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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GCM2

Z-value: 0.87

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Transcription factors associated with GCM2

Gene Symbol Gene ID Gene Info
GCM2
ENSG00000124827.6 glial cells missing transcription factor 2

Activity profile of GCM2 motif

Sorted Z-values of GCM2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_20307532 0.52 ENST00000405465.3
ENST00000248879.3
DGCR6L
DiGeorge syndrome critical region gene 6-like
chr20_+_1115821 0.49 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr19_-_19626351 0.46 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr16_+_28996572 0.44 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr1_+_156698743 0.43 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr16_+_2059872 0.43 ENST00000567649.1
NPW
neuropeptide W
chr12_-_50222187 0.43 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr19_-_38878632 0.42 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr2_-_220252068 0.42 ENST00000430206.1
ENST00000429013.1
DNPEP
aspartyl aminopeptidase
chr16_+_24857309 0.41 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr19_+_6361841 0.38 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr1_-_27226928 0.36 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr1_+_43824577 0.36 ENST00000310955.6
CDC20
cell division cycle 20
chr2_+_73114489 0.35 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr15_-_75248954 0.34 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr19_-_2236246 0.34 ENST00000587394.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr14_-_24912047 0.33 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr17_+_74075263 0.32 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr7_+_99933730 0.31 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr1_+_43824669 0.31 ENST00000372462.1
CDC20
cell division cycle 20
chr8_-_144897138 0.30 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr5_+_176514413 0.30 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr14_+_103394963 0.29 ENST00000559525.1
ENST00000559789.1
AMN
amnion associated transmembrane protein
chr3_-_138553779 0.29 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr16_+_2564254 0.29 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr5_+_159343688 0.29 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr14_-_24911448 0.29 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr19_-_51872233 0.28 ENST00000601435.1
ENST00000291715.1
CLDND2
claudin domain containing 2
chr19_+_10531150 0.27 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_+_31489344 0.27 ENST00000404574.1
SMTN
smoothelin
chr1_+_156698708 0.27 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr15_+_40861487 0.27 ENST00000315616.7
ENST00000559271.1
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr17_-_7218631 0.27 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr19_-_44084586 0.27 ENST00000599693.1
ENST00000598165.1
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_-_44365216 0.26 ENST00000358707.3
ENST00000457475.1
ENST00000440254.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr14_-_24911868 0.26 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr11_+_64001962 0.26 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr19_+_2236509 0.25 ENST00000221494.5
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr19_-_5720248 0.25 ENST00000360614.3
LONP1
lon peptidase 1, mitochondrial
chr8_-_144897549 0.25 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr19_+_36208877 0.25 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr5_-_176738883 0.24 ENST00000513169.1
ENST00000423571.2
ENST00000502529.1
ENST00000427908.2
MXD3
MAX dimerization protein 3
chr15_+_40733387 0.24 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr2_-_220252530 0.24 ENST00000521459.1
DNPEP
aspartyl aminopeptidase
chr15_-_45670924 0.24 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_-_31741757 0.24 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_156698234 0.24 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr12_+_56390964 0.24 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
SUOX
sulfite oxidase
chr19_-_49016847 0.24 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr19_+_41222998 0.24 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr6_-_41909191 0.24 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr17_-_46703826 0.23 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr16_-_2059748 0.23 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr2_-_193059634 0.23 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_+_104604916 0.23 ENST00000423312.2
KIF26A
kinesin family member 26A
chr20_-_30795511 0.23 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr14_-_24911971 0.23 ENST00000555365.1
ENST00000399395.3
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr11_+_64002292 0.23 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr19_-_10676666 0.22 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1
KRI1 homolog (S. cerevisiae)
chr6_-_32077100 0.22 ENST00000375244.3
ENST00000375247.2
TNXB
tenascin XB
chr14_+_23352374 0.22 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr22_-_43090992 0.22 ENST00000401850.1
A4GALT
alpha 1,4-galactosyltransferase
chr17_+_17206635 0.22 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr19_+_6361754 0.21 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr7_-_5463175 0.21 ENST00000399537.4
ENST00000430969.1
TNRC18
trinucleotide repeat containing 18
chr1_+_156105878 0.21 ENST00000508500.1
LMNA
lamin A/C
chr16_-_2059797 0.21 ENST00000563630.1
ZNF598
zinc finger protein 598
chr17_+_53342311 0.21 ENST00000226067.5
HLF
hepatic leukemia factor
chr1_+_20878932 0.21 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr15_+_101389945 0.21 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr15_+_40731920 0.21 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr2_-_220252603 0.21 ENST00000322176.7
ENST00000273075.4
DNPEP
aspartyl aminopeptidase
chr11_+_86511549 0.21 ENST00000533902.2
PRSS23
protease, serine, 23
chr14_+_77647966 0.21 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr17_-_76899275 0.21 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chrX_-_63005405 0.21 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr15_-_30261066 0.20 ENST00000558447.1
TJP1
tight junction protein 1
chr19_-_2236290 0.20 ENST00000591099.2
ENST00000586608.2
ENST00000326631.2
ENST00000587962.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr6_+_7107999 0.20 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr1_+_46640750 0.20 ENST00000372003.1
TSPAN1
tetraspanin 1
chr3_+_126707437 0.20 ENST00000393409.2
ENST00000251772.4
PLXNA1
plexin A1
chr14_-_59932044 0.20 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr18_+_3449695 0.19 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr19_+_6361795 0.19 ENST00000596149.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr7_+_150782945 0.19 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr7_+_2671568 0.19 ENST00000258796.7
TTYH3
tweety family member 3
chr2_-_220408430 0.19 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr11_+_66036004 0.19 ENST00000311481.6
ENST00000527397.1
RAB1B
RAB1B, member RAS oncogene family
chr11_-_73882057 0.19 ENST00000334126.7
ENST00000313663.7
C2CD3
C2 calcium-dependent domain containing 3
chr19_+_47105309 0.19 ENST00000599839.1
ENST00000596362.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr10_-_99531709 0.19 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr9_+_131873659 0.19 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr6_+_7108210 0.18 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr2_+_28615669 0.18 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr16_+_30759563 0.18 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr2_-_220435963 0.18 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr17_-_16472483 0.18 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287
zinc finger protein 287
chr6_-_31864977 0.18 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr20_-_44420507 0.18 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr1_-_223537401 0.18 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4
sushi domain containing 4
chr11_+_57435441 0.18 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr3_+_184032919 0.18 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr5_+_177027101 0.18 ENST00000029410.5
ENST00000510761.1
ENST00000505468.1
B4GALT7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
chr18_+_3449821 0.18 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr14_-_21566731 0.17 ENST00000360947.3
ZNF219
zinc finger protein 219
chr10_-_21786179 0.17 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr15_+_89164560 0.17 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr1_-_156698591 0.17 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr17_-_3796334 0.17 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr20_-_31172598 0.17 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr13_-_47471155 0.17 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr16_+_30759844 0.17 ENST00000565897.1
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr19_+_14142535 0.17 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr20_+_44420570 0.17 ENST00000372622.3
DNTTIP1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr1_+_44444865 0.16 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr6_+_7107830 0.16 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr15_-_41408409 0.16 ENST00000361937.3
INO80
INO80 complex subunit
chr8_+_37553261 0.16 ENST00000331569.4
ZNF703
zinc finger protein 703
chr1_-_67600639 0.16 ENST00000544837.1
ENST00000603691.1
C1orf141
chromosome 1 open reading frame 141
chr11_-_6341724 0.16 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr17_-_42908155 0.16 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr11_-_73882029 0.15 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr10_+_102790980 0.15 ENST00000393459.1
ENST00000224807.5
SFXN3
sideroflexin 3
chr1_+_214161272 0.15 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr14_+_24769043 0.15 ENST00000267425.3
ENST00000396802.3
NOP9
NOP9 nucleolar protein
chr19_-_41222775 0.15 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr2_-_220436248 0.15 ENST00000265318.4
OBSL1
obscurin-like 1
chr12_+_56618102 0.15 ENST00000267023.4
ENST00000380198.2
ENST00000341463.5
NABP2
nucleic acid binding protein 2
chr16_+_28996364 0.15 ENST00000564277.1
LAT
linker for activation of T cells
chr17_-_42907564 0.15 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr9_-_130635741 0.14 ENST00000223836.10
AK1
adenylate kinase 1
chrX_-_135962923 0.14 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr1_+_895930 0.14 ENST00000338591.3
KLHL17
kelch-like family member 17
chr11_+_73882144 0.14 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1
chr11_-_61197480 0.14 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr1_-_21503337 0.14 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_156698181 0.14 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr12_-_53343633 0.14 ENST00000546826.1
KRT8
keratin 8
chr7_-_44365020 0.13 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr20_-_23731569 0.13 ENST00000304749.2
CST1
cystatin SN
chr11_+_66406149 0.13 ENST00000578778.1
ENST00000483858.1
ENST00000398692.4
ENST00000510173.2
ENST00000506523.2
ENST00000530235.1
ENST00000532968.1
RBM4
RNA binding motif protein 4
chr17_+_7517264 0.13 ENST00000593717.1
ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
AC007421.1
SHBG
AC007421.1
sex hormone-binding globulin
chr18_+_55102917 0.13 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr22_+_21321531 0.13 ENST00000405089.1
ENST00000335375.5
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr15_+_89010923 0.13 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr2_+_179059365 0.13 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr11_-_73882249 0.13 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr15_+_89164520 0.13 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr5_+_176513868 0.12 ENST00000292408.4
FGFR4
fibroblast growth factor receptor 4
chr20_+_18269121 0.12 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
ZNF133
zinc finger protein 133
chr2_-_19558373 0.12 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr1_+_64239657 0.12 ENST00000371080.1
ENST00000371079.1
ROR1
receptor tyrosine kinase-like orphan receptor 1
chr19_+_6361440 0.12 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr16_+_30759700 0.12 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr3_-_12705600 0.12 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr7_+_2671663 0.12 ENST00000407643.1
TTYH3
tweety family member 3
chr11_+_66406088 0.12 ENST00000310092.7
ENST00000396053.4
ENST00000408993.2
RBM4
RNA binding motif protein 4
chr3_-_50605077 0.12 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr14_+_92980111 0.12 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr3_+_186383741 0.11 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr7_+_150811705 0.11 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chrX_+_120181457 0.11 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr14_-_21567009 0.11 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr17_+_79989500 0.11 ENST00000306897.4
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_17944806 0.11 ENST00000375408.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_+_179059188 0.11 ENST00000392505.2
ENST00000359685.3
ENST00000357080.4
ENST00000409045.3
OSBPL6
oxysterol binding protein-like 6
chr12_+_109915422 0.11 ENST00000280774.5
ENST00000536398.1
ENST00000539599.1
ENST00000342494.3
ENST00000340074.5
ENST00000540230.1
ENST00000537063.1
UBE3B
ubiquitin protein ligase E3B
chr6_+_37787704 0.11 ENST00000474522.1
ZFAND3
zinc finger, AN1-type domain 3
chr19_-_14316980 0.11 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr17_-_44270133 0.10 ENST00000262419.6
ENST00000393476.3
KANSL1
KAT8 regulatory NSL complex subunit 1
chr1_+_17944832 0.10 ENST00000167825.4
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_92085262 0.10 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr16_+_57438679 0.10 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr8_+_117950422 0.10 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chr15_+_43809797 0.10 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr19_+_19496624 0.10 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_159893507 0.10 ENST00000368096.1
TAGLN2
transgelin 2
chr11_+_7597639 0.09 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_-_71526813 0.09 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr11_+_63706444 0.09 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr19_-_10024496 0.09 ENST00000593091.1
OLFM2
olfactomedin 2
chr19_+_42829702 0.09 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8
chr5_+_137774706 0.09 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2
receptor accessory protein 2
chr16_+_71392616 0.09 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr12_+_56360605 0.09 ENST00000553376.1
ENST00000440311.2
ENST00000354056.4
CDK2
cyclin-dependent kinase 2
chr4_-_187112626 0.09 ENST00000596414.1
AC110771.1
Uncharacterized protein
chr20_-_60982330 0.09 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr1_-_55352834 0.09 ENST00000371269.3
DHCR24
24-dehydrocholesterol reductase
chr11_+_86511569 0.09 ENST00000441050.1
PRSS23
protease, serine, 23
chr19_+_5823813 0.09 ENST00000303212.2
NRTN
neurturin
chr7_-_36764004 0.09 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr19_-_10426663 0.09 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr21_+_27011584 0.09 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
JAM2
junctional adhesion molecule 2
chr17_-_44270270 0.09 ENST00000572904.1
KANSL1
KAT8 regulatory NSL complex subunit 1
chr17_+_7358889 0.09 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr1_+_150521876 0.09 ENST00000369041.5
ENST00000271643.4
ENST00000538795.1
ADAMTSL4
AL356356.1
ADAMTS-like 4
Protein LOC100996516
chr1_+_203595903 0.09 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr6_-_31704282 0.09 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr9_-_99417562 0.09 ENST00000375234.3
ENST00000446045.1
AAED1
AhpC/TSA antioxidant enzyme domain containing 1
chr11_-_61197187 0.08 ENST00000449811.1
ENST00000413232.1
ENST00000340437.4
ENST00000539952.1
ENST00000544585.1
ENST00000450000.1
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.3 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.3 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.4 GO:1903412 response to bile acid(GO:1903412)
0.1 0.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.5 GO:0021997 neural plate axis specification(GO:0021997)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 1.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:1903249 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) mesonephric duct morphogenesis(GO:0072180) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.9 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806) cyclin A1-CDK2 complex(GO:0097123) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.3 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.3 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling