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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 1.45

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.188.2e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_38177575 2.21 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr20_-_46415297 1.56 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr4_-_89442940 1.48 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr17_-_7081435 1.18 ENST00000380920.4
ASGR1
asialoglycoprotein receptor 1
chr9_-_123812542 1.15 ENST00000223642.1
C5
complement component 5
chr4_+_106816592 1.05 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT
nephronectin
chr12_+_69201923 1.04 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_+_212738676 1.02 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr3_-_182833863 1.00 ENST00000492597.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr8_-_71519889 0.96 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr12_-_105352047 0.94 ENST00000432951.1
ENST00000415674.1
ENST00000424946.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr10_-_15413035 0.92 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr14_-_53258180 0.91 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr20_-_46415341 0.87 ENST00000484875.1
ENST00000361612.4
SULF2
sulfatase 2
chr3_+_167453493 0.86 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_-_34043310 0.83 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr6_-_39197226 0.77 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chrX_-_150067069 0.76 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr4_+_37892682 0.74 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr5_-_142784003 0.74 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_33701684 0.72 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_139055055 0.72 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr12_-_68845417 0.70 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr17_+_6347761 0.70 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
FAM64A
family with sequence similarity 64, member A
chr8_-_95961578 0.70 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr12_+_56473628 0.67 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr17_+_39421591 0.66 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr11_-_75921780 0.66 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chrX_+_69509927 0.65 ENST00000374403.3
KIF4A
kinesin family member 4A
chr5_+_68462837 0.65 ENST00000256442.5
CCNB1
cyclin B1
chr13_+_41635617 0.65 ENST00000542082.1
WBP4
WW domain binding protein 4
chr3_+_167453026 0.64 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr21_+_17791648 0.60 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_-_106960285 0.60 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr17_+_71229346 0.58 ENST00000535032.2
ENST00000582793.1
C17orf80
chromosome 17 open reading frame 80
chr5_+_71475449 0.57 ENST00000504492.1
MAP1B
microtubule-associated protein 1B
chr1_-_114429997 0.55 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr1_-_21113105 0.55 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3
heterochromatin protein 1, binding protein 3
chr2_+_171627597 0.55 ENST00000429172.1
ENST00000426475.1
AC007405.6
AC007405.6
chr20_+_34802295 0.54 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_44001172 0.53 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr5_+_68462944 0.53 ENST00000506572.1
CCNB1
cyclin B1
chr17_+_34848049 0.52 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr11_+_47270475 0.52 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr10_+_94594351 0.52 ENST00000371552.4
EXOC6
exocyst complex component 6
chr1_+_203256898 0.52 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr2_+_61244697 0.52 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
PEX13
peroxisomal biogenesis factor 13
chr9_-_33447584 0.52 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr14_-_23288930 0.51 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_+_72975524 0.51 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr10_+_104614008 0.50 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr11_+_72975578 0.49 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr4_-_153303658 0.49 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_139055021 0.49 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr1_+_28261621 0.49 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr2_-_228028829 0.47 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr5_+_95066823 0.47 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr1_-_63782888 0.46 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr11_+_827553 0.46 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr10_+_98592009 0.46 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr4_+_95972822 0.45 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr4_-_46911223 0.45 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr2_-_191115229 0.45 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr6_-_72130472 0.44 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr6_-_41673552 0.44 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr5_+_68463043 0.44 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr17_-_62499334 0.43 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr2_-_55276320 0.43 ENST00000357376.3
RTN4
reticulon 4
chrX_-_150067173 0.43 ENST00000370377.3
ENST00000320893.6
CD99L2
CD99 molecule-like 2
chr17_-_63052929 0.42 ENST00000439174.2
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr9_+_2029019 0.42 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_102721023 0.41 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr12_-_6960407 0.41 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr11_+_72975559 0.41 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_+_179065474 0.41 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr9_-_3469181 0.40 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr1_-_116926718 0.39 ENST00000598661.1
AL136376.1
Uncharacterized protein
chrX_+_15756382 0.39 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr5_-_42811986 0.39 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr16_+_29832634 0.39 ENST00000565164.1
ENST00000570234.1
MVP
major vault protein
chr19_+_16187085 0.39 ENST00000300933.4
TPM4
tropomyosin 4
chr6_+_143772060 0.39 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr11_+_47270436 0.38 ENST00000395397.3
ENST00000405576.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr6_-_33160231 0.38 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr6_+_10528560 0.38 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr17_+_6347729 0.38 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr11_-_82997371 0.38 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr1_+_28261533 0.37 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_243326612 0.37 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr11_-_14913765 0.37 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr13_+_51483814 0.37 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chr5_-_59995921 0.37 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B
DEP domain containing 1B
chr18_-_55470320 0.37 ENST00000536015.1
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr7_-_104909435 0.35 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr6_-_135375921 0.35 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1L
HBS1-like (S. cerevisiae)
chr11_-_14913190 0.35 ENST00000532378.1
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr2_-_234763105 0.35 ENST00000454020.1
HJURP
Holliday junction recognition protein
chr4_-_89152474 0.34 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr17_-_46671323 0.34 ENST00000239151.5
HOXB5
homeobox B5
chr14_+_69658194 0.34 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
EXD2
exonuclease 3'-5' domain containing 2
chr6_-_135375986 0.33 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L
HBS1-like (S. cerevisiae)
chr17_-_15165825 0.32 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr6_-_128841503 0.32 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr11_+_125496619 0.32 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr20_-_52210368 0.32 ENST00000371471.2
ZNF217
zinc finger protein 217
chr16_+_83932684 0.32 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr19_+_57999101 0.32 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
ZNF419
zinc finger protein 419
chr17_-_46657473 0.32 ENST00000332503.5
HOXB4
homeobox B4
chr2_-_17981462 0.32 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr12_-_105352080 0.32 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr3_-_184971853 0.32 ENST00000231887.3
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr7_-_44105158 0.32 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr8_-_55014415 0.31 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr17_-_43025005 0.31 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
KIF18B
kinesin family member 18B
chr1_-_94374946 0.31 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr20_+_30327063 0.31 ENST00000300403.6
ENST00000340513.4
TPX2
TPX2, microtubule-associated
chr3_-_176915215 0.30 ENST00000457928.2
ENST00000422442.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr8_-_82633476 0.30 ENST00000518419.1
ENST00000517588.1
ENST00000521895.1
ENST00000520076.1
ENST00000519523.1
ENST00000522520.1
ENST00000521287.1
ENST00000523096.1
ENST00000220669.5
ENST00000517450.1
ZFAND1
zinc finger, AN1-type domain 1
chr10_+_60094735 0.29 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr1_+_78354175 0.29 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr11_-_18656028 0.29 ENST00000336349.5
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr20_-_23030296 0.29 ENST00000377103.2
THBD
thrombomodulin
chr7_-_11871815 0.28 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr1_-_45253377 0.28 ENST00000372207.3
BEST4
bestrophin 4
chr3_+_101498269 0.28 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_+_101498074 0.28 ENST00000273347.5
ENST00000474165.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr11_-_31531121 0.28 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chrX_-_16887963 0.28 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr2_-_3595547 0.28 ENST00000438485.1
RP13-512J5.1
Uncharacterized protein
chrX_-_78622805 0.28 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr8_+_33342268 0.27 ENST00000360128.6
MAK16
MAK16 homolog (S. cerevisiae)
chr15_-_42749711 0.27 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr8_-_117886955 0.27 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr17_+_71228740 0.27 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr22_+_31460091 0.27 ENST00000432777.1
ENST00000422839.1
SMTN
smoothelin
chr17_+_16593539 0.27 ENST00000340621.5
ENST00000399273.1
ENST00000443444.2
ENST00000360524.8
ENST00000456009.1
CCDC144A
coiled-coil domain containing 144A
chr12_+_9142131 0.26 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_-_10920838 0.26 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr21_+_17791838 0.26 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr14_-_50154921 0.26 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr12_+_16500599 0.26 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr17_-_19265855 0.26 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr18_-_47376197 0.26 ENST00000592688.1
MYO5B
myosin VB
chr2_+_219537015 0.25 ENST00000440309.1
ENST00000424080.1
STK36
serine/threonine kinase 36
chr11_+_125496124 0.25 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr2_+_56411131 0.25 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr11_+_31531291 0.24 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr11_-_82997420 0.24 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr1_+_46859933 0.24 ENST00000243167.8
FAAH
fatty acid amide hydrolase
chr17_-_15165854 0.24 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr1_-_206785789 0.24 ENST00000437518.1
ENST00000367114.3
EIF2D
eukaryotic translation initiation factor 2D
chr6_+_150070831 0.24 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_+_29421987 0.24 ENST00000431387.4
NF1
neurofibromin 1
chr6_-_31697563 0.24 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr12_+_14572070 0.23 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_150669500 0.23 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr3_+_141106643 0.23 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr10_-_51130715 0.23 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr9_-_100954910 0.23 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr22_+_21369316 0.23 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr1_+_14075865 0.23 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr10_-_52645416 0.23 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr2_-_214148921 0.22 ENST00000360083.3
AC079610.2
AC079610.2
chr10_-_46641003 0.22 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
PTPN20A
protein tyrosine phosphatase, non-receptor type 20A
chr12_-_58329819 0.22 ENST00000551421.1
RP11-620J15.3
RP11-620J15.3
chr2_+_149402009 0.22 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr12_-_50677255 0.22 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr1_+_51701924 0.22 ENST00000242719.3
RNF11
ring finger protein 11
chr14_+_104710541 0.22 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr19_-_4535233 0.21 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr15_-_76304731 0.21 ENST00000394907.3
NRG4
neuregulin 4
chr8_-_99837856 0.21 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr8_-_92053212 0.21 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr3_-_156840776 0.21 ENST00000471357.1
LINC00880
long intergenic non-protein coding RNA 880
chr11_+_1855645 0.21 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr7_-_37024665 0.21 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr19_+_46801639 0.21 ENST00000244303.6
ENST00000339613.2
ENST00000533145.1
ENST00000472815.1
HIF3A
hypoxia inducible factor 3, alpha subunit
chr11_+_74862100 0.21 ENST00000532236.1
ENST00000531756.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr6_-_116833500 0.20 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr11_+_7597639 0.20 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_-_46655538 0.20 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr6_-_13711773 0.20 ENST00000011619.3
RANBP9
RAN binding protein 9
chrX_+_48432892 0.19 ENST00000376759.3
ENST00000430348.2
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr1_-_206785898 0.19 ENST00000271764.2
EIF2D
eukaryotic translation initiation factor 2D
chr6_+_30852130 0.19 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_-_128400788 0.19 ENST00000409286.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr5_+_148960931 0.19 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr15_+_63796779 0.19 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr8_+_38089198 0.19 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2
DDHD domain containing 2
chrX_-_107334790 0.19 ENST00000217958.3
PSMD10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_+_87563557 0.19 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr2_+_219536749 0.18 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
STK36
serine/threonine kinase 36
chr2_+_63816295 0.18 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr4_+_106816644 0.18 ENST00000506666.1
ENST00000503451.1
NPNT
nephronectin
chr2_+_113321939 0.18 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr2_-_152590946 0.18 ENST00000172853.10
NEB
nebulin
chr5_-_158757895 0.18 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr1_-_23857698 0.18 ENST00000361729.2
E2F2
E2F transcription factor 2
chr1_-_150849208 0.18 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr16_-_31100284 0.18 ENST00000280606.6
PRSS53
protease, serine, 53

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 1.6 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.4 1.2 GO:0097195 pilomotor reflex(GO:0097195)
0.3 1.0 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.7 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.2 0.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.7 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.7 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.9 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.5 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.4 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.5 GO:0070295 renal water absorption(GO:0070295)
0.1 0.8 GO:0071638 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.2 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.6 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.1 GO:0090092 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393) SMAD protein signal transduction(GO:0060395) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090092) positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0090100)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 1.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0034091 regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.6 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.1 GO:1901804 termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 1.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.6 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.5 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.2 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.2 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.0 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 2.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 1.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.7 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 1.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.4 GO:0045029 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 1.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.9 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.4 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.3 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression