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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.77

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Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
FOXD1
ENSG00000251493.2 forkhead box D1
FOXO1
ENSG00000150907.6 forkhead box O1
FOXO6
ENSG00000204060.4 forkhead box O6
FOXG1
ENSG00000176165.7 forkhead box G1
FOXP1
ENSG00000114861.14 forkhead box P1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD1hg19_v2_chr5_-_72744336_727443590.758.8e-02Click!
FOXP1hg19_v2_chr3_-_71632894_716329090.749.2e-02Click!
FOXO1hg19_v2_chr13_-_41240717_41240735-0.612.0e-01Click!
FOXG1hg19_v2_chr14_+_29236269_292362870.582.3e-01Click!
FOXO6hg19_v2_chr1_+_41827594_418275940.286.0e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_134832808 1.24 ENST00000275767.3
TMEM140
transmembrane protein 140
chr2_+_66918558 1.23 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr1_-_12679171 1.15 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr10_-_101841588 1.06 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr6_-_32122106 1.04 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr5_-_38557561 0.96 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr16_+_4666475 0.92 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr4_+_124571409 0.81 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr8_-_8318847 0.79 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr22_-_31688431 0.78 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr4_+_183370146 0.75 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr13_-_46716969 0.70 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_99698338 0.69 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr7_+_134551583 0.69 ENST00000435928.1
CALD1
caldesmon 1
chr2_+_97481974 0.62 ENST00000377060.3
ENST00000305510.3
CNNM3
cyclin M3
chr19_-_47734448 0.62 ENST00000439096.2
BBC3
BCL2 binding component 3
chr17_+_72426891 0.60 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_-_30107491 0.58 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3
yippee-like 3 (Drosophila)
chr4_-_141075330 0.56 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chr14_-_69262789 0.56 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr19_-_50380536 0.55 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr3_-_46608010 0.55 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr5_-_16742330 0.55 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr19_-_45909585 0.54 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr14_+_23067146 0.53 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr12_+_6881678 0.53 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr5_+_121465234 0.52 ENST00000504912.1
ENST00000505843.1
ZNF474
zinc finger protein 474
chr19_+_50380917 0.51 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr18_-_2982869 0.51 ENST00000584915.1
LPIN2
lipin 2
chr9_-_128246769 0.50 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr6_+_84563295 0.50 ENST00000369687.1
RIPPLY2
ripply transcriptional repressor 2
chr10_-_99094458 0.49 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr7_-_84122033 0.49 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_86650077 0.49 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_27880174 0.46 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr9_-_135819987 0.45 ENST00000298552.3
ENST00000403810.1
TSC1
tuberous sclerosis 1
chr22_-_45404819 0.45 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHF21B
PHD finger protein 21B
chr11_+_117049445 0.45 ENST00000324225.4
ENST00000532960.1
SIDT2
SID1 transmembrane family, member 2
chr16_-_57831914 0.45 ENST00000421376.2
KIFC3
kinesin family member C3
chr16_-_57831676 0.45 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
KIFC3
kinesin family member C3
chrX_-_48937531 0.45 ENST00000473974.1
ENST00000475880.1
ENST00000396681.4
ENST00000553851.1
ENST00000471338.1
ENST00000476728.1
ENST00000376368.2
ENST00000485908.1
ENST00000376372.3
ENST00000376358.3
WDR45
AF196779.12
WD repeat domain 45
WD repeat domain phosphoinositide-interacting protein 4
chr3_-_185826718 0.44 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr8_+_77593448 0.44 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr5_-_142065612 0.44 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr1_+_227127981 0.44 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3
aarF domain containing kinase 3
chr6_-_33168391 0.43 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr9_+_27109133 0.43 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr18_+_3449330 0.43 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr17_+_72427477 0.43 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_12677714 0.43 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr14_+_23067166 0.42 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr14_+_56584414 0.42 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr5_+_176853702 0.42 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr20_+_44035200 0.42 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_+_13906250 0.41 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr10_+_43932282 0.41 ENST00000431662.1
ENST00000315429.6
ZNF487
zinc finger protein 487
chr22_-_31688381 0.41 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr10_+_99400443 0.41 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr7_+_30174574 0.41 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr17_+_41561317 0.41 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr9_+_140125385 0.41 ENST00000361134.2
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr19_+_41725140 0.40 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr7_+_114055052 0.39 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr8_+_77593474 0.39 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr1_+_65730385 0.39 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr14_-_54418598 0.39 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr8_+_99956759 0.38 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr1_+_33722080 0.38 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr1_-_207095324 0.38 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr17_+_26662597 0.38 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr7_-_105332084 0.38 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr1_-_161337662 0.38 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr5_+_176853669 0.38 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr19_+_50380682 0.38 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr19_-_6057282 0.38 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr16_-_84150492 0.38 ENST00000343411.3
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr16_-_57832004 0.37 ENST00000562503.1
KIFC3
kinesin family member C3
chr15_+_80733570 0.36 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr11_+_33061543 0.36 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr3_-_48956818 0.36 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr2_-_27434611 0.36 ENST00000408041.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr3_+_9691117 0.36 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr8_+_99956662 0.36 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr1_-_168106536 0.36 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161
G protein-coupled receptor 161
chr7_-_5463175 0.35 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr1_-_153931052 0.35 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr17_+_59477233 0.35 ENST00000240328.3
TBX2
T-box 2
chr17_+_73455788 0.34 ENST00000581519.1
KIAA0195
KIAA0195
chr20_+_56964169 0.34 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr17_-_42580738 0.34 ENST00000585614.1
ENST00000591680.1
ENST00000434000.1
ENST00000588554.1
ENST00000592154.1
GPATCH8
G patch domain containing 8
chr6_-_42016385 0.33 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr11_+_844406 0.33 ENST00000397404.1
TSPAN4
tetraspanin 4
chr1_-_94079648 0.33 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chrX_-_48937503 0.33 ENST00000322995.8
WDR45
WD repeat domain 45
chr2_-_26205550 0.33 ENST00000405914.1
KIF3C
kinesin family member 3C
chr11_-_72504637 0.33 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_-_42812143 0.33 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr6_-_88875628 0.33 ENST00000551417.1
CNR1
cannabinoid receptor 1 (brain)
chr6_-_42418999 0.33 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr8_+_24151620 0.32 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr3_-_71632894 0.32 ENST00000493089.1
FOXP1
forkhead box P1
chr9_+_27109440 0.32 ENST00000519080.1
TEK
TEK tyrosine kinase, endothelial
chr10_+_104535994 0.32 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr19_-_42916499 0.32 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr2_+_111878483 0.32 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr14_+_24584056 0.32 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_152623231 0.31 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_84630367 0.31 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_96588368 0.31 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr5_+_121465207 0.31 ENST00000296600.4
ZNF474
zinc finger protein 474
chr12_-_116714564 0.31 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr3_+_48956249 0.31 ENST00000452882.1
ENST00000430423.1
ENST00000356401.4
ENST00000449376.1
ENST00000420814.1
ENST00000449729.1
ENST00000433170.1
ARIH2
ariadne RBR E3 ubiquitin protein ligase 2
chr3_-_141868293 0.30 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_-_69262916 0.30 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr11_-_72504681 0.30 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
STARD10
StAR-related lipid transfer (START) domain containing 10
chr16_-_87729753 0.30 ENST00000538868.1
AC010536.1
Uncharacterized protein; cDNA FLJ45526 fis, clone BRTHA2027227
chr17_+_58755184 0.30 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr10_+_123923105 0.29 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr20_+_306221 0.29 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr20_+_306177 0.29 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr1_-_179112173 0.29 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr16_+_1832902 0.29 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr15_-_83240783 0.29 ENST00000568994.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr16_+_4896659 0.29 ENST00000592120.1
UBN1
ubinuclein 1
chrX_+_135251835 0.29 ENST00000456445.1
FHL1
four and a half LIM domains 1
chrX_-_19688475 0.28 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr20_+_2082494 0.28 ENST00000246032.3
STK35
serine/threonine kinase 35
chr14_+_32798547 0.28 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr7_+_28448995 0.28 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr3_+_193853927 0.28 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr1_+_198126209 0.28 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr2_-_198175495 0.28 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44
ankyrin repeat domain 44
chr17_+_26662730 0.27 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr8_-_133772870 0.27 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr17_-_1463095 0.27 ENST00000575895.1
ENST00000573056.1
PITPNA
phosphatidylinositol transfer protein, alpha
chr2_+_27665232 0.27 ENST00000543753.1
ENST00000288873.3
KRTCAP3
keratinocyte associated protein 3
chr20_-_44519839 0.27 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr12_-_88423164 0.27 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr1_-_8585945 0.27 ENST00000377464.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr5_-_150460914 0.27 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr5_+_133859996 0.27 ENST00000512386.1
PHF15
jade family PHD finger 2
chr4_-_152149033 0.26 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr5_-_150460539 0.26 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_45956822 0.26 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chrX_-_48937684 0.26 ENST00000465382.1
ENST00000423215.2
WDR45
WD repeat domain 45
chr2_+_20650796 0.26 ENST00000448241.1
AC023137.2
AC023137.2
chr17_+_26662679 0.26 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_+_27665289 0.26 ENST00000407293.1
KRTCAP3
keratinocyte associated protein 3
chr1_+_87797351 0.26 ENST00000370542.1
LMO4
LIM domain only 4
chr3_+_181429704 0.26 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr15_-_34610962 0.26 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_26205340 0.25 ENST00000264712.3
KIF3C
kinesin family member 3C
chr10_-_105421427 0.25 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr9_+_27109392 0.25 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr10_-_90751038 0.24 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_3663502 0.24 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr6_-_131211534 0.24 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr20_+_48909240 0.24 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr2_-_190044480 0.24 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_+_229440129 0.24 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr4_-_40632605 0.24 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr3_+_52245458 0.24 ENST00000459884.1
ALAS1
aminolevulinate, delta-, synthase 1
chr7_+_28725585 0.24 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr1_-_179112189 0.23 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr3_+_187957646 0.23 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chrX_-_106146547 0.23 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr16_-_4896205 0.23 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr8_-_124553437 0.23 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr12_-_56367101 0.23 ENST00000549233.2
PMEL
premelanosome protein
chr7_-_84121858 0.23 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_+_108977520 0.23 ENST00000540898.1
FOXO3
forkhead box O3
chr1_+_12524965 0.23 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr9_+_140125209 0.23 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr2_-_27434635 0.23 ENST00000401463.1
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_-_39826639 0.22 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr16_+_57680840 0.22 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56
G protein-coupled receptor 56
chr22_-_37505449 0.22 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr5_-_13944652 0.22 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr12_+_121416340 0.22 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr5_-_36301984 0.22 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr18_+_9475668 0.22 ENST00000383432.3
RALBP1
ralA binding protein 1
chr7_-_83278322 0.22 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_-_57089774 0.22 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr9_+_2159850 0.21 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_-_67597789 0.21 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr1_+_200011711 0.21 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr1_+_40862501 0.21 ENST00000539317.1
SMAP2
small ArfGAP2
chrX_-_54070607 0.21 ENST00000338154.6
ENST00000338946.6
PHF8
PHD finger protein 8
chr19_+_12902289 0.21 ENST00000302754.4
JUNB
jun B proto-oncogene
chr9_+_109694914 0.21 ENST00000542028.1
ZNF462
zinc finger protein 462
chr10_+_75668916 0.21 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr11_+_63606373 0.21 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr17_+_36886478 0.21 ENST00000439660.2
CISD3
CDGSH iron sulfur domain 3
chrX_-_106960285 0.21 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr1_+_3541543 0.20 ENST00000378344.2
ENST00000344579.5
TPRG1L
tumor protein p63 regulated 1-like
chr16_+_4421841 0.20 ENST00000304735.3
VASN
vasorin
chr12_-_111926342 0.20 ENST00000389154.3
ATXN2
ataxin 2
chr1_-_179851611 0.20 ENST00000610272.1
RP11-533E19.7
RP11-533E19.7
chr3_+_187930429 0.20 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_233877912 0.20 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030070 insulin processing(GO:0030070)
0.2 1.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.6 GO:0035623 renal glucose absorption(GO:0035623)
0.2 0.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.9 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 1.0 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 1.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.6 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 1.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.8 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.3 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.5 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.3 GO:0045632 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.5 GO:0051029 rRNA transport(GO:0051029)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.5 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 1.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.2 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 1.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:1902868 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.0 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0043132 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) NAD transport(GO:0043132)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.5 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 1.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.0 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.5 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0032648 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.0 0.6 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 1.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) negative regulation of cyclic nucleotide catabolic process(GO:0030806) regulation of cAMP catabolic process(GO:0030820) negative regulation of cAMP catabolic process(GO:0030821) regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.0 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.7 GO:0030425 dendrite(GO:0030425)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0038201 TOR complex(GO:0038201)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.4 GO:0033643 host cell part(GO:0033643)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.0 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.5 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 1.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 1.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.3 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0050693 DBD domain binding(GO:0050692) LBD domain binding(GO:0050693)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis