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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TBX5

Z-value: 1.17

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Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
TBX5
ENSG00000089225.15 T-box transcription factor 5

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39786962 2.20 ENST00000333625.2
IFNL1
interferon, lambda 1
chr14_-_37051798 1.52 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr17_+_68165657 1.35 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr16_-_11350036 1.27 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr8_-_145060593 1.15 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr2_-_191878874 1.01 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr11_+_117947724 0.99 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr2_-_42160486 0.95 ENST00000427054.1
AC104654.2
AC104654.2
chr5_-_134914673 0.89 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr15_+_89182156 0.85 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr3_-_182880541 0.83 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr15_+_89182178 0.80 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_57023406 0.76 ENST00000262510.6
ENST00000308149.7
ENST00000436936.1
NLRC5
NLR family, CARD domain containing 5
chr1_+_15736359 0.74 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr20_-_4055812 0.72 ENST00000379526.1
RP11-352D3.2
Uncharacterized protein
chr22_-_20231207 0.72 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr15_+_89181974 0.62 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_83073952 0.60 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr19_-_10213335 0.60 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr6_-_26027480 0.59 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr22_+_38597889 0.58 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr11_-_115127611 0.57 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr17_+_74372662 0.56 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr3_-_120170052 0.56 ENST00000295633.3
FSTL1
follistatin-like 1
chr1_+_8378140 0.51 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr2_+_101591314 0.50 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr2_+_5832799 0.50 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr22_-_51016433 0.48 ENST00000405237.3
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr11_-_45928830 0.48 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chr19_+_18723660 0.46 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr8_-_123793048 0.44 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr22_-_51016846 0.44 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr12_-_116714564 0.43 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr6_-_19804973 0.43 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr8_+_32405728 0.42 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr5_-_74348371 0.42 ENST00000503568.1
RP11-229C3.2
RP11-229C3.2
chr9_-_96717654 0.42 ENST00000253968.6
BARX1
BARX homeobox 1
chr17_-_79817091 0.42 ENST00000570907.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_-_12677714 0.41 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr22_+_31488433 0.40 ENST00000455608.1
SMTN
smoothelin
chr11_-_74660065 0.39 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr1_-_153521714 0.38 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr16_-_67190152 0.37 ENST00000486556.1
TRADD
TNFRSF1A-associated via death domain
chr8_+_32405785 0.37 ENST00000287842.3
NRG1
neuregulin 1
chr19_+_41107249 0.36 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr5_-_180229791 0.36 ENST00000504671.1
ENST00000507384.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_-_134095335 0.35 ENST00000534227.1
ENST00000532445.1
NCAPD3
non-SMC condensin II complex, subunit D3
chr3_+_183899770 0.35 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_+_112563303 0.35 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr17_-_73937028 0.34 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr4_-_140222358 0.34 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr12_+_19358192 0.34 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr11_-_125932685 0.34 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr18_+_33877654 0.33 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr17_-_26220366 0.33 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr17_+_77020146 0.33 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_40119801 0.33 ENST00000585452.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr11_+_58390132 0.33 ENST00000361987.4
CNTF
ciliary neurotrophic factor
chr6_+_122931366 0.32 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr15_+_41099254 0.32 ENST00000570108.1
ENST00000564258.1
ENST00000355341.4
ENST00000336455.5
ZFYVE19
zinc finger, FYVE domain containing 19
chr3_-_48632593 0.32 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr12_-_49351303 0.31 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr17_+_77020325 0.31 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_+_77020224 0.31 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_-_72968837 0.31 ENST00000581676.1
HID1
HID1 domain containing
chr22_+_38609538 0.31 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr1_+_228395755 0.31 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr4_+_81118647 0.31 ENST00000415738.2
PRDM8
PR domain containing 8
chr20_+_45523227 0.30 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr17_+_57970469 0.30 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr17_-_15469590 0.30 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr11_+_46402297 0.30 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_19689106 0.29 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr15_+_91416092 0.29 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr2_-_61697862 0.29 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_+_112563335 0.29 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr16_+_57139933 0.29 ENST00000566259.1
CPNE2
copine II
chr11_+_120081475 0.29 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr10_+_135340859 0.29 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr19_+_1000418 0.28 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr17_+_79859985 0.28 ENST00000333383.7
NPB
neuropeptide B
chrX_-_83757399 0.27 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr20_-_45530365 0.27 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr10_-_125853200 0.26 ENST00000421115.1
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr19_+_54385439 0.26 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
PRKCG
protein kinase C, gamma
chr1_-_149982624 0.26 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr19_+_10397648 0.26 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr22_-_51017084 0.26 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr17_+_77021702 0.26 ENST00000392445.2
ENST00000354124.3
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr7_+_96634850 0.26 ENST00000518156.2
DLX6
distal-less homeobox 6
chr21_+_30503282 0.26 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr4_+_183065793 0.26 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr9_+_96717821 0.25 ENST00000454594.1
RP11-231K24.2
RP11-231K24.2
chr3_+_184016986 0.25 ENST00000417952.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr3_-_52719912 0.25 ENST00000420148.1
PBRM1
polybromo 1
chr22_-_30722912 0.25 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr19_+_50380917 0.25 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr3_-_48594248 0.24 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr20_-_30310336 0.24 ENST00000434194.1
ENST00000376062.2
BCL2L1
BCL2-like 1
chr15_+_41913690 0.24 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chrX_+_102862834 0.24 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr6_-_30043539 0.23 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr2_+_171673417 0.23 ENST00000344257.5
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr12_+_57854274 0.23 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr17_-_7297833 0.23 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_-_34535297 0.23 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr1_+_168250194 0.23 ENST00000367821.3
TBX19
T-box 19
chr6_-_31620095 0.23 ENST00000424176.1
ENST00000456622.1
BAG6
BCL2-associated athanogene 6
chr2_+_234668894 0.23 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr16_+_30007524 0.23 ENST00000567254.1
ENST00000567705.1
INO80E
INO80 complex subunit E
chr16_+_20911174 0.22 ENST00000568663.1
LYRM1
LYR motif containing 1
chr15_-_43863695 0.22 ENST00000439195.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr2_+_171673072 0.22 ENST00000358196.3
ENST00000375272.1
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr19_-_8579030 0.22 ENST00000255616.8
ENST00000393927.4
ZNF414
zinc finger protein 414
chr1_-_47655686 0.22 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr1_-_153917700 0.22 ENST00000368646.2
DENND4B
DENN/MADD domain containing 4B
chr17_-_46507567 0.22 ENST00000584924.1
SKAP1
src kinase associated phosphoprotein 1
chr12_-_49351228 0.22 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr6_-_31619742 0.21 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr19_+_50380682 0.21 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr1_-_33502528 0.21 ENST00000354858.6
AK2
adenylate kinase 2
chr7_-_27135591 0.21 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr1_-_205290865 0.21 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chrX_-_80377162 0.21 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chrX_+_56259316 0.21 ENST00000468660.1
KLF8
Kruppel-like factor 8
chr1_-_44482979 0.21 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr16_-_3086927 0.20 ENST00000572449.1
CCDC64B
coiled-coil domain containing 64B
chr12_+_8234807 0.20 ENST00000339754.5
NECAP1
NECAP endocytosis associated 1
chr19_+_55987998 0.20 ENST00000591164.1
ZNF628
zinc finger protein 628
chr22_-_30722866 0.20 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr1_+_26737253 0.20 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr16_+_2546033 0.20 ENST00000564543.1
ENST00000434757.2
RP11-20I23.1
TBC1D24
Uncharacterized protein
TBC1 domain family, member 24
chr15_-_74043816 0.20 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr11_-_119252425 0.20 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr6_-_31619697 0.20 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr9_-_16276311 0.20 ENST00000380685.1
C9orf92
chromosome 9 open reading frame 92
chr7_-_105319536 0.20 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr1_+_41447609 0.20 ENST00000543104.1
CTPS1
CTP synthase 1
chr6_-_19804877 0.20 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr12_-_53228079 0.20 ENST00000330553.5
KRT79
keratin 79
chr17_+_16945820 0.20 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr2_-_218766698 0.19 ENST00000439083.1
TNS1
tensin 1
chr19_+_10397621 0.19 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chrX_+_33744503 0.19 ENST00000439992.1
RP11-305F18.1
RP11-305F18.1
chr16_+_2588012 0.19 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr11_-_72385437 0.19 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr19_-_41942344 0.19 ENST00000594660.1
ATP5SL
ATP5S-like
chrX_-_148713365 0.19 ENST00000511776.1
ENST00000507237.1
TMEM185A
transmembrane protein 185A
chr11_+_117947782 0.19 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
TMPRSS4
transmembrane protease, serine 4
chr1_-_33502441 0.19 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr19_-_11456935 0.19 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr18_+_3449695 0.19 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr1_+_153963227 0.18 ENST00000368567.4
ENST00000392558.4
RPS27
ribosomal protein S27
chr5_+_125758813 0.18 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr22_-_30662828 0.18 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr11_-_72145426 0.18 ENST00000535990.1
ENST00000437826.2
ENST00000340729.5
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr16_+_57844549 0.18 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chr1_+_26737292 0.18 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr2_+_153191706 0.18 ENST00000288670.9
FMNL2
formin-like 2
chr2_+_201994208 0.18 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_107602030 0.18 ENST00000494231.1
LINC00636
long intergenic non-protein coding RNA 636
chr2_-_200322723 0.18 ENST00000417098.1
SATB2
SATB homeobox 2
chr5_+_125758865 0.18 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr2_+_210636697 0.18 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr1_+_101702417 0.18 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr9_-_79307096 0.17 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr11_-_34535332 0.17 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr18_+_54318893 0.17 ENST00000593058.1
WDR7
WD repeat domain 7
chr11_-_72145641 0.17 ENST00000538039.1
ENST00000445069.2
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr11_+_114310164 0.17 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr19_-_11456872 0.17 ENST00000586218.1
TMEM205
transmembrane protein 205
chr11_+_114310102 0.17 ENST00000265881.5
REXO2
RNA exonuclease 2
chr6_-_31620149 0.16 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr1_-_151119087 0.16 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr5_-_142784888 0.16 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_-_31147020 0.16 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr8_+_81397876 0.16 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr1_+_202995611 0.15 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr17_+_34431212 0.15 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr7_-_130080681 0.15 ENST00000469826.1
CEP41
centrosomal protein 41kDa
chr11_-_119252359 0.15 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr19_-_11456905 0.15 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr22_-_46373004 0.15 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr6_-_31619892 0.15 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr17_-_46703826 0.15 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr12_-_62586543 0.15 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chrX_+_35937843 0.15 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr6_+_34204642 0.15 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr16_-_4465886 0.15 ENST00000539968.1
CORO7
coronin 7
chr6_+_43445261 0.14 ENST00000372444.2
ENST00000372445.5
ENST00000436109.2
ENST00000372454.2
ENST00000442878.2
ENST00000259751.1
ENST00000372452.1
ENST00000372449.1
TJAP1
tight junction associated protein 1 (peripheral)
chr2_+_149402553 0.14 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr13_-_79177673 0.14 ENST00000377208.5
POU4F1
POU class 4 homeobox 1
chr1_+_13910194 0.14 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr8_-_95907423 0.14 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr12_-_52887034 0.14 ENST00000330722.6
KRT6A
keratin 6A
chr22_-_31885514 0.14 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr4_-_186456766 0.14 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr16_+_30662360 0.14 ENST00000542965.2
PRR14
proline rich 14
chr19_-_50380536 0.14 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr11_-_72145669 0.14 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.5 2.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.0 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.2 1.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0046364 hexose biosynthetic process(GO:0019319) monosaccharide biosynthetic process(GO:0046364)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.1 1.0 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.4 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 0.4 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.1 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.2 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.7 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.6 GO:0007567 parturition(GO:0007567)
0.0 0.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.1 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.0 0.2 GO:0007507 heart development(GO:0007507)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0061053 somite development(GO:0061053)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.0 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.0 GO:0071288 carbon dioxide transmembrane transport(GO:0035378) positive regulation of saliva secretion(GO:0046878) cellular response to mercury ion(GO:0071288)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 0.7 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 1.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.7 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 1.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151) sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 2.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling