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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BATF3

Z-value: 0.36

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Transcription factors associated with BATF3

Gene Symbol Gene ID Gene Info
BATF3
ENSG00000123685.4 basic leucine zipper ATF-like transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATF3hg19_v2_chr1_-_212873267_2128733320.029.7e-01Click!

Activity profile of BATF3 motif

Sorted Z-values of BATF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_76829258 0.33 ENST00000588600.1
ATP9B
ATPase, class II, type 9B
chr8_-_67090825 0.14 ENST00000276571.3
CRH
corticotropin releasing hormone
chr17_+_29421900 0.12 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr9_-_3489406 0.12 ENST00000457373.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr14_-_24732368 0.11 ENST00000544573.1
TGM1
transglutaminase 1
chrX_-_135056106 0.11 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr3_+_184056614 0.10 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr19_-_49622348 0.10 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr17_+_29421987 0.09 ENST00000431387.4
NF1
neurofibromin 1
chr1_+_228353495 0.08 ENST00000366711.3
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr14_+_68086515 0.08 ENST00000261783.3
ARG2
arginase 2
chr3_-_52312337 0.07 ENST00000469000.1
WDR82
WD repeat domain 82
chr17_-_49124230 0.07 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr14_+_20811766 0.06 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr15_+_34394257 0.06 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr2_-_65659762 0.06 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr22_+_37959647 0.06 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr7_-_93633658 0.05 ENST00000433727.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr6_-_106773491 0.05 ENST00000360666.4
ATG5
autophagy related 5
chr5_-_175965008 0.05 ENST00000537487.1
RNF44
ring finger protein 44
chr16_+_58535372 0.04 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr8_+_37594185 0.04 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2
ER lipid raft associated 2
chr2_-_43823093 0.04 ENST00000405006.4
THADA
thyroid adenoma associated
chr3_-_119182506 0.04 ENST00000468676.1
TMEM39A
transmembrane protein 39A
chr11_+_28129795 0.04 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr18_+_76829441 0.04 ENST00000458297.2
ATP9B
ATPase, class II, type 9B
chr3_-_119182523 0.04 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr3_-_119182453 0.04 ENST00000491685.1
ENST00000461654.1
TMEM39A
transmembrane protein 39A
chr2_-_43823119 0.04 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr4_-_39367949 0.04 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr10_+_123923105 0.03 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr14_+_20811722 0.03 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr6_-_106773291 0.03 ENST00000343245.3
ATG5
autophagy related 5
chr11_-_28129656 0.03 ENST00000263181.6
KIF18A
kinesin family member 18A
chr2_-_202645835 0.03 ENST00000264276.6
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr6_-_106773610 0.03 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chrX_-_135056216 0.03 ENST00000305963.2
MMGT1
membrane magnesium transporter 1
chr4_+_170581213 0.03 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr5_+_112849373 0.03 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr16_+_68057153 0.03 ENST00000358896.6
ENST00000568099.2
DUS2
dihydrouridine synthase 2
chr12_-_92539614 0.02 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr2_+_220071490 0.02 ENST00000409206.1
ENST00000409594.1
ENST00000289528.5
ENST00000422255.1
ENST00000409412.1
ENST00000409097.1
ENST00000409336.1
ENST00000409217.1
ENST00000409319.1
ENST00000444522.2
ZFAND2B
zinc finger, AN1-type domain 2B
chr9_-_100684769 0.02 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr10_+_123923205 0.02 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr1_+_156030937 0.02 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr11_+_12695944 0.02 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr18_+_76829385 0.02 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr22_+_31518938 0.02 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_+_70142232 0.02 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr8_+_37594130 0.02 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr16_+_68056844 0.02 ENST00000565263.1
DUS2
dihydrouridine synthase 2
chr2_-_25194963 0.02 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr2_-_65357225 0.02 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A
RAB1A, member RAS oncogene family
chr20_+_42219559 0.02 ENST00000373030.3
ENST00000373039.4
IFT52
intraflagellar transport 52 homolog (Chlamydomonas)
chr12_-_123380610 0.01 ENST00000535765.1
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr4_-_2010562 0.01 ENST00000411649.1
ENST00000542778.1
ENST00000411638.2
ENST00000431323.1
NELFA
negative elongation factor complex member A
chr12_+_10365082 0.01 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr9_-_99381660 0.01 ENST00000375240.3
ENST00000463569.1
CDC14B
cell division cycle 14B
chr2_+_70142189 0.01 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr10_+_123922941 0.01 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr12_+_10365404 0.01 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_-_47616992 0.01 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr19_+_8455200 0.01 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr19_+_8455077 0.01 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr19_+_47616682 0.01 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr2_+_74757050 0.01 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr7_+_100464760 0.01 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr16_+_68057179 0.01 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr14_-_24732403 0.01 ENST00000206765.6
TGM1
transglutaminase 1
chr3_+_38206975 0.01 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr6_-_31939734 0.01 ENST00000375356.3
DXO
decapping exoribonuclease
chr19_+_18723660 0.01 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr14_-_77495007 0.01 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr3_+_128598433 0.01 ENST00000308982.7
ENST00000514336.1
ACAD9
acyl-CoA dehydrogenase family, member 9
chrX_+_48398053 0.01 ENST00000537536.1
ENST00000418627.1
TBC1D25
TBC1 domain family, member 25
chr11_-_85376121 0.01 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr3_-_101405539 0.01 ENST00000469605.1
ENST00000495401.1
ENST00000394077.3
RPL24
ribosomal protein L24
chr4_-_104119488 0.01 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr1_+_153750622 0.00 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr1_+_151682909 0.00 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) cellular response to cocaine(GO:0071314) positive regulation of fear response(GO:1903367) regulation of corticosterone secretion(GO:2000852) positive regulation of behavioral fear response(GO:2000987)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)