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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for THRA_RXRB

Z-value: 2.20

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Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
THRA
ENSG00000126351.8 thyroid hormone receptor alpha
RXRB
ENSG00000204231.6 retinoid X receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
THRAhg19_v2_chr17_+_38219063_382191540.752.5e-01Click!
RXRBhg19_v2_chr6_-_33168391_33168465-0.059.5e-01Click!

Activity profile of THRA_RXRB motif

Sorted Z-values of THRA_RXRB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_102513950 2.41 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr1_+_229440129 1.98 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr9_-_33402506 1.94 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr5_+_162887556 1.89 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR
hyaluronan-mediated motility receptor (RHAMM)
chr19_+_49467232 1.76 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
CTD-2639E6.9
chr1_-_150693318 1.68 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chrX_-_30327495 1.51 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr11_-_17565854 1.46 ENST00000005226.7
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr17_-_7082861 1.44 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr6_+_35773070 1.42 ENST00000373853.1
ENST00000360215.1
LHFPL5
lipoma HMGIC fusion partner-like 5
chr11_-_65837090 1.39 ENST00000529036.1
RP11-1167A19.2
Uncharacterized protein
chr1_-_12679171 1.35 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr1_-_150693305 1.28 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr5_-_162887054 1.25 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr19_-_49565254 1.18 ENST00000593537.1
NTF4
neurotrophin 4
chr5_+_149865377 1.18 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr14_-_58893832 1.17 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr12_+_56477093 1.16 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_+_41221794 1.11 ENST00000547849.1
CNTN1
contactin 1
chr8_+_86999516 1.07 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr16_+_28874345 1.01 ENST00000566209.1
SH2B1
SH2B adaptor protein 1
chr17_-_27503770 1.01 ENST00000533112.1
MYO18A
myosin XVIIIA
chr1_-_242612779 0.99 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr19_+_1248547 0.96 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr12_+_57854274 0.96 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr22_-_20138302 0.93 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr10_+_99332198 0.92 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr3_+_10068095 0.91 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr22_-_37880543 0.87 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_15374659 0.87 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr16_+_67700673 0.85 ENST00000403458.4
ENST00000602365.1
C16orf86
chromosome 16 open reading frame 86
chr17_+_37894570 0.83 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr1_+_203274639 0.82 ENST00000290551.4
BTG2
BTG family, member 2
chr1_+_150954493 0.77 ENST00000368947.4
ANXA9
annexin A9
chr6_+_151358048 0.76 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr14_-_102552659 0.76 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr6_+_125524785 0.76 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr3_+_179322481 0.75 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr8_+_98881268 0.74 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr1_+_196621002 0.73 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr1_+_155583012 0.73 ENST00000462250.2
MSTO1
misato 1, mitochondrial distribution and morphology regulator
chr12_+_6930964 0.72 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr12_+_6930813 0.72 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr15_-_45422056 0.72 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr14_+_74551650 0.71 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr14_-_58893876 0.71 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_-_795170 0.70 ENST00000481290.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr5_+_112849373 0.69 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr2_+_230787213 0.68 ENST00000409992.1
FBXO36
F-box protein 36
chr22_-_29138386 0.68 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr1_+_145726886 0.67 ENST00000443667.1
PDZK1
PDZ domain containing 1
chr12_+_102514019 0.66 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr13_+_41635617 0.66 ENST00000542082.1
WBP4
WW domain binding protein 4
chr3_+_184055240 0.66 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr5_-_162887071 0.66 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr11_+_111896090 0.65 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr3_-_179322416 0.64 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr22_-_37584321 0.63 ENST00000397110.2
ENST00000337843.2
C1QTNF6
C1q and tumor necrosis factor related protein 6
chr8_+_110552831 0.62 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr14_+_58765103 0.62 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr1_+_32827759 0.62 ENST00000373534.3
TSSK3
testis-specific serine kinase 3
chr14_+_38065052 0.61 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr11_-_119066545 0.60 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr1_+_196621156 0.60 ENST00000359637.2
CFH
complement factor H
chr1_-_11907829 0.60 ENST00000376480.3
NPPA
natriuretic peptide A
chr13_+_76123883 0.59 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_-_114245938 0.58 ENST00000602447.1
KIAA0368
KIAA0368
chr12_+_27849378 0.58 ENST00000310791.2
REP15
RAB15 effector protein
chr11_+_66624527 0.58 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr14_+_88851874 0.58 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr12_-_88535747 0.57 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr17_+_37894179 0.57 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr19_+_38880695 0.56 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr9_-_104249319 0.56 ENST00000374847.1
TMEM246
transmembrane protein 246
chr7_+_94536898 0.55 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr7_+_73868439 0.55 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr1_+_70876926 0.55 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr11_-_119599794 0.55 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr20_+_57875457 0.53 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr19_-_41196534 0.53 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr6_-_89673280 0.53 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr3_-_49726104 0.51 ENST00000383728.3
ENST00000545762.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_+_100187196 0.51 ENST00000468962.1
ENST00000427939.2
FBXO24
F-box protein 24
chr21_+_17566643 0.51 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr22_+_23487513 0.49 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr6_-_31745037 0.49 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr11_+_111896320 0.48 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr5_-_145483932 0.48 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr12_-_12715266 0.47 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr17_-_41132088 0.46 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr22_-_29137771 0.46 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr7_+_128312346 0.46 ENST00000480462.1
ENST00000378704.3
ENST00000477515.1
FAM71F2
family with sequence similarity 71, member F2
chr7_+_102389434 0.46 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr12_-_111926342 0.45 ENST00000389154.3
ATXN2
ataxin 2
chr1_-_244006528 0.45 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr2_+_219745020 0.44 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr17_-_74489215 0.43 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr2_+_85661918 0.43 ENST00000340326.2
SH2D6
SH2 domain containing 6
chr14_-_82000140 0.43 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr12_-_96184533 0.42 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr17_-_7082668 0.42 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chr20_+_56884752 0.42 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr14_-_89021077 0.42 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr15_+_48413211 0.42 ENST00000449382.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr10_+_11784360 0.42 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr3_+_127317945 0.42 ENST00000472731.1
MCM2
minichromosome maintenance complex component 2
chr8_+_63161491 0.42 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr2_-_86790472 0.41 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chrX_-_39956656 0.41 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chr3_-_194207388 0.41 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr10_+_99332529 0.40 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr12_+_7072354 0.40 ENST00000537269.1
U47924.27
U47924.27
chr3_-_179322436 0.40 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr3_-_49726486 0.39 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_-_72374848 0.39 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr4_+_159122728 0.39 ENST00000505049.1
ENST00000505189.1
ENST00000511038.1
TMEM144
transmembrane protein 144
chr12_+_41221975 0.39 ENST00000552913.1
CNTN1
contactin 1
chr16_+_28875126 0.39 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr10_-_76859247 0.38 ENST00000472493.2
ENST00000605915.1
ENST00000478873.2
DUSP13
dual specificity phosphatase 13
chr2_+_32853093 0.38 ENST00000448773.1
ENST00000317907.4
TTC27
tetratricopeptide repeat domain 27
chr10_+_63808970 0.38 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr12_+_122018697 0.38 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr20_+_57875758 0.37 ENST00000395654.3
EDN3
endothelin 3
chr14_-_104028595 0.37 ENST00000337322.4
ENST00000445922.2
BAG5
BCL2-associated athanogene 5
chr16_-_58328923 0.37 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr21_+_34697258 0.37 ENST00000442071.1
ENST00000442357.2
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr8_-_99954788 0.37 ENST00000523601.1
STK3
serine/threonine kinase 3
chr14_-_104029013 0.36 ENST00000299204.4
ENST00000557666.1
BAG5
BCL2-associated athanogene 5
chr18_+_3262954 0.36 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr2_-_179315490 0.36 ENST00000487082.1
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr16_-_2379688 0.36 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr9_+_139685782 0.36 ENST00000290079.8
ENST00000456614.2
TMEM141
RP11-216L13.17
transmembrane protein 141
RP11-216L13.17
chr12_-_80328949 0.35 ENST00000450142.2
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr2_-_179315453 0.35 ENST00000432031.2
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr3_-_45957088 0.35 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr3_-_48471454 0.35 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr2_-_61389168 0.35 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
RP11-493E12.1
chr19_+_16187085 0.35 ENST00000300933.4
TPM4
tropomyosin 4
chr8_+_104033296 0.35 ENST00000521514.1
ENST00000518738.1
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr19_+_19639670 0.35 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr8_+_27632047 0.35 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_+_57914742 0.35 ENST00000551351.1
MBD6
methyl-CpG binding domain protein 6
chr10_-_52645416 0.34 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr3_+_164924716 0.34 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
RP11-85M11.2
chr5_+_145583156 0.34 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr11_+_65190245 0.33 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_100862811 0.33 ENST00000303130.2
TMEM133
transmembrane protein 133
chr9_+_125133315 0.33 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_+_66276550 0.33 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr4_+_48343339 0.33 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr1_-_109940550 0.33 ENST00000256637.6
SORT1
sortilin 1
chr14_-_55369525 0.32 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1
GTP cyclohydrolase 1
chr8_-_53626974 0.32 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr16_-_58328870 0.32 ENST00000543437.1
PRSS54
protease, serine, 54
chr22_-_33968239 0.32 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr11_-_73720122 0.32 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr1_+_17531614 0.31 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr6_-_31745085 0.31 ENST00000375686.3
ENST00000447450.1
VWA7
von Willebrand factor A domain containing 7
chr1_+_171810606 0.31 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr2_-_165698662 0.31 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr3_-_197025447 0.31 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr16_-_29757272 0.31 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr12_-_122907091 0.31 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
CLIP1
CAP-GLY domain containing linker protein 1
chr15_+_45422131 0.30 ENST00000321429.4
DUOX1
dual oxidase 1
chr11_-_64013663 0.30 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_+_35851570 0.30 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr1_-_175162048 0.30 ENST00000444639.1
KIAA0040
KIAA0040
chr11_-_27722021 0.30 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
BDNF
brain-derived neurotrophic factor
chr3_-_98241713 0.30 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
CLDND1
claudin domain containing 1
chr3_-_98241760 0.29 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr9_-_88874519 0.29 ENST00000376001.3
ENST00000339137.3
C9orf153
chromosome 9 open reading frame 153
chr17_+_42836521 0.29 ENST00000535346.1
ADAM11
ADAM metallopeptidase domain 11
chr12_+_11905413 0.29 ENST00000545027.1
ETV6
ets variant 6
chr1_-_204329013 0.29 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr12_+_6930703 0.29 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chrX_+_67913471 0.29 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr13_-_76111945 0.29 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr9_+_140145713 0.29 ENST00000388931.3
ENST00000412566.1
C9orf173
chromosome 9 open reading frame 173
chr19_-_41196458 0.28 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr9_-_88897426 0.28 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr15_-_83315874 0.28 ENST00000569257.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr2_+_179316163 0.28 ENST00000409117.3
DFNB59
deafness, autosomal recessive 59
chr3_+_179322573 0.28 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr19_+_19639704 0.28 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr11_-_117699413 0.28 ENST00000528014.1
FXYD2
FXYD domain containing ion transport regulator 2
chr3_+_14989186 0.28 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr15_+_45422178 0.28 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr15_+_48413169 0.28 ENST00000341459.3
ENST00000482911.2
SLC24A5
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr2_-_33824382 0.28 ENST00000238823.8
FAM98A
family with sequence similarity 98, member A
chr6_+_64346386 0.28 ENST00000509330.1
PHF3
PHD finger protein 3
chr2_-_55459437 0.27 ENST00000401408.1
CLHC1
clathrin heavy chain linker domain containing 1
chr9_+_35042205 0.27 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chr11_-_77123065 0.27 ENST00000530617.1
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr1_+_70876891 0.27 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr9_+_131452239 0.27 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr16_-_50715239 0.26 ENST00000330943.4
ENST00000300590.3
SNX20
sorting nexin 20
chr5_+_170288856 0.26 ENST00000523189.1
RANBP17
RAN binding protein 17
chr8_+_63161550 0.26 ENST00000328472.5
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr2_+_173686303 0.26 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_+_32655110 0.26 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.4 1.2 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.4 1.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.5 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 1.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 1.9 GO:0015793 glycerol transport(GO:0015793)
0.2 1.0 GO:0060032 notochord regression(GO:0060032)
0.2 1.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.2 3.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 0.8 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.8 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 1.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 1.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 0.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 0.8 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.6 GO:1904048 positive regulation of long term synaptic depression(GO:1900454) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.7 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.7 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.6 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.5 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.4 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.4 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.7 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 1.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 1.2 GO:0006477 protein sulfation(GO:0006477)
0.1 0.6 GO:0042335 cuticle development(GO:0042335)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.5 GO:0030238 male sex determination(GO:0030238)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 1.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 1.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 2.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.6 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.8 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.7 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0008582 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.2 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.9 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0071306 regulation of cholesterol transporter activity(GO:0060694) cellular response to vitamin E(GO:0071306) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.8 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 1.2 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0097152 mesenchymal cell apoptotic process(GO:0097152)
0.0 0.0 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.6 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.7 GO:0008347 glial cell migration(GO:0008347)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 1.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.1 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.6 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 3.0 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.1 0.9 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.4 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0010369 chromocenter(GO:0010369)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 1.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0015254 glycerol channel activity(GO:0015254)
0.4 1.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 1.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 1.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.6 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.2 1.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 1.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 0.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.7 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.4 GO:0019961 interferon binding(GO:0019961)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.9 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.9 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.8 GO:0030911 TPR domain binding(GO:0030911)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 1.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.8 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 2.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.0 PID ATM PATHWAY ATM pathway
0.0 2.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.3 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions