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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GLIS2

Z-value: 1.45

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Transcription factors associated with GLIS2

Gene Symbol Gene ID Gene Info
ENSG00000126603.4 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLIS2hg19_v2_chr16_+_4382225_4382225-0.355.0e-01Click!

Activity profile of GLIS2 motif

Sorted Z-values of GLIS2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615942 2.47 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr11_-_615570 2.11 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr17_+_41158742 1.57 ENST00000415816.2
ENST00000438323.2
interferon-induced protein 35
chr19_-_55669093 1.34 ENST00000344887.5
troponin I type 3 (cardiac)
chr20_-_62203808 1.23 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chr19_+_55795493 1.23 ENST00000309383.1
BR serine/threonine kinase 1
chr1_-_156675564 0.90 ENST00000368220.1
cellular retinoic acid binding protein 2
chr17_+_41177220 0.86 ENST00000587250.2
ENST00000544533.1
Rho family GTPase 2
chr11_-_627143 0.65 ENST00000176195.3
secretin
chr5_+_172484377 0.64 ENST00000523161.1
CREB3 regulatory factor
chr2_+_24272543 0.63 ENST00000380991.4
FK506 binding protein 1B, 12.6 kDa
chr1_-_27701307 0.63 ENST00000270879.4
ENST00000354982.2
ficolin (collagen/fibrinogen domain containing) 3
chr6_-_41673552 0.63 ENST00000419574.1
ENST00000445214.1
transcription factor EB
chr1_-_156675535 0.59 ENST00000368221.1
cellular retinoic acid binding protein 2
chr1_-_156675368 0.58 ENST00000368222.3
cellular retinoic acid binding protein 2
chr20_+_52824367 0.58 ENST00000371419.2
prefoldin subunit 4
chr2_-_27718052 0.57 ENST00000264703.3
fibronectin type III domain containing 4
chr19_-_6720686 0.54 ENST00000245907.6
complement component 3
chr19_-_821931 0.54 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chr3_-_52719888 0.53 ENST00000458294.1
polybromo 1
chr1_-_186649543 0.52 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_24272576 0.52 ENST00000380986.4
ENST00000452109.1
FK506 binding protein 1B, 12.6 kDa
chr1_-_54411255 0.48 ENST00000371377.3
heat shock protein family B (small), member 11
chr6_+_131571535 0.47 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr13_-_20767037 0.46 ENST00000382848.4
gap junction protein, beta 2, 26kDa
chr5_+_140566 0.46 ENST00000502646.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr9_+_139839686 0.45 ENST00000371634.2
complement component 8, gamma polypeptide
chr7_+_77167343 0.45 ENST00000433369.2
ENST00000415482.2
protein tyrosine phosphatase, non-receptor type 12
chr19_-_55668093 0.44 ENST00000588882.1
ENST00000586858.1
troponin I type 3 (cardiac)
chr9_+_139847347 0.42 ENST00000371632.3
lipocalin 12
chr8_-_103136481 0.41 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
neurocalcin delta
chr4_-_111120334 0.39 ENST00000503885.1
ELOVL fatty acid elongase 6
chr7_+_77167376 0.39 ENST00000435495.2
protein tyrosine phosphatase, non-receptor type 12
chr19_+_36602104 0.38 ENST00000585332.1
ENST00000262637.4
ovo-like zinc finger 3
chr17_-_41132088 0.38 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr19_-_51071302 0.38 ENST00000389201.3
ENST00000600381.1
leucine rich repeat containing 4B
chr1_-_31661000 0.38 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
Na+/K+ transporting ATPase interacting 1
chr12_-_120907374 0.37 ENST00000550458.1
serine/arginine-rich splicing factor 9
chr2_+_170655789 0.37 ENST00000409333.1
Sjogren syndrome antigen B (autoantigen La)
chr19_-_50979981 0.37 ENST00000595790.1
ENST00000600100.1
family with sequence similarity 71, member E1
chr14_-_24615523 0.36 ENST00000559056.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr21_-_45671014 0.36 ENST00000436357.1
DNA (cytosine-5-)-methyltransferase 3-like
chr5_-_131826457 0.36 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr2_+_48757278 0.36 ENST00000404752.1
ENST00000406226.1
stonin 1
chrX_+_53449805 0.35 ENST00000414955.2
RIB43A domain with coiled-coils 1
chrX_+_53449839 0.34 ENST00000457095.1
RIB43A domain with coiled-coils 1
chr20_-_30310797 0.34 ENST00000422920.1
BCL2-like 1
chr19_+_15619299 0.33 ENST00000269703.3
cytochrome P450, family 4, subfamily F, polypeptide 22
chr13_-_108867846 0.32 ENST00000442234.1
ligase IV, DNA, ATP-dependent
chr12_-_95942563 0.32 ENST00000549639.1
ENST00000551837.1
ubiquitin specific peptidase 44
chr3_+_118892411 0.32 ENST00000479520.1
ENST00000494855.1
uroplakin 1B
chr16_-_29910365 0.32 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr11_-_1619524 0.32 ENST00000412090.1
keratin associated protein 5-2
chr11_-_63684316 0.31 ENST00000301459.4
REST corepressor 2
chr1_-_54411240 0.30 ENST00000371378.2
heat shock protein family B (small), member 11
chr1_-_115632035 0.30 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
tetraspanin 2
chr5_+_68788594 0.30 ENST00000396442.2
ENST00000380766.2
occludin
chr19_+_56159421 0.30 ENST00000587213.1
coiled-coil domain containing 106
chr19_+_17858509 0.30 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1
chr14_-_54955376 0.30 ENST00000553333.1
glia maturation factor, beta
chr15_+_90234028 0.30 ENST00000268130.7
ENST00000560294.1
ENST00000558000.1
WD repeat domain 93
chr7_+_133812052 0.30 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr6_-_30815936 0.29 ENST00000442852.1
XXbac-BPG27H4.8
chr19_+_45417504 0.27 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr19_+_45349630 0.27 ENST00000252483.5
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr14_-_24615805 0.27 ENST00000560410.1
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_-_105635090 0.27 ENST00000331782.3
ENST00000347004.2
jagged 2
chr11_-_3013482 0.27 ENST00000529361.1
ENST00000528968.1
ENST00000534372.1
ENST00000531291.1
ENST00000526842.1
nucleosome assembly protein 1-like 4
chr17_-_7120525 0.27 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
discs, large homolog 4 (Drosophila)
chr1_-_6550625 0.26 ENST00000377725.1
ENST00000340850.5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_-_35454953 0.26 ENST00000404801.1
zinc finger protein 792
chr2_+_187350883 0.26 ENST00000337859.6
zinc finger CCCH-type containing 15
chr17_+_48503603 0.26 ENST00000502667.1
acyl-CoA synthetase family member 2
chr5_+_169011033 0.26 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr11_-_3013497 0.26 ENST00000448187.1
ENST00000532325.2
ENST00000399614.2
nucleosome assembly protein 1-like 4
chr6_+_144164455 0.25 ENST00000367576.5
LTV1 homolog (S. cerevisiae)
chr13_-_108867101 0.25 ENST00000356922.4
ligase IV, DNA, ATP-dependent
chr19_+_56159362 0.24 ENST00000593069.1
ENST00000308964.3
coiled-coil domain containing 106
chr2_+_71357744 0.24 ENST00000498451.2
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chrX_+_48660565 0.24 ENST00000413163.2
ENST00000441703.1
ENST00000426196.1
histone deacetylase 6
chr3_-_63849571 0.24 ENST00000295899.5
THO complex 7 homolog (Drosophila)
chr19_+_45349432 0.24 ENST00000252485.4
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr17_-_45266542 0.24 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
cell division cycle 27
chr8_+_27182862 0.24 ENST00000521164.1
ENST00000346049.5
protein tyrosine kinase 2 beta
chr19_+_56159509 0.24 ENST00000586790.1
ENST00000591578.1
ENST00000588740.1
coiled-coil domain containing 106
chr8_-_143833918 0.24 ENST00000359228.3
LY6/PLAUR domain containing 2
chr5_+_169659950 0.24 ENST00000593851.1
chromosome 5 open reading frame 58
chr1_-_151138422 0.24 ENST00000440902.2
LysM, putative peptidoglycan-binding, domain containing 1
chr1_+_43424698 0.23 ENST00000431759.1
SLC2A1 antisense RNA 1
chr11_-_3013316 0.23 ENST00000430811.1
nucleosome assembly protein 1-like 4
chr4_-_111120132 0.23 ENST00000506625.1
ELOVL fatty acid elongase 6
chr17_+_48503519 0.23 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
acyl-CoA synthetase family member 2
chr11_-_117688216 0.23 ENST00000525836.1
Down syndrome cell adhesion molecule like 1
chr13_-_95248511 0.23 ENST00000261296.5
TDP-glucose 4,6-dehydratase
chr19_+_45417812 0.22 ENST00000592535.1
apolipoprotein C-I
chr2_-_113999260 0.22 ENST00000468980.2
paired box 8
chr8_+_27183033 0.22 ENST00000420218.2
protein tyrosine kinase 2 beta
chr17_+_30348024 0.22 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
leucine rich repeat containing 37B
chr4_-_170679024 0.22 ENST00000393381.2
chromosome 4 open reading frame 27
chr6_+_43044003 0.21 ENST00000230419.4
ENST00000476760.1
ENST00000471863.1
ENST00000349241.2
ENST00000352931.2
ENST00000345201.2
protein tyrosine kinase 7
chr22_-_30661807 0.21 ENST00000403389.1
oncostatin M
chr2_-_157186630 0.21 ENST00000406048.2
nuclear receptor subfamily 4, group A, member 2
chr19_-_3772209 0.21 ENST00000555978.1
ENST00000555633.1
retina and anterior neural fold homeobox 2
chr3_+_151531859 0.21 ENST00000488869.1
arylacetamide deacetylase
chr19_+_45251804 0.21 ENST00000164227.5
B-cell CLL/lymphoma 3
chr20_-_30310693 0.21 ENST00000307677.4
ENST00000420653.1
BCL2-like 1
chrX_+_53449887 0.21 ENST00000375327.3
RIB43A domain with coiled-coils 1
chr9_+_135285579 0.20 ENST00000343036.2
ENST00000393216.2
chromosome 9 open reading frame 171
chr4_-_106394866 0.20 ENST00000502596.1
pyrophosphatase (inorganic) 2
chr10_+_115438920 0.20 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr18_+_56531584 0.20 ENST00000590287.1
zinc finger protein 532
chr17_-_4463856 0.20 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr14_-_21493884 0.20 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr14_+_103566481 0.20 ENST00000380069.3
exocyst complex component 3-like 4
chr8_-_104427289 0.20 ENST00000543107.1
solute carrier family 25 (mitochondrial folate carrier), member 32
chr15_+_63796779 0.19 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
ubiquitin specific peptidase 3
chr20_-_30310656 0.19 ENST00000376055.4
BCL2-like 1
chr6_-_117086873 0.19 ENST00000368557.4
family with sequence similarity 162, member B
chr17_-_79166176 0.19 ENST00000571292.1
5-azacytidine induced 1
chr14_-_50999307 0.19 ENST00000013125.4
mitogen-activated protein kinase kinase kinase kinase 5
chr6_-_114292449 0.19 ENST00000519065.1
histone deacetylase 2
chr19_+_45417921 0.19 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr22_+_22681656 0.19 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr19_-_2282167 0.19 ENST00000342063.3
chromosome 19 open reading frame 35
chr3_-_49933249 0.18 ENST00000434765.1
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr6_-_114292284 0.18 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr11_+_61197508 0.18 ENST00000541135.1
ENST00000301761.2
Uncharacterized protein
succinate dehydrogenase complex assembly factor 2
chr8_-_95565673 0.18 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429
chr5_+_102090974 0.18 ENST00000512073.1
peptidylglycine alpha-amidating monooxygenase
chrX_+_102631844 0.18 ENST00000372634.1
ENST00000299872.7
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_91966384 0.18 ENST00000430031.2
ENST00000234626.6
cell division cycle 7
chrX_-_48823165 0.18 ENST00000419374.1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_-_14586125 0.17 ENST00000292513.3
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr14_-_92302784 0.17 ENST00000340892.5
ENST00000360594.5
tandem C2 domains, nuclear
chr12_-_51422017 0.17 ENST00000394904.3
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr19_-_17799008 0.17 ENST00000519716.2
unc-13 homolog A (C. elegans)
chr12_+_56401268 0.17 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr8_+_38243967 0.17 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
leucine zipper-EF-hand containing transmembrane protein 2
chr11_-_111637083 0.17 ENST00000427203.2
ENST00000341980.6
ENST00000311129.5
ENST00000393055.2
ENST00000426998.2
ENST00000527614.1
protein phosphatase 2, regulatory subunit A, beta
chr16_-_29910853 0.17 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr12_-_95467267 0.17 ENST00000330677.7
nuclear receptor subfamily 2, group C, member 1
chr14_+_101293687 0.17 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr12_-_95942613 0.17 ENST00000393091.2
ubiquitin specific peptidase 44
chr12_+_50451462 0.17 ENST00000447966.2
acid-sensing (proton-gated) ion channel 1
chr1_-_156647189 0.16 ENST00000368223.3
nestin
chr19_+_7413835 0.16 ENST00000576789.1
CTB-133G6.1
chr20_-_30458019 0.16 ENST00000486996.1
ENST00000398084.2
dual specificity phosphatase 15
chr3_+_111578131 0.16 ENST00000498699.1
pleckstrin homology-like domain, family B, member 2
chr12_-_95467356 0.16 ENST00000393101.3
ENST00000333003.5
nuclear receptor subfamily 2, group C, member 1
chr17_-_40169429 0.16 ENST00000316603.7
ENST00000588641.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr18_+_12948000 0.16 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr17_+_18012020 0.15 ENST00000205890.5
myosin XVA
chr3_-_49933506 0.15 ENST00000440292.1
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr11_-_46142615 0.15 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr1_-_40157345 0.15 ENST00000372844.3
hippocalcin like 4
chr17_-_4269768 0.15 ENST00000396981.2
ubiquitin-conjugating enzyme E2G 1
chr1_+_64936428 0.15 ENST00000371073.2
ENST00000290039.5
cache domain containing 1
chr19_-_17185848 0.15 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr1_+_150954493 0.15 ENST00000368947.4
annexin A9
chr6_-_153304697 0.15 ENST00000367241.3
F-box protein 5
chr2_+_29033682 0.15 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
speedy/RINGO cell cycle regulator family member A
chr2_-_220197351 0.15 ENST00000392083.1
regulated endocrine-specific protein 18
chr1_+_87595497 0.15 ENST00000471417.1
long intergenic non-protein coding RNA 1140
chr3_+_52719936 0.15 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr15_+_52311398 0.15 ENST00000261845.5
mitogen-activated protein kinase 6
chr11_-_14665163 0.15 ENST00000418988.2
proteasome (prosome, macropain) subunit, alpha type, 1
chr17_-_40169161 0.14 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr8_+_38243951 0.14 ENST00000297720.5
leucine zipper-EF-hand containing transmembrane protein 2
chr5_+_149865377 0.14 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_+_181845074 0.14 ENST00000602959.1
ENST00000602479.1
ENST00000392415.2
ENST00000602291.1
ubiquitin-conjugating enzyme E2E 3
chr2_+_89952792 0.14 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr22_-_38794490 0.14 ENST00000400206.2
casein kinase 1, epsilon
chr17_-_36760865 0.14 ENST00000584266.1
SRC kinase signaling inhibitor 1
chr12_-_51785182 0.14 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr8_+_38243821 0.14 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr7_-_158380371 0.14 ENST00000389418.4
ENST00000389416.4
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr22_-_50700140 0.14 ENST00000215659.8
mitogen-activated protein kinase 12
chr6_-_153304148 0.13 ENST00000229758.3
F-box protein 5
chr22_-_30685596 0.13 ENST00000404953.3
ENST00000407689.3
GATS protein-like 3
chr10_+_94608245 0.13 ENST00000443748.2
ENST00000260762.6
exocyst complex component 6
chr6_-_32908792 0.13 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr3_-_128840604 0.13 ENST00000476465.1
ENST00000315150.5
ENST00000393304.1
ENST00000393308.1
ENST00000393307.1
ENST00000393305.1
RAB43, member RAS oncogene family
chr17_-_79623597 0.13 ENST00000574024.1
ENST00000331056.5
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr16_+_2198604 0.13 ENST00000210187.6
RAB26, member RAS oncogene family
chr14_-_21493649 0.13 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr3_+_151531810 0.13 ENST00000232892.7
arylacetamide deacetylase
chr8_+_118533049 0.13 ENST00000522839.1
mediator complex subunit 30
chr2_+_37571717 0.13 ENST00000338415.3
ENST00000404976.1
glutaminyl-peptide cyclotransferase
chr19_-_2702681 0.13 ENST00000382159.3
guanine nucleotide binding protein (G protein), gamma 7
chr1_+_43637996 0.13 ENST00000528956.1
ENST00000529956.1
WD repeat domain 65
chr1_-_22215192 0.13 ENST00000374673.3
heparan sulfate proteoglycan 2
chr1_+_65613217 0.13 ENST00000545314.1
adenylate kinase 4
chr3_-_43663519 0.12 ENST00000427171.1
ENST00000292246.3
anoctamin 10
chr18_-_19180681 0.12 ENST00000269214.5
establishment of sister chromatid cohesion N-acetyltransferase 1
chr3_+_180630444 0.12 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
fragile X mental retardation, autosomal homolog 1
chr12_+_50017327 0.12 ENST00000261897.1
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_-_39108568 0.12 ENST00000586296.1
mitogen-activated protein kinase kinase kinase kinase 1
chr17_+_64831228 0.12 ENST00000533854.1
calcium channel, voltage-dependent, gamma subunit 5
chr1_+_47901689 0.12 ENST00000334793.5
forkhead box D2
chr7_+_130794846 0.12 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 0.6 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.2 0.6 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.2 0.5 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 2.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 1.9 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.1 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.5 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.5 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:1903911 positive regulation of receptor clustering(GO:1903911)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.2 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.3 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.6 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.4 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 1.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.0 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.0 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363) discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0030172 troponin C binding(GO:0030172)
0.2 1.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 2.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.5 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.3 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 4.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions