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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HBP1

Z-value: 0.73

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
HBP1
ENSG00000105856.9 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg19_v2_chr7_+_106810165_106810374-0.621.9e-01Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_77246337 0.93 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr12_+_122018697 0.45 ENST00000541574.1
RP13-941N14.1
RP13-941N14.1
chr7_-_2354099 0.34 ENST00000222990.3
SNX8
sorting nexin 8
chr1_+_85527987 0.32 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr19_-_10697895 0.32 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_-_25291475 0.32 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr17_+_36584662 0.32 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr19_+_18794470 0.29 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr2_+_87808725 0.29 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr12_-_89746264 0.28 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr5_+_156887027 0.28 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr22_+_41968007 0.27 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr6_-_30640761 0.27 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr16_+_57769635 0.25 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr8_+_66619277 0.24 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chr19_-_10305752 0.24 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr9_-_128246769 0.24 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_29874341 0.24 ENST00000409290.1
ENST00000242140.5
WIPF3
WAS/WASL interacting protein family, member 3
chr19_-_3500635 0.24 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr17_+_75369400 0.24 ENST00000590059.1
SEPT9
septin 9
chr3_-_87039662 0.23 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr4_+_174818390 0.23 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
RP11-161D15.1
chr6_-_30640811 0.22 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr22_+_22988816 0.22 ENST00000480559.1
ENST00000448514.1
GGTLC2
gamma-glutamyltransferase light chain 2
chr11_+_66824276 0.22 ENST00000308831.2
RHOD
ras homolog family member D
chr5_-_147211226 0.22 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr1_-_151319654 0.21 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr6_+_149539053 0.21 ENST00000451095.1
RP1-111D6.3
RP1-111D6.3
chr9_+_116207007 0.21 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr15_+_75074410 0.21 ENST00000439220.2
CSK
c-src tyrosine kinase
chr7_+_65540853 0.20 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr18_-_56985776 0.20 ENST00000587244.1
CPLX4
complexin 4
chr17_-_42327236 0.20 ENST00000399246.2
AC003102.1
AC003102.1
chrX_+_2746818 0.20 ENST00000398806.3
GYG2
glycogenin 2
chr12_-_58027138 0.20 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chrX_+_100075368 0.20 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr15_-_54267147 0.20 ENST00000558866.1
ENST00000558920.1
RP11-643A5.2
RP11-643A5.2
chr2_-_220264703 0.19 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr14_+_102430855 0.19 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr22_-_22337204 0.19 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr22_-_22337154 0.19 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr15_+_75074385 0.19 ENST00000220003.9
CSK
c-src tyrosine kinase
chr16_-_3661578 0.19 ENST00000294008.3
SLX4
SLX4 structure-specific endonuclease subunit
chr20_-_56286479 0.19 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chrX_+_18725758 0.19 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr15_-_86338134 0.19 ENST00000337975.5
KLHL25
kelch-like family member 25
chr5_-_140070897 0.18 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr2_-_197226875 0.18 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr19_-_54579813 0.18 ENST00000446034.2
TARM1
T cell-interacting, activating receptor on myeloid cells 1
chr2_-_239149300 0.18 ENST00000436051.1
HES6
hes family bHLH transcription factor 6
chr22_-_22337146 0.18 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr12_-_11139511 0.18 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr3_-_127455200 0.18 ENST00000398101.3
MGLL
monoglyceride lipase
chr19_-_56092187 0.17 ENST00000325421.4
ENST00000592239.1
ZNF579
zinc finger protein 579
chr2_-_157189180 0.17 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_20850813 0.17 ENST00000402541.1
ENST00000406618.3
ENST00000304031.3
HS1BP3
HCLS1 binding protein 3
chr3_-_52090461 0.17 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr16_-_67217844 0.17 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr8_+_63161491 0.17 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr22_-_20367797 0.17 ENST00000424787.2
GGTLC3
gamma-glutamyltransferase light chain 3
chr7_-_83278322 0.16 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr22_+_24236191 0.16 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr1_+_113392455 0.16 ENST00000456651.1
ENST00000422022.1
RP3-522D1.1
RP3-522D1.1
chr19_+_19144384 0.16 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr1_-_24126892 0.16 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr2_+_65663812 0.16 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr3_+_184032419 0.16 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr11_+_73087309 0.16 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr7_-_5821314 0.16 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr7_-_149158187 0.16 ENST00000247930.4
ZNF777
zinc finger protein 777
chr11_-_66725837 0.16 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr17_+_75369167 0.15 ENST00000423034.2
SEPT9
septin 9
chr5_+_140514782 0.15 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr19_-_45927097 0.15 ENST00000340192.7
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr20_-_33872548 0.15 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr11_+_20044096 0.15 ENST00000533917.1
NAV2
neuron navigator 2
chr12_-_53320245 0.15 ENST00000552150.1
KRT8
keratin 8
chr3_+_126423045 0.15 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr5_+_159656437 0.15 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr12_-_121972556 0.15 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr19_-_45927622 0.14 ENST00000300853.3
ENST00000589165.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr20_-_30458432 0.14 ENST00000375966.4
ENST00000278979.3
DUSP15
dual specificity phosphatase 15
chr7_-_130080977 0.14 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr15_-_40633101 0.14 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr1_+_110577229 0.14 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr6_-_44233361 0.14 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr10_+_24528108 0.14 ENST00000438429.1
KIAA1217
KIAA1217
chr16_-_745946 0.14 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr1_-_27693349 0.14 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr19_+_41698927 0.14 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr7_+_99070464 0.14 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
ZNF789
zinc finger protein 789
chr19_+_34855925 0.14 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr20_+_25176450 0.14 ENST00000425813.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr1_+_240255166 0.13 ENST00000319653.9
FMN2
formin 2
chr19_+_34856078 0.13 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr1_-_113392399 0.13 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8
RP11-426L16.8
chr16_-_28223166 0.13 ENST00000304658.5
XPO6
exportin 6
chr17_-_41856305 0.13 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr20_-_33543546 0.13 ENST00000216951.2
GSS
glutathione synthetase
chr11_+_66824346 0.13 ENST00000532559.1
RHOD
ras homolog family member D
chr19_-_39390440 0.13 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr1_-_155826967 0.13 ENST00000368331.1
ENST00000361040.5
ENST00000271883.5
GON4L
gon-4-like (C. elegans)
chr11_+_69061594 0.13 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr9_+_127624387 0.13 ENST00000353214.2
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr19_+_34856141 0.13 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr16_+_11762270 0.13 ENST00000329565.5
SNN
stannin
chr11_+_63742050 0.13 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr19_-_38806560 0.13 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr8_-_27457494 0.13 ENST00000521770.1
CLU
clusterin
chr17_-_27405875 0.13 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr5_+_149737202 0.12 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr6_+_29555683 0.12 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr3_+_184032313 0.12 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_44435646 0.12 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2
DPH2 homolog (S. cerevisiae)
chr14_+_88471468 0.12 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr15_+_57891609 0.12 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr1_-_17338267 0.12 ENST00000326735.8
ATP13A2
ATPase type 13A2
chr5_+_175223313 0.12 ENST00000359546.4
CPLX2
complexin 2
chr2_-_239148599 0.12 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chrX_+_54834159 0.11 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr8_+_22019168 0.11 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr19_-_42806723 0.11 ENST00000262890.3
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr2_+_65216462 0.11 ENST00000234256.3
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr19_-_39390350 0.11 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr17_+_8152590 0.11 ENST00000584044.1
ENST00000314666.6
ENST00000545834.1
ENST00000581242.1
PFAS
phosphoribosylformylglycinamidine synthase
chr3_+_184032283 0.11 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_-_58146128 0.11 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr19_+_34855874 0.11 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr17_-_36904437 0.11 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr8_-_8751068 0.11 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr6_-_41909561 0.11 ENST00000372991.4
CCND3
cyclin D3
chr9_+_133589333 0.11 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr1_+_200860122 0.11 ENST00000532631.1
ENST00000451872.2
C1orf106
chromosome 1 open reading frame 106
chr6_+_30297306 0.11 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr8_-_27850141 0.11 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr8_-_116504448 0.11 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_+_125985620 0.11 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr2_+_231902193 0.11 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr20_+_25176318 0.11 ENST00000354989.5
ENST00000360031.2
ENST00000376652.4
ENST00000439162.1
ENST00000433417.1
ENST00000417467.1
ENST00000433259.2
ENST00000427553.1
ENST00000435520.1
ENST00000418890.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr7_+_65540780 0.11 ENST00000304874.9
ASL
argininosuccinate lyase
chr7_-_56101826 0.11 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr12_+_123868320 0.10 ENST00000402868.3
ENST00000330479.4
SETD8
SET domain containing (lysine methyltransferase) 8
chr20_+_10415931 0.10 ENST00000334534.5
SLX4IP
SLX4 interacting protein
chr22_-_20368028 0.10 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr19_+_39390587 0.10 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_+_242498135 0.10 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr19_-_38806540 0.10 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr14_+_78266408 0.10 ENST00000238561.5
ADCK1
aarF domain containing kinase 1
chr20_-_39928705 0.10 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
ZHX3
zinc fingers and homeoboxes 3
chr18_+_18943554 0.10 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr1_-_85930246 0.10 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_+_148521136 0.10 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chrY_+_4868267 0.10 ENST00000333703.4
PCDH11Y
protocadherin 11 Y-linked
chr5_+_148521454 0.10 ENST00000508983.1
ABLIM3
actin binding LIM protein family, member 3
chr1_-_151319710 0.10 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr2_-_190448118 0.10 ENST00000440626.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_65730385 0.10 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_+_131217459 0.10 ENST00000497812.2
ENST00000393533.2
ODF2
outer dense fiber of sperm tails 2
chr5_+_140071011 0.10 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chrX_+_54834004 0.10 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr5_+_148521381 0.10 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr19_-_18654828 0.09 ENST00000609656.1
ENST00000597611.3
FKBP8
FK506 binding protein 8, 38kDa
chr20_-_39928756 0.09 ENST00000432768.2
ZHX3
zinc fingers and homeoboxes 3
chr1_+_145209092 0.09 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr22_-_30956746 0.09 ENST00000437282.1
ENST00000447224.1
ENST00000427899.1
ENST00000406955.1
ENST00000452827.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr4_-_175041663 0.09 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr16_+_57139933 0.09 ENST00000566259.1
CPNE2
copine II
chr19_-_19144243 0.09 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr21_+_45138941 0.09 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_-_47574664 0.09 ENST00000310513.5
ENST00000531165.1
CELF1
CUGBP, Elav-like family member 1
chr12_-_124118296 0.09 ENST00000424014.2
ENST00000537073.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr19_-_39390212 0.09 ENST00000437828.1
SIRT2
sirtuin 2
chr16_-_30905584 0.09 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr17_+_6918093 0.08 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr2_+_235887329 0.08 ENST00000409212.1
ENST00000344528.4
ENST00000444916.1
SH3BP4
SH3-domain binding protein 4
chr9_-_35563896 0.08 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr6_-_41909466 0.08 ENST00000414200.2
CCND3
cyclin D3
chr11_+_57435219 0.08 ENST00000527985.1
ENST00000287169.3
ZDHHC5
zinc finger, DHHC-type containing 5
chr19_+_3506261 0.08 ENST00000441788.2
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr12_-_122018859 0.08 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B
lysine (K)-specific demethylase 2B
chr8_+_23104130 0.08 ENST00000313219.7
ENST00000519984.1
CHMP7
charged multivesicular body protein 7
chr11_+_94277017 0.08 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr17_-_1588101 0.08 ENST00000577001.1
ENST00000572621.1
ENST00000304992.6
PRPF8
pre-mRNA processing factor 8
chr12_+_128399965 0.08 ENST00000540882.1
ENST00000542089.1
LINC00507
long intergenic non-protein coding RNA 507
chr12_-_124118151 0.08 ENST00000534960.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr19_+_1040096 0.08 ENST00000263094.6
ENST00000524850.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr20_-_33872518 0.08 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr1_-_16563641 0.08 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr20_+_18125727 0.08 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr11_-_65667884 0.08 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr1_-_31769595 0.07 ENST00000263694.4
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr5_-_22853429 0.07 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr20_-_48747662 0.07 ENST00000371656.2
TMEM189
transmembrane protein 189
chrX_+_36254051 0.07 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr19_+_39390320 0.07 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_-_19746236 0.07 ENST00000375144.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr16_+_15596123 0.07 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr19_-_42806919 0.07 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr6_+_30614779 0.07 ENST00000293604.6
ENST00000376473.5
C6orf136
chromosome 6 open reading frame 136
chr19_-_45657028 0.07 ENST00000429338.1
ENST00000589776.1
NKPD1
NTPase, KAP family P-loop domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.2 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.1 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.0 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.5 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.2 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.2 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.2 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling