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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXC1

Z-value: 1.31

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Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
FOXC1
ENSG00000054598.5 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg19_v2_chr6_+_1610681_1610681-0.691.3e-01Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_66918558 1.35 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr8_+_97597148 1.13 ENST00000521590.1
SDC2
syndecan 2
chr12_-_106480587 1.06 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr6_-_152489484 0.79 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr15_+_76352178 0.72 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr16_+_2570340 0.72 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr7_+_120590803 0.68 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr1_+_239882842 0.67 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr1_-_228135599 0.63 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr5_-_39424961 0.62 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_208030295 0.60 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_-_48546324 0.58 ENST00000508540.1
CHAD
chondroadherin
chr14_+_37126765 0.58 ENST00000402703.2
PAX9
paired box 9
chr10_+_114710425 0.54 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr12_+_43086018 0.53 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr16_-_21875424 0.51 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr12_-_49453557 0.49 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr17_+_79953310 0.47 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr2_-_72374948 0.47 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr11_-_126870655 0.46 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr10_+_105314881 0.46 ENST00000437579.1
NEURL
neuralized E3 ubiquitin protein ligase 1
chr3_-_49131614 0.46 ENST00000450685.1
QRICH1
glutamine-rich 1
chr19_-_13900972 0.45 ENST00000397557.1
AC008686.1
Uncharacterized protein
chr6_-_152639479 0.45 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_+_114710211 0.44 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr19_+_17516909 0.44 ENST00000601007.1
ENST00000594913.1
ENST00000599975.1
ENST00000600514.1
CTD-2521M24.9
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
chr19_-_47734448 0.43 ENST00000439096.2
BBC3
BCL2 binding component 3
chr1_+_12524965 0.43 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr7_+_139528952 0.43 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr17_+_7533439 0.43 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr10_+_114709999 0.42 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_-_61190754 0.42 ENST00000216513.4
SIX4
SIX homeobox 4
chr2_+_166095898 0.41 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr16_-_88772670 0.41 ENST00000562544.1
RNF166
ring finger protein 166
chr4_+_124571409 0.41 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr6_-_10747802 0.40 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr7_-_14029283 0.40 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr12_+_122516626 0.40 ENST00000319080.7
MLXIP
MLX interacting protein
chr2_-_161056802 0.40 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr6_-_32122106 0.40 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr9_+_103340354 0.38 ENST00000307584.5
MURC
muscle-related coiled-coil protein
chr2_-_161056762 0.38 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr9_+_134103496 0.37 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr1_+_39670423 0.37 ENST00000536367.1
MACF1
microtubule-actin crosslinking factor 1
chr17_+_72426891 0.36 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_+_42120283 0.35 ENST00000542534.2
ENST00000397299.4
ENST00000408047.1
ENST00000431823.1
ENST00000382448.4
ENST00000342159.4
PLA2G4B
JMJD7
JMJD7-PLA2G4B
phospholipase A2, group IVB (cytosolic)
jumonji domain containing 7
JMJD7-PLA2G4B readthrough
chr3_-_193096600 0.35 ENST00000446087.1
ENST00000342358.4
ATP13A5
ATPase type 13A5
chr16_+_8715536 0.35 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
METTL22
methyltransferase like 22
chr10_+_71561649 0.34 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr1_-_94079648 0.34 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr7_+_139529040 0.34 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr6_+_18387570 0.33 ENST00000259939.3
RNF144B
ring finger protein 144B
chr14_-_61191049 0.33 ENST00000556952.3
SIX4
SIX homeobox 4
chr19_+_17516531 0.33 ENST00000528911.1
ENST00000528604.1
ENST00000595892.1
ENST00000500836.2
ENST00000598546.1
ENST00000600369.1
ENST00000598356.1
ENST00000594426.1
MVB12A
CTD-2521M24.9
multivesicular body subunit 12A
CTD-2521M24.9
chr12_+_10365082 0.33 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr5_+_112312416 0.33 ENST00000389063.2
DCP2
decapping mRNA 2
chr19_+_3880581 0.32 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr19_+_36024310 0.32 ENST00000222286.4
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_-_153931052 0.32 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr3_+_187957646 0.31 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_72375167 0.31 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr4_-_153303658 0.31 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_72509751 0.31 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr17_-_48546232 0.30 ENST00000258969.4
CHAD
chondroadherin
chr3_-_114343039 0.29 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_86848933 0.29 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr10_-_118032697 0.29 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr12_+_131438443 0.29 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr6_+_10747986 0.28 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr8_-_123793048 0.28 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr11_+_113930955 0.28 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr19_+_782755 0.28 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr7_-_72972319 0.27 ENST00000223368.2
BCL7B
B-cell CLL/lymphoma 7B
chr8_-_134309335 0.27 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr3_-_71632894 0.26 ENST00000493089.1
FOXP1
forkhead box P1
chr2_+_58655461 0.26 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr22_-_43036607 0.26 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr10_-_118031778 0.26 ENST00000369236.1
GFRA1
GDNF family receptor alpha 1
chr3_+_119316689 0.26 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr12_+_10365404 0.25 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr19_-_36523529 0.25 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr19_-_52255107 0.25 ENST00000595042.1
ENST00000304748.4
FPR1
formyl peptide receptor 1
chr8_-_134309823 0.24 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr3_-_187454281 0.24 ENST00000232014.4
BCL6
B-cell CLL/lymphoma 6
chr10_+_114710516 0.24 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_-_102268628 0.24 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_23340822 0.23 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr7_-_27219849 0.23 ENST00000396344.4
HOXA10
homeobox A10
chr19_+_29493486 0.23 ENST00000589821.1
CTD-2081K17.2
CTD-2081K17.2
chr11_-_46615498 0.23 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
AMBRA1
autophagy/beclin-1 regulator 1
chr4_-_164534657 0.23 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_-_131132658 0.22 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr21_+_17791648 0.22 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_+_10748019 0.22 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr21_+_17791838 0.22 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_71017791 0.22 ENST00000502294.1
C4orf40
chromosome 4 open reading frame 40
chr12_+_59989918 0.22 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_+_129906660 0.22 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr4_-_99578789 0.22 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr16_+_8715574 0.22 ENST00000561758.1
METTL22
methyltransferase like 22
chr7_+_79998864 0.22 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_128175997 0.21 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr19_-_36523709 0.21 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr12_-_49333446 0.21 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr17_+_8924837 0.21 ENST00000173229.2
NTN1
netrin 1
chr17_+_57408994 0.20 ENST00000312655.4
YPEL2
yippee-like 2 (Drosophila)
chr4_+_71587669 0.20 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr2_+_85981008 0.20 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr6_-_52926539 0.20 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr11_+_130184888 0.20 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1
RP11-121M22.1
chr17_+_41363854 0.20 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr15_+_67418047 0.19 ENST00000540846.2
SMAD3
SMAD family member 3
chr15_-_50411412 0.19 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr3_-_57233966 0.19 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr22_-_39268308 0.19 ENST00000407418.3
CBX6
chromobox homolog 6
chr15_-_72563585 0.19 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_+_18957500 0.19 ENST00000375375.3
PAX7
paired box 7
chr18_+_21032781 0.19 ENST00000339486.3
RIOK3
RIO kinase 3
chr6_-_5260963 0.18 ENST00000464010.1
ENST00000468929.1
ENST00000480566.1
LYRM4
LYR motif containing 4
chr11_-_66112555 0.18 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr3_-_57326704 0.18 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr5_+_159614374 0.18 ENST00000393980.4
FABP6
fatty acid binding protein 6, ileal
chr3_-_127455200 0.17 ENST00000398101.3
MGLL
monoglyceride lipase
chrX_+_22050546 0.17 ENST00000379374.4
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr12_-_122017542 0.17 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr14_-_92572894 0.17 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr17_-_27503770 0.17 ENST00000533112.1
MYO18A
myosin XVIIIA
chr6_+_45296048 0.17 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr11_+_57791353 0.17 ENST00000335397.3
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr9_+_127054217 0.17 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr11_+_46639071 0.16 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13
autophagy related 13
chr1_+_43855560 0.16 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr1_+_174846570 0.16 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_22778337 0.16 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr10_+_71561630 0.16 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr16_+_22517166 0.16 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr19_-_40919271 0.16 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr3_+_178866199 0.16 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr14_+_69726656 0.15 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_+_18958008 0.15 ENST00000420770.2
ENST00000400661.3
PAX7
paired box 7
chr3_-_49131788 0.15 ENST00000395443.2
ENST00000411682.1
QRICH1
glutamine-rich 1
chr3_-_157221128 0.15 ENST00000392833.2
ENST00000362010.2
VEPH1
ventricular zone expressed PH domain-containing 1
chr11_-_8739383 0.15 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr11_-_6440624 0.15 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr20_-_17511962 0.15 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr13_+_36050881 0.15 ENST00000537702.1
NBEA
neurobeachin
chr3_-_168865522 0.15 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr2_-_220042825 0.15 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chrX_+_135730297 0.15 ENST00000370629.2
CD40LG
CD40 ligand
chr16_+_56969284 0.15 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_+_69726864 0.15 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr11_-_6440283 0.15 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr10_-_4285923 0.15 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr6_+_108882069 0.14 ENST00000406360.1
FOXO3
forkhead box O3
chr5_+_60933634 0.14 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr10_+_71562180 0.14 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr4_-_83483094 0.14 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr11_+_46638805 0.14 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
ATG13
autophagy related 13
chr19_+_42806250 0.14 ENST00000598490.1
ENST00000341747.3
PRR19
proline rich 19
chr4_-_105416039 0.13 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_+_147096837 0.13 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_129732467 0.13 ENST00000413543.2
PHF17
jade family PHD finger 1
chrX_-_19688475 0.13 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_68797580 0.13 ENST00000539404.1
RP11-81H14.2
RP11-81H14.2
chr11_+_93479588 0.13 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr15_+_58430567 0.13 ENST00000536493.1
AQP9
aquaporin 9
chr20_+_9049303 0.13 ENST00000407043.2
ENST00000441846.1
PLCB4
phospholipase C, beta 4
chr14_-_74226961 0.13 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chrX_+_135730373 0.13 ENST00000370628.2
CD40LG
CD40 ligand
chr3_-_11623804 0.12 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr1_-_43855444 0.12 ENST00000372455.4
MED8
mediator complex subunit 8
chr11_+_8040739 0.12 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr6_-_42418999 0.12 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr3_-_114477787 0.12 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_214013353 0.12 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_19811132 0.12 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr1_-_94312706 0.12 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr2_+_28974668 0.12 ENST00000296122.6
ENST00000395366.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_-_114477962 0.12 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr16_-_4817129 0.12 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr6_-_154567984 0.12 ENST00000517438.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr17_+_40925454 0.12 ENST00000253794.2
ENST00000590339.1
ENST00000589520.1
VPS25
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr5_+_40841276 0.12 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr14_-_24020858 0.11 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chr1_-_151431909 0.11 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chrX_-_117107542 0.11 ENST00000371878.1
KLHL13
kelch-like family member 13
chr9_-_139258235 0.11 ENST00000371738.3
DNLZ
DNL-type zinc finger
chr5_+_98104978 0.11 ENST00000308234.7
RGMB
repulsive guidance molecule family member b
chr6_+_15401075 0.11 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr16_+_30064444 0.11 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30064411 0.11 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr4_+_15376165 0.11 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr14_-_20774092 0.11 ENST00000423949.2
ENST00000553828.1
ENST00000258821.3
TTC5
tetratricopeptide repeat domain 5
chr17_+_28268623 0.11 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr17_-_19290483 0.11 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr7_-_99698338 0.11 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr3_+_48481658 0.11 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr3_+_46449049 0.10 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr7_+_28452130 0.10 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr5_-_115872124 0.10 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.9 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.6 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 1.1 GO:0008218 bioluminescence(GO:0008218)
0.2 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.8 GO:0019075 virus maturation(GO:0019075)
0.1 0.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.3 GO:0050760 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 1.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.5 GO:0001555 oocyte growth(GO:0001555)
0.1 0.3 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 1.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.5 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:1902510 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.5 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.0 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0072189 ureter development(GO:0072189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 0.7 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254)
0.0 0.4 GO:0005497 androgen binding(GO:0005497)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0046790 virion binding(GO:0046790)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL