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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ATF5

Z-value: 0.78

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.4 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg19_v2_chr19_+_50431959_50431998-0.493.2e-01Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_32546145 1.03 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr14_+_32546274 0.70 ENST00000396582.2
Rho GTPase activating protein 5
chr1_+_223354486 0.57 ENST00000446145.1
RP11-239E10.3
chr6_-_100016492 0.54 ENST00000369217.4
ENST00000369220.4
ENST00000482541.2
cyclin C
chr1_+_206137237 0.48 ENST00000468509.1
ENST00000367129.2
family with sequence similarity 72, member A
chr1_+_16083098 0.47 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr21_-_35773370 0.47 ENST00000410005.1
chromosome 21 open reading frame 140
chr2_-_113542063 0.47 ENST00000263339.3
interleukin 1, alpha
chr6_-_100016678 0.45 ENST00000523799.1
ENST00000520429.1
cyclin C
chr11_+_28724129 0.42 ENST00000513853.1
RP11-115J23.1
chr1_+_101361626 0.41 ENST00000370112.4
solute carrier family 30 (zinc transporter), member 7
chr8_+_95732095 0.40 ENST00000414645.2
dpy-19-like 4 (C. elegans)
chr14_+_32547434 0.39 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr1_+_101361782 0.37 ENST00000357650.4
solute carrier family 30 (zinc transporter), member 7
chr18_-_24283586 0.37 ENST00000579458.1
Small nucleolar RNA U3
chr6_+_87865262 0.37 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr2_-_188419078 0.36 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chrX_+_123095546 0.36 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
stromal antigen 2
chr6_-_100016527 0.36 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
cyclin C
chr1_+_209859510 0.36 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr3_-_88108192 0.35 ENST00000309534.6
CGG triplet repeat binding protein 1
chr2_-_87248975 0.35 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr5_-_39219705 0.35 ENST00000351578.6
FYN binding protein
chr12_-_100656134 0.34 ENST00000548313.1
DEP domain containing 4
chr8_+_95731904 0.34 ENST00000522422.1
dpy-19-like 4 (C. elegans)
chr3_-_101232019 0.32 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr3_-_182698381 0.32 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr16_-_72128270 0.31 ENST00000426362.2
thioredoxin-like 4B
chr17_+_38334501 0.30 ENST00000541245.1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_-_188419200 0.30 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr22_+_37678505 0.30 ENST00000402997.1
ENST00000405206.3
cytohesin 4
chr1_+_151739131 0.30 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr8_+_107738240 0.30 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr15_+_63481668 0.29 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr1_+_61869748 0.29 ENST00000357977.5
nuclear factor I/A
chr9_-_125240235 0.29 ENST00000259357.2
olfactory receptor, family 1, subfamily J, member 1
chr14_-_65569244 0.28 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr4_+_84377115 0.28 ENST00000295491.4
ENST00000507019.1
mitochondrial ribosomal protein S18C
chr22_-_30662828 0.26 ENST00000403463.1
ENST00000215781.2
oncostatin M
chrX_-_122866874 0.26 ENST00000245838.8
ENST00000355725.4
THO complex 2
chr6_+_31865552 0.25 ENST00000469372.1
ENST00000497706.1
complement component 2
chr5_+_175223715 0.25 ENST00000515502.1
complexin 2
chr19_-_8642289 0.25 ENST00000596675.1
ENST00000338257.8
myosin IF
chr11_-_117102768 0.25 ENST00000532301.1
proprotein convertase subtilisin/kexin type 7
chr16_+_9185450 0.25 ENST00000327827.7
chromosome 16 open reading frame 72
chr12_-_120884175 0.24 ENST00000546954.1
TP53 regulated inhibitor of apoptosis 1
chr17_-_7108436 0.24 ENST00000493294.1
discs, large homolog 4 (Drosophila)
chr7_-_3083573 0.23 ENST00000396946.4
caspase recruitment domain family, member 11
chr14_+_50065376 0.23 ENST00000298288.6
leucine rich repeat protein 1
chr8_-_131028869 0.23 ENST00000518283.1
ENST00000519110.1
family with sequence similarity 49, member B
chrX_+_123095155 0.23 ENST00000371160.1
ENST00000435103.1
stromal antigen 2
chr7_-_37488547 0.23 ENST00000453399.1
engulfment and cell motility 1
chr12_-_54778244 0.22 ENST00000549937.1
zinc finger protein 385A
chr12_-_72057638 0.22 ENST00000552037.1
ENST00000378743.3
zinc finger, C3H1-type containing
chr14_+_96968802 0.22 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr2_-_113999260 0.21 ENST00000468980.2
paired box 8
chrX_+_131157609 0.21 ENST00000496850.1
Serine/threonine-protein kinase MST4
chr11_-_7904464 0.21 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
chr3_-_23958506 0.21 ENST00000425478.2
NFKB inhibitor interacting Ras-like 1
chr14_+_21566980 0.21 ENST00000418511.2
ENST00000554329.2
transmembrane protein 253
chr9_+_131902346 0.21 ENST00000432124.1
ENST00000435305.1
protein phosphatase 2A activator, regulatory subunit 4
chr4_+_84377198 0.20 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
mitochondrial ribosomal protein S18C
chr14_+_96968707 0.20 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
poly(A) polymerase alpha
chr18_-_812517 0.20 ENST00000584307.1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr19_+_4229495 0.20 ENST00000221847.5
Epstein-Barr virus induced 3
chr9_+_19230433 0.20 ENST00000434457.2
ENST00000602925.1
DENN/MADD domain containing 4C
chr4_-_84376953 0.20 ENST00000510985.1
ENST00000295488.3
helicase, POLQ-like
chr5_-_39219641 0.20 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr3_-_69129501 0.20 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr2_+_234601512 0.19 ENST00000305139.6
UDP glucuronosyltransferase 1 family, polypeptide A6
chrX_-_47489244 0.18 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
complement factor properdin
chr14_+_100111447 0.18 ENST00000330710.5
ENST00000357223.2
HHIP-like 1
chr8_+_107738343 0.18 ENST00000521592.1
oxidation resistance 1
chrX_-_44402231 0.18 ENST00000378045.4
FUN14 domain containing 1
chr1_-_103574024 0.18 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
collagen, type XI, alpha 1
chr3_+_19988885 0.18 ENST00000422242.1
RAB5A, member RAS oncogene family
chrX_+_123095890 0.17 ENST00000435215.1
stromal antigen 2
chr5_-_148442584 0.16 ENST00000394358.2
ENST00000512049.1
SH3 domain and tetratricopeptide repeats 2
chr19_+_15160130 0.16 ENST00000427043.3
caspase 14, apoptosis-related cysteine peptidase
chr17_+_7533439 0.16 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
sex hormone-binding globulin
chr3_-_23958402 0.16 ENST00000415901.2
ENST00000416026.2
ENST00000412028.1
ENST00000388759.3
ENST00000437230.1
NFKB inhibitor interacting Ras-like 1
chr17_+_33474826 0.15 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
unc-45 homolog B (C. elegans)
chr2_-_209118974 0.15 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
isocitrate dehydrogenase 1 (NADP+), soluble
chrX_-_19983260 0.14 ENST00000340625.3
chromosome X open reading frame 23
chr1_-_27286897 0.14 ENST00000320567.5
chromosome 1 open reading frame 172
chr14_-_65569186 0.14 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MYC associated factor X
chr4_+_42399856 0.14 ENST00000319234.4
shisa family member 3
chr19_+_41509851 0.14 ENST00000593831.1
ENST00000330446.5
cytochrome P450, family 2, subfamily B, polypeptide 6
chr3_-_114173530 0.13 ENST00000470311.1
zinc finger and BTB domain containing 20
chrX_+_133930798 0.13 ENST00000414371.2
family with sequence similarity 122C
chr12_-_96336369 0.13 ENST00000546947.1
ENST00000546386.1
coiled-coil domain containing 38
chr1_+_202091980 0.13 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr3_-_183145873 0.13 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF.2 cell line derived transforming sequence-like 2
chr12_+_32655048 0.13 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr11_-_104480019 0.13 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr18_-_812231 0.12 ENST00000314574.4
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr6_-_31514333 0.12 ENST00000376151.4
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr12_-_12491608 0.12 ENST00000545735.1
MANSC domain containing 1
chr11_+_57310114 0.12 ENST00000527972.1
ENST00000399154.2
smoothelin-like 1
chr1_+_211433275 0.12 ENST00000367005.4
REST corepressor 3
chr14_+_50065459 0.12 ENST00000318317.4
leucine rich repeat protein 1
chr8_-_21645804 0.12 ENST00000518077.1
ENST00000517892.1
GDNF family receptor alpha 2
chr17_-_6947225 0.11 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr3_+_19988566 0.11 ENST00000273047.4
RAB5A, member RAS oncogene family
chr12_+_32655110 0.11 ENST00000546442.1
ENST00000583694.1
FYVE, RhoGEF and PH domain containing 4
chr8_-_100025238 0.11 ENST00000521696.1
RP11-410L14.2
chr5_-_148442687 0.11 ENST00000515425.1
SH3 domain and tetratricopeptide repeats 2
chr5_+_148786518 0.11 ENST00000518014.1
ENST00000505340.1
ENST00000509909.1
AC131025.8
MIR143 host gene (non-protein coding)
chr5_-_132200477 0.11 ENST00000296875.2
growth differentiation factor 9
chr3_-_88108212 0.11 ENST00000482016.1
CGG triplet repeat binding protein 1
chr14_+_79746249 0.10 ENST00000428277.2
neurexin 3
chr2_+_153191706 0.10 ENST00000288670.9
formin-like 2
chr12_+_10124001 0.10 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
C-type lectin domain family 12, member A
chr6_+_76599809 0.10 ENST00000430435.1
myosin VI
chr17_+_33474860 0.10 ENST00000394570.2
unc-45 homolog B (C. elegans)
chr5_-_20575959 0.10 ENST00000507958.1
cadherin 18, type 2
chr17_+_33914424 0.10 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr19_-_18366182 0.10 ENST00000355502.3
phosphodiesterase 4C, cAMP-specific
chr12_-_1920886 0.09 ENST00000536846.2
ENST00000538027.2
ENST00000538450.1
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr21_-_28215332 0.09 ENST00000517777.1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_+_23958470 0.09 ENST00000434031.2
ENST00000413699.1
ENST00000456530.2
ribosomal protein L15
chr5_+_82767487 0.09 ENST00000343200.5
ENST00000342785.4
versican
chr2_-_225434538 0.09 ENST00000409096.1
cullin 3
chr3_-_187454281 0.09 ENST00000232014.4
B-cell CLL/lymphoma 6
chr2_-_145278475 0.09 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr1_+_3607228 0.08 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
tumor protein p73
chr5_+_154393260 0.08 ENST00000435029.4
kinesin family member 4B
chr7_-_78400598 0.08 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_208994548 0.08 ENST00000282141.3
crystallin, gamma C
chr5_+_50678921 0.08 ENST00000230658.7
ISL LIM homeobox 1
chr1_-_47697387 0.08 ENST00000371884.2
T-cell acute lymphocytic leukemia 1
chr7_-_127672146 0.08 ENST00000476782.1
leucine rich repeat containing 4
chr2_-_121624973 0.08 ENST00000603720.1
RP11-297J22.1
chrX_+_123095860 0.08 ENST00000428941.1
stromal antigen 2
chr3_+_190105909 0.08 ENST00000456423.1
claudin 16
chr5_-_180552304 0.08 ENST00000329365.2
olfactory receptor, family 2, subfamily V, member 1
chr7_+_150688166 0.08 ENST00000461406.1
nitric oxide synthase 3 (endothelial cell)
chr12_-_16761117 0.08 ENST00000538051.1
LIM domain only 3 (rhombotin-like 2)
chr4_+_2800722 0.07 ENST00000508385.1
SH3-domain binding protein 2
chr3_+_112930387 0.07 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr2_-_197036289 0.07 ENST00000263955.4
serine/threonine kinase 17b
chrX_+_130677950 0.07 ENST00000338616.3
olfactory receptor, family 13, subfamily H, member 1
chr4_-_68620053 0.07 ENST00000420975.2
ENST00000226413.4
gonadotropin-releasing hormone receptor
chr5_+_132009675 0.07 ENST00000231449.2
ENST00000350025.2
interleukin 4
chr15_-_90222642 0.07 ENST00000430628.2
perilipin 1
chr8_+_67344710 0.07 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
alcohol dehydrogenase, iron containing, 1
chr17_+_47287749 0.07 ENST00000419580.2
ABI family, member 3
chr2_-_87018784 0.07 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr4_+_48807155 0.06 ENST00000504654.1
OCIA domain containing 1
chr9_-_6007787 0.06 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
chr8_-_21646290 0.06 ENST00000519195.1
GDNF family receptor alpha 2
chr19_+_55795493 0.06 ENST00000309383.1
BR serine/threonine kinase 1
chr19_-_7936344 0.06 ENST00000599142.1
Protein FLJ22184
chrX_+_153409678 0.06 ENST00000369951.4
opsin 1 (cone pigments), long-wave-sensitive
chr13_-_36871886 0.06 ENST00000491049.2
ENST00000503173.1
ENST00000239860.6
ENST00000379862.2
ENST00000239859.7
ENST00000379864.2
ENST00000510088.1
ENST00000554962.1
ENST00000511166.1
coiled-coil domain containing 169
spermatogenesis and oogenesis specific basic helix-loop-helix 2
CCDC169-SOHLH2 readthrough
chr16_-_72206034 0.05 ENST00000537465.1
ENST00000237353.10
polyamine modulated factor 1 binding protein 1
chr2_+_149447783 0.05 ENST00000449013.1
enhancer of polycomb homolog 2 (Drosophila)
chr18_-_53089538 0.05 ENST00000566777.1
transcription factor 4
chr5_+_82767583 0.05 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
versican
chr1_-_17304771 0.05 ENST00000375534.3
microfibrillar-associated protein 2
chr1_-_22109484 0.05 ENST00000529637.1
ubiquitin specific peptidase 48
chr9_+_2621798 0.05 ENST00000382100.3
very low density lipoprotein receptor
chr5_+_82767284 0.05 ENST00000265077.3
versican
chr1_-_22109682 0.05 ENST00000400301.1
ENST00000532737.1
ubiquitin specific peptidase 48
chr7_+_143771275 0.05 ENST00000408898.2
olfactory receptor, family 2, subfamily A, member 25
chr10_+_111765562 0.05 ENST00000360162.3
adducin 3 (gamma)
chr5_+_138629417 0.05 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr1_-_183387723 0.04 ENST00000287713.6
nicotinamide nucleotide adenylyltransferase 2
chr15_+_75118888 0.04 ENST00000395018.4
complexin 3
chr11_-_106889250 0.04 ENST00000526355.2
guanylate cyclase 1, soluble, alpha 2
chr16_-_65155979 0.04 ENST00000562325.1
ENST00000268603.4
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_+_28943260 0.04 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19 molecule
chr14_-_65569057 0.04 ENST00000555419.1
ENST00000341653.2
MYC associated factor X
chr22_-_37215523 0.04 ENST00000216200.5
parvalbumin
chr18_-_53089723 0.04 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr5_+_110559603 0.04 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr3_+_23958632 0.04 ENST00000412097.1
ENST00000415719.1
ENST00000435882.1
ribosomal protein L15
chr10_+_103113840 0.04 ENST00000393441.4
ENST00000408038.2
beta-transducin repeat containing E3 ubiquitin protein ligase
chr17_+_44668387 0.04 ENST00000576040.1
N-ethylmaleimide-sensitive factor
chrX_+_122318006 0.04 ENST00000371266.1
ENST00000264357.5
glutamate receptor, ionotropic, AMPA 3
chr3_-_183145765 0.04 ENST00000473233.1
MCF.2 cell line derived transforming sequence-like 2
chr7_+_128399002 0.04 ENST00000493278.1
calumenin
chr16_+_22103828 0.04 ENST00000567131.1
ENST00000568328.1
ENST00000389398.5
ENST00000389397.4
von Willebrand factor A domain containing 3A
chr1_+_48688357 0.04 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr9_+_2621950 0.03 ENST00000382096.1
very low density lipoprotein receptor
chr19_-_38916822 0.03 ENST00000586305.1
RAS guanyl releasing protein 4
chr5_+_50679506 0.03 ENST00000511384.1
ISL LIM homeobox 1
chr7_-_27142290 0.03 ENST00000222718.5
homeobox A2
chr1_+_16083123 0.03 ENST00000510393.1
ENST00000430076.1
filamin binding LIM protein 1
chr8_-_95449155 0.03 ENST00000481490.2
fibrinogen silencer binding protein
chr2_+_88047606 0.03 ENST00000359481.4
plasminogen-like B2
chr4_-_175750364 0.03 ENST00000340217.5
ENST00000274093.3
glycine receptor, alpha 3
chr3_-_62861012 0.03 ENST00000357948.3
ENST00000383710.4
Ca++-dependent secretion activator
chr3_-_114173654 0.03 ENST00000482689.1
zinc finger and BTB domain containing 20
chr7_-_78400364 0.03 ENST00000535697.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_79745746 0.03 ENST00000281127.7
neurexin 3
chr16_-_65155833 0.03 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr14_+_92789498 0.03 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_-_95220775 0.03 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr2_-_209119831 0.02 ENST00000345146.2
isocitrate dehydrogenase 1 (NADP+), soluble

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.7 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.2 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.1 GO:0014806 smooth muscle hyperplasia(GO:0014806)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.1 GO:0071288 B cell costimulation(GO:0031296) cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0042738 exogenous drug catabolic process(GO:0042738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement