131221771 0.01 ENST00000510154.1
ENST00000507669.1
MRPL3
mitochondrial ribosomal protein L3
chr14_+_77228532 0.01 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr12_-_16762971 0.00 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation