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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EVX2

Z-value: 0.19

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Transcription factors associated with EVX2

Gene Symbol Gene ID Gene Info
EVX2
ENSG00000174279.4 even-skipped homeobox 2

Activity profile of EVX2 motif

Sorted Z-values of EVX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_41057818 0.10 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr12_+_64798826 0.07 ENST00000540203.1
XPOT
exportin, tRNA
chr20_-_50418947 0.07 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr4_+_144354644 0.06 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr16_+_53133070 0.05 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr13_+_78315528 0.04 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr4_-_41884620 0.04 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr15_-_55562451 0.04 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr2_-_8715616 0.04 ENST00000418358.1
AC011747.3
AC011747.3
chr3_-_48659193 0.04 ENST00000330862.3
TMEM89
transmembrane protein 89
chr15_-_55562479 0.03 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr17_-_40337470 0.03 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_-_9929581 0.03 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr6_-_62996066 0.03 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr1_-_151431674 0.03 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr20_+_43990576 0.02 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr12_+_15699286 0.02 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr5_-_96478466 0.02 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr1_-_151431647 0.01 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr12_+_28410128 0.01 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr20_+_30467600 0.01 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr15_-_55563072 0.01 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr17_+_18086392 0.01 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr1_-_151431909 0.00 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr15_-_55562582 0.00 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr1_+_28261533 0.00 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_160160346 0.00 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)