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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for UCACAGU

Z-value: 1.18

Motif logo

miRNA associated with seed UCACAGU

NamemiRBASE accession
MIMAT0000084
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_179780312 1.10 ENST00000253778.8
glutamine-fructose-6-phosphate transaminase 2
chr15_+_41221536 1.03 ENST00000249749.5
delta-like 4 (Drosophila)
chr16_+_1031762 0.85 ENST00000293894.3
SRY (sex determining region Y)-box 8
chr6_+_19837592 0.79 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_+_155554797 0.74 ENST00000295101.2
potassium inwardly-rectifying channel, subfamily J, member 3
chr5_+_52285144 0.70 ENST00000296585.5
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr4_-_177713788 0.69 ENST00000280193.2
vascular endothelial growth factor C
chr6_+_126112001 0.62 ENST00000392477.2
nuclear receptor coactivator 7
chr1_+_40420802 0.61 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
major facilitator superfamily domain containing 2A
chr19_+_51815102 0.59 ENST00000270642.8
IgLON family member 5
chr9_-_38069208 0.55 ENST00000377707.3
ENST00000377700.4
Src homology 2 domain containing adaptor protein B
chr3_+_51575596 0.55 ENST00000409535.2
RAD54-like 2 (S. cerevisiae)
chr2_+_5832799 0.54 ENST00000322002.3
SRY (sex determining region Y)-box 11
chr19_+_48898132 0.54 ENST00000263269.3
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr5_-_121413974 0.51 ENST00000231004.4
lysyl oxidase
chr12_-_93835665 0.48 ENST00000552442.1
ENST00000550657.1
ubiquitin-conjugating enzyme E2N
chr1_+_205473720 0.48 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr16_-_48644061 0.47 ENST00000262384.3
NEDD4 binding protein 1
chr19_+_1286097 0.46 ENST00000215368.2
ephrin-A2
chr8_+_40010989 0.45 ENST00000315792.3
chromosome 8 open reading frame 4
chr5_-_38595498 0.45 ENST00000263409.4
leukemia inhibitory factor receptor alpha
chr1_+_15736359 0.45 ENST00000375980.4
EF-hand domain family, member D2
chr12_-_26278030 0.44 ENST00000242728.4
basic helix-loop-helix family, member e41
chr1_-_200992827 0.43 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr9_+_137533615 0.42 ENST00000371817.3
collagen, type V, alpha 1
chr14_+_55034599 0.42 ENST00000392067.3
ENST00000357634.3
sterile alpha motif domain containing 4A
chr7_+_116312411 0.41 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chr5_-_157002775 0.41 ENST00000257527.4
ADAM metallopeptidase domain 19
chr21_-_39288743 0.40 ENST00000609713.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr2_-_235405679 0.40 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr17_+_45608430 0.39 ENST00000322157.4
aminopeptidase puromycin sensitive
chr13_+_52158610 0.38 ENST00000298125.5
WD repeat and FYVE domain containing 2
chr15_-_56209306 0.38 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr12_-_54779511 0.38 ENST00000551109.1
ENST00000546970.1
zinc finger protein 385A
chr12_-_54813229 0.37 ENST00000293379.4
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_+_152879985 0.37 ENST00000323534.2
RAP2B, member of RAS oncogene family
chr19_-_46234119 0.37 ENST00000317683.3
F-box protein 46
chr19_+_51152702 0.36 ENST00000425202.1
chromosome 19 open reading frame 81
chr8_-_141645645 0.36 ENST00000519980.1
ENST00000220592.5
argonaute RISC catalytic component 2
chr2_-_200322723 0.35 ENST00000417098.1
SATB homeobox 2
chr7_+_100210133 0.35 ENST00000393950.2
ENST00000424091.2
motile sperm domain containing 3
chr11_-_45687128 0.35 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr16_-_73082274 0.35 ENST00000268489.5
zinc finger homeobox 3
chr9_+_129622904 0.35 ENST00000319119.4
zinc finger and BTB domain containing 34
chr4_+_160188889 0.34 ENST00000264431.4
Rap guanine nucleotide exchange factor (GEF) 2
chr22_+_46067678 0.34 ENST00000381061.4
ENST00000252934.5
ataxin 10
chr2_+_192542850 0.34 ENST00000410026.2
nucleic acid binding protein 1
chr2_-_27718052 0.34 ENST00000264703.3
fibronectin type III domain containing 4
chr5_-_111093406 0.34 ENST00000379671.3
neuronal regeneration related protein
chr6_-_37665751 0.33 ENST00000297153.7
ENST00000434837.3
MAM domain containing glycosylphosphatidylinositol anchor 1
chr12_-_49351303 0.33 ENST00000256682.4
ADP-ribosylation factor 3
chr8_-_127570603 0.33 ENST00000304916.3
family with sequence similarity 84, member B
chr8_-_10588010 0.33 ENST00000304501.1
SRY (sex determining region Y)-box 7
chr1_+_39456895 0.33 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
akirin 1
chr11_-_115375107 0.32 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr2_+_23608064 0.32 ENST00000486442.1
kelch-like family member 29
chr20_-_48770174 0.32 ENST00000341698.2
TMEM189-UBE2V1 readthrough
chr4_-_80994210 0.32 ENST00000403729.2
anthrax toxin receptor 2
chr8_-_41166953 0.31 ENST00000220772.3
secreted frizzled-related protein 1
chr14_+_67999999 0.31 ENST00000329153.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr10_+_8096631 0.31 ENST00000379328.3
GATA binding protein 3
chr1_-_179198702 0.31 ENST00000502732.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_-_222885770 0.30 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr12_+_70760056 0.30 ENST00000258111.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr6_-_99873145 0.30 ENST00000369239.5
ENST00000438806.1
PNN-interacting serine/arginine-rich protein
chr12_-_95611149 0.29 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FYVE, RhoGEF and PH domain containing 6
chr8_-_37756972 0.29 ENST00000330843.4
ENST00000522727.1
ENST00000287263.4
RAB11 family interacting protein 1 (class I)
chr19_-_43969796 0.29 ENST00000244333.3
LY6/PLAUR domain containing 3
chr14_-_61116168 0.29 ENST00000247182.6
SIX homeobox 1
chr19_+_2164126 0.29 ENST00000398665.3
DOT1-like histone H3K79 methyltransferase
chr16_-_12009735 0.28 ENST00000439887.2
ENST00000434724.2
G1 to S phase transition 1
chr8_-_74791051 0.28 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
ubiquitin-conjugating enzyme E2W (putative)
chr1_+_206680879 0.28 ENST00000355294.4
ENST00000367117.3
Ras association (RalGDS/AF-6) domain family member 5
chr2_+_206547215 0.28 ENST00000360409.3
ENST00000540178.1
ENST00000540841.1
ENST00000355117.4
ENST00000450507.1
ENST00000417189.1
neuropilin 2
chr9_-_127905736 0.28 ENST00000336505.6
ENST00000373549.4
suppressor of cancer cell invasion
chr3_-_128212016 0.28 ENST00000498200.1
ENST00000341105.2
GATA binding protein 2
chr5_+_156887027 0.28 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr15_+_64680003 0.28 ENST00000261884.3
thyroid hormone receptor interactor 4
chr8_-_124553437 0.27 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr16_-_4292071 0.27 ENST00000399609.3
sarcalumenin
chr1_-_23886285 0.27 ENST00000374561.5
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_-_31839488 0.27 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr1_+_955448 0.27 ENST00000379370.2
agrin
chrX_+_17393543 0.26 ENST00000380060.3
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr11_+_72929319 0.26 ENST00000393597.2
ENST00000311131.2
purinergic receptor P2Y, G-protein coupled, 2
chr6_+_138188551 0.26 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr5_+_32585605 0.26 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1 homolog (S. cerevisiae)
chr7_+_155250824 0.26 ENST00000297375.4
engrailed homeobox 2
chr2_+_74881355 0.26 ENST00000357877.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr2_-_39348137 0.25 ENST00000426016.1
son of sevenless homolog 1 (Drosophila)
chr3_+_150804676 0.25 ENST00000474524.1
ENST00000273432.4
mediator complex subunit 12-like
chr2_+_7057523 0.25 ENST00000320892.6
ring finger protein 144A
chr22_-_39239987 0.25 ENST00000333039.2
neuronal pentraxin receptor
chr1_+_199996702 0.25 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr3_-_129407535 0.24 ENST00000432054.2
transmembrane and coiled-coil domain family 1
chr19_+_4229495 0.24 ENST00000221847.5
Epstein-Barr virus induced 3
chr10_+_22605304 0.24 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1 readthrough
COMM domain containing 3
chr3_+_14444063 0.24 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
solute carrier family 6 (neurotransmitter transporter), member 6
chr7_-_139876812 0.24 ENST00000397560.2
lysine (K)-specific demethylase 7A
chr20_-_48729670 0.24 ENST00000371657.5
ubiquitin-conjugating enzyme E2 variant 1
chr10_+_64893039 0.24 ENST00000277746.6
ENST00000435510.2
nuclear receptor binding factor 2
chr13_-_79177673 0.23 ENST00000377208.5
POU class 4 homeobox 1
chr20_+_49348081 0.23 ENST00000371610.2
par-6 family cell polarity regulator beta
chr17_-_76713100 0.23 ENST00000585509.1
cytohesin 1
chr4_+_39699664 0.23 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
ubiquitin-conjugating enzyme E2K
chr20_-_48770244 0.23 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
transmembrane protein 189
chr7_-_75368248 0.23 ENST00000434438.2
ENST00000336926.6
huntingtin interacting protein 1
chr20_+_10199468 0.22 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr6_-_24911195 0.22 ENST00000259698.4
family with sequence similarity 65, member B
chr12_+_40787194 0.22 ENST00000425730.2
ENST00000454784.4
mucin 19, oligomeric
chr11_+_120081475 0.22 ENST00000328965.4
OAF homolog (Drosophila)
chr16_+_1756162 0.22 ENST00000250894.4
ENST00000356010.5
mitogen-activated protein kinase 8 interacting protein 3
chr17_-_71228357 0.22 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
family with sequence similarity 104, member A
chr19_-_7293942 0.22 ENST00000341500.5
ENST00000302850.5
insulin receptor
chr18_+_19749386 0.22 ENST00000269216.3
GATA binding protein 6
chr20_+_23342783 0.22 ENST00000544236.1
ENST00000338121.5
ENST00000542987.1
ENST00000424216.1
GDNF-inducible zinc finger protein 1
chr14_+_33408449 0.22 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
neuronal PAS domain protein 3
chr17_+_27717415 0.22 ENST00000583121.1
ENST00000261716.3
TAO kinase 1
chr22_-_37099555 0.21 ENST00000300105.6
calcium channel, voltage-dependent, gamma subunit 2
chrX_-_67653614 0.21 ENST00000355520.5
oligophrenin 1
chr11_+_35684288 0.21 ENST00000299413.5
tripartite motif containing 44
chr3_+_14989076 0.21 ENST00000413118.1
ENST00000425241.1
nuclear receptor subfamily 2, group C, member 2
chr2_+_232260254 0.21 ENST00000287590.5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_+_23037323 0.21 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPH receptor B2
chr6_+_37787262 0.21 ENST00000287218.4
zinc finger, AN1-type domain 3
chr20_+_46130601 0.20 ENST00000341724.6
nuclear receptor coactivator 3
chr17_+_60536002 0.20 ENST00000582809.1
tousled-like kinase 2
chr1_-_57045228 0.20 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr10_-_91403625 0.20 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr13_+_49550015 0.20 ENST00000492622.2
fibronectin type III domain containing 3A
chrX_-_54384425 0.20 ENST00000375169.3
ENST00000354646.2
WNK lysine deficient protein kinase 3
chr8_-_122653630 0.19 ENST00000303924.4
hyaluronan synthase 2
chr8_+_81397876 0.19 ENST00000430430.1
zinc finger and BTB domain containing 10
chr9_-_134145880 0.19 ENST00000372269.3
ENST00000464831.1
family with sequence similarity 78, member A
chr5_-_139726181 0.19 ENST00000507104.1
ENST00000230990.6
heparin-binding EGF-like growth factor
chr1_+_206557366 0.19 ENST00000414007.1
ENST00000419187.2
SLIT-ROBO Rho GTPase activating protein 2
chr22_+_21771656 0.19 ENST00000407464.2
hypermethylated in cancer 2
chr9_+_137218362 0.19 ENST00000481739.1
retinoid X receptor, alpha
chr17_+_38375574 0.19 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WAS/WASL interacting protein family, member 2
chr11_-_1771797 0.19 ENST00000340134.4
interferon induced transmembrane protein 10
chr2_-_9143786 0.19 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr17_+_56833184 0.19 ENST00000308249.2
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr18_-_45456930 0.18 ENST00000262160.6
ENST00000587269.1
SMAD family member 2
chr19_-_6424783 0.18 ENST00000398148.3
KH-type splicing regulatory protein
chr12_-_75905374 0.18 ENST00000438169.2
ENST00000229214.4
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr17_-_80056099 0.18 ENST00000306749.2
fatty acid synthase
chr3_-_124774802 0.18 ENST00000311127.4
heart development protein with EGF-like domains 1
chr16_+_69599861 0.18 ENST00000354436.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_113403434 0.18 ENST00000272542.3
solute carrier family 20 (phosphate transporter), member 1
chr2_+_108443388 0.18 ENST00000354986.4
ENST00000408999.3
RANBP2-like and GRIP domain containing 4
chrX_+_49687216 0.18 ENST00000376088.3
chloride channel, voltage-sensitive 5
chr15_-_41408409 0.18 ENST00000361937.3
INO80 complex subunit
chr16_+_2587998 0.18 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr1_+_76540386 0.18 ENST00000328299.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_8234807 0.18 ENST00000339754.5
NECAP endocytosis associated 1
chr10_-_94003003 0.18 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr5_-_115910630 0.17 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_-_37193606 0.17 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr2_+_238875597 0.17 ENST00000272930.4
ENST00000448502.1
ENST00000416292.1
ENST00000409633.1
ENST00000414443.1
ENST00000409953.1
ENST00000409332.1
ubiquitin-conjugating enzyme E2F (putative)
chr1_+_160370344 0.17 ENST00000368061.2
VANGL planar cell polarity protein 2
chr1_-_47655686 0.17 ENST00000294338.2
PDZK1 interacting protein 1
chr3_-_134093395 0.17 ENST00000249883.5
angiomotin like 2
chr6_+_391739 0.17 ENST00000380956.4
interferon regulatory factor 4
chr15_+_54305101 0.17 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr2_+_46524537 0.17 ENST00000263734.3
endothelial PAS domain protein 1
chr18_-_29522989 0.16 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
trafficking protein particle complex 8
chr19_-_13617247 0.16 ENST00000573710.2
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr13_-_41240717 0.16 ENST00000379561.5
forkhead box O1
chr12_+_50135588 0.16 ENST00000423828.1
ENST00000550445.1
transmembrane BAX inhibitor motif containing 6
chr4_-_7873981 0.16 ENST00000360265.4
actin filament associated protein 1
chrX_-_46618490 0.16 ENST00000328306.4
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr17_+_11924129 0.16 ENST00000353533.5
ENST00000415385.3
mitogen-activated protein kinase kinase 4
chr7_-_5463175 0.16 ENST00000399537.4
ENST00000430969.1
trinucleotide repeat containing 18
chr3_-_53381539 0.16 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
decapping mRNA 1A
chr1_-_78148324 0.16 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr14_+_51706886 0.16 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr19_+_7968728 0.16 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr14_+_50359773 0.16 ENST00000298316.5
ADP-ribosylation factor 6
chr17_-_37557846 0.16 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
F-box and leucine-rich repeat protein 20
chr10_+_112257596 0.15 ENST00000369583.3
dual specificity phosphatase 5
chr21_+_33245548 0.15 ENST00000270112.2
hormonally up-regulated Neu-associated kinase
chr10_-_32636106 0.15 ENST00000263062.8
ENST00000319778.6
enhancer of polycomb homolog 1 (Drosophila)
chr2_-_232645977 0.15 ENST00000409772.1
phosphodiesterase 6D, cGMP-specific, rod, delta
chr12_+_133066137 0.15 ENST00000434748.2
fibrosin-like 1
chr5_+_65440032 0.15 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr3_+_137906109 0.15 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
armadillo repeat containing 8
chr8_-_98290087 0.15 ENST00000322128.3
TSPY-like 5
chr2_+_85132749 0.15 ENST00000233143.4
thymosin beta 10
chr19_-_2721412 0.15 ENST00000323469.4
DIRAS family, GTP-binding RAS-like 1
chr17_-_73389737 0.15 ENST00000392563.1
growth factor receptor-bound protein 2
chr12_-_120687948 0.15 ENST00000458477.2
paxillin
chr17_+_57970469 0.15 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr4_+_52709229 0.15 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCN1, defective in cullin neddylation 1, domain containing 4
chr1_-_95007193 0.14 ENST00000370207.4
ENST00000334047.7
coagulation factor III (thromboplastin, tissue factor)
chr17_-_36831156 0.14 ENST00000325814.5
chromosome 17 open reading frame 96
chr9_-_37576226 0.14 ENST00000432825.2
F-box protein 10
chr8_+_134203273 0.14 ENST00000250160.6
WNT1 inducible signaling pathway protein 1
chr16_-_75467318 0.14 ENST00000283882.3
craniofacial development protein 1
chr5_+_138678131 0.14 ENST00000394795.2
ENST00000510080.1
poly(A) binding protein interacting protein 2
chr10_-_62149433 0.14 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 1.0 GO:0061074 regulation of neural retina development(GO:0061074)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.7 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.3 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.4 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.2 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.2 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.4 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.4 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729) activation of protein kinase C activity(GO:1990051) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.3 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1905033 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.1 GO:0038127 epidermal growth factor receptor signaling pathway(GO:0007173) ERBB signaling pathway(GO:0038127)
0.0 0.1 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0031577 spindle checkpoint(GO:0031577)
0.0 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.6 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.1 GO:0097114 NMDA glutamate receptor clustering(GO:0097114)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.2 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.5 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.1 GO:0060283 trophectodermal cell proliferation(GO:0001834) negative regulation of oocyte development(GO:0060283) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0086015 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.6 GO:0001964 startle response(GO:0001964)
0.0 0.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0021553 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) olfactory nerve development(GO:0021553) semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.4 GO:0021772 olfactory bulb development(GO:0021772)
0.0 0.0 GO:0033563 spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:1904847 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.0 GO:1904796 regulation of core promoter binding(GO:1904796)
0.0 0.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.7 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0031177 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.9 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.0 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951) diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.1 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane