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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZNF691

Z-value: 0.51

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Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ZNF691
ENSG00000164011.13 zinc finger protein 691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF691hg19_v2_chr1_+_43312258_43312310-0.386.2e-01Click!

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_28199047 1.09 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr1_+_223354486 0.57 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr1_-_935361 0.56 ENST00000484667.2
HES4
hes family bHLH transcription factor 4
chr15_-_40398812 0.41 ENST00000561360.1
BMF
Bcl2 modifying factor
chr10_-_4720301 0.36 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr14_+_55033815 0.29 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr2_+_238475217 0.28 ENST00000165524.1
PRLH
prolactin releasing hormone
chr3_+_183899770 0.28 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_5903714 0.25 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_+_79495397 0.23 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr8_-_123793048 0.23 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr13_-_52703187 0.22 ENST00000355568.4
NEK5
NIMA-related kinase 5
chr10_-_5638048 0.21 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr5_-_39074479 0.20 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RICTOR
RPTOR independent companion of MTOR, complex 2
chr11_-_133826852 0.20 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr8_+_27168988 0.19 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr14_+_55034330 0.19 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr17_-_36760865 0.19 ENST00000584266.1
SRCIN1
SRC kinase signaling inhibitor 1
chr22_-_32058416 0.19 ENST00000439502.2
PISD
phosphatidylserine decarboxylase
chr10_-_4720333 0.18 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr8_+_145294015 0.17 ENST00000544576.1
MROH1
maestro heat-like repeat family member 1
chr4_-_120243545 0.16 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr1_+_39796810 0.16 ENST00000289893.4
MACF1
microtubule-actin crosslinking factor 1
chr16_+_31225337 0.15 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr11_+_102188272 0.15 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr5_+_135170331 0.14 ENST00000425402.1
ENST00000274513.5
ENST00000420621.1
ENST00000433282.2
ENST00000412661.2
SLC25A48
solute carrier family 25, member 48
chr19_+_50380917 0.14 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr1_+_15986364 0.14 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr10_+_4828815 0.14 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr19_+_40877583 0.13 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr17_-_80797886 0.13 ENST00000572562.1
ZNF750
zinc finger protein 750
chrX_+_107069063 0.11 ENST00000262843.6
MID2
midline 2
chr22_-_45608237 0.11 ENST00000492273.1
KIAA0930
KIAA0930
chr3_+_177534653 0.11 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chr15_-_72767490 0.11 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr9_+_139553306 0.11 ENST00000371699.1
EGFL7
EGF-like-domain, multiple 7
chr3_+_44596679 0.11 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
ZKSCAN7
zinc finger with KRAB and SCAN domains 7
chr10_+_104678032 0.10 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chr17_+_30771279 0.10 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chrX_+_153672468 0.10 ENST00000393600.3
FAM50A
family with sequence similarity 50, member A
chr5_-_179107975 0.10 ENST00000376974.4
CBY3
chibby homolog 3 (Drosophila)
chr3_-_194968576 0.09 ENST00000429994.1
XXYLT1
xyloside xylosyltransferase 1
chr8_+_27169138 0.09 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr12_-_109221160 0.09 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr17_+_36908984 0.09 ENST00000225426.4
ENST00000579088.1
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr12_+_27619743 0.09 ENST00000298876.4
ENST00000416383.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr22_-_32058166 0.08 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr19_+_50084561 0.08 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr9_+_71944241 0.08 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr2_-_110371664 0.08 ENST00000545389.1
ENST00000423520.1
SEPT10
septin 10
chr20_-_2644832 0.08 ENST00000380851.5
ENST00000380843.4
IDH3B
isocitrate dehydrogenase 3 (NAD+) beta
chr20_-_33735070 0.07 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr16_-_1821496 0.07 ENST00000564628.1
ENST00000563498.1
NME3
NME/NM23 nucleoside diphosphate kinase 3
chr19_+_55043977 0.07 ENST00000335056.3
KIR3DX1
killer cell immunoglobulin-like receptor, three domains, X1
chr6_+_31553978 0.07 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr11_+_44748361 0.07 ENST00000533202.1
ENST00000533080.1
ENST00000520358.2
ENST00000520999.2
TSPAN18
tetraspanin 18
chr2_+_202098166 0.07 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr3_-_49907323 0.07 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr3_-_167452614 0.07 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr21_-_37852359 0.07 ENST00000399137.1
ENST00000399135.1
CLDN14
claudin 14
chr13_-_52027134 0.07 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr16_+_78133293 0.06 ENST00000566780.1
WWOX
WW domain containing oxidoreductase
chr17_-_61777459 0.06 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr3_-_157251383 0.06 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr19_-_893200 0.06 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr5_+_53686658 0.06 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chrX_-_153775426 0.06 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chrX_+_102469997 0.06 ENST00000372695.5
ENST00000372691.3
BEX4
brain expressed, X-linked 4
chr10_-_61122220 0.06 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr19_-_15560730 0.06 ENST00000389282.4
ENST00000263381.7
WIZ
widely interspaced zinc finger motifs
chr10_-_91011548 0.05 ENST00000456827.1
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr8_-_28347737 0.05 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr2_+_202098203 0.05 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr8_+_32579341 0.05 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr1_-_155232221 0.05 ENST00000355379.3
SCAMP3
secretory carrier membrane protein 3
chr1_-_233431458 0.05 ENST00000258229.9
ENST00000430153.1
PCNXL2
pecanex-like 2 (Drosophila)
chr14_-_106725723 0.05 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr3_-_167452262 0.05 ENST00000487947.2
PDCD10
programmed cell death 10
chr2_+_202125219 0.04 ENST00000323492.7
CASP8
caspase 8, apoptosis-related cysteine peptidase
chrX_+_16188506 0.04 ENST00000329538.5
MAGEB17
melanoma antigen family B, 17
chr7_-_143059780 0.04 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr6_+_31553901 0.04 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr2_-_85788652 0.04 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr11_+_121461097 0.04 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_10605929 0.04 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr4_-_40516560 0.03 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr16_+_810728 0.03 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
MSLN
mesothelin
chr8_+_32579321 0.03 ENST00000522402.1
NRG1
neuregulin 1
chr5_-_42887494 0.03 ENST00000514218.1
SEPP1
selenoprotein P, plasma, 1
chr22_-_43539346 0.03 ENST00000327555.5
ENST00000290429.6
MCAT
malonyl CoA:ACP acyltransferase (mitochondrial)
chr17_-_3417062 0.03 ENST00000570318.1
ENST00000541913.1
SPATA22
spermatogenesis associated 22
chr17_+_73606766 0.03 ENST00000578462.1
MYO15B
myosin XVB pseudogene
chrX_+_107068959 0.02 ENST00000451923.1
MID2
midline 2
chr11_-_71750865 0.02 ENST00000544129.1
NUMA1
nuclear mitotic apparatus protein 1
chr17_+_80416482 0.02 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
NARF
nuclear prelamin A recognition factor
chr2_-_85895295 0.02 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr9_+_116267536 0.02 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr1_-_148202536 0.02 ENST00000544708.1
PPIAL4D
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr12_+_19389814 0.02 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr2_+_68961934 0.02 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr18_+_11751466 0.02 ENST00000535121.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr16_+_23765948 0.02 ENST00000300113.2
CHP2
calcineurin-like EF-hand protein 2
chr1_+_33938236 0.02 ENST00000361328.3
ENST00000373413.2
ZSCAN20
zinc finger and SCAN domain containing 20
chr7_+_7811992 0.02 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr20_-_42816206 0.01 ENST00000372980.3
JPH2
junctophilin 2
chr6_-_27279949 0.01 ENST00000444565.1
ENST00000377451.2
POM121L2
POM121 transmembrane nucleoporin-like 2
chr12_-_51718436 0.01 ENST00000544402.1
BIN2
bridging integrator 2
chr16_+_85687999 0.01 ENST00000412692.1
GSE1
Gse1 coiled-coil protein
chr17_+_80416050 0.01 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF
nuclear prelamin A recognition factor
chr2_+_68961905 0.01 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_38455650 0.01 ENST00000448721.2
SF3A3
splicing factor 3a, subunit 3, 60kDa
chr17_+_37026106 0.01 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chrX_+_153775821 0.01 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr4_+_48492269 0.01 ENST00000327939.4
ZAR1
zygote arrest 1
chr4_-_16077741 0.01 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr8_+_144821557 0.01 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr6_+_31021225 0.01 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr3_+_37493610 0.01 ENST00000264741.5
ITGA9
integrin, alpha 9
chr19_+_40873617 0.01 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr12_+_120502441 0.01 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr14_+_60712463 0.01 ENST00000325642.3
ENST00000529574.1
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr16_-_11492366 0.01 ENST00000595360.1
CTD-3088G3.8
Protein LOC388210
chr20_-_2489542 0.00 ENST00000421216.1
ENST00000381253.1
ZNF343
zinc finger protein 343
chr17_+_20978854 0.00 ENST00000456235.1
AC087393.1
AC087393.1
chr17_+_37026284 0.00 ENST00000433206.2
ENST00000435347.3
LASP1
LIM and SH3 protein 1
chr15_+_84904525 0.00 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr4_+_657485 0.00 ENST00000471824.2
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_-_51717948 0.00 ENST00000267012.4
BIN2
bridging integrator 2
chr9_+_138453595 0.00 ENST00000479141.1
ENST00000371766.2
ENST00000277508.5
ENST00000433563.1
PAEP
progestagen-associated endometrial protein

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.3 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation