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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX3

Z-value: 1.27

Motif logo

Transcription factors associated with HMX3

Gene Symbol Gene ID Gene Info
ENSG00000188620.9 H6 family homeobox 3

Activity profile of HMX3 motif

Sorted Z-values of HMX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_101349823 1.91 ENST00000519566.1
KB-1991G8.1
chr17_+_68047418 1.51 ENST00000586373.1
ENST00000588782.1
long intergenic non-protein coding RNA 1028
chr12_-_49463620 1.17 ENST00000550675.1
Ras homolog enriched in brain like 1
chr19_-_13900972 0.99 ENST00000397557.1
Uncharacterized protein
chr12_-_111142729 0.98 ENST00000546713.1
hydrogen voltage-gated channel 1
chr3_+_167582561 0.90 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
chr11_+_115498761 0.87 ENST00000424313.2
AP000997.1
chr19_+_58193388 0.83 ENST00000596085.1
ENST00000594684.1
zinc finger protein 551
Uncharacterized protein
chr16_-_21863541 0.83 ENST00000543654.1
nuclear pore complex interacting protein family, member B4
chr5_+_127039075 0.83 ENST00000514853.2
CTC-228N24.1
chr3_+_169629354 0.76 ENST00000428432.2
ENST00000335556.3
sterile alpha motif domain containing 7
chr17_-_15469590 0.74 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr14_-_75735986 0.74 ENST00000553510.1
Uncharacterized protein
chr19_-_6057282 0.70 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr18_-_74839891 0.68 ENST00000581878.1
myelin basic protein
chr12_+_110011571 0.66 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr10_-_69991865 0.62 ENST00000373673.3
atonal homolog 7 (Drosophila)
chr17_-_28661065 0.61 ENST00000328886.4
ENST00000538566.2
transmembrane and immunoglobulin domain containing 1
chr1_+_40810516 0.60 ENST00000435168.2
small ArfGAP2
chr8_-_65730127 0.59 ENST00000522106.1
RP11-1D12.2
chr8_-_91618285 0.58 ENST00000517505.1
long intergenic non-protein coding RNA 1030
chr6_+_26199737 0.57 ENST00000359985.1
histone cluster 1, H2bf
chr18_+_22040593 0.57 ENST00000256906.4
histamine receptor H4
chr6_-_26124138 0.56 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr10_-_99052382 0.56 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr6_+_29624758 0.55 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
myelin oligodendrocyte glycoprotein
chr3_-_165555200 0.54 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr19_+_49199209 0.54 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr18_-_44500101 0.54 ENST00000589917.1
ENST00000587810.1
protein inhibitor of activated STAT, 2
chr13_+_110958124 0.54 ENST00000400163.2
collagen, type IV, alpha 2
chr7_+_138915102 0.54 ENST00000486663.1
ubinuclein 2
chr14_-_92247032 0.52 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr8_+_82066514 0.52 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
chr11_+_327171 0.51 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr4_-_110736505 0.51 ENST00000609440.1
RP11-602N24.3
chr21_+_17909594 0.49 ENST00000441820.1
ENST00000602280.1
long intergenic non-protein coding RNA 478
chr4_-_90759440 0.49 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_58459039 0.48 ENST00000282308.3
ENST00000598928.1
zinc finger protein 256
chr16_+_14802801 0.47 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr4_-_90757364 0.47 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_147052 0.46 ENST00000594563.1
Uncharacterized protein
chr4_+_71019903 0.46 ENST00000344526.5
chromosome 4 open reading frame 40
chr3_+_57094469 0.45 ENST00000334325.1
spermatogenesis associated 12
chr19_-_43709772 0.45 ENST00000596907.1
ENST00000451895.1
pregnancy specific beta-1-glycoprotein 4
chr5_-_94417339 0.45 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr1_+_151693984 0.44 ENST00000479191.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr1_+_39734131 0.44 ENST00000530262.1
microtubule-actin crosslinking factor 1
chr6_+_144665237 0.44 ENST00000421035.2
utrophin
chr18_+_72166564 0.43 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr10_-_61900762 0.43 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr12_+_107078474 0.42 ENST00000552866.1
ENST00000229387.5
regulatory factor X, 4 (influences HLA class II expression)
chr5_-_94417314 0.42 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr12_-_123450986 0.42 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr2_+_108905325 0.42 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
sulfotransferase family, cytosolic, 1C, member 2
chr11_-_111649015 0.41 ENST00000529841.1
RP11-108O10.2
chr19_+_41281416 0.41 ENST00000597140.1
melanoma inhibitory activity
chr9_+_105757590 0.40 ENST00000374798.3
ENST00000487798.1
cylicin, basic protein of sperm head cytoskeleton 2
chr4_-_90756769 0.40 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr9_+_132099158 0.40 ENST00000444125.1
RP11-65J3.1
chr2_+_219472637 0.40 ENST00000417849.1
phospholipase C, delta 4
chr21_-_43735628 0.40 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr2_+_242312264 0.39 ENST00000445489.1
FERM, RhoGEF and pleckstrin domain protein 2
chr11_+_7618413 0.39 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_94417186 0.38 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr12_+_128399965 0.38 ENST00000540882.1
ENST00000542089.1
long intergenic non-protein coding RNA 507
chr11_-_111649074 0.37 ENST00000534218.1
RP11-108O10.2
chr16_-_56223480 0.37 ENST00000565155.1
RP11-461O7.1
chr19_+_58193337 0.37 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
zinc finger protein 551
chr4_+_6717842 0.36 ENST00000320776.3
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr17_+_32597232 0.35 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
chemokine (C-C motif) ligand 7
chr5_+_138611798 0.35 ENST00000502394.1
matrin 3
chr15_+_69857515 0.35 ENST00000559477.1
RP11-279F6.1
chr1_+_62439037 0.35 ENST00000545929.1
InaD-like (Drosophila)
chr7_+_138943265 0.35 ENST00000483726.1
ubinuclein 2
chr8_-_133772870 0.35 ENST00000522334.1
ENST00000519016.1
transmembrane protein 71
chr10_-_99030395 0.35 ENST00000355366.5
ENST00000371027.1
Rho GTPase activating protein 19
chr8_-_42396185 0.34 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr9_-_95055923 0.34 ENST00000430417.1
isoleucyl-tRNA synthetase
chr3_+_195413160 0.34 ENST00000599448.1
long intergenic non-protein coding RNA 969
chr7_-_77325545 0.34 ENST00000447009.1
ENST00000416650.1
ENST00000440088.1
ENST00000430801.1
ENST00000398043.2
RSBN1L antisense RNA 1
chr5_-_74162739 0.34 ENST00000513277.1
family with sequence similarity 169, member A
chr4_+_22999152 0.34 ENST00000511453.1
RP11-412P11.1
chr12_+_100867486 0.34 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr6_+_31105426 0.34 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr4_+_25915896 0.33 ENST00000514384.1
small integral membrane protein 20
chr11_-_125773085 0.33 ENST00000227474.3
ENST00000534158.1
ENST00000529801.1
pseudouridylate synthase 3
chr17_-_76732928 0.33 ENST00000589768.1
cytohesin 1
chr16_+_14844670 0.33 ENST00000553201.1
nuclear pore complex interacting protein family, member A2
chr8_-_13134045 0.33 ENST00000512044.2
deleted in liver cancer 1
chr2_+_47799601 0.32 ENST00000601243.1
CDNA: FLJ23120 fis, clone LNG07989; HCG1987724; Uncharacterized protein
chr4_+_56815102 0.32 ENST00000257287.4
centrosomal protein 135kDa
chr3_-_105588231 0.32 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr9_+_123884038 0.32 ENST00000373847.1
centriolin
chr18_+_47087055 0.32 ENST00000577628.1
lipase, endothelial
chr9_+_5890802 0.32 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
melan-A
chr11_+_5710919 0.31 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr19_-_16008880 0.31 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr10_+_48189612 0.31 ENST00000453919.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr14_+_20187174 0.31 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chr9_-_85882145 0.31 ENST00000328788.1
FERM domain containing 3
chr11_-_8857248 0.31 ENST00000534248.1
ENST00000530959.1
ENST00000531578.1
ENST00000533225.1
suppression of tumorigenicity 5
chr6_+_27791862 0.31 ENST00000355057.1
histone cluster 1, H4j
chr12_+_76653611 0.31 ENST00000550380.1
RP11-54A9.1
chr1_+_117963209 0.31 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr22_+_39795746 0.31 ENST00000216160.6
ENST00000331454.3
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr12_+_57810198 0.31 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr6_-_53481847 0.30 ENST00000503985.1
RP1-27K12.2
chr6_+_134758827 0.30 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr16_-_21663950 0.30 ENST00000268389.4
immunoglobulin superfamily, member 6
chr10_-_95241951 0.30 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr6_+_168196210 0.30 ENST00000597278.1
Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793
chr12_+_76653682 0.29 ENST00000553247.1
RP11-54A9.1
chr5_-_135290705 0.29 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr2_+_211342400 0.29 ENST00000417946.1
ENST00000518043.1
ENST00000523702.1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_-_160492994 0.29 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAM family member 6
chr19_-_44809121 0.29 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
zinc finger protein 235
chr1_-_214638146 0.29 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr4_-_177116772 0.29 ENST00000280191.2
spermatogenesis associated 4
chrX_+_36053908 0.29 ENST00000378660.2
calponin homology domain containing 2
chr1_+_171217622 0.29 ENST00000433267.1
ENST00000367750.3
flavin containing monooxygenase 1
chrX_+_41583408 0.29 ENST00000302548.4
G protein-coupled receptor 82
chr6_-_170151603 0.29 ENST00000366774.3
t-complex-associated-testis-expressed 3
chr1_+_81106951 0.29 ENST00000443565.1
RP5-887A10.1
chr4_+_25915822 0.29 ENST00000506197.2
small integral membrane protein 20
chr12_+_21525818 0.28 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chr7_+_107224364 0.28 ENST00000491150.1
B-cell receptor-associated protein 29
chr18_-_46895066 0.28 ENST00000583225.1
ENST00000584983.1
ENST00000583280.1
ENST00000581738.1
dymeclin
chr6_-_53481768 0.28 ENST00000505197.1
ENST00000505995.1
ENST00000502390.1
ENST00000506206.1
ENST00000510846.1
glutamate-cysteine ligase, catalytic subunit
RP1-27K12.2
chr14_+_64565442 0.28 ENST00000553308.1
spectrin repeat containing, nuclear envelope 2
chr17_-_42992856 0.27 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr19_+_54466179 0.27 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr6_-_27858570 0.27 ENST00000359303.2
histone cluster 1, H3j
chr11_+_63304273 0.27 ENST00000439013.2
ENST00000255688.3
retinoic acid receptor responder (tazarotene induced) 3
chr6_+_147830362 0.27 ENST00000566741.1
sterile alpha motif domain containing 5
chr10_-_22292675 0.27 ENST00000376946.1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr6_-_105307417 0.27 ENST00000524020.1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr1_-_89641680 0.27 ENST00000294671.2
guanylate binding protein 7
chr18_+_33552667 0.26 ENST00000333234.5
chromosome 18 open reading frame 21
chr6_+_131958436 0.26 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_+_10222189 0.26 ENST00000321826.4
purinergic receptor P2Y, G-protein coupled, 11
chr5_+_140227357 0.26 ENST00000378122.3
protocadherin alpha 9
chr1_+_15943995 0.26 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr15_-_78913628 0.26 ENST00000348639.3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr1_+_225600404 0.25 ENST00000366845.2
AC092811.1
chr14_+_64680854 0.25 ENST00000458046.2
spectrin repeat containing, nuclear envelope 2
chr7_-_24957699 0.25 ENST00000441059.1
ENST00000415162.1
oxysterol binding protein-like 3
chr2_-_225811747 0.25 ENST00000409592.3
dedicator of cytokinesis 10
chr14_+_50291993 0.25 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr17_-_12920907 0.25 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
elaC ribonuclease Z 2
chr17_-_34195862 0.24 ENST00000592980.1
ENST00000587626.1
chromosome 17 open reading frame 66
chr16_+_70258261 0.24 ENST00000594734.1
FKSG63
chr15_-_30261066 0.24 ENST00000558447.1
tight junction protein 1
chr12_-_15374343 0.24 ENST00000256953.2
ENST00000546331.1
RAS-like, estrogen-regulated, growth inhibitor
chr12_+_128399917 0.24 ENST00000544645.1
long intergenic non-protein coding RNA 507
chr5_-_142077569 0.24 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
fibroblast growth factor 1 (acidic)
chr11_-_71823715 0.24 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr13_-_30160925 0.24 ENST00000450494.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_12806141 0.24 ENST00000288048.5
chromosome 1 open reading frame 158
chr3_-_124839648 0.24 ENST00000430155.2
solute carrier family 12, member 8
chr1_-_150978953 0.24 ENST00000493834.2
family with sequence similarity 63, member A
chr2_+_234826016 0.24 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr11_-_64684672 0.24 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr19_-_48389651 0.23 ENST00000222002.3
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr16_-_28634874 0.23 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_+_66521936 0.23 ENST00000592800.1
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr18_+_61575200 0.23 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr8_-_93978309 0.23 ENST00000517858.1
ENST00000378861.5
triple QxxK/R motif containing
chr9_+_104296163 0.23 ENST00000374819.2
ENST00000479306.1
ring finger protein 20, E3 ubiquitin protein ligase
chr9_-_100684769 0.23 ENST00000455506.1
ENST00000375117.4
chromosome 9 open reading frame 156
chr16_+_14805546 0.23 ENST00000552140.1
nuclear pore complex interacting protein family, member A3
chr12_+_26164645 0.23 ENST00000542004.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_+_25652501 0.23 ENST00000334979.6
secretagogin, EF-hand calcium binding protein
chr2_+_27851106 0.23 ENST00000515877.1
GPN-loop GTPase 1
chr12_+_14572070 0.22 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr14_+_74417192 0.22 ENST00000554320.1
coenzyme Q6 monooxygenase
chr5_-_42812143 0.22 ENST00000514985.1
selenoprotein P, plasma, 1
chr4_-_10686475 0.22 ENST00000226951.6
cytokine-dependent hematopoietic cell linker
chr19_-_58204128 0.22 ENST00000597520.1
Uncharacterized protein
chr16_+_33204156 0.22 ENST00000398667.4
TP53 target 3C
chr3_-_151176497 0.22 ENST00000282466.3
immunoglobulin superfamily, member 10
chr7_-_112430427 0.22 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
transmembrane protein 168
chr7_-_130066571 0.22 ENST00000492389.1
centrosomal protein 41kDa
chr19_-_6379069 0.22 ENST00000597721.1
persephin
chr7_+_141695671 0.21 ENST00000497673.1
ENST00000475668.2
maltase-glucoamylase (alpha-glucosidase)
chr14_-_73997901 0.21 ENST00000557603.1
ENST00000556455.1
HEAT repeat containing 4
chr4_+_165878100 0.21 ENST00000513876.2
family with sequence similarity 218, member A
chr6_+_30844192 0.21 ENST00000502955.1
ENST00000505066.1
discoidin domain receptor tyrosine kinase 1
chr3_+_16216137 0.21 ENST00000339732.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr2_-_136873735 0.21 ENST00000409817.1
chemokine (C-X-C motif) receptor 4
chr9_+_27109133 0.21 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr11_+_5711010 0.21 ENST00000454828.1
tripartite motif containing 22
chr15_-_99791413 0.21 ENST00000394129.2
ENST00000558663.1
ENST00000394135.3
ENST00000561365.1
ENST00000560279.1
tetratricopeptide repeat domain 23
chr7_+_139529085 0.20 ENST00000539806.1
thromboxane A synthase 1 (platelet)
chr8_+_109455830 0.20 ENST00000524143.1
ER membrane protein complex subunit 2
chr1_-_21377447 0.20 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_112013071 0.20 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr3_-_69062790 0.20 ENST00000540955.1
ENST00000456376.1
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr19_+_42212501 0.20 ENST00000398599.4
carcinoembryonic antigen-related cell adhesion molecule 5
chr9_+_27109392 0.20 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr3_+_159557637 0.20 ENST00000445224.2
schwannomin interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.7 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.4 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.7 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0003095 pressure natriuresis(GO:0003095) negative regulation of icosanoid secretion(GO:0032304)
0.1 0.3 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.5 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 0.3 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:1900673 phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.3 GO:0035766 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.3 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.6 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.4 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0070316 regulation of G0 to G1 transition(GO:0070316)
0.0 0.6 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.3 GO:0001501 skeletal system development(GO:0001501)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) regulation of protein autoubiquitination(GO:1902498)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0014870 response to muscle inactivity(GO:0014870)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0034982 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.0 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:1904430 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.1 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.5 GO:0036128 CatSper complex(GO:0036128)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.1 GO:0005712 chiasma(GO:0005712)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.5 GO:0033265 choline binding(GO:0033265)
0.2 1.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.4 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.4 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.4 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.5 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0016160 amylase activity(GO:0016160)
0.0 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) mediator complex binding(GO:0036033)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0099589 serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004325 ferrochelatase activity(GO:0004325)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates