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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for VAX2_RHOXF2

Z-value: 0.21

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
VAX2
ENSG00000116035.2 ventral anterior homeobox 2
RHOXF2
ENSG00000131721.4 Rhox homeobox family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VAX2hg19_v2_chr2_+_71127699_711277440.604.0e-01Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92777606 0.14 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr19_+_11071546 0.11 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr19_-_3557570 0.10 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr12_+_64798826 0.09 ENST00000540203.1
XPOT
exportin, tRNA
chr3_+_157154578 0.08 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_37723336 0.08 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr12_+_26348246 0.08 ENST00000422622.2
SSPN
sarcospan
chr6_-_133035185 0.08 ENST00000367928.4
VNN1
vanin 1
chr6_+_26402517 0.08 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_-_198540751 0.08 ENST00000429081.1
RFTN2
raftlin family member 2
chr6_-_33663474 0.07 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr5_+_66300464 0.07 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr14_+_56584414 0.07 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr3_+_185431080 0.07 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr15_+_80351910 0.06 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr1_-_190446759 0.06 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_-_74618907 0.06 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr1_-_211307404 0.06 ENST00000367007.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chrM_+_3299 0.06 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr2_+_169926047 0.05 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr5_+_174151536 0.05 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr10_+_6821545 0.05 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr2_-_74619152 0.05 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chrX_-_18690210 0.05 ENST00000379984.3
RS1
retinoschisin 1
chrX_-_21676442 0.05 ENST00000379499.2
KLHL34
kelch-like family member 34
chr2_+_149402989 0.05 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr7_+_12726623 0.05 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chr10_+_18549645 0.05 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_66536057 0.05 ENST00000273854.3
EPHA5
EPH receptor A5
chr2_-_74618964 0.05 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr7_+_100860949 0.05 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr7_-_99716952 0.04 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr10_-_17171817 0.04 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr14_+_32798462 0.04 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr9_+_125132803 0.04 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_99717463 0.04 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_+_26402465 0.04 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr1_-_92952433 0.04 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr8_+_92261516 0.04 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr1_+_160370344 0.03 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr4_+_26324474 0.03 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr21_-_37914898 0.03 ENST00000399136.1
CLDN14
claudin 14
chr12_+_31812121 0.03 ENST00000395763.3
METTL20
methyltransferase like 20
chr18_-_67624160 0.03 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr2_+_228736321 0.03 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr1_-_149900122 0.03 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr9_-_16253112 0.03 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr12_-_9760482 0.03 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chrX_+_10126488 0.03 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr9_-_95166841 0.03 ENST00000262551.4
OGN
osteoglycin
chrX_+_36254051 0.03 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr11_-_121986923 0.03 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr7_-_100860851 0.03 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr4_-_74486217 0.02 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_+_26348429 0.02 ENST00000242729.2
SSPN
sarcospan
chr5_-_136649218 0.02 ENST00000510405.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_-_212965104 0.02 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr14_+_103851712 0.02 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr13_-_36050819 0.02 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr1_-_57045228 0.02 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr21_+_17443434 0.02 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chrX_-_77225135 0.02 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr6_+_53883708 0.02 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr3_+_115342349 0.02 ENST00000393780.3
GAP43
growth associated protein 43
chr20_-_50419055 0.02 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr20_-_33735070 0.02 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr10_-_99205607 0.02 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr15_+_49462397 0.02 ENST00000396509.2
GALK2
galactokinase 2
chr13_-_88323514 0.02 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr15_-_98417780 0.02 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr1_+_46972668 0.02 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr14_+_32798547 0.02 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr12_-_6233828 0.02 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr12_-_22063787 0.02 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr11_-_107729887 0.02 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr15_+_58430567 0.02 ENST00000536493.1
AQP9
aquaporin 9
chr15_+_80351977 0.02 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr15_+_58430368 0.02 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr4_-_77328458 0.02 ENST00000388914.3
ENST00000434846.2
CCDC158
coiled-coil domain containing 158
chr12_+_78359999 0.02 ENST00000550503.1
NAV3
neuron navigator 3
chr17_-_41466555 0.02 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chr17_+_66511540 0.02 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_80584903 0.02 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr7_-_99716914 0.02 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr10_+_90660832 0.02 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr4_+_76481258 0.02 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr15_-_49912987 0.02 ENST00000560246.1
ENST00000558594.1
FAM227B
family with sequence similarity 227, member B
chr7_-_99716940 0.02 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_-_95166884 0.01 ENST00000375561.5
OGN
osteoglycin
chr2_-_214016314 0.01 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr16_-_55866997 0.01 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr12_+_131438443 0.01 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr8_-_7243080 0.01 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr15_+_49462434 0.01 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr2_-_198540719 0.01 ENST00000295049.4
RFTN2
raftlin family member 2
chr12_-_10022735 0.01 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr5_-_20575959 0.01 ENST00000507958.1
CDH18
cadherin 18, type 2
chr3_+_186353756 0.01 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr5_+_140557371 0.01 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr6_+_167536230 0.01 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr10_+_6779326 0.01 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr4_+_159727272 0.01 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr1_+_225600404 0.01 ENST00000366845.2
AC092811.1
AC092811.1
chr11_+_33061543 0.01 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chrX_-_70326455 0.01 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr4_+_169418255 0.01 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr5_+_89770696 0.01 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr14_+_67831576 0.01 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr5_-_149829314 0.01 ENST00000407193.1
RPS14
ribosomal protein S14
chr5_-_149829244 0.01 ENST00000312037.5
RPS14
ribosomal protein S14
chr1_+_153747746 0.01 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr4_+_88896819 0.01 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr14_+_74034310 0.01 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr17_+_43238438 0.01 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr18_+_47087055 0.01 ENST00000577628.1
LIPG
lipase, endothelial
chr17_-_39203519 0.01 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr10_-_27529486 0.01 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr1_-_24151903 0.01 ENST00000436439.2
ENST00000374490.3
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr4_+_40201954 0.01 ENST00000511121.1
RHOH
ras homolog family member H
chr17_-_71258491 0.01 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr9_-_3469181 0.01 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr6_-_137494775 0.00 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2
interleukin 22 receptor, alpha 2
chr8_-_1922789 0.00 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr16_-_28608424 0.00 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr14_-_20923195 0.00 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr3_-_112127981 0.00 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr15_+_74218787 0.00 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr20_-_50722183 0.00 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr7_-_44580861 0.00 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr19_+_36632204 0.00 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr6_+_34204642 0.00 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr4_-_66536196 0.00 ENST00000511294.1
EPHA5
EPH receptor A5
chr4_-_159956333 0.00 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr3_-_141747950 0.00 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_-_74486347 0.00 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr19_+_36632485 0.00 ENST00000586963.1
CAPNS1
calpain, small subunit 1
chr12_-_118796971 0.00 ENST00000542902.1
TAOK3
TAO kinase 3
chr4_-_69111401 0.00 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:0044793 negative regulation by host of viral process(GO:0044793) negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.0 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)