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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 0.87

Motif logo

Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.4 forkhead box D3
ENSG00000168269.7 forkhead box I1
ENSG00000103241.5 forkhead box F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD3hg19_v2_chr1_+_63788730_63788730-0.572.4e-01Click!
FOXF1hg19_v2_chr16_+_86544113_86544145-0.098.6e-01Click!

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_32083106 1.05 ENST00000442721.1
tenascin XB
chr15_+_63188009 0.99 ENST00000557900.1
RP11-1069G10.2
chr1_+_207277590 0.84 ENST00000367070.3
complement component 4 binding protein, alpha
chr1_-_27998689 0.74 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
interferon, alpha-inducible protein 6
chr4_-_99578776 0.73 ENST00000515287.1
tetraspanin 5
chr1_+_2258581 0.72 ENST00000600779.1
Uncharacterized protein
chr5_+_40841410 0.71 ENST00000381677.3
caspase recruitment domain family, member 6
chr1_+_95616933 0.67 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr4_+_89299994 0.64 ENST00000264346.7
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr5_+_125706998 0.61 ENST00000506445.1
GRAM domain containing 3
chr1_+_207277632 0.57 ENST00000421786.1
complement component 4 binding protein, alpha
chr4_+_89299885 0.55 ENST00000380265.5
ENST00000273960.3
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_136649311 0.55 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr12_+_25348186 0.54 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYR motif containing 5
chr17_-_46692457 0.53 ENST00000468443.1
homeobox B8
chr14_+_51026926 0.53 ENST00000557735.1
atlastin GTPase 1
chr11_+_17316870 0.53 ENST00000458064.2
nucleobindin 2
chr8_+_97597148 0.52 ENST00000521590.1
syndecan 2
chr13_+_50070077 0.48 ENST00000378319.3
ENST00000426879.1
PHD finger protein 11
chr18_-_52626622 0.48 ENST00000591504.1
coiled-coil domain containing 68
chr17_-_39150385 0.47 ENST00000391586.1
keratin associated protein 3-3
chr3_-_148939598 0.46 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr12_+_27849378 0.41 ENST00000310791.2
RAB15 effector protein
chr14_+_51026844 0.41 ENST00000554886.1
atlastin GTPase 1
chr18_+_29769978 0.40 ENST00000269202.6
ENST00000581447.1
meprin A, beta
chr4_-_103266626 0.39 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr13_-_86373536 0.38 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr8_+_86999516 0.37 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr11_+_34654011 0.37 ENST00000531794.1
ets homologous factor
chr19_-_46627914 0.36 ENST00000341415.2
IGF-like family member 3
chr6_+_53794780 0.36 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
muscular LMNA-interacting protein
RP11-411K7.1
chr7_+_106415457 0.36 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
chr14_-_62217779 0.36 ENST00000554254.1
HIF1A antisense RNA 2
chr14_+_58797974 0.36 ENST00000417477.2
AT rich interactive domain 4A (RBP1-like)
chr2_-_111291587 0.36 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr8_+_52730143 0.35 ENST00000415643.1
Uncharacterized protein
chr2_-_152146385 0.35 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr12_-_71551652 0.34 ENST00000546561.1
tetraspanin 8
chr4_-_105416039 0.34 ENST00000394767.2
CXXC finger protein 4
chr12_-_121476959 0.34 ENST00000339275.5
2'-5'-oligoadenylate synthetase-like
chr22_+_37678505 0.34 ENST00000402997.1
ENST00000405206.3
cytohesin 4
chrX_-_20237059 0.34 ENST00000457145.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_95174445 0.33 ENST00000509418.1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chrM_+_10464 0.32 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr10_-_4720333 0.32 ENST00000430998.2
long intergenic non-protein coding RNA 704
chr7_+_95115210 0.31 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr7_-_75401513 0.30 ENST00000005180.4
chemokine (C-C motif) ligand 26
chr12_+_25348139 0.30 ENST00000557540.2
ENST00000381356.4
LYR motif containing 5
chr2_+_28974489 0.29 ENST00000455580.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr9_-_86432547 0.29 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr5_-_111091948 0.29 ENST00000447165.2
neuronal regeneration related protein
chr3_-_145940214 0.28 ENST00000481701.1
phospholipid scramblase 4
chr5_-_43412418 0.28 ENST00000537013.1
ENST00000361115.4
chemokine (C-C motif) ligand 28
chr15_+_38964048 0.28 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
chrM_+_8366 0.27 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr4_-_74486109 0.27 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr10_+_80008505 0.27 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
long intergenic non-protein coding RNA 856
chr14_+_21492331 0.27 ENST00000533984.1
ENST00000532213.2
AL161668.5
chr4_+_71587669 0.26 ENST00000381006.3
ENST00000226328.4
RUN and FYVE domain containing 3
chr4_-_99578789 0.25 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chrM_+_4431 0.25 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr8_-_128231299 0.25 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr12_-_99038732 0.25 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBKB interacting protein
chr4_-_140544386 0.24 ENST00000561977.1
RP11-308D13.3
chr1_-_28384598 0.24 ENST00000373864.1
eyes absent homolog 3 (Drosophila)
chr5_+_68665608 0.24 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17 homolog (S. pombe)
chr8_-_95449155 0.24 ENST00000481490.2
fibrinogen silencer binding protein
chr2_+_198380289 0.24 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr18_+_68002675 0.23 ENST00000584919.1
Uncharacterized protein
chr8_-_108510224 0.23 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr12_+_28605426 0.23 ENST00000542801.1
coiled-coil domain containing 91
chr1_-_150669500 0.22 ENST00000271732.3
golgi phosphoprotein 3-like
chr5_-_41510725 0.22 ENST00000328457.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr4_+_76871883 0.22 ENST00000599764.1
Uncharacterized protein
chr8_-_90993869 0.22 ENST00000517772.1
nibrin
chr6_+_21666633 0.22 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr1_+_184020811 0.22 ENST00000361641.1
TSEN15 tRNA splicing endonuclease subunit
chr12_+_59989918 0.22 ENST00000547379.1
ENST00000549465.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_232575168 0.22 ENST00000440384.1
prothymosin, alpha
chr9_+_116343192 0.22 ENST00000471324.2
regulator of G-protein signaling 3
chr4_+_124317940 0.22 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_181845843 0.22 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr11_+_34642656 0.22 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr7_-_117512264 0.21 ENST00000454375.1
cortactin binding protein 2
chr3_-_57530051 0.21 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
dynein, axonemal, heavy chain 12
chr16_-_12062333 0.21 ENST00000597717.1
Uncharacterized protein
chr12_+_20963647 0.21 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr7_-_81635106 0.21 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_+_186330712 0.21 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr3_-_128902729 0.21 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CCHC-type zinc finger, nucleic acid binding protein
chr12_-_68696652 0.21 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr19_-_36297348 0.21 ENST00000589835.1
proline dehydrogenase (oxidase) 2
chr1_-_170043709 0.21 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr3_-_69402828 0.21 ENST00000460709.1
FERM domain containing 4B
chr8_-_117886563 0.21 ENST00000519837.1
ENST00000522699.1
RAD21 homolog (S. pombe)
chr7_-_14029283 0.21 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr8_+_67104940 0.20 ENST00000517689.1
long intergenic non-protein coding RNA 967
chr7_-_32534850 0.20 ENST00000409952.3
ENST00000409909.3
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_104159999 0.20 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chrX_-_74743080 0.20 ENST00000373367.3
zinc finger, DHHC-type containing 15
chr4_+_130014836 0.20 ENST00000502887.1
chromosome 4 open reading frame 33
chr4_-_99850243 0.20 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr4_+_79567362 0.19 ENST00000512322.1
long intergenic non-protein coding RNA 1094
chr4_+_17578815 0.19 ENST00000226299.4
leucine aminopeptidase 3
chr14_+_56127960 0.19 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr8_+_104383759 0.19 ENST00000415886.2
collagen triple helix repeat containing 1
chr12_+_20963632 0.19 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr15_-_59041768 0.19 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr4_+_103790462 0.19 ENST00000503643.1
CDGSH iron sulfur domain 2
chr3_-_128902759 0.19 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
CCHC-type zinc finger, nucleic acid binding protein
chr19_-_52531600 0.18 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr9_+_26956474 0.18 ENST00000429045.2
intraflagellar transport 74 homolog (Chlamydomonas)
chr2_-_188419200 0.18 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_10324716 0.18 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr22_+_38035623 0.18 ENST00000336738.5
ENST00000442465.2
SH3-domain binding protein 1
chr2_+_38177575 0.18 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr2_-_188419078 0.18 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_191878162 0.18 ENST00000540176.1
signal transducer and activator of transcription 1, 91kDa
chr21_+_33671160 0.18 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr3_-_170459154 0.18 ENST00000473110.1
RP11-373E16.4
chr6_+_125524785 0.17 ENST00000392482.2
tumor protein D52-like 1
chr11_-_112034803 0.17 ENST00000528832.1
interleukin 18 (interferon-gamma-inducing factor)
chr12_+_72061563 0.17 ENST00000551238.1
THAP domain containing, apoptosis associated protein 2
chr1_-_179457805 0.17 ENST00000600581.1
Uncharacterized protein
chr4_-_155533787 0.17 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr15_+_71185148 0.17 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr9_-_3469181 0.17 ENST00000366116.2
Uncharacterized protein
chr9_+_26956371 0.17 ENST00000380062.5
ENST00000518614.1
intraflagellar transport 74 homolog (Chlamydomonas)
chr17_-_74547256 0.17 ENST00000589145.1
cytoglobin
chr3_-_193096600 0.17 ENST00000446087.1
ENST00000342358.4
ATPase type 13A5
chr11_-_63330842 0.17 ENST00000255695.1
HRAS-like suppressor 2
chr5_-_41510656 0.17 ENST00000377801.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_+_150382781 0.16 ENST00000223293.5
ENST00000474605.1
GTPase, IMAP family member 2
chr4_-_153303658 0.16 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_-_46142615 0.16 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr4_-_147442817 0.16 ENST00000507030.1
solute carrier family 10, member 7
chr15_-_96590126 0.16 ENST00000561051.1
RP11-4G2.1
chr4_-_147443043 0.16 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr17_-_40215075 0.16 ENST00000436535.3
zinc finger protein 385C
chr9_+_42671887 0.16 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr1_+_18957500 0.16 ENST00000375375.3
paired box 7
chr5_+_96271141 0.16 ENST00000231368.5
leucyl/cystinyl aminopeptidase
chrM_+_10758 0.16 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr14_+_56127989 0.16 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr3_-_195310802 0.16 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr15_-_34447023 0.16 ENST00000560310.1
katanin p80 subunit B-like 1
chr7_+_7811992 0.16 ENST00000406829.1
RPA3 antisense RNA 1
chr10_-_126849626 0.16 ENST00000530884.1
C-terminal binding protein 2
chr22_-_50970566 0.16 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr18_+_9103957 0.15 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr6_+_76330355 0.15 ENST00000483859.2
SUMO1/sentrin specific peptidase 6
chr8_-_117886732 0.15 ENST00000517485.1
RAD21 homolog (S. pombe)
chr16_-_53737722 0.15 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1-like
chr8_-_11660077 0.15 ENST00000533405.1
Uncharacterized protein
chrX_+_101975619 0.15 ENST00000457056.1
basic helix-loop-helix domain containing, class B, 9
chr5_-_176056974 0.15 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr14_+_20215587 0.15 ENST00000331723.1
olfactory receptor, family 4, subfamily Q, member 3
chr14_+_67831576 0.15 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr12_+_29302119 0.15 ENST00000536681.3
fatty acyl CoA reductase 2
chr22_-_50970506 0.15 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr17_-_29641104 0.15 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr5_+_179921344 0.15 ENST00000261951.4
CCR4-NOT transcription complex, subunit 6
chr7_-_92777606 0.15 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr4_+_155484155 0.15 ENST00000509493.1
fibrinogen beta chain
chr8_-_82754193 0.15 ENST00000519817.1
ENST00000521773.1
ENST00000523757.1
sorting nexin 16
chr2_-_211341411 0.15 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr7_+_107531580 0.15 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr6_-_154751629 0.14 ENST00000424998.1
CNKSR family member 3
chr13_-_40924439 0.14 ENST00000400432.3
RP11-172E9.2
chr2_-_165698662 0.14 ENST00000194871.6
ENST00000445474.2
cordon-bleu WH2 repeat protein-like 1
chr10_+_114709999 0.14 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_+_155484103 0.14 ENST00000302068.4
fibrinogen beta chain
chr8_-_82645082 0.14 ENST00000523361.1
zinc finger, AN1-type domain 1
chr11_-_112034780 0.14 ENST00000524595.1
interleukin 18 (interferon-gamma-inducing factor)
chr22_-_21360736 0.14 ENST00000547793.2
Uncharacterized protein
chr1_-_149459549 0.14 ENST00000369175.3
family with sequence similarity 72, member C
chr4_-_18023350 0.14 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr4_+_26585686 0.14 ENST00000505206.1
ENST00000511789.1
TBC1 domain family, member 19
chr3_-_139396560 0.14 ENST00000514703.1
ENST00000511444.1
nicotinamide nucleotide adenylyltransferase 3
chr18_+_9102669 0.14 ENST00000497577.2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr1_-_98510843 0.14 ENST00000413670.2
ENST00000538428.1
MIR137 host gene (non-protein coding)
chr22_-_50970919 0.14 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B
chrX_-_15683147 0.14 ENST00000380342.3
transmembrane protein 27
chr2_-_219925189 0.14 ENST00000295731.6
indian hedgehog
chr12_-_113658826 0.14 ENST00000546692.1
IQ motif containing D
chr6_+_47666275 0.14 ENST00000327753.3
ENST00000283303.2
G protein-coupled receptor 115
chr4_+_165675269 0.14 ENST00000507311.1
RP11-294O2.2
chr15_-_55657428 0.14 ENST00000568543.1
cell cycle progression 1
chr4_-_120225600 0.14 ENST00000399075.4
chromosome 4 open reading frame 3
chr14_-_58893832 0.14 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_-_43941023 0.14 ENST00000432420.1
ENST00000321596.5
ENST00000354127.4
ENST00000355438.2
ENST00000396879.1
ENST00000381761.1
cation channel, sperm associated 2
chr11_-_790060 0.14 ENST00000330106.4
cell cycle exit and neuronal differentiation 1
chr14_+_31028348 0.14 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2/M-phase specific E3 ubiquitin protein ligase
chrX_-_70331298 0.14 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
interleukin 2 receptor, gamma
chr2_+_70121075 0.14 ENST00000409116.1
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr11_+_114549108 0.13 ENST00000389586.4
ENST00000375475.5
neurexophilin and PC-esterase domain family, member 2
chr10_+_116524547 0.13 ENST00000436932.1
RP11-106M7.1
chr2_+_64068844 0.13 ENST00000337130.5
UDP-glucose pyrophosphorylase 2
chr1_-_63782888 0.13 ENST00000436475.2
long intergenic non-protein coding RNA 466
chr10_-_105110890 0.13 ENST00000369847.3
polycomb group ring finger 6

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 1.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.4 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0071264 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 0.2 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.1 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) leukocyte migration involved in immune response(GO:0002522)
0.0 0.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:1904346 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.0 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0090135 positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0061732 lipoate metabolic process(GO:0009106) mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.0 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.4 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.0 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:2000525 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0071899 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.7 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.0 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0046292 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.0 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.0 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.0 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.0 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.0 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.0 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.0 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.2 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0090079 translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.0 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.0 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL