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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TBX3

Z-value: 0.62

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
TBX3
ENSG00000135111.10 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg19_v2_chr12_-_115121962_1151219870.831.7e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_149192475 0.78 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr3_+_149191723 0.64 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr4_-_89442940 0.58 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr1_-_155959280 0.55 ENST00000495070.2
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr4_+_155484103 0.42 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_+_155484155 0.40 ENST00000509493.1
FGB
fibrinogen beta chain
chrX_-_131352152 0.40 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr14_-_107283278 0.38 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr13_-_46679144 0.38 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr4_+_178230985 0.37 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr19_-_47735918 0.37 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr3_+_124223586 0.36 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr20_-_32580924 0.35 ENST00000432859.1
RP5-1125A11.1
RP5-1125A11.1
chr11_+_327171 0.34 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr9_+_5231413 0.34 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chrX_-_57147902 0.34 ENST00000275988.5
ENST00000434397.1
ENST00000333933.3
ENST00000374912.5
SPIN2B
spindlin family, member 2B
chr14_-_92333873 0.34 ENST00000435962.2
TC2N
tandem C2 domains, nuclear
chr1_+_45274154 0.33 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr2_+_242167319 0.33 ENST00000601871.1
AC104841.2
HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr4_+_103790462 0.33 ENST00000503643.1
CISD2
CDGSH iron sulfur domain 2
chrX_-_65858865 0.32 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
EDA2R
ectodysplasin A2 receptor
chr12_+_11081828 0.29 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr1_-_151342180 0.28 ENST00000424475.1
SELENBP1
selenium binding protein 1
chr8_-_121825088 0.28 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr16_+_3062457 0.28 ENST00000445369.2
CLDN9
claudin 9
chr17_+_20483037 0.27 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr1_-_11865351 0.26 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr4_+_141264597 0.26 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr15_+_59665194 0.26 ENST00000560394.1
FAM81A
family with sequence similarity 81, member A
chr12_-_88535747 0.26 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr6_+_26087646 0.25 ENST00000309234.6
HFE
hemochromatosis
chr7_+_106415457 0.23 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr6_-_52628271 0.23 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr12_-_88535842 0.23 ENST00000550962.1
ENST00000552810.1
CEP290
centrosomal protein 290kDa
chr19_+_1077393 0.22 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr12_+_4430371 0.22 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr7_+_102389434 0.22 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr6_+_126661253 0.21 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr12_-_79849240 0.21 ENST00000550268.1
RP1-78O14.1
RP1-78O14.1
chr2_+_162101247 0.21 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr20_+_55108302 0.21 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr13_+_73356197 0.21 ENST00000326291.6
PIBF1
progesterone immunomodulatory binding factor 1
chr12_+_133757995 0.21 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr6_-_52668605 0.21 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr8_+_79578282 0.21 ENST00000263849.4
ZC2HC1A
zinc finger, C2HC-type containing 1A
chr1_-_241799232 0.21 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr15_+_30918879 0.21 ENST00000428041.2
ARHGAP11B
Rho GTPase activating protein 11B
chr20_-_4229721 0.21 ENST00000379453.4
ADRA1D
adrenoceptor alpha 1D
chr4_+_15704573 0.20 ENST00000265016.4
BST1
bone marrow stromal cell antigen 1
chr3_+_133293278 0.20 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chr12_+_133758115 0.20 ENST00000541009.2
ENST00000592241.1
ZNF268
zinc finger protein 268
chr3_+_189349162 0.19 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr10_+_90750378 0.19 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr10_-_14996321 0.18 ENST00000378289.4
DCLRE1C
DNA cross-link repair 1C
chr11_-_27722021 0.18 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr1_-_242612779 0.18 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr2_+_24150180 0.17 ENST00000404924.1
UBXN2A
UBX domain protein 2A
chr2_-_26569611 0.16 ENST00000541401.1
ENST00000433584.1
ENST00000333478.6
GPR113
G protein-coupled receptor 113
chr4_-_46911223 0.16 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr3_-_121264848 0.16 ENST00000264233.5
POLQ
polymerase (DNA directed), theta
chr19_-_33360647 0.16 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr15_-_50411412 0.16 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr15_+_77712993 0.16 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr11_-_1619524 0.16 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr2_-_209118974 0.14 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr12_+_50478977 0.14 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_-_3504587 0.14 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr12_+_16500599 0.14 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr10_+_94608245 0.13 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr11_+_71259466 0.13 ENST00000528743.2
KRTAP5-9
keratin associated protein 5-9
chr19_+_58281014 0.13 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
ZNF586
zinc finger protein 586
chr11_+_19138670 0.13 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr18_+_5238055 0.12 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr20_+_17949544 0.12 ENST00000377710.5
MGME1
mitochondrial genome maintenance exonuclease 1
chr18_-_25616519 0.12 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr9_-_95087604 0.12 ENST00000542613.1
ENST00000542053.1
ENST00000358855.4
ENST00000545558.1
ENST00000432670.2
ENST00000433029.2
ENST00000411621.2
NOL8
nucleolar protein 8
chrX_+_46306714 0.12 ENST00000298190.6
ENST00000377919.2
ENST00000476762.1
ENST00000478600.1
KRBOX4
KRAB box domain containing 4
chr20_+_34679725 0.11 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_51810778 0.11 ENST00000413473.2
ENST00000401051.3
ENST00000527205.1
TTC39A
tetratricopeptide repeat domain 39A
chr12_+_88536067 0.11 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3
transmembrane and tetratricopeptide repeat containing 3
chr11_-_73689037 0.11 ENST00000544615.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr3_-_46068969 0.11 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr4_+_187148556 0.11 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr21_-_43346790 0.11 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr11_-_18656028 0.10 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr9_-_39288092 0.10 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr6_-_35888905 0.10 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr10_+_32856764 0.10 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr12_+_12223867 0.10 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr15_+_31196080 0.10 ENST00000561607.1
ENST00000565466.1
FAN1
FANCD2/FANCI-associated nuclease 1
chr5_-_40755987 0.10 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr12_+_16500571 0.10 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr1_-_47131521 0.10 ENST00000542495.1
ENST00000532925.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr20_+_17949724 0.10 ENST00000377704.4
MGME1
mitochondrial genome maintenance exonuclease 1
chr11_+_34643600 0.10 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr10_-_1071796 0.10 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr12_+_57849048 0.10 ENST00000266646.2
INHBE
inhibin, beta E
chr5_+_140753444 0.09 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr9_-_100954910 0.09 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr12_+_124155652 0.09 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr4_-_83765613 0.09 ENST00000503937.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr11_+_130542851 0.09 ENST00000317019.2
C11orf44
chromosome 11 open reading frame 44
chr2_-_165698662 0.09 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr15_-_80695917 0.09 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr5_-_137610254 0.09 ENST00000378362.3
GFRA3
GDNF family receptor alpha 3
chr5_+_35617940 0.09 ENST00000282469.6
ENST00000509059.1
ENST00000356031.3
ENST00000510777.1
SPEF2
sperm flagellar 2
chr12_+_48876275 0.09 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr2_-_55459485 0.09 ENST00000451916.1
CLHC1
clathrin heavy chain linker domain containing 1
chr11_+_65190245 0.09 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_7506837 0.09 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr12_-_56121580 0.09 ENST00000550776.1
CD63
CD63 molecule
chr19_+_53868940 0.09 ENST00000474037.1
ENST00000491101.1
ENST00000467003.1
ENST00000475179.1
ENST00000593918.1
ZNF525
zinc finger protein 525
chr1_+_171810606 0.09 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr6_+_52285046 0.09 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr19_-_47291843 0.08 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_+_7506713 0.08 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr17_-_28661065 0.08 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr1_-_101491319 0.08 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr6_-_55443975 0.08 ENST00000308161.4
ENST00000398661.2
ENST00000274901.4
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr3_+_52454971 0.08 ENST00000465863.1
PHF7
PHD finger protein 7
chr1_+_26869597 0.08 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr22_-_38480100 0.08 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr15_+_59664884 0.08 ENST00000558348.1
FAM81A
family with sequence similarity 81, member A
chr19_+_496454 0.08 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr17_+_39411636 0.07 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr16_+_83932684 0.07 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr2_-_24149977 0.07 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr14_+_90422867 0.07 ENST00000553989.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr14_-_74416829 0.07 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr17_-_7017559 0.07 ENST00000446679.2
ASGR2
asialoglycoprotein receptor 2
chr7_+_95401877 0.07 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr2_+_178257372 0.07 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr16_+_66914264 0.07 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_+_187896331 0.07 ENST00000392468.2
AC022498.1
Uncharacterized protein
chr9_+_71394945 0.07 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr12_-_56121612 0.07 ENST00000546939.1
CD63
CD63 molecule
chr15_+_31196053 0.07 ENST00000561594.1
ENST00000362065.4
FAN1
FANCD2/FANCI-associated nuclease 1
chr22_+_24891210 0.07 ENST00000382760.2
UPB1
ureidopropionase, beta
chr13_-_73356234 0.06 ENST00000545453.1
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr16_-_67360662 0.06 ENST00000304372.5
KCTD19
potassium channel tetramerization domain containing 19
chr6_-_33771757 0.06 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
MLN
motilin
chr16_+_50099852 0.06 ENST00000299192.7
ENST00000285767.4
HEATR3
HEAT repeat containing 3
chr10_-_44144152 0.06 ENST00000395797.1
ZNF32
zinc finger protein 32
chrX_+_149887090 0.06 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr4_-_85654615 0.06 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr20_-_1472029 0.06 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr19_+_33865218 0.06 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr16_+_84801852 0.06 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr14_+_77924204 0.06 ENST00000555133.1
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr4_+_156824840 0.06 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr11_+_20044600 0.06 ENST00000311043.8
NAV2
neuron navigator 2
chr19_+_42724423 0.06 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr1_+_201755452 0.06 ENST00000438083.1
NAV1
neuron navigator 1
chr5_-_135290651 0.06 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr5_+_139739772 0.06 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr18_+_48918368 0.05 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr20_+_30865429 0.05 ENST00000375712.3
KIF3B
kinesin family member 3B
chr7_+_99971068 0.05 ENST00000198536.2
ENST00000453419.1
PILRA
paired immunoglobin-like type 2 receptor alpha
chr10_-_13523073 0.05 ENST00000440282.1
BEND7
BEN domain containing 7
chr5_+_32788945 0.05 ENST00000326958.1
AC026703.1
AC026703.1
chr14_+_21785693 0.05 ENST00000382933.4
ENST00000557351.1
RPGRIP1
retinitis pigmentosa GTPase regulator interacting protein 1
chrX_-_65859096 0.05 ENST00000456230.2
EDA2R
ectodysplasin A2 receptor
chr11_+_18433840 0.05 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr3_-_48659193 0.05 ENST00000330862.3
TMEM89
transmembrane protein 89
chr7_+_117119187 0.05 ENST00000446805.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr4_-_108641608 0.05 ENST00000265174.4
PAPSS1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr4_-_190948409 0.05 ENST00000504750.1
ENST00000378763.1
FRG2
FSHD region gene 2
chr7_+_99971129 0.05 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr16_+_58283814 0.05 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr17_+_43861680 0.05 ENST00000314537.5
CRHR1
corticotropin releasing hormone receptor 1
chr9_+_125281420 0.05 ENST00000340750.1
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr12_-_56120838 0.04 ENST00000548160.1
CD63
CD63 molecule
chr22_-_36031181 0.04 ENST00000594060.1
AL049747.1
AL049747.1
chr14_+_96505659 0.04 ENST00000555004.1
C14orf132
chromosome 14 open reading frame 132
chr1_+_162602244 0.04 ENST00000367922.3
ENST00000367921.3
DDR2
discoidin domain receptor tyrosine kinase 2
chr19_+_39936207 0.04 ENST00000594729.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr11_+_71238313 0.04 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr16_+_72088376 0.04 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr1_+_32608566 0.04 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr19_-_10491234 0.04 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr1_-_212208842 0.04 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7
integrator complex subunit 7
chr2_-_133429091 0.04 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr7_+_6713376 0.04 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr6_+_52285131 0.04 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr1_+_36396313 0.04 ENST00000324350.5
AGO3
argonaute RISC catalytic component 3
chr1_+_156551157 0.04 ENST00000368237.3
TTC24
tetratricopeptide repeat domain 24
chr4_-_83812402 0.04 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_+_96331830 0.04 ENST00000425887.2
AC008268.1
AC008268.1
chr3_-_172019686 0.04 ENST00000596321.1
AC092964.2
Uncharacterized protein
chr5_+_40841410 0.03 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr15_+_77713299 0.03 ENST00000559099.1
HMG20A
high mobility group 20A
chr2_+_234637754 0.03 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_52322019 0.03 ENST00000463624.1
WDR82
WD repeat domain 82
chr5_+_175740083 0.03 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr7_-_19748640 0.03 ENST00000222567.5
TWISTNB
TWIST neighbor
chr17_+_26800756 0.03 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_+_220267429 0.03 ENST00000366922.1
ENST00000302637.5
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
chr5_+_145826867 0.03 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_-_231560790 0.03 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr11_-_62607036 0.03 ENST00000311713.7
ENST00000278856.4
WDR74
WD repeat domain 74

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 1.4 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0016939 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.0 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins