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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TLX1_NFIC

Z-value: 2.01

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.8 T cell leukemia homeobox 1
NFIC
ENSG00000141905.13 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg19_v2_chr19_+_3359561_3359681-0.752.5e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_64764435 4.46 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr15_+_90735145 2.83 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_+_79086088 2.61 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr17_+_74372662 2.51 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr11_-_71751715 1.60 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr17_+_7344057 1.58 ENST00000575398.1
ENST00000575082.1
FGF11
fibroblast growth factor 11
chr7_+_22766766 1.49 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr17_+_19314432 1.43 ENST00000575165.2
RNF112
ring finger protein 112
chr1_-_200992827 1.43 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr21_+_33784670 1.29 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr19_+_10397648 1.24 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr1_-_153363452 1.23 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr8_-_42065075 1.22 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr19_+_10397621 1.18 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr5_-_176923803 1.17 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr1_+_79115503 1.16 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr22_-_39640756 1.16 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr11_-_65149422 1.15 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr6_-_43595039 1.15 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr12_-_54813229 1.14 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr18_+_21529811 1.13 ENST00000588004.1
LAMA3
laminin, alpha 3
chr8_-_42065187 1.13 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr7_-_75241096 1.11 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr21_+_33784957 1.07 ENST00000401402.3
ENST00000382699.3
EVA1C
eva-1 homolog C (C. elegans)
chr19_+_677885 1.03 ENST00000591552.2
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr5_-_176923846 1.02 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr22_+_46449674 1.00 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr7_+_143079000 1.00 ENST00000392910.2
ZYX
zyxin
chr15_+_89182178 0.96 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_113217345 0.95 ENST00000357443.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr7_+_143078652 0.95 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr11_+_18417948 0.91 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr15_+_89182156 0.90 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr20_-_60942326 0.88 ENST00000370677.3
ENST00000370692.3
LAMA5
laminin, alpha 5
chr2_-_233877912 0.87 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr1_+_113217073 0.86 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217043 0.85 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_+_89181974 0.83 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_39456895 0.80 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr11_+_18417813 0.78 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr20_-_60942361 0.77 ENST00000252999.3
LAMA5
laminin, alpha 5
chr16_-_51185149 0.77 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr16_-_19896150 0.74 ENST00000570142.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr22_-_37213045 0.72 ENST00000406910.2
ENST00000417718.2
PVALB
parvalbumin
chr11_-_71752571 0.71 ENST00000544238.1
NUMA1
nuclear mitotic apparatus protein 1
chr5_+_32531893 0.71 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr22_-_30662828 0.66 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr1_+_200993071 0.65 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr12_+_13349711 0.65 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr1_+_113217309 0.63 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr12_+_13349650 0.62 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr8_+_61822605 0.62 ENST00000526936.1
AC022182.1
AC022182.1
chr16_-_46797149 0.62 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr9_-_98268883 0.60 ENST00000551630.1
ENST00000548420.1
PTCH1
patched 1
chrX_-_53310791 0.60 ENST00000375365.2
IQSEC2
IQ motif and Sec7 domain 2
chr2_+_27071292 0.59 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr6_+_123100620 0.58 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr1_+_19967014 0.58 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chrX_+_46937745 0.58 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr19_-_33716750 0.57 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr14_+_24867992 0.56 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr19_-_41388657 0.56 ENST00000301146.4
ENST00000291764.3
CYP2A7
cytochrome P450, family 2, subfamily A, polypeptide 7
chr11_-_33913708 0.56 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chrX_-_102319092 0.55 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr8_-_141728444 0.55 ENST00000521562.1
PTK2
protein tyrosine kinase 2
chr8_-_80680078 0.54 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr12_-_109797249 0.52 ENST00000538041.1
RP11-256L11.1
RP11-256L11.1
chr6_-_30043539 0.51 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr7_-_100076873 0.50 ENST00000300181.2
TSC22D4
TSC22 domain family, member 4
chr17_-_26903900 0.50 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chrX_+_102631248 0.48 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr6_+_31950150 0.48 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr9_-_132515302 0.48 ENST00000340607.4
PTGES
prostaglandin E synthase
chr8_+_102064237 0.47 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr1_-_41950342 0.47 ENST00000372587.4
EDN2
endothelin 2
chr20_+_61299155 0.47 ENST00000451793.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr19_-_12946215 0.46 ENST00000591512.1
ENST00000587549.1
ENST00000322912.5
RTBDN
retbindin
chr17_+_77030267 0.46 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr8_+_94752349 0.45 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr2_+_220325977 0.45 ENST00000396686.1
ENST00000396689.2
SPEG
SPEG complex locus
chr2_-_217560248 0.45 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr1_+_110453109 0.44 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chrX_+_52240504 0.44 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr19_+_40195101 0.44 ENST00000360675.3
ENST00000601802.1
LGALS14
lectin, galactoside-binding, soluble, 14
chrX_-_52258669 0.44 ENST00000441417.1
XAGE1A
X antigen family, member 1A
chr1_-_109399682 0.43 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr18_+_33877654 0.43 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr17_-_39677971 0.43 ENST00000393976.2
KRT15
keratin 15
chr2_+_7017796 0.43 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr19_-_1155118 0.43 ENST00000590998.1
SBNO2
strawberry notch homolog 2 (Drosophila)
chr15_-_72523924 0.42 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM
pyruvate kinase, muscle
chr16_+_30751953 0.41 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr15_+_45926919 0.41 ENST00000561735.1
ENST00000260324.7
SQRDL
sulfide quinone reductase-like (yeast)
chr5_-_115872142 0.41 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_52513455 0.40 ENST00000446098.1
XAGE1C
X antigen family, member 1C
chr5_+_150020240 0.40 ENST00000519664.1
SYNPO
synaptopodin
chr7_-_27187393 0.40 ENST00000222728.3
HOXA6
homeobox A6
chr11_-_62313090 0.40 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr15_-_59665062 0.40 ENST00000288235.4
MYO1E
myosin IE
chr3_-_12200851 0.39 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr1_+_44514040 0.39 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4
RP5-1198O20.4
chr11_-_128457446 0.39 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr15_+_90728145 0.39 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr10_-_104597286 0.39 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr17_-_76921459 0.39 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr15_-_72523454 0.38 ENST00000565154.1
ENST00000565184.1
ENST00000389093.3
ENST00000449901.2
ENST00000335181.5
ENST00000319622.6
PKM
pyruvate kinase, muscle
chrX_-_52531609 0.38 ENST00000438079.1
XAGE1D
X antigen family, member 1D
chr19_-_35454953 0.38 ENST00000404801.1
ZNF792
zinc finger protein 792
chr17_+_7462103 0.38 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_+_50936142 0.38 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr20_+_43343886 0.37 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr1_-_16539094 0.37 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr6_-_16761678 0.37 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr11_-_65325430 0.37 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr1_-_229569834 0.36 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr17_+_7461849 0.36 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr20_+_43343517 0.36 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr8_+_22022653 0.36 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
BMP1
bone morphogenetic protein 1
chr7_-_100076765 0.36 ENST00000393991.1
TSC22D4
TSC22 domain family, member 4
chr20_+_43343476 0.34 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr12_+_66217911 0.34 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chrX_-_154376044 0.33 ENST00000362018.2
MTCP1
mature T-cell proliferation 1
chr10_+_124320156 0.33 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr1_-_113247543 0.33 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chrX_-_83757399 0.33 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr9_+_34646624 0.32 ENST00000450095.2
ENST00000556278.1
GALT
GALT
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr5_-_111093081 0.32 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr8_-_145701718 0.32 ENST00000377317.4
FOXH1
forkhead box H1
chr15_-_40213080 0.32 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr7_-_7575477 0.32 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr17_-_48474828 0.31 ENST00000576448.1
ENST00000225972.7
LRRC59
leucine rich repeat containing 59
chr20_+_33759854 0.31 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr1_+_168250194 0.31 ENST00000367821.3
TBX19
T-box 19
chr17_+_19314505 0.31 ENST00000461366.1
RNF112
ring finger protein 112
chr2_+_10442993 0.31 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr2_+_233385173 0.31 ENST00000449534.2
PRSS56
protease, serine, 56
chr1_-_32169920 0.31 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr1_-_44497118 0.30 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_150020214 0.30 ENST00000307662.4
SYNPO
synaptopodin
chr1_-_32169761 0.30 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr1_-_92949505 0.30 ENST00000370332.1
GFI1
growth factor independent 1 transcription repressor
chr17_-_42992856 0.30 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr8_+_22022800 0.30 ENST00000397814.3
BMP1
bone morphogenetic protein 1
chr2_+_220325441 0.29 ENST00000396688.1
SPEG
SPEG complex locus
chr17_+_7461781 0.29 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr3_+_63953415 0.28 ENST00000484332.1
ATXN7
ataxin 7
chr22_-_24641027 0.28 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5
gamma-glutamyltransferase 5
chr6_+_123100853 0.28 ENST00000356535.4
FABP7
fatty acid binding protein 7, brain
chr7_-_5463175 0.28 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr1_-_27816556 0.27 ENST00000536657.1
WASF2
WAS protein family, member 2
chr16_+_222846 0.27 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr5_+_52083730 0.26 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr7_+_128355439 0.26 ENST00000315184.5
FAM71F1
family with sequence similarity 71, member F1
chr9_+_34646651 0.26 ENST00000378842.3
GALT
galactose-1-phosphate uridylyltransferase
chr12_+_57522439 0.26 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chrX_+_102631844 0.25 ENST00000372634.1
ENST00000299872.7
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr4_+_130014836 0.25 ENST00000502887.1
C4orf33
chromosome 4 open reading frame 33
chr19_+_45202421 0.25 ENST00000587331.1
CEACAM16
carcinoembryonic antigen-related cell adhesion molecule 16
chr17_+_72428218 0.25 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_111637083 0.25 ENST00000427203.2
ENST00000341980.6
ENST00000311129.5
ENST00000393055.2
ENST00000426998.2
ENST00000527614.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr1_-_32264250 0.25 ENST00000528579.1
SPOCD1
SPOC domain containing 1
chr11_-_10829851 0.24 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr19_+_4007644 0.24 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr19_-_6737576 0.24 ENST00000601716.1
ENST00000264080.7
GPR108
G protein-coupled receptor 108
chr7_-_100065686 0.24 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr19_+_1491144 0.24 ENST00000233596.3
REEP6
receptor accessory protein 6
chr6_+_34204642 0.24 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr6_+_150920999 0.23 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr19_+_16222439 0.23 ENST00000300935.3
RAB8A
RAB8A, member RAS oncogene family
chr5_-_111093340 0.22 ENST00000508870.1
NREP
neuronal regeneration related protein
chr22_+_50639408 0.22 ENST00000380903.2
SELO
Selenoprotein O
chr16_-_2264779 0.22 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr19_-_42927251 0.22 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr5_+_140855495 0.22 ENST00000308177.3
PCDHGC3
protocadherin gamma subfamily C, 3
chr11_+_61717279 0.21 ENST00000378043.4
BEST1
bestrophin 1
chr12_-_53228079 0.21 ENST00000330553.5
KRT79
keratin 79
chr14_+_85996507 0.21 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_-_81399438 0.21 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_31982539 0.21 ENST00000435363.2
ENST00000425700.2
C4B
complement component 4B (Chido blood group)
chr14_-_36645674 0.21 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr16_+_57653625 0.21 ENST00000567553.1
ENST00000565314.1
GPR56
G protein-coupled receptor 56
chr1_-_242612726 0.21 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr22_+_40390930 0.21 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chrX_-_54522558 0.21 ENST00000375135.3
FGD1
FYVE, RhoGEF and PH domain containing 1
chr2_-_25475120 0.20 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chrX_-_154688276 0.20 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr9_+_102584128 0.20 ENST00000338488.4
ENST00000395097.2
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr22_-_20368028 0.20 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr6_+_31949801 0.20 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr17_+_79369249 0.20 ENST00000574717.2
RP11-1055B8.6
Uncharacterized protein
chr19_+_36606354 0.20 ENST00000589996.1
ENST00000591296.1
TBCB
tubulin folding cofactor B
chr17_-_41910505 0.20 ENST00000398389.4
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr11_-_68611721 0.20 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr20_+_9049742 0.19 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr16_-_8962853 0.19 ENST00000565287.1
ENST00000311052.5
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr1_+_95975672 0.19 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr1_+_153747746 0.19 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr6_+_135502501 0.19 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_+_110834033 0.19 ENST00000509793.1
ENST00000265171.5
EGF
epidermal growth factor
chr10_+_135160844 0.19 ENST00000423766.1
ENST00000458230.1
PRAP1
proline-rich acidic protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.5 2.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.5 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.4 1.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.3 3.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.2 GO:0090678 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 2.3 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2 0.6 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 4.5 GO:0042832 defense response to protozoan(GO:0042832)
0.2 0.6 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.5 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 0.5 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 1.2 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 1.1 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.6 GO:0010157 response to chlorate(GO:0010157)
0.1 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 1.2 GO:0009615 response to virus(GO:0009615)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.6 GO:0097168 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.5 GO:0021553 olfactory nerve development(GO:0021553) olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 2.4 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.8 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.7 GO:0002544 chronic inflammatory response(GO:0002544)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 1.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 2.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.3 GO:0061107 seminal vesicle development(GO:0061107)
0.1 0.2 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0030578 PML body organization(GO:0030578)
0.0 0.9 GO:0060134 prepulse inhibition(GO:0060134)
0.0 1.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 1.3 GO:0032060 bleb assembly(GO:0032060)
0.0 3.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.2 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 1.7 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.0 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:2000504 negative regulation of Fas signaling pathway(GO:1902045) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 0.1 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.6 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.3 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 1.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0001711 endodermal cell fate commitment(GO:0001711) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0043260 laminin-11 complex(GO:0043260)
0.3 1.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 0.7 GO:0097444 spine apparatus(GO:0097444)
0.2 2.3 GO:0055028 cortical microtubule(GO:0055028)
0.2 0.8 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.3 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.1 0.4 GO:0030017 sarcomere(GO:0030017)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.3 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 4.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 3.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 2.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 3.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 4.9 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 3.3 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 2.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 3.0 GO:0004386 helicase activity(GO:0004386)
0.0 1.1 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 3.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 2.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 5.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.7 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR