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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMGA1

Z-value: 1.55

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Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
HMGA1
ENSG00000137309.15 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg19_v2_chr6_+_34204642_34204664-0.731.0e-01Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_35013217 2.38 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr8_-_90993869 1.90 ENST00000517772.1
NBN
nibrin
chr12_+_20963647 1.69 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr3_-_148939598 1.59 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr7_-_81635106 1.57 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr14_+_61449197 1.52 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr12_-_100656134 1.44 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr1_+_196621002 1.36 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr3_+_164924716 1.32 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
RP11-85M11.2
chr1_+_95616933 1.29 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr21_+_35553045 1.28 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr12_+_20963632 1.26 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_+_78804393 1.22 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr6_-_56492816 1.13 ENST00000522360.1
DST
dystonin
chr9_-_3469181 1.09 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr9_-_70465758 1.07 ENST00000489273.1
CBWD5
COBW domain containing 5
chr4_-_155533787 1.03 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr4_-_164265984 1.02 ENST00000511901.1
NPY1R
neuropeptide Y receptor Y1
chr5_-_87516448 1.01 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr1_+_196621156 1.00 ENST00000359637.2
CFH
complement factor H
chr4_+_55095428 0.95 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_162101247 0.93 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr12_+_41136144 0.89 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr10_+_94590910 0.88 ENST00000371547.4
EXOC6
exocyst complex component 6
chr10_+_94594351 0.85 ENST00000371552.4
EXOC6
exocyst complex component 6
chr4_+_155484155 0.82 ENST00000509493.1
FGB
fibrinogen beta chain
chr2_-_165630264 0.81 ENST00000452626.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr2_-_202298268 0.81 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr12_+_65996599 0.80 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr14_+_73563735 0.76 ENST00000532192.1
RBM25
RNA binding motif protein 25
chrX_-_20237059 0.76 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_+_151358048 0.76 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr14_+_58797974 0.76 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr1_+_219347186 0.74 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr3_+_136649311 0.73 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr12_-_91546926 0.72 ENST00000550758.1
DCN
decorin
chr2_-_187367356 0.72 ENST00000595956.1
AC018867.2
AC018867.2
chr1_+_186265399 0.69 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr1_+_219347203 0.69 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr12_-_102591604 0.68 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr2_+_29001711 0.68 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr8_+_107738240 0.66 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr5_-_43515125 0.66 ENST00000509489.1
C5orf34
chromosome 5 open reading frame 34
chr5_+_40841410 0.63 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr1_-_108231101 0.62 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr6_+_12008986 0.61 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr12_+_9144626 0.60 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr3_-_122102065 0.59 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
CCDC58
coiled-coil domain containing 58
chr5_+_158737824 0.59 ENST00000521472.1
AC008697.1
AC008697.1
chr6_-_106773610 0.58 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr2_-_228244013 0.58 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr2_+_145780739 0.58 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr7_-_92777606 0.57 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr9_-_47314222 0.56 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr14_+_57671888 0.56 ENST00000391612.1
AL391152.1
AL391152.1
chr9_-_69229650 0.56 ENST00000416428.1
CBWD6
COBW domain containing 6
chrX_-_20236970 0.55 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_56078695 0.54 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chrY_+_14958970 0.54 ENST00000453031.1
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr17_-_64216748 0.53 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr15_+_71228826 0.53 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr8_+_107738343 0.53 ENST00000521592.1
OXR1
oxidation resistance 1
chr1_-_86848760 0.52 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr3_+_171561127 0.52 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr5_+_68513622 0.52 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr13_+_76378305 0.52 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr1_+_207943667 0.52 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein
chr1_+_92632542 0.51 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr2_+_145780725 0.51 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr7_+_116502605 0.51 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr4_-_159080806 0.50 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr8_-_123706338 0.50 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr5_-_43515231 0.50 ENST00000306862.2
C5orf34
chromosome 5 open reading frame 34
chr6_-_10115007 0.49 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr10_+_32856764 0.49 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr18_+_20494078 0.48 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr9_-_104145795 0.48 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr2_+_64069459 0.48 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr11_+_17316870 0.48 ENST00000458064.2
NUCB2
nucleobindin 2
chr17_-_39341594 0.48 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr15_+_35270552 0.48 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr16_+_53241854 0.48 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_+_141294628 0.48 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
SCOC
short coiled-coil protein
chr15_+_63188009 0.47 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_+_145780767 0.47 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr2_+_114195268 0.46 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr3_-_148939835 0.46 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr13_-_49975632 0.45 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr19_-_44384291 0.45 ENST00000324394.6
ZNF404
zinc finger protein 404
chr1_+_78470530 0.45 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chrM_+_8527 0.45 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr2_+_103378472 0.45 ENST00000412401.2
TMEM182
transmembrane protein 182
chr9_+_86595626 0.44 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr10_-_102045882 0.44 ENST00000579542.1
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr11_-_111781554 0.44 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr14_+_39703084 0.44 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr3_-_107596910 0.44 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr4_+_95128996 0.43 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr12_-_54653313 0.43 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr15_+_77713222 0.43 ENST00000558176.1
HMG20A
high mobility group 20A
chr5_+_68860949 0.43 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr6_+_153552455 0.42 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr2_-_87248975 0.42 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr4_+_90033968 0.42 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr17_+_70036164 0.42 ENST00000602013.1
AC007461.1
Uncharacterized protein
chr4_+_95129061 0.42 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_+_142342228 0.42 ENST00000337777.3
PLS1
plastin 1
chr5_-_54988448 0.42 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr4_+_109571740 0.42 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr14_+_102276209 0.41 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr5_-_41794663 0.41 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr14_+_56127989 0.41 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr6_+_145118873 0.41 ENST00000432686.1
ENST00000417142.1
UTRN
utrophin
chr10_-_36812323 0.41 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr7_+_36450169 0.40 ENST00000428612.1
ANLN
anillin, actin binding protein
chr15_+_55611401 0.40 ENST00000566999.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr1_-_197169672 0.40 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr15_-_80263506 0.40 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr12_-_91505608 0.39 ENST00000266718.4
LUM
lumican
chr3_-_149510553 0.39 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr16_-_66907139 0.39 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr1_+_90098606 0.38 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr1_-_220219775 0.37 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr2_+_29353520 0.37 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr17_-_39183452 0.37 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr12_+_28410128 0.37 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr1_-_28384598 0.37 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr1_+_89246647 0.37 ENST00000544045.1
PKN2
protein kinase N2
chr2_+_105050794 0.36 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr5_+_158690089 0.36 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr14_+_45366472 0.36 ENST00000325192.3
C14orf28
chromosome 14 open reading frame 28
chr9_-_115095123 0.36 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr1_+_204494618 0.36 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr3_+_135684515 0.35 ENST00000264977.3
ENST00000490467.1
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr2_-_225434538 0.35 ENST00000409096.1
CUL3
cullin 3
chr8_+_107593198 0.35 ENST00000517686.1
OXR1
oxidation resistance 1
chr4_+_144303093 0.35 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr14_+_67831576 0.35 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr12_+_21284118 0.35 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chrX_-_138914394 0.35 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr8_+_104426942 0.34 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr14_+_62164340 0.34 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr1_-_169555779 0.34 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr1_+_186798073 0.34 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr4_+_74301880 0.34 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr7_-_120498357 0.34 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr12_-_10588539 0.34 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr2_+_191792376 0.33 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr1_-_101360331 0.33 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr3_-_196910477 0.33 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr17_-_80797886 0.33 ENST00000572562.1
ZNF750
zinc finger protein 750
chr13_+_97928395 0.32 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr12_-_8765446 0.32 ENST00000537228.1
ENST00000229335.6
AICDA
activation-induced cytidine deaminase
chr5_+_118691008 0.32 ENST00000504642.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr2_-_99279928 0.32 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr8_-_66701319 0.32 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr5_-_75008244 0.32 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr1_+_156308403 0.32 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr4_-_105416039 0.32 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr14_+_39736582 0.32 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr1_-_59165763 0.32 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr7_+_141478242 0.32 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr1_+_52082751 0.32 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr2_+_162016804 0.31 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr6_+_76311568 0.31 ENST00000370014.3
SENP6
SUMO1/sentrin specific peptidase 6
chr3_-_121448791 0.31 ENST00000489400.1
GOLGB1
golgin B1
chr2_+_86333340 0.31 ENST00000409783.2
ENST00000409277.3
PTCD3
pentatricopeptide repeat domain 3
chr5_+_138678131 0.31 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr1_-_89591749 0.31 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr16_+_53412368 0.31 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr12_+_110718428 0.30 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr13_+_33160553 0.30 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr10_-_21661870 0.30 ENST00000433460.1
RP11-275N1.1
RP11-275N1.1
chr13_-_31039375 0.30 ENST00000399494.1
HMGB1
high mobility group box 1
chr4_-_143227088 0.30 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_-_130080681 0.30 ENST00000469826.1
CEP41
centrosomal protein 41kDa
chr3_-_98241713 0.30 ENST00000502288.1
ENST00000512147.1
ENST00000510541.1
ENST00000503621.1
ENST00000511081.1
CLDND1
claudin domain containing 1
chr15_+_80364901 0.30 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
ZFAND6
zinc finger, AN1-type domain 6
chr9_-_123812542 0.30 ENST00000223642.1
C5
complement component 5
chr1_-_115124257 0.30 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr4_-_70725856 0.28 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr12_+_14572070 0.28 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr13_+_28813645 0.28 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_53528659 0.28 ENST00000350061.5
CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_-_179914760 0.28 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr11_-_2906979 0.28 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr1_+_81771806 0.28 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr3_+_107364769 0.28 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr3_+_130648842 0.28 ENST00000508297.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr10_-_69597828 0.28 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chrX_-_77150985 0.28 ENST00000358075.6
MAGT1
magnesium transporter 1
chr3_+_107364683 0.28 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr5_-_39270725 0.27 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr2_+_86333301 0.27 ENST00000254630.7
PTCD3
pentatricopeptide repeat domain 3
chr22_-_40929812 0.27 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_-_35182994 0.27 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr13_+_108870714 0.27 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr14_-_82000140 0.27 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr4_+_155484103 0.27 ENST00000302068.4
FGB
fibrinogen beta chain
chr6_-_52859046 0.26 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 0.8 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 0.7 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 2.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.6 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.2 1.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2 0.2 GO:0060143 regulation of syncytium formation by plasma membrane fusion(GO:0060142) positive regulation of syncytium formation by plasma membrane fusion(GO:0060143)
0.2 1.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 2.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.4 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 1.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.3 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.7 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.2 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.1 1.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.3 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.1 0.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.2 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.5 GO:0019530 taurine metabolic process(GO:0019530)
0.0 1.3 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.5 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0061508 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:1901660 cellular response to corticosterone stimulus(GO:0071386) calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0022605 ovarian cumulus expansion(GO:0001550) oogenesis stage(GO:0022605) fused antrum stage(GO:0048165)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:1903286 regulation of potassium ion import(GO:1903286)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0031673 H zone(GO:0031673)
0.1 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.9 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 1.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 4.7 GO:0072562 blood microparticle(GO:0072562)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.3 1.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.3 2.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.2 0.6 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.2 0.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.5 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.4 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.4 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 2.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.2 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.1 0.2 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.3 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.1 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 1.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.3 PID INSULIN PATHWAY Insulin Pathway
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes