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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GFI1

Z-value: 0.70

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Transcription factors associated with GFI1

Gene Symbol Gene ID Gene Info
GFI1
ENSG00000162676.7 growth factor independent 1 transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GFI1hg19_v2_chr1_-_92952433_929524890.216.9e-01Click!

Activity profile of GFI1 motif

Sorted Z-values of GFI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_47448102 0.72 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr12_-_106697974 0.43 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chrX_+_53078465 0.42 ENST00000375466.2
GPR173
G protein-coupled receptor 173
chr15_+_96875657 0.38 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_+_45908974 0.36 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr3_-_52002403 0.35 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr17_+_79495397 0.35 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr8_-_145642203 0.34 ENST00000526658.1
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chrX_+_103294483 0.31 ENST00000355016.3
H2BFM
H2B histone family, member M
chr3_-_33686925 0.30 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr17_+_3540043 0.28 ENST00000574218.1
CTNS
cystinosin, lysosomal cystine transporter
chr12_+_56732658 0.28 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr9_-_85882145 0.28 ENST00000328788.1
FRMD3
FERM domain containing 3
chr4_-_119759795 0.28 ENST00000419654.2
SEC24D
SEC24 family member D
chr18_-_46895066 0.28 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
DYM
dymeclin
chr13_-_30951282 0.27 ENST00000420219.1
LINC00426
long intergenic non-protein coding RNA 426
chr12_-_21910775 0.27 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr19_+_44617511 0.27 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr1_+_62439037 0.26 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr16_+_21623958 0.26 ENST00000568826.1
METTL9
methyltransferase like 9
chr15_-_44069513 0.26 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr7_+_120591170 0.25 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr2_-_61389240 0.24 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr17_+_80317121 0.24 ENST00000333437.4
TEX19
testis expressed 19
chr11_-_10920714 0.23 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr7_+_23637118 0.23 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chrX_+_53449887 0.23 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr19_+_41281060 0.22 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr1_-_67142710 0.22 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr3_+_190281229 0.22 ENST00000453359.1
IL1RAP
interleukin 1 receptor accessory protein
chr17_-_57229155 0.21 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr12_+_121570631 0.21 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr19_-_58204128 0.21 ENST00000597520.1
AC004017.1
Uncharacterized protein
chr1_+_162336686 0.20 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr19_-_51875894 0.20 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr6_-_32977345 0.19 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr8_+_118532937 0.19 ENST00000297347.3
MED30
mediator complex subunit 30
chr7_-_20826504 0.19 ENST00000418710.2
ENST00000361443.4
SP8
Sp8 transcription factor
chrX_-_54069576 0.19 ENST00000445025.1
ENST00000322659.8
PHF8
PHD finger protein 8
chr15_+_67458861 0.19 ENST00000558428.1
ENST00000558827.1
SMAD3
SMAD family member 3
chr9_-_127710292 0.19 ENST00000421514.1
GOLGA1
golgin A1
chr7_+_114055052 0.18 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr11_-_82745238 0.18 ENST00000531021.1
RAB30
RAB30, member RAS oncogene family
chr8_+_132320792 0.18 ENST00000519695.1
ENST00000524275.1
CTD-2501M5.1
CTD-2501M5.1
chr13_-_33780133 0.17 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_61389168 0.17 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
RP11-493E12.1
chr1_-_179834311 0.17 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr15_+_84116106 0.17 ENST00000535412.1
ENST00000324537.5
SH3GL3
SH3-domain GRB2-like 3
chr2_+_27799389 0.16 ENST00000408964.2
C2orf16
chromosome 2 open reading frame 16
chr16_+_2533020 0.16 ENST00000562105.1
TBC1D24
TBC1 domain family, member 24
chr11_-_26743546 0.16 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr6_-_138820624 0.16 ENST00000343505.5
NHSL1
NHS-like 1
chr11_+_5646213 0.15 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr1_-_242612779 0.15 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr19_+_50353944 0.15 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1
prostate tumor overexpressed 1
chr6_-_56492816 0.15 ENST00000522360.1
DST
dystonin
chr13_+_76362974 0.15 ENST00000497947.2
LMO7
LIM domain 7
chr8_-_133772870 0.15 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr1_-_54879140 0.15 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr3_-_195619579 0.15 ENST00000428187.1
TNK2
tyrosine kinase, non-receptor, 2
chr15_+_96876340 0.15 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_-_4754339 0.15 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr11_-_4629388 0.15 ENST00000526337.1
ENST00000300747.5
TRIM68
tripartite motif containing 68
chr1_-_152196669 0.14 ENST00000368801.2
HRNR
hornerin
chr9_+_2158485 0.14 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_159084188 0.14 ENST00000367081.3
SYTL3
synaptotagmin-like 3
chr6_+_99282570 0.14 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr12_-_31158902 0.14 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr20_-_1569278 0.14 ENST00000262929.5
ENST00000567028.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chr7_+_55980331 0.14 ENST00000429591.2
ZNF713
zinc finger protein 713
chr17_-_7218631 0.14 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2
G protein pathway suppressor 2
chr10_-_73497581 0.14 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr6_+_26440700 0.14 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr11_-_82746587 0.14 ENST00000528379.1
ENST00000534103.1
RAB30
RAB30, member RAS oncogene family
chr6_+_31949801 0.13 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr2_-_40657397 0.13 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_+_90192974 0.13 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr2_+_148602058 0.13 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr10_-_129924468 0.13 ENST00000368653.3
MKI67
marker of proliferation Ki-67
chr21_+_38593701 0.13 ENST00000440629.1
AP001432.14
AP001432.14
chr19_-_3761673 0.13 ENST00000316757.3
APBA3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr19_+_50354393 0.12 ENST00000391842.1
PTOV1
prostate tumor overexpressed 1
chr12_+_44229846 0.12 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr2_+_239335636 0.12 ENST00000409297.1
ASB1
ankyrin repeat and SOCS box containing 1
chr14_-_54425475 0.12 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr5_+_109025067 0.12 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chrX_-_54069253 0.12 ENST00000425862.1
ENST00000433120.1
PHF8
PHD finger protein 8
chr6_-_10412600 0.12 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_37225367 0.12 ENST00000336655.2
TMEM217
transmembrane protein 217
chr1_-_242612726 0.12 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr19_-_19302931 0.12 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B
MEF2BNB
MEF2B
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr9_+_2158443 0.12 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_25279759 0.12 ENST00000377969.3
LRRC16A
leucine rich repeat containing 16A
chr19_+_4402659 0.12 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr19_+_18303992 0.12 ENST00000599612.2
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr17_+_75449889 0.12 ENST00000590938.1
SEPT9
septin 9
chr7_+_16793160 0.12 ENST00000262067.4
TSPAN13
tetraspanin 13
chr16_+_2732476 0.12 ENST00000301738.4
ENST00000564195.1
KCTD5
potassium channel tetramerization domain containing 5
chr10_-_129924611 0.12 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr6_-_27835357 0.12 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr1_+_12524965 0.12 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr10_+_69869237 0.12 ENST00000373675.3
MYPN
myopalladin
chr18_+_56532100 0.12 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr17_-_36884451 0.12 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr12_-_118406028 0.12 ENST00000425217.1
KSR2
kinase suppressor of ras 2
chr19_+_36393422 0.12 ENST00000437550.2
HCST
hematopoietic cell signal transducer
chr17_-_45056606 0.12 ENST00000322329.3
RPRML
reprimo-like
chr20_-_62203808 0.12 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr5_-_150284351 0.12 ENST00000427179.1
ZNF300
zinc finger protein 300
chr12_+_113587558 0.12 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr17_+_61699766 0.12 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr7_-_37382360 0.12 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr17_-_1395954 0.12 ENST00000359786.5
MYO1C
myosin IC
chr17_+_4675175 0.11 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr17_+_44790515 0.11 ENST00000576346.1
NSF
N-ethylmaleimide-sensitive factor
chr1_+_203651937 0.11 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr9_+_2159850 0.11 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_+_75450099 0.11 ENST00000586433.1
SEPT9
septin 9
chr12_-_95510743 0.11 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr2_-_231989808 0.11 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_-_56595196 0.11 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4
myotubularin related protein 4
chr8_-_28965684 0.11 ENST00000523130.1
KIF13B
kinesin family member 13B
chr10_+_180405 0.11 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr17_+_5973740 0.11 ENST00000576083.1
WSCD1
WSC domain containing 1
chr9_+_70917276 0.11 ENST00000342833.2
FOXD4L3
forkhead box D4-like 3
chr19_-_55660561 0.11 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr3_-_188665428 0.11 ENST00000444488.1
TPRG1-AS1
TPRG1 antisense RNA 1
chr5_+_140529630 0.11 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr15_+_92396920 0.11 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr5_+_140729649 0.11 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr10_-_14996017 0.11 ENST00000378241.1
ENST00000456122.1
ENST00000418843.1
ENST00000378249.1
ENST00000396817.2
ENST00000378255.1
ENST00000378254.1
ENST00000378278.2
ENST00000357717.2
DCLRE1C
DNA cross-link repair 1C
chr4_+_41614720 0.11 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chrX_+_114874727 0.11 ENST00000543070.1
PLS3
plastin 3
chr13_+_76413852 0.11 ENST00000533809.2
LMO7
LIM domain 7
chr19_+_50354462 0.11 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chrX_-_73512177 0.11 ENST00000603672.1
ENST00000418855.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chrX_-_14047996 0.11 ENST00000380523.4
ENST00000398355.3
GEMIN8
gem (nuclear organelle) associated protein 8
chr15_+_99433570 0.11 ENST00000558898.1
IGF1R
insulin-like growth factor 1 receptor
chr7_+_45067265 0.11 ENST00000474617.1
CCM2
cerebral cavernous malformation 2
chr17_+_38337491 0.11 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr6_+_31795506 0.11 ENST00000375650.3
HSPA1B
heat shock 70kDa protein 1B
chr9_-_95244781 0.11 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr12_-_59314246 0.11 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr10_+_180643 0.11 ENST00000509513.2
ENST00000397959.3
ZMYND11
zinc finger, MYND-type containing 11
chr17_+_78518617 0.11 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr4_-_467892 0.10 ENST00000506646.1
ENST00000505900.1
ZNF721
zinc finger protein 721
chr10_+_47894023 0.10 ENST00000358474.5
FAM21B
family with sequence similarity 21, member B
chr2_+_101437487 0.10 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr12_-_4758159 0.10 ENST00000545990.2
AKAP3
A kinase (PRKA) anchor protein 3
chr2_+_238499812 0.10 ENST00000452801.1
AC104667.3
AC104667.3
chr19_+_44488330 0.10 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
ZNF155
zinc finger protein 155
chr1_+_201755452 0.10 ENST00000438083.1
NAV1
neuron navigator 1
chr18_+_55711575 0.10 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_+_31982539 0.10 ENST00000435363.2
ENST00000425700.2
C4B
complement component 4B (Chido blood group)
chr5_+_59783941 0.10 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr9_-_70178815 0.10 ENST00000377420.1
FOXD4L5
forkhead box D4-like 5
chr8_-_27115903 0.10 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr4_-_155533787 0.10 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr18_-_78005231 0.10 ENST00000470488.2
ENST00000353265.3
PARD6G
par-6 family cell polarity regulator gamma
chr19_-_43099070 0.10 ENST00000244336.5
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr4_+_86749045 0.10 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr11_-_11374904 0.10 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr6_+_30295036 0.10 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr1_+_104104379 0.10 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr2_-_37415690 0.10 ENST00000260637.3
ENST00000535679.1
ENST00000379149.2
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr19_-_18391708 0.09 ENST00000600972.1
JUND
jun D proto-oncogene
chrX_+_133507389 0.09 ENST00000370800.4
PHF6
PHD finger protein 6
chr19_+_41281282 0.09 ENST00000263369.3
MIA
melanoma inhibitory activity
chr1_+_23695680 0.09 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr17_+_75450146 0.09 ENST00000585929.1
ENST00000590917.1
SEPT9
septin 9
chr17_+_76311791 0.09 ENST00000586321.1
AC061992.2
AC061992.2
chr19_+_36393367 0.09 ENST00000246551.4
HCST
hematopoietic cell signal transducer
chr16_-_90038866 0.09 ENST00000314994.3
CENPBD1
CENPB DNA-binding domains containing 1
chr9_-_34376851 0.09 ENST00000297625.7
KIAA1161
KIAA1161
chr3_+_141106458 0.09 ENST00000509883.1
ZBTB38
zinc finger and BTB domain containing 38
chr17_+_1665253 0.09 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_+_117348742 0.09 ENST00000309909.5
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr22_+_27068704 0.09 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr20_+_58179582 0.09 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr20_+_36373032 0.09 ENST00000373473.1
CTNNBL1
catenin, beta like 1
chr12_+_57998400 0.09 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr22_-_42322795 0.09 ENST00000291232.3
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr12_+_100867486 0.09 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr17_-_40761375 0.09 ENST00000543197.1
ENST00000309428.5
FAM134C
family with sequence similarity 134, member C
chr16_-_18441131 0.09 ENST00000339303.5
NPIPA8
nuclear pore complex interacting protein family, member A8
chr6_+_37897735 0.09 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr17_-_62340581 0.09 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
TEX2
testis expressed 2
chr11_+_1889880 0.09 ENST00000405957.2
LSP1
lymphocyte-specific protein 1
chr11_-_59436453 0.09 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr3_+_40518599 0.09 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619
zinc finger protein 619
chr11_+_71900703 0.09 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr17_-_8093471 0.08 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr12_+_117176113 0.08 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr11_-_64703354 0.08 ENST00000532246.1
ENST00000279168.2
GPHA2
glycoprotein hormone alpha 2
chr1_-_150669604 0.08 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr17_+_40761660 0.08 ENST00000251413.3
ENST00000591509.1
TUBG1
tubulin, gamma 1
chr2_+_45168875 0.08 ENST00000260653.3
SIX3
SIX homeobox 3
chr10_-_91403625 0.08 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr1_+_236557569 0.08 ENST00000334232.4
EDARADD
EDAR-associated death domain
chr12_-_56843161 0.08 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
TIMELESS
timeless circadian clock

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.2 GO:0043132 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) NAD transport(GO:0043132)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.3 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:0098736 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0072099 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0032639 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0038185 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.0 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036457 keratohyalin granule(GO:0036457)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.0 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors