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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for VENTX

Z-value: 1.51

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Transcription factors associated with VENTX

Gene Symbol Gene ID Gene Info
VENTX
ENSG00000151650.7 VENT homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_1350509080.891.1e-01Click!

Activity profile of VENTX motif

Sorted Z-values of VENTX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_67968793 1.86 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr4_-_155511887 1.70 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr8_+_107738240 1.36 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr10_-_33405600 1.26 ENST00000414308.1
RP11-342D11.3
RP11-342D11.3
chr13_+_110958124 1.23 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr13_-_67802549 1.09 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr6_+_43968306 1.04 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr5_-_79950775 1.04 ENST00000439211.2
DHFR
dihydrofolate reductase
chr4_+_119200215 1.01 ENST00000602573.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr18_+_29171689 0.96 ENST00000237014.3
TTR
transthyretin
chr5_+_95066823 0.89 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chrX_+_106163626 0.88 ENST00000336803.1
CLDN2
claudin 2
chr17_-_47045949 0.74 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr3_-_57233966 0.72 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr4_+_169418195 0.70 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr12_+_56473939 0.69 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_+_56473910 0.69 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_78470530 0.66 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr4_-_105416039 0.66 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr9_+_2159850 0.65 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_62417957 0.64 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr17_+_68100989 0.61 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_111927449 0.61 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr7_+_139025875 0.60 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr6_-_111927062 0.60 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr17_+_43239191 0.58 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr11_-_111649015 0.57 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr10_+_94594351 0.57 ENST00000371552.4
EXOC6
exocyst complex component 6
chr12_+_107712173 0.56 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr6_+_12290586 0.56 ENST00000379375.5
EDN1
endothelin 1
chr18_-_24237339 0.55 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr17_+_17685422 0.53 ENST00000395774.1
RAI1
retinoic acid induced 1
chr22_+_42834029 0.50 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr17_+_43239231 0.49 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr4_+_129732419 0.49 ENST00000510308.1
PHF17
jade family PHD finger 1
chr7_-_81635106 0.48 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_27764190 0.46 ENST00000537516.1
EOMES
eomesodermin
chr6_-_97731019 0.44 ENST00000275053.4
MMS22L
MMS22-like, DNA repair protein
chr8_+_38831683 0.43 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr4_+_129732467 0.42 ENST00000413543.2
PHF17
jade family PHD finger 1
chr8_+_107738343 0.41 ENST00000521592.1
OXR1
oxidation resistance 1
chr11_-_31531121 0.41 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_-_102591604 0.40 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr17_+_59489112 0.40 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr4_-_84035868 0.38 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chrX_+_55478538 0.37 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr9_+_116225999 0.37 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr14_+_65170820 0.36 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr5_+_60933634 0.36 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr8_+_26150628 0.35 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_-_2113583 0.34 ENST00000397173.4
ENST00000280665.6
DCP1B
decapping mRNA 1B
chr1_+_226411319 0.34 ENST00000542034.1
ENST00000366810.5
MIXL1
Mix paired-like homeobox
chr7_-_107880508 0.33 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr2_-_224467093 0.33 ENST00000305409.2
SCG2
secretogranin II
chrX_-_130423240 0.32 ENST00000370910.1
ENST00000370901.4
IGSF1
immunoglobulin superfamily, member 1
chr14_-_82000140 0.31 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr6_+_130339710 0.30 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr12_-_53994805 0.30 ENST00000328463.7
ATF7
activating transcription factor 7
chr12_-_57328187 0.29 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr14_-_27066636 0.29 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr4_+_37455536 0.29 ENST00000381980.4
ENST00000508175.1
C4orf19
chromosome 4 open reading frame 19
chr2_-_203776864 0.28 ENST00000261015.4
WDR12
WD repeat domain 12
chr18_-_74207146 0.28 ENST00000443185.2
ZNF516
zinc finger protein 516
chr17_+_44701402 0.27 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr16_-_67517716 0.27 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr17_+_68101117 0.26 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_-_161695074 0.26 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_+_43291220 0.26 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chrX_+_123097014 0.25 ENST00000394478.1
STAG2
stromal antigen 2
chr2_-_164592497 0.24 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr2_+_203776937 0.24 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF
calcium responsive transcription factor
chr10_+_74451883 0.23 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr7_-_104909435 0.22 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr12_-_122018346 0.22 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr13_+_76378305 0.22 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr18_+_20714525 0.22 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr17_-_46716647 0.21 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr13_-_26795840 0.20 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr14_+_32798547 0.20 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr17_+_47448102 0.20 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr5_-_142780280 0.19 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_51611477 0.19 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr6_+_101846664 0.19 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
GRIK2
glutamate receptor, ionotropic, kainate 2
chr3_+_130569429 0.18 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr16_-_49890016 0.18 ENST00000563137.2
ZNF423
zinc finger protein 423
chr9_+_136501478 0.17 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr16_+_70207686 0.16 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
CLEC18C
C-type lectin domain family 18, member C
chr1_+_150337144 0.15 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr20_-_50722183 0.15 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr2_-_165698662 0.15 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chrX_-_46187069 0.15 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr6_-_32157947 0.14 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr10_-_13350447 0.13 ENST00000429930.1
AL138764.1
Uncharacterized protein
chr1_+_153746683 0.13 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chrX_+_133733457 0.12 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr7_+_18535346 0.12 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr12_-_94673956 0.12 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr12_-_122017542 0.12 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr11_+_123430948 0.12 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr7_+_148982396 0.11 ENST00000418158.2
ZNF783
zinc finger family member 783
chr7_+_18535321 0.11 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr6_-_76203345 0.11 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr12_-_86650077 0.11 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_-_21977748 0.11 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr2_-_165698521 0.11 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr16_+_69985083 0.11 ENST00000288040.6
ENST00000449317.2
CLEC18A
C-type lectin domain family 18, member A
chr4_+_86749045 0.11 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_61874562 0.11 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr6_+_114178512 0.11 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr4_-_84035905 0.10 ENST00000311507.4
PLAC8
placenta-specific 8
chrX_+_105937068 0.09 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_150337100 0.09 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr11_-_72070206 0.09 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr18_-_53253112 0.09 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr4_+_86525299 0.09 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_65222500 0.09 ENST00000511297.1
ENST00000506030.1
ERBB2IP
erbb2 interacting protein
chr13_-_28545276 0.09 ENST00000381020.7
CDX2
caudal type homeobox 2
chr16_-_74455290 0.09 ENST00000339953.5
CLEC18B
C-type lectin domain family 18, member B
chr8_+_97773202 0.08 ENST00000519484.1
CPQ
carboxypeptidase Q
chr19_-_49622348 0.08 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr6_-_138820624 0.08 ENST00000343505.5
NHSL1
NHS-like 1
chr8_-_109799793 0.08 ENST00000297459.3
TMEM74
transmembrane protein 74
chr12_-_12674032 0.08 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr6_-_139613269 0.07 ENST00000358430.3
TXLNB
taxilin beta
chr9_+_109685630 0.07 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr12_-_120241187 0.07 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr1_-_144994909 0.06 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_-_76203454 0.06 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr11_-_117170403 0.06 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr4_-_122148620 0.06 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr1_+_62439037 0.06 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_+_135596180 0.06 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr11_+_46722368 0.05 ENST00000311764.2
ZNF408
zinc finger protein 408
chr16_-_51185172 0.05 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr17_+_39845134 0.05 ENST00000591776.1
ENST00000469257.1
EIF1
eukaryotic translation initiation factor 1
chr1_+_244515930 0.05 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr18_+_55888767 0.04 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_35198118 0.04 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chrX_-_130423200 0.04 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr4_+_71587669 0.04 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr21_+_39644395 0.03 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_-_62332357 0.03 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_40713573 0.03 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2
chr5_+_43121698 0.03 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131
zinc finger protein 131
chr12_-_101604185 0.03 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr11_+_64018955 0.02 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chrX_-_21676442 0.02 ENST00000379499.2
KLHL34
kelch-like family member 34
chr16_+_69984810 0.02 ENST00000393701.2
ENST00000568461.1
CLEC18A
C-type lectin domain family 18, member A
chr8_-_103425047 0.02 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr4_+_169418255 0.02 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr8_-_103424986 0.02 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr1_-_95391315 0.00 ENST00000545882.1
ENST00000415017.1
CNN3
calponin 3, acidic

Network of associatons between targets according to the STRING database.

First level regulatory network of VENTX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 0.6 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.5 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.9 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035101 FACT complex(GO:0035101)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.5 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine