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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZBTB12

Z-value: 0.50

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Transcription factors associated with ZBTB12

Gene Symbol Gene ID Gene Info
ENSG00000204366.3 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB12hg19_v2_chr6_-_31869769_31869880-0.703.0e-01Click!

Activity profile of ZBTB12 motif

Sorted Z-values of ZBTB12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_158979680 0.80 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr1_+_158979792 0.78 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr1_+_158979686 0.76 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chrX_+_133930798 0.38 ENST00000414371.2
family with sequence similarity 122C
chr7_-_93520191 0.35 ENST00000545378.1
tissue factor pathway inhibitor 2
chr19_-_36019123 0.28 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr11_-_104905840 0.27 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr7_-_93520259 0.27 ENST00000222543.5
tissue factor pathway inhibitor 2
chr6_-_170599561 0.26 ENST00000366756.3
delta-like 1 (Drosophila)
chr11_+_64323156 0.25 ENST00000377585.3
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_-_26033796 0.24 ENST00000259791.2
histone cluster 1, H2ab
chr11_+_64323098 0.23 ENST00000301891.4
solute carrier family 22 (organic anion/urate transporter), member 11
chrX_+_140096761 0.22 ENST00000370530.1
SPANX family, member B1
chr22_+_51039098 0.21 ENST00000399912.1
ENST00000329492.3
ENST00000442429.2
ENST00000341339.4
mitogen-activated protein kinase 8 interacting protein 2
chr11_+_12132117 0.20 ENST00000256194.4
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr11_-_104972158 0.20 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_-_200992827 0.20 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr10_+_90660832 0.19 ENST00000371924.1
STAM binding protein-like 1
chr7_-_3198204 0.19 ENST00000402115.1
ENST00000403226.1
LOC392621; Uncharacterized protein
chr3_-_52097567 0.19 ENST00000541313.1
long intergenic non-protein coding RNA 696
chr22_+_18121356 0.18 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2-like 13 (apoptosis facilitator)
chr12_+_95612006 0.17 ENST00000551311.1
ENST00000546445.1
vezatin, adherens junctions transmembrane protein
chr5_-_176778523 0.16 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
lectin, mannose-binding 2
chr3_-_117716418 0.16 ENST00000484092.1
RP11-384F7.2
chr1_-_32264356 0.15 ENST00000452755.2
SPOC domain containing 1
chr6_+_160693591 0.14 ENST00000419196.1
RP1-276N6.2
chr5_-_176778803 0.13 ENST00000303127.7
lectin, mannose-binding 2
chr18_-_47018769 0.13 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr14_-_62162541 0.13 ENST00000557544.1
HIF1A antisense RNA 1
chr6_+_36097992 0.12 ENST00000211287.4
mitogen-activated protein kinase 13
chrX_-_122866874 0.12 ENST00000245838.8
ENST00000355725.4
THO complex 2
chr11_-_119252359 0.12 ENST00000455332.2
ubiquitin specific peptidase 2
chr5_+_68513557 0.11 ENST00000256441.4
mitochondrial ribosomal protein S36
chr13_-_37633743 0.11 ENST00000497318.1
ENST00000475892.1
ENST00000356185.3
ENST00000350612.6
ENST00000542180.1
ENST00000360252.4
suppressor of Ty 20 homolog (S. cerevisiae)
chr11_-_10920838 0.11 ENST00000503469.2
CTD-2003C8.2
chr20_+_36373032 0.11 ENST00000373473.1
catenin, beta like 1
chr12_-_123565834 0.11 ENST00000546049.1
phosphatidylinositol transfer protein, membrane-associated 2
chr17_-_39677971 0.10 ENST00000393976.2
keratin 15
chr12_-_123459105 0.10 ENST00000543935.1
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr4_+_139694701 0.10 ENST00000502606.1
RP11-98O2.1
chr11_+_65769550 0.10 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
barrier to autointegration factor 1
chr16_-_30134524 0.10 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
mitogen-activated protein kinase 3
chr19_-_54618650 0.10 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr17_+_5981270 0.09 ENST00000571973.1
WSC domain containing 1
chr6_-_114292449 0.09 ENST00000519065.1
histone deacetylase 2
chr1_+_113010056 0.09 ENST00000369686.5
wingless-type MMTV integration site family, member 2B
chr1_+_200993071 0.08 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
chr11_+_65769946 0.08 ENST00000533166.1
barrier to autointegration factor 1
chr12_-_62586543 0.08 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr9_-_4666421 0.08 ENST00000381895.5
spermatogenesis associated 6-like
chr14_+_20187174 0.08 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chr7_-_138347897 0.07 ENST00000288513.5
SVOP-like
chr22_-_42084863 0.07 ENST00000401959.1
ENST00000355257.3
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr8_-_42360015 0.07 ENST00000522707.1
solute carrier family 20 (phosphate transporter), member 2
chr4_+_26859300 0.07 ENST00000494628.2
stromal interaction molecule 2
chr15_-_49912987 0.07 ENST00000560246.1
ENST00000558594.1
family with sequence similarity 227, member B
chr3_-_196242233 0.07 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr6_-_160209471 0.07 ENST00000539948.1
t-complex 1
chr17_-_7142725 0.07 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHD finger protein 23
chr17_-_5487768 0.07 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chr6_-_52926539 0.07 ENST00000350082.5
ENST00000356971.3
intestinal cell (MAK-like) kinase
chr4_+_185734773 0.07 ENST00000508020.1
Uncharacterized protein
chr12_+_72080253 0.06 ENST00000549735.1
transmembrane protein 19
chr17_+_46185111 0.06 ENST00000582104.1
ENST00000584335.1
sorting nexin 11
chr20_-_36793663 0.06 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr8_+_104892639 0.06 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr16_-_30134441 0.06 ENST00000395200.1
mitogen-activated protein kinase 3
chr3_+_185080908 0.06 ENST00000265026.3
mitogen-activated protein kinase kinase kinase 13
chr15_+_81475047 0.06 ENST00000559388.1
interleukin 16
chr6_+_147527103 0.06 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr14_-_91526462 0.06 ENST00000536315.2
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr17_+_36908984 0.06 ENST00000225426.4
ENST00000579088.1
proteasome (prosome, macropain) subunit, beta type, 3
chr19_-_11688500 0.05 ENST00000433365.2
acid phosphatase 5, tartrate resistant
chr13_-_46716969 0.05 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_13248598 0.05 ENST00000337630.6
ENST00000545699.1
germ cell associated 1
chr3_-_157217328 0.05 ENST00000392832.2
ENST00000543418.1
ventricular zone expressed PH domain-containing 1
chr19_+_52264449 0.05 ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr16_-_67969888 0.05 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr3_+_49236910 0.05 ENST00000452691.2
ENST00000366429.2
coiled-coil domain containing 36
chr22_-_50524298 0.05 ENST00000311597.5
megalencephalic leukoencephalopathy with subcortical cysts 1
chrX_+_133371077 0.05 ENST00000517294.1
ENST00000370809.4
coiled-coil domain containing 160
chr20_+_2854066 0.05 ENST00000455631.1
ENST00000216877.6
ENST00000399903.2
ENST00000358719.4
ENST00000431048.1
ENST00000425918.2
ENST00000430705.1
ENST00000318266.5
protein tyrosine phosphatase, receptor type, A
chr11_+_46332679 0.05 ENST00000530518.1
cAMP responsive element binding protein 3-like 1
chr2_+_173600514 0.05 ENST00000264111.6
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_122884553 0.05 ENST00000535290.1
CAP-GLY domain containing linker protein 1
chr10_+_23217006 0.04 ENST00000376528.4
ENST00000447081.1
armadillo repeat containing 3
chrX_-_24690771 0.04 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chrX_-_131353461 0.04 ENST00000370874.1
RAP2C, member of RAS oncogene family
chr5_-_122372354 0.04 ENST00000306442.4
peptidylprolyl isomerase C (cyclophilin C)
chr3_+_101818088 0.04 ENST00000491959.1
zona pellucida-like domain containing 1
chr11_+_63273547 0.04 ENST00000255684.5
ENST00000394618.3
lectin, galactoside-binding, soluble, 12
chr2_-_214013353 0.04 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKAROS family zinc finger 2 (Helios)
chrX_+_101478829 0.04 ENST00000372763.1
ENST00000372758.1
nuclear RNA export factor 2
chr11_-_18063973 0.04 ENST00000528338.1
tryptophan hydroxylase 1
chr17_+_11501748 0.04 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr9_-_28026318 0.04 ENST00000308675.3
leucine rich repeat and Ig domain containing 2
chr3_+_89156799 0.04 ENST00000452448.2
ENST00000494014.1
EPH receptor A3
chrX_+_70338525 0.04 ENST00000374102.1
mediator complex subunit 12
chr10_-_98273668 0.04 ENST00000357947.3
tolloid-like 2
chr1_-_94344754 0.04 ENST00000436063.2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr8_-_102987548 0.04 ENST00000520690.1
neurocalcin delta
chr18_-_57364588 0.03 ENST00000439986.4
collagen and calcium binding EGF domains 1
chr17_-_7518145 0.03 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chr13_+_46039037 0.03 ENST00000349995.5
component of oligomeric golgi complex 3
chr8_-_52721975 0.03 ENST00000356297.4
ENST00000543296.1
peroxidasin homolog (Drosophila)-like
chr6_-_31782813 0.03 ENST00000375654.4
heat shock 70kDa protein 1-like
chr4_-_140477353 0.03 ENST00000406354.1
ENST00000506866.2
SET domain containing (lysine methyltransferase) 7
chr8_+_1993152 0.03 ENST00000262113.4
myomesin 2
chr17_-_61781750 0.03 ENST00000582026.1
STE20-related kinase adaptor alpha
chr1_+_100598742 0.03 ENST00000370139.1
tRNA methyltransferase 13 homolog (S. cerevisiae)
chrX_-_73072534 0.03 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chrX_+_41548259 0.03 ENST00000378138.5
G protein-coupled receptor 34
chr16_+_31724618 0.03 ENST00000530881.1
ENST00000529515.1
zinc finger protein 720
chr11_+_63273811 0.03 ENST00000340246.5
lectin, galactoside-binding, soluble, 12
chr22_-_36236265 0.03 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_22778337 0.03 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr19_-_6767516 0.03 ENST00000245908.6
SH2 domain containing 3A
chr1_+_78956651 0.03 ENST00000370757.3
ENST00000370756.3
prostaglandin F receptor (FP)
chr3_-_151047327 0.02 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr19_+_55417499 0.02 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
natural cytotoxicity triggering receptor 1
chr18_-_53177984 0.02 ENST00000543082.1
transcription factor 4
chr2_+_128405655 0.02 ENST00000423019.1
G protein-coupled receptor 17
chr17_+_7517264 0.02 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
sex hormone-binding globulin
chr11_+_63449045 0.02 ENST00000354497.4
reticulon 3
chr12_-_70004942 0.02 ENST00000361484.3
leucine rich repeat containing 10
chr3_-_164875850 0.02 ENST00000472120.1
RP11-747D18.1
chr15_-_66797172 0.02 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
ribosomal protein L4
chr8_+_1993173 0.02 ENST00000523438.1
myomesin 2
chr4_-_96470108 0.02 ENST00000513796.1
unc-5 homolog C (C. elegans)
chr4_-_140477910 0.02 ENST00000404104.3
SET domain containing (lysine methyltransferase) 7
chr10_+_23216944 0.02 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
armadillo repeat containing 3
chr4_-_168155417 0.02 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_10118348 0.01 ENST00000502702.1
WD repeat domain 1
chr14_+_32476072 0.01 ENST00000556949.1
Uncharacterized protein
chr7_-_27169801 0.01 ENST00000511914.1
homeobox A4
chr4_-_85419603 0.01 ENST00000295886.4
NK6 homeobox 1
chr12_-_56321649 0.01 ENST00000454792.2
ENST00000408946.2
within bgcn homolog (Drosophila)
chr11_-_62323702 0.01 ENST00000530285.1
AHNAK nucleoprotein
chr5_-_35089722 0.01 ENST00000511486.1
ENST00000310101.5
ENST00000231423.3
ENST00000513753.1
ENST00000348262.3
ENST00000397391.3
ENST00000542609.1
prolactin receptor
chr13_+_42712178 0.01 ENST00000536612.1
diacylglycerol kinase, eta
chrX_+_23352133 0.01 ENST00000379361.4
patched domain containing 1
chr9_+_123884038 0.01 ENST00000373847.1
centriolin
chr19_-_6767431 0.01 ENST00000437152.3
ENST00000597687.1
SH2 domain containing 3A
chr2_+_190722119 0.01 ENST00000452382.1
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
chr12_-_11214893 0.01 ENST00000533467.1
taste receptor, type 2, member 46
chr14_+_96949319 0.01 ENST00000554706.1
adenylate kinase 7
chr12_+_49208234 0.01 ENST00000540990.1
calcium channel, voltage-dependent, beta 3 subunit
chr11_+_8704748 0.01 ENST00000526562.1
ENST00000525981.1
ribosomal protein L27a
chr5_+_148443049 0.01 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
chr10_-_54215029 0.01 ENST00000435813.2
RP11-346D6.6
chr8_-_63998590 0.00 ENST00000260116.4
tocopherol (alpha) transfer protein
chr6_+_2988847 0.00 ENST00000380472.3
ENST00000605901.1
ENST00000454015.1
NAD(P)H dehydrogenase, quinone 2
long intergenic non-protein coding RNA 1011
chr19_+_44716678 0.00 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
zinc finger protein 227
chr4_+_184826418 0.00 ENST00000308497.4
ENST00000438269.1
storkhead box 2
chr19_+_58258164 0.00 ENST00000317178.5
zinc finger protein 776
chr5_-_156772729 0.00 ENST00000312349.4
fibronectin type III domain containing 9
chr15_-_55562479 0.00 ENST00000564609.1
RAB27A, member RAS oncogene family
chr4_+_110769258 0.00 ENST00000594814.1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr12_-_56321397 0.00 ENST00000557259.1
ENST00000549939.1
within bgcn homolog (Drosophila)
chr11_-_61124776 0.00 ENST00000542361.1
cytochrome b561 family, member A3
chr1_+_11838988 0.00 ENST00000444493.1
chromosome 1 open reading frame 167
chr4_-_87028478 0.00 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.3 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) positive regulation of skeletal muscle tissue growth(GO:0048633) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 2.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade