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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AAUCUCU

Z-value: 0.25

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miRNA associated with seed AAUCUCU

NamemiRBASE accession
hsa-miR-216b-5p
MIMAT0004959

Activity profile of AAUCUCU motif

Sorted Z-values of AAUCUCU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_48920960 0.17 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr7_+_35840542 0.12 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr2_+_48010221 0.10 ENST00000234420.5
MSH6
mutS homolog 6
chr4_-_105416039 0.10 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr13_-_31038370 0.10 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr10_-_104474128 0.10 ENST00000260746.5
ARL3
ADP-ribosylation factor-like 3
chr16_-_46723066 0.08 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr10_-_120101804 0.08 ENST00000369183.4
ENST00000369172.4
FAM204A
family with sequence similarity 204, member A
chr8_+_76452097 0.07 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr3_-_113465065 0.07 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr9_-_20622478 0.06 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr14_+_57735614 0.06 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr4_+_99916765 0.06 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr12_+_111471828 0.05 ENST00000261726.6
CUX2
cut-like homeobox 2
chr16_+_67678818 0.05 ENST00000334583.6
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr15_-_100258029 0.04 ENST00000378904.2
DKFZP779J2370
DKFZP779J2370
chr14_+_62037287 0.02 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr17_+_30677136 0.02 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
ZNF207
zinc finger protein 207
chr11_+_60739140 0.01 ENST00000313421.7
CD6
CD6 molecule
chr1_+_107683644 0.01 ENST00000370067.1
NTNG1
netrin G1
chr7_+_21467642 0.01 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr15_+_73344791 0.00 ENST00000261908.6
NEO1
neogenin 1
chr7_+_12250886 0.00 ENST00000444443.1
ENST00000396667.3
TMEM106B
transmembrane protein 106B
chr18_+_59854480 0.00 ENST00000256858.6
ENST00000398130.2
KIAA1468
KIAA1468

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1903181 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)