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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TP53

Z-value: 1.58

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Transcription factors associated with TP53

Gene Symbol Gene ID Gene Info
ENSG00000141510.11 tumor protein p53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP53hg19_v2_chr17_-_7590745_75908560.891.1e-01Click!

Activity profile of TP53 motif

Sorted Z-values of TP53 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_53207842 1.88 ENST00000458244.2
keratin 4
chr10_-_90751038 1.36 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr17_+_76210267 1.29 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
baculoviral IAP repeat containing 5
chr19_+_28284803 1.22 ENST00000586220.1
ENST00000588784.1
ENST00000591549.1
ENST00000585827.1
ENST00000588636.1
ENST00000587188.1
CTC-459F4.3
chr16_-_75467274 1.19 ENST00000566254.1
craniofacial development protein 1
chrX_-_65858865 1.19 ENST00000374719.3
ENST00000450752.1
ENST00000451436.2
ectodysplasin A2 receptor
chr5_+_162864575 1.12 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr9_+_139846708 1.09 ENST00000371633.3
lipocalin 12
chr19_-_47735918 1.08 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BCL2 binding component 3
chr6_-_138428613 0.98 ENST00000421351.3
PERP, TP53 apoptosis effector
chr15_+_89164560 0.96 ENST00000379231.3
ENST00000559528.1
apoptosis enhancing nuclease
chr15_+_89164520 0.88 ENST00000332810.3
apoptosis enhancing nuclease
chr19_+_15783879 0.88 ENST00000551607.1
cytochrome P450, family 4, subfamily F, polypeptide 12
chrX_-_106959631 0.85 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr5_+_27472371 0.82 ENST00000512067.1
ENST00000510165.1
ENST00000505775.1
ENST00000514844.1
ENST00000503107.1
long intergenic non-protein coding RNA 1021
chr9_-_95527079 0.81 ENST00000356884.6
ENST00000375512.3
bicaudal D homolog 2 (Drosophila)
chr2_+_197504278 0.80 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
coiled-coil domain containing 150
chr20_-_5100591 0.80 ENST00000379143.5
proliferating cell nuclear antigen
chr1_+_117910047 0.79 ENST00000356554.3
mannosidase, alpha, class 1A, member 2
chr8_+_120428546 0.79 ENST00000259526.3
nephroblastoma overexpressed
chr3_+_184279566 0.78 ENST00000330394.2
EPH receptor B3
chr1_+_2477831 0.77 ENST00000606645.1
RP3-395M20.12
chr7_-_21985489 0.76 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
cell division cycle associated 7-like
chr7_+_92861653 0.70 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
coiled-coil domain containing 132
chr12_+_69202795 0.69 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2 oncogene, E3 ubiquitin protein ligase
chr13_+_48877895 0.68 ENST00000267163.4
retinoblastoma 1
chr14_+_97263641 0.68 ENST00000216639.3
vaccinia related kinase 1
chr12_-_126467906 0.68 ENST00000507313.1
ENST00000545784.1
long intergenic non-protein coding RNA 939
chr1_-_54519134 0.67 ENST00000371341.1
transmembrane protein 59
chr3_+_44379944 0.66 ENST00000396078.3
ENST00000342649.4
T cell activation inhibitor, mitochondrial
chr1_-_244615425 0.62 ENST00000366535.3
adenylosuccinate synthase
chr6_-_101329191 0.62 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
activating signal cointegrator 1 complex subunit 3
chr1_+_25598872 0.61 ENST00000328664.4
Rh blood group, D antigen
chr2_-_157198860 0.61 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr10_+_96305535 0.61 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
helicase, lymphoid-specific
chr16_-_14788526 0.58 ENST00000438167.3
phospholipase A2, group X
chr19_-_28284793 0.58 ENST00000590523.1
long intergenic non-protein coding RNA 662
chr3_-_46037299 0.58 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr1_-_38412683 0.57 ENST00000373024.3
ENST00000373023.2
inositol polyphosphate-5-phosphatase, 75kDa
chr7_-_23145288 0.56 ENST00000419813.1
KLHL7 antisense RNA 1 (head to head)
chr22_+_29168652 0.56 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr11_+_64073699 0.56 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr22_-_24093267 0.54 ENST00000341976.3
zinc finger protein 70
chr6_-_30709980 0.53 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
flotillin 1
chr20_-_23807358 0.53 ENST00000304725.2
cystatin SA
chr19_+_49458107 0.51 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr5_+_72861560 0.51 ENST00000296792.4
ENST00000509005.1
ENST00000543251.1
ENST00000508686.1
ENST00000508491.1
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr1_+_114447763 0.51 ENST00000369563.3
DNA cross-link repair 1B
chr17_-_74528128 0.50 ENST00000590175.1
cytoglobin
chr11_+_827553 0.50 ENST00000528542.2
ENST00000450448.1
EF-hand calcium binding domain 4A
chr9_+_139847347 0.49 ENST00000371632.3
lipocalin 12
chr2_+_11295624 0.48 ENST00000402361.1
ENST00000428481.1
PQ loop repeat containing 3
chr14_+_64971292 0.46 ENST00000358738.3
ENST00000394712.2
zinc finger and BTB domain containing 1
chr11_+_827248 0.46 ENST00000527089.1
ENST00000530183.1
EF-hand calcium binding domain 4A
chr3_+_44379611 0.46 ENST00000383746.3
ENST00000417237.1
T cell activation inhibitor, mitochondrial
chr18_-_28622699 0.46 ENST00000360428.4
desmocollin 3
chr19_-_6481776 0.46 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENN/MADD domain containing 1C
chr1_-_54519067 0.45 ENST00000452421.1
ENST00000420738.1
ENST00000234831.5
ENST00000440019.1
transmembrane protein 59
chr3_-_113464906 0.45 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_11295498 0.44 ENST00000295083.3
ENST00000441908.2
PQ loop repeat containing 3
chrX_+_40440146 0.44 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATPase, H+ transporting, lysosomal accessory protein 2
chr15_-_56035177 0.44 ENST00000389286.4
ENST00000561292.1
protogenin
chr18_-_28622774 0.43 ENST00000434452.1
desmocollin 3
chr10_+_88854926 0.43 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr1_+_204494618 0.43 ENST00000367180.1
ENST00000391947.2
Mdm4 p53 binding protein homolog (mouse)
chr2_+_169312725 0.43 ENST00000392687.4
ceramide synthase 6
chr17_-_61523622 0.42 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
cytochrome b561
chr14_+_36295638 0.42 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr14_-_102553371 0.42 ENST00000553585.1
ENST00000216281.8
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr2_+_85661918 0.42 ENST00000340326.2
SH2 domain containing 6
chr16_-_4303767 0.42 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
chr10_+_64564469 0.42 ENST00000373783.1
2-aminoethanethiol (cysteamine) dioxygenase
chr19_+_13988061 0.41 ENST00000339133.5
ENST00000397555.2
nanos homolog 3 (Drosophila)
chr16_+_57653854 0.41 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
G protein-coupled receptor 56
chr7_-_56101826 0.41 ENST00000421626.1
phosphoserine phosphatase
chr12_+_69202975 0.39 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_-_213189168 0.39 ENST00000366962.3
ENST00000360506.2
angel homolog 2 (Drosophila)
chr17_-_5095126 0.38 ENST00000576772.1
ENST00000575779.1
zinc finger protein 594
chr9_+_104161123 0.38 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
zinc finger protein 189
chr1_+_203830703 0.37 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr6_-_109804412 0.37 ENST00000230122.3
zinc finger and BTB domain containing 24
chr12_-_59314246 0.37 ENST00000320743.3
leucine-rich repeats and immunoglobulin-like domains 3
chr20_-_1373606 0.37 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FK506 binding protein 1A, 12kDa
chr15_-_63448973 0.37 ENST00000462430.1
ribosomal protein S27-like
chr6_-_101329157 0.36 ENST00000369143.2
activating signal cointegrator 1 complex subunit 3
chr4_+_26859300 0.36 ENST00000494628.2
stromal interaction molecule 2
chr18_+_44497455 0.36 ENST00000592005.1
katanin p60 subunit A-like 2
chr17_-_61523535 0.36 ENST00000584031.1
ENST00000392976.1
cytochrome b561
chr9_-_115774453 0.36 ENST00000427548.1
zinc finger protein 883
chr22_+_42949925 0.34 ENST00000327678.5
ENST00000340239.4
ENST00000407614.4
ENST00000335879.5
serine hydrolase-like 2
chr20_+_57467204 0.34 ENST00000603546.1
GNAS complex locus
chr3_-_44519131 0.33 ENST00000425708.2
ENST00000396077.2
zinc finger protein 445
chr8_+_95732095 0.33 ENST00000414645.2
dpy-19-like 4 (C. elegans)
chr7_-_102789629 0.33 ENST00000417955.1
ENST00000341533.4
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr12_+_99038998 0.33 ENST00000359972.2
ENST00000357310.1
ENST00000339433.3
ENST00000333991.1
apoptotic peptidase activating factor 1
chr20_-_43589109 0.33 ENST00000372813.3
translocase of outer mitochondrial membrane 34
chr4_+_6784401 0.33 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr17_-_4900873 0.32 ENST00000355025.3
ENST00000575780.1
ENST00000396829.2
inhibitor of CDK, cyclin A1 interacting protein 1
chr8_-_23021533 0.32 ENST00000312584.3
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr4_-_187644930 0.32 ENST00000441802.2
FAT atypical cadherin 1
chr20_-_1373682 0.31 ENST00000381724.3
FK506 binding protein 1A, 12kDa
chr13_-_50367057 0.31 ENST00000261667.3
karyopherin alpha 3 (importin alpha 4)
chr4_+_41937131 0.31 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr5_-_72861175 0.30 ENST00000504641.1
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_24403144 0.30 ENST00000274747.7
ENST00000543597.1
ENST00000535061.1
ENST00000378353.1
ENST00000378386.3
ENST00000443868.2
MRS2 magnesium transporter
chr9_+_80912059 0.29 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr10_-_88854518 0.29 ENST00000277865.4
glutamate dehydrogenase 1
chr9_-_104160872 0.29 ENST00000539624.1
ENST00000374865.4
mitochondrial ribosomal protein L50
chr9_-_140115775 0.29 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr7_-_100239132 0.29 ENST00000223051.3
ENST00000431692.1
transferrin receptor 2
chr14_-_36789783 0.28 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr10_-_105212141 0.28 ENST00000369788.3
calcium homeostasis modulator 2
chr2_+_169312350 0.28 ENST00000305747.6
ceramide synthase 6
chr6_+_33378517 0.28 ENST00000428274.1
PHD finger protein 1
chr16_+_57653989 0.28 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr1_-_205744574 0.27 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr1_-_1356719 0.27 ENST00000520296.1
ankyrin repeat domain 65
chr1_-_114447620 0.27 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
adaptor-related protein complex 4, beta 1 subunit
chr11_-_44972476 0.27 ENST00000527685.1
ENST00000308212.5
tumor protein p53 inducible protein 11
chr10_+_96305610 0.27 ENST00000371332.4
ENST00000239026.6
helicase, lymphoid-specific
chr12_-_14721283 0.27 ENST00000240617.5
phospholipase B domain containing 1
chrX_+_134478706 0.27 ENST00000370761.3
ENST00000339249.4
ENST00000370760.3
zinc finger protein 449
chr17_+_14204389 0.26 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr8_+_22429205 0.26 ENST00000520207.1
sorbin and SH3 domain containing 3
chr7_+_23145884 0.26 ENST00000409689.1
ENST00000410047.1
kelch-like family member 7
chr14_+_64970662 0.26 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr1_-_1356628 0.25 ENST00000442470.1
ENST00000537107.1
ankyrin repeat domain 65
chr22_-_28392227 0.25 ENST00000431039.1
tetratricopeptide repeat domain 28
chr2_-_167232484 0.24 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr3_-_52804872 0.24 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NIMA-related kinase 4
chr19_+_55999916 0.24 ENST00000587166.1
ENST00000389623.6
scavenger receptor cysteine rich domain containing (5 domains)
chr1_-_153588334 0.24 ENST00000476873.1
S100 calcium binding protein A14
chr11_-_44972390 0.24 ENST00000395648.3
ENST00000531928.2
tumor protein p53 inducible protein 11
chr16_+_77756399 0.24 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr19_-_2456922 0.24 ENST00000582871.1
ENST00000325327.3
lamin B2
chr7_+_75024903 0.23 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr11_+_1855645 0.23 ENST00000381968.3
ENST00000381978.3
synaptotagmin VIII
chr8_-_12612962 0.23 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chrX_-_70474499 0.23 ENST00000353904.2
zinc finger, MYM-type 3
chr5_-_72861484 0.23 ENST00000296785.3
ankyrin repeat, family A (RFXANK-like), 2
chr17_-_72855989 0.23 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr1_-_54411240 0.22 ENST00000371378.2
heat shock protein family B (small), member 11
chr1_+_17634689 0.22 ENST00000375453.1
ENST00000375448.4
peptidyl arginine deiminase, type IV
chr2_-_75788428 0.22 ENST00000432649.1
eva-1 homolog A (C. elegans)
chr1_-_26197744 0.22 ENST00000374296.3
progestin and adipoQ receptor family member VII
chrX_-_70474377 0.22 ENST00000373978.1
ENST00000373981.1
zinc finger, MYM-type 3
chr11_-_129062093 0.22 ENST00000310343.9
Rho GTPase activating protein 32
chr1_-_25747283 0.22 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
Rh blood group, CcEe antigens
chr1_-_243418650 0.21 ENST00000522995.1
centrosomal protein 170kDa
chrX_+_152086373 0.21 ENST00000318529.8
zinc finger protein 185 (LIM domain)
chr4_+_671711 0.21 ENST00000400159.2
myosin, light chain 5, regulatory
chr8_-_22926623 0.21 ENST00000276431.4
tumor necrosis factor receptor superfamily, member 10b
chr11_-_44972418 0.21 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
tumor protein p53 inducible protein 11
chr14_+_24702127 0.20 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
guanosine monophosphate reductase 2
chr11_-_77123065 0.20 ENST00000530617.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr22_-_39715600 0.20 ENST00000427905.1
ENST00000402527.1
ENST00000216146.4
ribosomal protein L3
chr12_+_44229846 0.20 ENST00000551577.1
ENST00000266534.3
transmembrane protein 117
chr17_+_76210367 0.20 ENST00000592734.1
ENST00000587746.1
baculoviral IAP repeat containing 5
chr1_+_27153173 0.20 ENST00000374142.4
zinc finger, DHHC-type containing 18
chr19_+_489140 0.20 ENST00000587541.1
mucosal vascular addressin cell adhesion molecule 1
chr17_+_20483037 0.20 ENST00000399044.1
CMT1A duplicated region transcript 15-like 2
chr1_+_54411715 0.20 ENST00000371370.3
ENST00000371368.1
leucine rich repeat containing 42
chr19_+_51293672 0.20 ENST00000270593.1
ENST00000270594.3
acid phosphatase, testicular
chrX_-_70473957 0.20 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
zinc finger, MYM-type 3
chr8_-_12051576 0.20 ENST00000524571.2
ENST00000533852.2
ENST00000533513.1
ENST00000448228.2
ENST00000534520.1
ENST00000321602.8
family with sequence similarity 86, member B1
chr10_+_11784360 0.19 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr3_+_149530469 0.19 ENST00000392894.3
ENST00000344229.3
ring finger protein 13
chr8_-_144413981 0.19 ENST00000522041.1
topoisomerase (DNA) I, mitochondrial
chr16_-_29874462 0.19 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr17_-_37309480 0.19 ENST00000539608.1
plexin domain containing 1
chr22_-_38484922 0.19 ENST00000428572.1
BAI1-associated protein 2-like 2
chr8_-_69243711 0.19 ENST00000512294.3
HCG1787533; Uncharacterized protein
chr17_+_46918925 0.19 ENST00000502761.1
calcium binding and coiled-coil domain 2
chr3_-_100120223 0.18 ENST00000284320.5
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr11_+_67171358 0.18 ENST00000526387.1
TBC1 domain family, member 10C
chr2_-_85555086 0.18 ENST00000444342.2
ENST00000409232.3
ENST00000409015.1
trans-golgi network protein 2
chr7_+_23145366 0.18 ENST00000339077.5
ENST00000322275.5
ENST00000539124.1
ENST00000542558.1
kelch-like family member 7
chr1_-_202936394 0.18 ENST00000367249.4
cytochrome b5 reductase 1
chr10_+_126490354 0.18 ENST00000298492.5
family with sequence similarity 175, member B
chr14_-_36789865 0.18 ENST00000416007.4
MAP3K12 binding inhibitory protein 1
chr1_+_54411995 0.18 ENST00000319223.4
ENST00000444987.1
leucine rich repeat containing 42
chr11_+_706595 0.17 ENST00000531348.1
ENST00000530636.1
EPS8-like 2
chr17_-_14140166 0.17 ENST00000420162.2
ENST00000431716.2
CMT1A duplicated region transcript 15
chr16_-_29874211 0.17 ENST00000563415.1
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr1_-_205744205 0.17 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr7_+_116165754 0.16 ENST00000405348.1
caveolin 1, caveolae protein, 22kDa
chr14_-_50999307 0.16 ENST00000013125.4
mitogen-activated protein kinase kinase kinase kinase 5
chr12_-_122711968 0.16 ENST00000485724.1
diablo, IAP-binding mitochondrial protein
chr2_-_242556900 0.16 ENST00000402545.1
ENST00000402136.1
THAP domain containing 4
chr1_-_54518865 0.16 ENST00000371337.3
transmembrane protein 59
chr17_+_80332153 0.16 ENST00000313135.2
urotensin 2 receptor
chr10_-_105212059 0.15 ENST00000260743.5
calcium homeostasis modulator 2
chr5_+_141348598 0.15 ENST00000394520.2
ENST00000347642.3
ring finger protein 14
chr8_-_22926526 0.15 ENST00000347739.3
ENST00000542226.1
tumor necrosis factor receptor superfamily, member 10b
chr11_-_68611721 0.15 ENST00000561996.1
carnitine palmitoyltransferase 1A (liver)
chr6_-_111804905 0.15 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr11_+_119039414 0.15 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLR family member X1
chr1_-_114447683 0.14 ENST00000256658.4
ENST00000369564.1
adaptor-related protein complex 4, beta 1 subunit
chr5_+_64920543 0.14 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr14_-_31889782 0.14 ENST00000543095.2
HEAT repeat containing 5A

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.3 0.9 GO:0003095 pressure natriuresis(GO:0003095)
0.3 1.4 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.7 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 0.9 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.8 GO:0006272 leading strand elongation(GO:0006272)
0.2 0.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.5 GO:1902512 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.6 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.6 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.5 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.9 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.7 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.5 GO:0031627 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.1 0.7 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 1.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.4 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.5 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.3 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.1 0.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.1 1.0 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.4 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.9 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.8 GO:0022038 corpus callosum development(GO:0022038)
0.0 2.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 1.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.4 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089) magnesium ion transmembrane transport(GO:1903830)
0.0 0.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0006937 regulation of muscle contraction(GO:0006937)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 1.9 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.3 0.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.2 0.6 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.8 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 0.8 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 0.7 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.5 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.5 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.8 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase