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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DPRX

Z-value: 1.34

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Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
DPRX
ENSG00000204595.1 divergent-paired related homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DPRXhg19_v2_chr19_+_54135310_54135310-0.582.2e-01Click!

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_321340 10.59 ENST00000526811.1
IFITM3
interferon induced transmembrane protein 3
chr11_-_321050 5.09 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr12_+_113344755 1.19 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344582 1.12 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_66796401 0.73 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_+_89299885 0.73 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr12_+_113344811 0.67 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_6949964 0.64 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr1_-_150208320 0.59 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_63461642 0.56 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr22_-_38480100 0.51 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr5_-_77072145 0.45 ENST00000380377.4
TBCA
tubulin folding cofactor A
chr20_+_10199566 0.45 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr4_-_153700864 0.44 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr12_+_104359641 0.42 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr18_-_28681950 0.41 ENST00000251081.6
DSC2
desmocollin 2
chr12_+_113416265 0.40 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr4_-_87374330 0.38 ENST00000511328.1
ENST00000503911.1
MAPK10
mitogen-activated protein kinase 10
chr2_-_235405168 0.37 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr17_-_65992544 0.37 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr12_+_104359614 0.36 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr8_+_104384616 0.36 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr3_-_54962100 0.35 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr5_-_54988448 0.33 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr1_-_68516393 0.33 ENST00000395201.1
DIRAS3
DIRAS family, GTP-binding RAS-like 3
chr4_-_147443043 0.33 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr15_+_42565464 0.32 ENST00000562170.1
ENST00000562859.1
GANC
glucosidase, alpha; neutral C
chr5_-_77072085 0.32 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chr1_+_63989004 0.31 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr18_-_28682374 0.31 ENST00000280904.6
DSC2
desmocollin 2
chr20_-_36794938 0.30 ENST00000453095.1
TGM2
transglutaminase 2
chr2_-_119605253 0.29 ENST00000295206.6
EN1
engrailed homeobox 1
chr8_+_107630340 0.29 ENST00000497705.1
OXR1
oxidation resistance 1
chr7_+_89975979 0.29 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10
GTP-binding protein 10 (putative)
chr1_-_209741018 0.29 ENST00000424696.2
RP1-272L16.1
RP1-272L16.1
chr6_+_7107999 0.28 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr16_+_30386098 0.27 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr12_-_104359475 0.27 ENST00000553183.1
C12orf73
chromosome 12 open reading frame 73
chr17_-_26127525 0.27 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chrX_+_53449887 0.27 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr15_-_42565221 0.26 ENST00000563371.1
ENST00000568400.1
ENST00000568432.1
TMEM87A
transmembrane protein 87A
chr3_+_111630451 0.26 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr6_+_130339710 0.26 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr10_+_70661014 0.26 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr17_+_48351785 0.25 ENST00000507382.1
TMEM92
transmembrane protein 92
chr10_+_104178946 0.25 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr8_+_35649365 0.25 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr5_-_59064458 0.25 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_110937351 0.25 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_+_35856951 0.25 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr5_+_138678131 0.25 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr1_+_207262881 0.25 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr18_-_32957260 0.24 ENST00000587422.1
ENST00000306346.1
ENST00000589332.1
ENST00000586687.1
ENST00000585522.1
ZNF396
zinc finger protein 396
chr1_-_149400542 0.24 ENST00000392948.2
HIST2H3PS2
histone cluster 2, H3, pseudogene 2
chr7_-_37488547 0.24 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr20_-_36794902 0.24 ENST00000373403.3
TGM2
transglutaminase 2
chr5_-_180235755 0.24 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_+_104359576 0.24 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr11_-_85430088 0.23 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr3_+_10068095 0.23 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr2_+_103378472 0.22 ENST00000412401.2
TMEM182
transmembrane protein 182
chr7_+_73868220 0.22 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chr3_+_37035289 0.22 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr5_+_94955782 0.21 ENST00000380007.2
GPR150
G protein-coupled receptor 150
chr6_-_84418432 0.21 ENST00000519825.1
ENST00000523484.2
SNAP91
synaptosomal-associated protein, 91kDa
chr1_-_150780757 0.21 ENST00000271651.3
CTSK
cathepsin K
chr11_-_85430204 0.21 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr2_+_232063436 0.21 ENST00000440107.1
ARMC9
armadillo repeat containing 9
chr6_-_37225391 0.21 ENST00000356757.2
TMEM217
transmembrane protein 217
chr6_-_37225367 0.21 ENST00000336655.2
TMEM217
transmembrane protein 217
chr2_+_7118755 0.20 ENST00000433456.1
RNF144A
ring finger protein 144A
chr20_-_34330129 0.20 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr1_+_15986364 0.20 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr7_-_75401513 0.19 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr20_-_43936937 0.19 ENST00000342716.4
ENST00000353917.5
ENST00000360607.6
ENST00000372751.4
MATN4
matrilin 4
chr11_-_8816375 0.19 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr2_+_27799389 0.19 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr4_+_84377198 0.19 ENST00000507349.1
ENST00000509970.1
ENST00000505719.1
MRPS18C
mitochondrial ribosomal protein S18C
chr2_+_120517174 0.19 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr5_+_118604439 0.18 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr9_-_123812542 0.18 ENST00000223642.1
C5
complement component 5
chr14_+_59951161 0.18 ENST00000261247.9
ENST00000425728.2
ENST00000556985.1
ENST00000554271.1
ENST00000554795.1
JKAMP
JNK1/MAPK8-associated membrane protein
chr12_-_56105880 0.18 ENST00000557257.1
ITGA7
integrin, alpha 7
chrX_-_15683147 0.18 ENST00000380342.3
TMEM27
transmembrane protein 27
chr1_+_81771806 0.18 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr3_-_158390282 0.18 ENST00000264265.3
LXN
latexin
chr5_+_132083106 0.18 ENST00000378731.1
CCNI2
cyclin I family, member 2
chr8_-_65730127 0.17 ENST00000522106.1
RP11-1D12.2
RP11-1D12.2
chr7_+_94536898 0.17 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr5_-_124081008 0.17 ENST00000306315.5
ZNF608
zinc finger protein 608
chr3_-_15469045 0.17 ENST00000450816.2
METTL6
methyltransferase like 6
chr17_-_5323480 0.17 ENST00000573584.1
NUP88
nucleoporin 88kDa
chr7_-_30066233 0.17 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr15_-_42565606 0.17 ENST00000307216.6
ENST00000448392.1
TMEM87A
transmembrane protein 87A
chr5_+_138677515 0.17 ENST00000265192.4
ENST00000511706.1
PAIP2
poly(A) binding protein interacting protein 2
chr5_+_118604385 0.17 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_63481668 0.16 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr4_+_170541835 0.16 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr21_-_38362497 0.16 ENST00000427746.1
ENST00000336648.4
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr4_+_159131596 0.16 ENST00000512481.1
TMEM144
transmembrane protein 144
chr11_-_118436606 0.16 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_+_35220613 0.16 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr19_+_36157715 0.16 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr1_-_152086556 0.16 ENST00000368804.1
TCHH
trichohyalin
chr3_+_130650738 0.16 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_7108210 0.16 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr1_+_207262170 0.15 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr14_-_50319482 0.15 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr10_+_74451883 0.15 ENST00000373053.3
ENST00000357157.6
MCU
mitochondrial calcium uniporter
chr2_+_120517717 0.14 ENST00000420482.1
ENST00000488279.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr11_-_61849656 0.14 ENST00000524942.1
RP11-810P12.5
RP11-810P12.5
chr20_+_22034809 0.14 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr14_-_50319758 0.14 ENST00000298310.5
NEMF
nuclear export mediator factor
chr12_+_133033703 0.14 ENST00000542627.1
RP11-503G7.1
RP11-503G7.1
chr4_-_147442817 0.14 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr12_+_130554803 0.14 ENST00000535487.1
RP11-474D1.2
RP11-474D1.2
chr10_-_103578182 0.14 ENST00000439817.1
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr3_+_23847432 0.14 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr11_-_111944704 0.14 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr3_+_141105705 0.14 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr11_-_85430163 0.13 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr4_+_159131630 0.13 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chrX_-_133931164 0.13 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr9_+_35792151 0.13 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr3_+_101659682 0.13 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr14_+_75469606 0.13 ENST00000266126.5
EIF2B2
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr1_+_36772691 0.12 ENST00000312808.4
ENST00000505871.1
SH3D21
SH3 domain containing 21
chr11_-_118436707 0.12 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr3_+_148447887 0.12 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chrX_+_53449839 0.12 ENST00000457095.1
RIBC1
RIB43A domain with coiled-coils 1
chr8_-_53626974 0.12 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr7_+_73868439 0.12 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr3_+_133502877 0.12 ENST00000466490.2
SRPRB
signal recognition particle receptor, B subunit
chr1_+_179561011 0.12 ENST00000294848.8
ENST00000444136.1
TDRD5
tudor domain containing 5
chr7_+_135242652 0.12 ENST00000285968.6
ENST00000440390.2
NUP205
nucleoporin 205kDa
chr5_-_159846066 0.12 ENST00000519349.1
ENST00000520664.1
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr1_+_162351503 0.12 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr19_+_50528971 0.12 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473
zinc finger protein 473
chr1_-_36615065 0.12 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr2_+_114737146 0.12 ENST00000412690.1
AC010982.1
AC010982.1
chr11_-_104905840 0.12 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr6_+_43215727 0.12 ENST00000304139.5
TTBK1
tau tubulin kinase 1
chr11_+_107879459 0.12 ENST00000393094.2
CUL5
cullin 5
chr4_-_103998439 0.12 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr17_-_7080227 0.11 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr3_+_37035263 0.11 ENST00000458205.2
ENST00000539477.1
MLH1
mutL homolog 1
chr10_-_89577910 0.11 ENST00000308448.7
ENST00000541004.1
ATAD1
ATPase family, AAA domain containing 1
chr12_-_95010147 0.11 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr1_-_184943610 0.11 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr17_+_7482785 0.11 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr7_-_99573677 0.11 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr20_+_33759854 0.11 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr3_+_52448539 0.11 ENST00000461861.1
PHF7
PHD finger protein 7
chr14_+_70918874 0.11 ENST00000603540.1
ADAM21
ADAM metallopeptidase domain 21
chr1_-_115301235 0.11 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr6_+_31554826 0.11 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr6_-_32784687 0.11 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr4_-_87279641 0.11 ENST00000512689.1
MAPK10
mitogen-activated protein kinase 10
chr9_+_17135016 0.11 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chrX_-_77150911 0.10 ENST00000373336.3
MAGT1
magnesium transporter 1
chr6_-_32908765 0.10 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr8_-_117886955 0.10 ENST00000297338.2
RAD21
RAD21 homolog (S. pombe)
chr1_+_29063119 0.10 ENST00000474884.1
ENST00000542507.1
YTHDF2
YTH domain family, member 2
chr7_+_134576317 0.10 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr1_+_182808474 0.10 ENST00000367549.3
DHX9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr3_+_188664988 0.10 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr17_-_37557846 0.10 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr4_-_122791583 0.10 ENST00000506636.1
ENST00000264499.4
BBS7
Bardet-Biedl syndrome 7
chr3_+_49058444 0.10 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_+_97483366 0.10 ENST00000463745.1
ENST00000462412.1
ARL6
ADP-ribosylation factor-like 6
chr11_-_111944895 0.10 ENST00000431456.1
ENST00000280350.4
ENST00000530641.1
PIH1D2
PIH1 domain containing 2
chr4_-_170924888 0.10 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr15_+_42565393 0.10 ENST00000561871.1
GANC
glucosidase, alpha; neutral C
chr1_-_153521714 0.10 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr4_-_16077741 0.09 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr14_-_22005062 0.09 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr12_+_58138664 0.09 ENST00000257910.3
TSPAN31
tetraspanin 31
chr6_-_84418738 0.09 ENST00000519779.1
SNAP91
synaptosomal-associated protein, 91kDa
chr4_-_103998060 0.09 ENST00000339611.4
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr14_-_94789663 0.09 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr1_-_151965048 0.09 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr11_+_63448918 0.09 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chr6_-_35480640 0.09 ENST00000428978.1
ENST00000322263.4
TULP1
tubby like protein 1
chr2_-_85555355 0.08 ENST00000282120.2
ENST00000398263.2
TGOLN2
trans-golgi network protein 2
chr2_-_68290106 0.08 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
C1D
C1D nuclear receptor corepressor
chr6_-_35480705 0.08 ENST00000229771.6
TULP1
tubby like protein 1
chr6_+_31555045 0.08 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr9_+_17134980 0.08 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr11_+_2323349 0.08 ENST00000381121.3
TSPAN32
tetraspanin 32
chr10_-_103578162 0.08 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr11_+_108094786 0.08 ENST00000601453.1
ATM
ataxia telangiectasia mutated
chr1_-_65533390 0.08 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr2_-_85555385 0.08 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr6_+_42018614 0.08 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr7_+_134464376 0.08 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr2_+_26915584 0.08 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr11_-_85430356 0.08 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr20_-_3140490 0.07 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr18_+_20494078 0.07 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr8_+_110656344 0.07 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 1.0 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.3 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.3 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 2.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:1903181 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0035696 egg activation(GO:0007343) monocyte extravasation(GO:0035696) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:2000523 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005715 late recombination nodule(GO:0005715)
0.1 16.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.0 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3 3.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.1 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 19.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade