Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for TP73

Z-value: 0.74

Motif logo

logo of

Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.10 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3569129_35691500.653.5e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_62203808 1.31 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr20_+_35504522 0.89 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr17_+_73750699 0.69 ENST00000584939.1
ITGB4
integrin, beta 4
chr3_+_136676707 0.57 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr20_+_48807351 0.53 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr11_+_65154070 0.52 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr15_+_74466744 0.49 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr3_+_136676851 0.46 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr16_+_8891670 0.43 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr10_-_99185798 0.38 ENST00000439965.2
AL355490.1
LOC644215 protein; Uncharacterized protein
chr10_-_47173994 0.36 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr22_-_20255212 0.35 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr15_+_57891609 0.32 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr17_-_42452063 0.32 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr10_+_47746929 0.32 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr22_+_39966758 0.31 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr2_-_26864228 0.29 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr7_-_100493482 0.29 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr2_-_230135937 0.29 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr8_+_145065521 0.23 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_33256664 0.22 ENST00000444176.1
WDR46
WD repeat domain 46
chr5_+_125758813 0.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr17_-_40835076 0.22 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr5_+_125758865 0.21 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr15_-_74043816 0.21 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr15_+_75498739 0.21 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr10_-_105238997 0.20 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chrX_-_80377162 0.20 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr7_-_100171270 0.20 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr12_-_82752159 0.20 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr17_+_43318434 0.20 ENST00000587489.1
FMNL1
formin-like 1
chr1_-_78444776 0.19 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr8_+_145065705 0.18 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr1_-_78444738 0.18 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr9_+_6758109 0.18 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr3_+_48481658 0.18 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr10_-_97200772 0.18 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr14_-_75078725 0.18 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr15_+_75498355 0.18 ENST00000567617.1
C15orf39
chromosome 15 open reading frame 39
chr15_+_41136369 0.17 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_41136263 0.17 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr14_+_103566665 0.17 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr9_-_128003606 0.17 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr14_+_105935396 0.16 ENST00000494981.1
MTA1
metastasis associated 1
chr19_+_45254529 0.15 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr8_+_54764346 0.15 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr2_+_220283091 0.15 ENST00000373960.3
DES
desmin
chr16_+_67197288 0.15 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr5_+_43120985 0.15 ENST00000515326.1
ZNF131
zinc finger protein 131
chr17_+_37356528 0.14 ENST00000225430.4
RPL19
ribosomal protein L19
chr9_+_6758024 0.14 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr9_+_6757634 0.13 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr16_+_84178874 0.13 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_-_68698222 0.13 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr15_+_64680003 0.13 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr16_-_84178728 0.13 ENST00000562224.1
ENST00000434463.3
ENST00000564998.1
ENST00000219439.4
HSDL1
hydroxysteroid dehydrogenase like 1
chr3_+_100120441 0.12 ENST00000489752.1
LNP1
leukemia NUP98 fusion partner 1
chr17_+_72427477 0.11 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_-_232328867 0.11 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr19_+_49622646 0.11 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_-_25519317 0.10 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_-_52790512 0.10 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr6_+_155538093 0.10 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_-_2883928 0.10 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr8_-_70745575 0.09 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_112194484 0.09 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr8_-_145016692 0.09 ENST00000357649.2
PLEC
plectin
chr7_-_27213893 0.09 ENST00000283921.4
HOXA10
homeobox A10
chr5_+_125759140 0.09 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_+_75032901 0.09 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr18_+_77623668 0.09 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr14_-_25519095 0.09 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_-_49253425 0.09 ENST00000045083.2
FAM65C
family with sequence similarity 65, member C
chr4_+_6717842 0.08 ENST00000320776.3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr2_-_158485387 0.08 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr16_+_84178850 0.08 ENST00000334315.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_+_47137544 0.08 ENST00000564373.1
TEX38
testis expressed 38
chr1_+_156785425 0.07 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr17_-_47492236 0.07 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr2_-_73511559 0.07 ENST00000521871.1
FBXO41
F-box protein 41
chr20_-_52790055 0.07 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr12_-_82752565 0.07 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr1_+_162467595 0.07 ENST00000538489.1
ENST00000489294.1
UHMK1
U2AF homology motif (UHM) kinase 1
chr17_-_79818354 0.07 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr11_-_17035943 0.06 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr1_-_52344471 0.06 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr19_-_35981358 0.06 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr15_+_41136216 0.06 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_-_31833719 0.06 ENST00000524853.1
PAX6
paired box 6
chr18_-_4455260 0.05 ENST00000581527.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr12_+_96196875 0.05 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr2_-_27357479 0.05 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr16_+_222846 0.05 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr19_-_39226045 0.05 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chr1_+_47137445 0.05 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr17_+_37356586 0.05 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr17_-_2615031 0.05 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr7_-_128045984 0.04 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr11_+_236959 0.04 ENST00000431206.2
ENST00000528906.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr17_+_37356555 0.04 ENST00000579374.1
RPL19
ribosomal protein L19
chr19_+_19627026 0.04 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YJEFN3
CTC-260F20.3
NDUFA13
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr17_-_2614927 0.04 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chrX_-_138724994 0.04 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr9_+_87285257 0.04 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr7_-_100493744 0.04 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr9_-_130517309 0.04 ENST00000414380.1
SH2D3C
SH2 domain containing 3C
chr16_+_67195592 0.04 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chr17_-_47492164 0.04 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chrX_-_80377118 0.03 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chrX_-_138724677 0.03 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr1_-_236228403 0.03 ENST00000366595.3
NID1
nidogen 1
chr1_-_68698197 0.03 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr9_+_133223932 0.03 ENST00000420499.2
HMCN2
hemicentin 2
chr2_+_95940220 0.03 ENST00000542147.1
PROM2
prominin 2
chr16_-_14724057 0.03 ENST00000539279.1
ENST00000420015.2
ENST00000437198.2
PARN
poly(A)-specific ribonuclease
chr15_+_41136586 0.03 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_-_1146244 0.03 ENST00000328449.5
C1QTNF8
C1q and tumor necrosis factor related protein 8
chr17_+_78388959 0.02 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr2_-_26205550 0.02 ENST00000405914.1
KIF3C
kinesin family member 3C
chr18_-_53253000 0.02 ENST00000566514.1
TCF4
transcription factor 4
chr9_+_36169380 0.02 ENST00000335119.2
CCIN
calicin
chr1_+_110082487 0.02 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr9_-_132383055 0.02 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr1_-_236228417 0.01 ENST00000264187.6
NID1
nidogen 1
chr6_-_46703069 0.01 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_+_31515337 0.01 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chrX_+_9880590 0.01 ENST00000452575.1
SHROOM2
shroom family member 2
chr12_+_113495492 0.01 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr11_+_66234216 0.01 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr19_-_19626838 0.01 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr18_-_53253323 0.01 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr10_-_105212059 0.01 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr11_-_65686496 0.00 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr1_-_214724566 0.00 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr9_+_138391805 0.00 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr17_-_39023462 0.00 ENST00000251643.4
KRT12
keratin 12

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.7 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC