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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZBTB3

Z-value: 0.46

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Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ZBTB3
ENSG00000185670.7 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_62521660-0.973.0e-02Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_2626988 0.30 ENST00000509050.1
FAM193A
family with sequence similarity 193, member A
chr5_+_140514782 0.27 ENST00000231134.5
PCDHB5
protocadherin beta 5
chrX_-_154563889 0.20 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr4_-_17783135 0.18 ENST00000265018.3
FAM184B
family with sequence similarity 184, member B
chr16_+_53164956 0.17 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr14_-_92413727 0.16 ENST00000267620.10
FBLN5
fibulin 5
chr19_-_6670128 0.16 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr19_+_39926791 0.16 ENST00000594990.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr10_-_105156198 0.15 ENST00000369815.1
ENST00000309579.3
ENST00000337003.4
USMG5
up-regulated during skeletal muscle growth 5 homolog (mouse)
chr18_+_42260059 0.13 ENST00000426838.4
SETBP1
SET binding protein 1
chr7_+_23719749 0.12 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr8_+_38261880 0.11 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr19_-_19006920 0.11 ENST00000429504.2
ENST00000427170.2
CERS1
ceramide synthase 1
chr17_-_5487768 0.11 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr19_-_45657028 0.11 ENST00000429338.1
ENST00000589776.1
NKPD1
NTPase, KAP family P-loop domain containing 1
chr4_-_140216948 0.10 ENST00000265500.4
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr10_+_99332198 0.10 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr3_+_139063372 0.10 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr12_-_120241187 0.10 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr16_+_87636474 0.10 ENST00000284262.2
JPH3
junctophilin 3
chr9_+_140500126 0.10 ENST00000431925.2
ENST00000419386.1
ARRDC1
arrestin domain containing 1
chr8_+_42196000 0.09 ENST00000518925.1
ENST00000538005.1
POLB
polymerase (DNA directed), beta
chr16_-_2185899 0.09 ENST00000262304.4
ENST00000423118.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr11_-_82782952 0.09 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr5_+_170288856 0.09 ENST00000523189.1
RANBP17
RAN binding protein 17
chr9_+_140500087 0.09 ENST00000371421.4
ARRDC1
arrestin domain containing 1
chr1_+_110036728 0.09 ENST00000369868.3
ENST00000430195.2
CYB561D1
cytochrome b561 family, member D1
chr1_+_211433275 0.08 ENST00000367005.4
RCOR3
REST corepressor 3
chr3_+_139062838 0.08 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
MRPS22
mitochondrial ribosomal protein S22
chr7_+_16793160 0.08 ENST00000262067.4
TSPAN13
tetraspanin 13
chr8_+_144821557 0.08 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr19_-_40023450 0.08 ENST00000326282.4
EID2B
EP300 interacting inhibitor of differentiation 2B
chr9_+_74526532 0.08 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr20_+_62289640 0.07 ENST00000508582.2
ENST00000360203.5
ENST00000356810.4
RTEL1
regulator of telomere elongation helicase 1
chr3_-_53878644 0.07 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr2_+_42396472 0.07 ENST00000318522.5
ENST00000402711.2
EML4
echinoderm microtubule associated protein like 4
chr1_+_110036699 0.07 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
CYB561D1
cytochrome b561 family, member D1
chr9_-_34637718 0.06 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr4_+_48492269 0.06 ENST00000327939.4
ZAR1
zygote arrest 1
chr10_-_118032979 0.06 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr14_-_92413353 0.06 ENST00000556154.1
FBLN5
fibulin 5
chr3_-_149688896 0.06 ENST00000239940.7
PFN2
profilin 2
chr6_+_30851205 0.06 ENST00000515881.1
DDR1
discoidin domain receptor tyrosine kinase 1
chrX_+_134166333 0.06 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chr5_+_74807581 0.06 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr3_-_149688502 0.05 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr9_+_72002837 0.05 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chrX_+_11776278 0.05 ENST00000312196.4
ENST00000337339.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr16_+_30034655 0.05 ENST00000300575.2
C16orf92
chromosome 16 open reading frame 92
chr6_-_31939734 0.05 ENST00000375356.3
DXO
decapping exoribonuclease
chr6_-_31940065 0.05 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr14_-_92414055 0.05 ENST00000342058.4
FBLN5
fibulin 5
chr3_-_149688971 0.05 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr2_-_74570520 0.05 ENST00000394019.2
ENST00000346834.4
ENST00000359484.4
ENST00000423644.1
ENST00000377634.4
ENST00000436454.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr11_-_82782861 0.05 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr19_+_47852538 0.05 ENST00000328771.4
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr21_+_45209394 0.05 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr19_-_19006890 0.04 ENST00000247005.6
GDF1
growth differentiation factor 1
chr19_+_49496705 0.04 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr5_+_76506706 0.04 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr1_+_110036674 0.04 ENST00000393709.3
CYB561D1
cytochrome b561 family, member D1
chr17_-_39623681 0.04 ENST00000225899.3
KRT32
keratin 32
chr16_-_68406161 0.04 ENST00000568373.1
ENST00000563226.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr5_-_76382989 0.04 ENST00000511587.1
ZBED3
zinc finger, BED-type containing 3
chr20_+_54987168 0.04 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr12_+_48577366 0.03 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr5_-_94417314 0.03 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_42396574 0.03 ENST00000401738.3
EML4
echinoderm microtubule associated protein like 4
chr5_+_112074029 0.03 ENST00000512211.2
APC
adenomatous polyposis coli
chr1_-_32801825 0.03 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr5_+_75378997 0.03 ENST00000502798.2
SV2C
synaptic vesicle glycoprotein 2C
chr5_-_94417562 0.03 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_-_236046872 0.03 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr16_+_28986134 0.03 ENST00000352260.7
SPNS1
spinster homolog 1 (Drosophila)
chrX_+_70364667 0.03 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr1_+_160160346 0.03 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr19_+_49496782 0.03 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr2_-_40679186 0.02 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr21_-_48024986 0.02 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr19_+_52848659 0.02 ENST00000327920.8
ZNF610
zinc finger protein 610
chr4_-_5894777 0.02 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr3_-_195163803 0.02 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr6_+_44126545 0.02 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr11_-_130786400 0.02 ENST00000265909.4
SNX19
sorting nexin 19
chr3_-_49131013 0.02 ENST00000424300.1
QRICH1
glutamine-rich 1
chr14_-_90085458 0.02 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3
forkhead box N3
chr15_-_74659978 0.02 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr1_+_210001309 0.02 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr19_+_16187085 0.02 ENST00000300933.4
TPM4
tropomyosin 4
chr7_-_38403077 0.02 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr9_+_125132803 0.01 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_123949053 0.01 ENST00000350887.5
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr17_+_72983674 0.01 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr9_+_74526384 0.01 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr4_+_159236462 0.01 ENST00000460056.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr7_+_100081542 0.01 ENST00000300179.2
ENST00000423930.1
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr12_-_62586543 0.01 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr10_-_76868866 0.01 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr7_-_38394118 0.01 ENST00000390345.2
TRGV4
T cell receptor gamma variable 4
chr1_+_159141397 0.01 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr16_+_28986085 0.01 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr13_+_27998681 0.01 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr18_+_32073253 0.01 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr1_+_154229547 0.01 ENST00000428595.1
UBAP2L
ubiquitin associated protein 2-like
chr11_-_18548426 0.00 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chr3_-_149688655 0.00 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2
profilin 2
chr19_-_49496557 0.00 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr3_+_178276488 0.00 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_46138676 0.00 ENST00000371383.2
ENST00000230565.3
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr1_+_65210772 0.00 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032044 DSIF complex(GO:0032044)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)