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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CDC5L

Z-value: 1.50

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
ENSG00000096401.7 cell division cycle 5 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_443553150.805.4e-02Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91152303 5.41 ENST00000371804.3
interferon-induced protein with tetratricopeptide repeats 1
chr4_+_155484155 1.32 ENST00000509493.1
fibrinogen beta chain
chr3_-_122283424 1.19 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr15_-_42076229 1.19 ENST00000597767.1
Uncharacterized protein
chr4_+_155484103 1.16 ENST00000302068.4
fibrinogen beta chain
chr22_-_40929812 0.95 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr2_+_228678550 0.90 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr4_+_80584903 0.87 ENST00000506460.1
RP11-452C8.1
chr1_+_196621002 0.86 ENST00000367429.4
ENST00000439155.2
complement factor H
chr18_+_61442629 0.83 ENST00000398019.2
ENST00000540675.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr10_-_69597828 0.75 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr21_+_37692481 0.74 ENST00000400485.1
MORC family CW-type zinc finger 3
chr1_+_158985457 0.74 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr5_-_133510456 0.73 ENST00000520417.1
S-phase kinase-associated protein 1
chr4_+_74606223 0.72 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr10_-_69597810 0.71 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr2_+_200472779 0.70 ENST00000427045.1
ENST00000419243.1
AC093590.1
chrX_-_11129229 0.69 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
chr1_-_154600421 0.68 ENST00000368471.3
ENST00000292205.5
adenosine deaminase, RNA-specific
chr5_-_157161727 0.67 ENST00000599823.1
Uncharacterized protein
chr19_-_54567159 0.64 ENST00000338372.2
ENST00000376626.1
V-set and transmembrane domain containing 1
chr2_-_203103185 0.64 ENST00000409205.1
small ubiquitin-like modifier 1
chr2_-_113542063 0.63 ENST00000263339.3
interleukin 1, alpha
chr13_+_78315528 0.61 ENST00000496045.1
SLAIN motif family, member 1
chr18_+_20494078 0.61 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr3_+_107364769 0.61 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
bobby sox homolog (Drosophila)
chr7_-_102985288 0.59 ENST00000379263.3
DnaJ (Hsp40) homolog, subfamily C, member 2
chr13_-_86373536 0.58 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr1_+_196621156 0.58 ENST00000359637.2
complement factor H
chr6_-_76072719 0.57 ENST00000370020.1
filamin A interacting protein 1
chr10_-_69597915 0.57 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr18_+_61445007 0.56 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_+_108321623 0.55 ENST00000497905.1
ENST00000463306.1
DAZ interacting zinc finger protein 3
chr17_+_68164752 0.53 ENST00000535240.1
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_+_127140956 0.53 ENST00000608214.1
RP11-480C22.1
chr9_-_73029540 0.52 ENST00000377126.2
Kruppel-like factor 9
chr4_+_164265035 0.51 ENST00000338566.3
neuropeptide Y receptor Y5
chr20_+_52824367 0.50 ENST00000371419.2
prefoldin subunit 4
chr11_-_102651343 0.49 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr3_+_57882061 0.49 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr1_-_89591749 0.47 ENST00000370466.3
guanylate binding protein 2, interferon-inducible
chr3_+_107364683 0.47 ENST00000413213.1
bobby sox homolog (Drosophila)
chr9_+_35673853 0.47 ENST00000378357.4
carbonic anhydrase IX
chr8_+_107593198 0.46 ENST00000517686.1
oxidation resistance 1
chr13_-_31038370 0.46 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr19_+_51897742 0.46 ENST00000600765.1
CTD-2616J11.14
chr2_+_238877424 0.46 ENST00000434655.1
ubiquitin-conjugating enzyme E2F (putative)
chr14_-_54425475 0.45 ENST00000559642.1
bone morphogenetic protein 4
chr12_-_53601055 0.45 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr10_+_126630692 0.45 ENST00000359653.4
zinc finger, RAN-binding domain containing 1
chr14_+_104029362 0.43 ENST00000495778.1
apoptogenic 1, mitochondrial
chr10_+_27793257 0.43 ENST00000375802.3
RAB18, member RAS oncogene family
chr2_-_180871780 0.43 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_93645314 0.42 ENST00000343253.7
coiled-coil domain containing 18
chr3_+_122044084 0.42 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr11_-_85430088 0.42 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr14_+_56127960 0.42 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr4_+_119200215 0.42 ENST00000602573.1
small nucleolar RNA host gene 8 (non-protein coding)
chr14_+_56127989 0.42 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr1_+_78470530 0.41 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_-_74233480 0.41 ENST00000455918.1
eukaryotic translation elongation factor 1 alpha 1
chr12_-_49463620 0.40 ENST00000550675.1
Ras homolog enriched in brain like 1
chr1_-_247094628 0.39 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AT hook containing transcription factor 1
chr21_+_35107346 0.39 ENST00000456489.1
intersectin 1 (SH3 domain protein)
chr21_+_17214724 0.38 ENST00000449491.1
ubiquitin specific peptidase 25
chr6_+_64345698 0.38 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHD finger protein 3
chr7_+_33945132 0.38 ENST00000436222.1
BMP binding endothelial regulator
chrM_+_12331 0.38 ENST00000361567.2
mitochondrially encoded NADH dehydrogenase 5
chr11_-_62609281 0.38 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr12_+_79439405 0.37 ENST00000552744.1
synaptotagmin I
chr10_+_111765562 0.37 ENST00000360162.3
adducin 3 (gamma)
chr19_+_37178482 0.37 ENST00000536254.2
zinc finger protein 567
chr21_+_33784670 0.37 ENST00000300255.2
eva-1 homolog C (C. elegans)
chr4_+_130017268 0.36 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr5_-_135290651 0.36 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr10_-_62493223 0.36 ENST00000373827.2
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_150039877 0.36 ENST00000419023.1
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr12_+_27398584 0.36 ENST00000543246.1
serine/threonine kinase 38 like
chr18_-_37380230 0.35 ENST00000591629.1
long intergenic non-protein coding RNA 669
chr2_+_86116396 0.35 ENST00000455121.3
AC105053.4
chr2_+_210444748 0.35 ENST00000392194.1
microtubule-associated protein 2
chr6_+_26156551 0.35 ENST00000304218.3
histone cluster 1, H1e
chr22_+_29168652 0.35 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr4_-_76912070 0.35 ENST00000395711.4
ENST00000356260.5
SDA1 domain containing 1
chr13_+_78315348 0.34 ENST00000441784.1
SLAIN motif family, member 1
chr13_+_76378305 0.33 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr3_-_107596910 0.33 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr2_+_86333340 0.33 ENST00000409783.2
ENST00000409277.3
pentatricopeptide repeat domain 3
chr17_+_15604513 0.33 ENST00000481540.1
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr2_+_196521845 0.33 ENST00000359634.5
ENST00000412905.1
solute carrier family 39 (zinc transporter), member 10
chr3_+_57881966 0.33 ENST00000495364.1
sarcolemma associated protein
chr7_+_128399002 0.33 ENST00000493278.1
calumenin
chr2_+_210518057 0.33 ENST00000452717.1
microtubule-associated protein 2
chr1_+_70820451 0.33 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HERV-H LTR-associating 3
chrX_-_45629661 0.32 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr6_+_76330355 0.32 ENST00000483859.2
SUMO1/sentrin specific peptidase 6
chr1_+_179335101 0.32 ENST00000508285.1
ENST00000511889.1
axonemal dynein light chain domain containing 1
chr2_-_203103281 0.32 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
small ubiquitin-like modifier 1
chr1_+_156308403 0.31 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSSK6 activating co-chaperone
chr4_-_185395191 0.31 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr3_-_64009658 0.31 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr15_+_49715449 0.31 ENST00000560979.1
fibroblast growth factor 7
chr4_-_57253587 0.31 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
aminoadipate-semialdehyde dehydrogenase
chr5_+_68860949 0.31 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr3_+_25824405 0.30 ENST00000452098.1
3-oxoacyl-ACP synthase, mitochondrial
chr1_-_209741018 0.30 ENST00000424696.2
RP1-272L16.1
chr2_+_132479948 0.30 ENST00000355171.4
chromosome 2 open reading frame 27A
chr3_+_151531859 0.30 ENST00000488869.1
arylacetamide deacetylase
chr1_-_150738261 0.30 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr12_-_57030096 0.30 ENST00000549506.1
bromodomain adjacent to zinc finger domain, 2A
chr7_-_102985035 0.29 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr6_-_56492816 0.29 ENST00000522360.1
dystonin
chr14_-_38036271 0.29 ENST00000556024.1
RP11-356O9.2
chr5_-_43557791 0.29 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr5_+_179135246 0.29 ENST00000508787.1
calnexin
chr14_-_53331239 0.29 ENST00000553663.1
fermitin family member 2
chr18_-_28682374 0.29 ENST00000280904.6
desmocollin 2
chr8_-_124279627 0.28 ENST00000357082.4
ZHX1-C8ORF76 readthrough
chr1_-_65468148 0.28 ENST00000415842.1
RP11-182I10.3
chr19_+_21324863 0.28 ENST00000598331.1
zinc finger protein 431
chr14_-_31856397 0.28 ENST00000538864.2
ENST00000550366.1
HEAT repeat containing 5A
chr12_+_28605426 0.27 ENST00000542801.1
coiled-coil domain containing 91
chr1_+_244515930 0.27 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr11_-_31014214 0.27 ENST00000406071.2
ENST00000339794.5
doublecortin domain containing 1
chr11_+_73661364 0.27 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr8_+_104311059 0.27 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
frizzled family receptor 6
chrX_+_23925918 0.27 ENST00000379211.3
chromosome X open reading frame 58
chr5_-_95018660 0.26 ENST00000395899.3
ENST00000274432.8
spermatogenesis associated 9
chr15_-_55562451 0.26 ENST00000568803.1
RAB27A, member RAS oncogene family
chr15_+_65823092 0.26 ENST00000566074.1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_57882024 0.26 ENST00000494088.1
sarcolemma associated protein
chr12_+_1099675 0.26 ENST00000545318.2
ELKS/RAB6-interacting/CAST family member 1
chr2_+_33683109 0.26 ENST00000437184.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_44550441 0.26 ENST00000420756.1
ENST00000444696.1
prolyl endopeptidase-like
chr2_+_234601512 0.26 ENST00000305139.6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr16_+_21623392 0.26 ENST00000562961.1
methyltransferase like 9
chr5_+_43033818 0.26 ENST00000607830.1
CTD-2035E11.4
chr3_+_20081515 0.26 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr3_-_149051444 0.26 ENST00000296059.2
transmembrane 4 L six family member 18
chr3_-_176914238 0.26 ENST00000430069.1
ENST00000428970.1
transducin (beta)-like 1 X-linked receptor 1
chr2_+_118572226 0.26 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_177545563 0.26 ENST00000434309.1
RP11-91K9.1
chr8_-_110988070 0.26 ENST00000524391.1
potassium channel, subfamily V, member 1
chr10_+_35484053 0.26 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
cAMP responsive element modulator
chr2_-_37544209 0.26 ENST00000234179.2
protein kinase D3
chr16_-_69418553 0.25 ENST00000569542.2
telomeric repeat binding factor 2
chr2_+_44001172 0.25 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr19_+_852291 0.25 ENST00000263621.1
elastase, neutrophil expressed
chr9_+_40028620 0.25 ENST00000426179.1
AL353791.1
chr5_+_33440802 0.25 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr2_-_191399073 0.25 ENST00000421038.1
transmembrane protein 194B
chr12_+_19593515 0.25 ENST00000360995.4
AE binding protein 2
chr1_-_6260896 0.25 ENST00000497965.1
ribosomal protein L22
chr5_-_98262240 0.25 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr4_+_170541678 0.25 ENST00000360642.3
ENST00000512813.1
chloride channel, voltage-sensitive 3
chr12_-_76817036 0.25 ENST00000546946.1
oxysterol binding protein-like 8
chr7_+_77469439 0.24 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr1_+_198189921 0.24 ENST00000391974.3
NIMA-related kinase 7
chr6_-_149969829 0.24 ENST00000367411.2
katanin p60 (ATPase containing) subunit A 1
chr12_-_54653313 0.24 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr2_+_183582774 0.24 ENST00000537515.1
DnaJ (Hsp40) homolog, subfamily C, member 10
chr10_+_27793197 0.24 ENST00000356940.6
ENST00000535776.1
RAB18, member RAS oncogene family
chr1_+_150039787 0.24 ENST00000535106.1
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr3_+_184534994 0.24 ENST00000441141.1
ENST00000445089.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr11_-_85430163 0.24 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr4_+_78804393 0.23 ENST00000502384.1
mitochondrial ribosomal protein L1
chr5_+_121297650 0.23 ENST00000339397.4
serum response factor binding protein 1
chr6_+_126221034 0.23 ENST00000433571.1
nuclear receptor coactivator 7
chr18_-_10701979 0.23 ENST00000538948.1
ENST00000285141.4
piezo-type mechanosensitive ion channel component 2
chr6_-_149969871 0.23 ENST00000335643.8
ENST00000444282.1
katanin p60 (ATPase containing) subunit A 1
chr22_+_44761431 0.23 ENST00000406912.1
Uncharacterized protein
chr1_+_156338993 0.23 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
Rh family, B glycoprotein (gene/pseudogene)
chr9_-_20382446 0.23 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_57182400 0.23 ENST00000607273.1
primase, DNA, polypeptide 2 (58kDa)
chr1_+_63249796 0.23 ENST00000443289.1
ENST00000317868.4
ENST00000371120.3
autophagy related 4C, cysteine peptidase
chrX_-_15683147 0.23 ENST00000380342.3
transmembrane protein 27
chr14_-_60636561 0.23 ENST00000536410.2
ENST00000216500.5
dehydrogenase/reductase (SDR family) member 7
chr4_+_119809984 0.23 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr11_+_57308979 0.23 ENST00000457912.1
smoothelin-like 1
chr8_+_92082424 0.22 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr20_+_16710606 0.22 ENST00000377943.5
ENST00000246071.6
small nuclear ribonucleoprotein polypeptide B
chr6_+_27791862 0.22 ENST00000355057.1
histone cluster 1, H4j
chr5_-_148929848 0.22 ENST00000504676.1
ENST00000515435.1
casein kinase 1, alpha 1
chr4_+_48833015 0.22 ENST00000509122.1
ENST00000509664.1
ENST00000505922.2
ENST00000514981.1
OCIA domain containing 1
chr16_-_69419473 0.22 ENST00000566750.1
telomeric repeat binding factor 2
chr8_+_95731904 0.22 ENST00000522422.1
dpy-19-like 4 (C. elegans)
chr13_+_50589390 0.22 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr4_-_141348999 0.22 ENST00000325617.5
calmegin
chr3_-_176914191 0.22 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
transducin (beta)-like 1 X-linked receptor 1
chr2_+_210517895 0.22 ENST00000447185.1
microtubule-associated protein 2
chr1_+_66458072 0.22 ENST00000423207.2
phosphodiesterase 4B, cAMP-specific
chr2_+_70121075 0.21 ENST00000409116.1
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr8_-_62602327 0.21 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr2_+_196521903 0.21 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr16_-_3422283 0.21 ENST00000399974.3
MT-RNR2-like 4
chr6_+_121756809 0.21 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr4_-_159094194 0.21 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr18_-_11148587 0.21 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
piezo-type mechanosensitive ion channel component 2
chr10_+_69865866 0.21 ENST00000354393.2
myopalladin
chr6_+_136172820 0.21 ENST00000308191.6
phosphodiesterase 7B

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.0 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.3 0.9 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 0.7 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 2.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.9 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.6 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 0.6 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.5 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 1.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.5 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0072097 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.8 GO:2000391 regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:2000987 cell communication by chemical coupling(GO:0010643) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:2001280 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.5 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.2 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0042245 RNA repair(GO:0042245)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.8 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.1 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:1903598 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) positive regulation of gap junction assembly(GO:1903598) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 2.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.0 5.7 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.0 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 2.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 6.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC