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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZNF35

Z-value: 0.49

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Transcription factors associated with ZNF35

Gene Symbol Gene ID Gene Info
ZNF35
ENSG00000169981.6 zinc finger protein 35

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF35hg19_v2_chr3_+_44690211_44690267-0.039.7e-01Click!

Activity profile of ZNF35 motif

Sorted Z-values of ZNF35 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_148939598 0.85 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr4_-_89442940 0.70 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr8_-_95274536 0.42 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr15_+_96876340 0.29 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_61869748 0.28 ENST00000357977.5
NFIA
nuclear factor I/A
chr1_-_161008697 0.28 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr17_-_58042075 0.27 ENST00000305783.8
ENST00000589113.1
ENST00000442346.2
RNFT1
ring finger protein, transmembrane 1
chr13_-_47471155 0.27 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr3_-_148939835 0.24 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr15_+_35270552 0.24 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr8_-_101157680 0.21 ENST00000428847.2
FBXO43
F-box protein 43
chr14_+_76776957 0.21 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr7_-_83824449 0.20 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr15_-_76352069 0.19 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr4_+_129730947 0.19 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr3_-_49967292 0.18 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr5_+_139028510 0.17 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr4_-_99850243 0.15 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E
eukaryotic translation initiation factor 4E
chr5_-_68339648 0.15 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr9_+_42671887 0.15 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr15_+_69857515 0.15 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chrX_+_9431324 0.15 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr21_+_17792672 0.14 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr21_+_35553045 0.14 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr12_-_22487588 0.14 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr2_-_230787879 0.14 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr7_+_27282319 0.13 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr12_+_79258444 0.12 ENST00000261205.4
SYT1
synaptotagmin I
chr21_+_35552978 0.12 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr5_+_72509751 0.11 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr10_-_52645416 0.11 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr6_+_76599809 0.11 ENST00000430435.1
MYO6
myosin VI
chr5_+_139027877 0.09 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr6_-_135271219 0.09 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr17_-_295730 0.09 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr3_-_49066811 0.08 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_+_141106458 0.06 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr10_-_131762105 0.05 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr5_-_39203093 0.05 ENST00000515010.1
FYB
FYN binding protein
chr12_-_22487618 0.05 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr3_+_29323043 0.04 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chrX_-_138724677 0.03 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr14_-_31889782 0.03 ENST00000543095.2
HEATR5A
HEAT repeat containing 5A
chr1_-_243349684 0.02 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr8_+_85095769 0.02 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr17_-_63557759 0.02 ENST00000307078.5
AXIN2
axin 2
chr17_+_75369400 0.02 ENST00000590059.1
SEPT9
septin 9
chr4_+_78804393 0.02 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr18_+_74240610 0.02 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
LINC00908
long intergenic non-protein coding RNA 908
chr12_-_11091862 0.01 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr17_+_39346139 0.01 ENST00000398470.1
ENST00000318329.5
KRTAP9-1
keratin associated protein 9-1
chr17_-_63557309 0.01 ENST00000580513.1
AXIN2
axin 2
chr12_+_54891495 0.01 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr7_+_74072288 0.00 ENST00000443166.1
GTF2I
general transcription factor IIi
chr10_-_75226166 0.00 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr12_+_51318513 0.00 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr8_-_116680833 0.00 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF35

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 1.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters