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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXA2_HOXB1

Z-value: 0.26

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Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
ENSG00000105996.5 homeobox A2
ENSG00000120094.6 homeobox B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB1hg19_v2_chr17_-_46608272_466083850.236.6e-01Click!
HOXA2hg19_v2_chr7_-_27142290_271424300.226.8e-01Click!

Activity profile of HOXA2_HOXB1 motif

Sorted Z-values of HOXA2_HOXB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_162864575 0.27 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chr17_+_7758374 0.20 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chrX_-_45629661 0.16 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr16_+_85936295 0.14 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
interferon regulatory factor 8
chr16_-_67427389 0.12 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr12_+_21679220 0.12 ENST00000256969.2
chromosome 12 open reading frame 39
chr1_-_108507631 0.12 ENST00000527011.1
ENST00000370056.4
vav 3 guanine nucleotide exchange factor
chr2_-_154335300 0.12 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_+_77596014 0.09 ENST00000523885.1
zinc finger homeobox 4
chr1_-_217804377 0.09 ENST00000366935.3
ENST00000366934.3
G patch domain containing 2
chr2_+_176995011 0.08 ENST00000548663.1
ENST00000450510.2
homeobox D8
chrX_+_95939638 0.08 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr11_+_133902547 0.08 ENST00000529070.1
RP11-713P17.3
chr7_-_27170352 0.08 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr5_+_98109322 0.08 ENST00000513185.1
repulsive guidance molecule family member b
chrX_+_95939711 0.08 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr16_-_49890016 0.07 ENST00000563137.2
zinc finger protein 423
chr1_-_65533390 0.07 ENST00000448344.1
RP4-535B20.1
chr17_-_46623441 0.07 ENST00000330070.4
homeobox B2
chr8_-_79717750 0.07 ENST00000263851.4
ENST00000379113.2
interleukin 7
chr7_-_14029283 0.07 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr2_+_121493717 0.06 ENST00000418323.1
GLI family zinc finger 2
chr9_+_40028620 0.06 ENST00000426179.1
AL353791.1
chr10_-_46342921 0.06 ENST00000448048.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
chr3_+_159481988 0.06 ENST00000472451.1
IQCJ-SCHIP1 readthrough
chr10_+_89264625 0.06 ENST00000371996.4
ENST00000371994.4
multiple inositol-polyphosphate phosphatase 1
chr3_-_98619999 0.05 ENST00000449482.1
discoidin, CUB and LCCL domain containing 2
chr12_+_57390745 0.05 ENST00000600202.1
HBcAg-binding protein; Uncharacterized protein
chr11_-_2162162 0.05 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr7_+_79765071 0.05 ENST00000457358.2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr15_-_93616340 0.05 ENST00000557420.1
ENST00000542321.2
repulsive guidance molecule family member a
chr7_-_14029515 0.05 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr9_-_101471479 0.04 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_-_45735138 0.04 ENST00000252482.3
exocyst complex component 3-like 2
chr11_-_126174186 0.04 ENST00000524964.1
Uncharacterized protein
chr12_-_28125638 0.04 ENST00000545234.1
parathyroid hormone-like hormone
chr15_+_75335604 0.04 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr8_-_67874805 0.04 ENST00000563496.1
transcription factor 24
chrX_+_99899180 0.04 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr3_+_112929850 0.04 ENST00000464546.1
BOC cell adhesion associated, oncogene regulated
chr12_+_57482877 0.04 ENST00000342556.6
ENST00000357680.4
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_+_43239191 0.04 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chr7_-_120497178 0.03 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr17_-_37353950 0.03 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
calcium channel, voltage-dependent, beta 1 subunit
chr1_-_109584716 0.03 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WD repeat domain 47
chr1_+_52082751 0.03 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
oxysterol binding protein-like 9
chr1_+_67390578 0.03 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
mesoderm induction early response 1, transcriptional regulator
chr6_+_32006159 0.03 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr18_+_18943554 0.03 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr10_-_65028817 0.03 ENST00000542921.1
jumonji domain containing 1C
chr8_+_22250334 0.03 ENST00000520832.1
solute carrier family 39 (zinc transporter), member 14
chr1_-_43833628 0.03 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr15_-_74501360 0.03 ENST00000323940.5
stimulated by retinoic acid 6
chr5_+_167181917 0.03 ENST00000519204.1
teneurin transmembrane protein 2
chr8_+_143530791 0.03 ENST00000517894.1
brain-specific angiogenesis inhibitor 1
chr6_+_73331520 0.03 ENST00000342056.2
ENST00000355194.4
potassium voltage-gated channel, KQT-like subfamily, member 5
chr16_+_66429358 0.02 ENST00000539168.1
cadherin 5, type 2 (vascular endothelium)
chr19_+_44645731 0.02 ENST00000426739.2
zinc finger protein 234
chr2_-_242089677 0.02 ENST00000405260.1
PAS domain containing serine/threonine kinase
chr6_-_64029879 0.02 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
lengsin, lens protein with glutamine synthetase domain
chr12_-_28124903 0.02 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr10_-_98945515 0.02 ENST00000371070.4
slit homolog 1 (Drosophila)
chr17_+_43239231 0.02 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr10_-_65028938 0.02 ENST00000402544.1
jumonji domain containing 1C
chr10_+_24755416 0.02 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr10_-_79397547 0.02 ENST00000481070.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_159065741 0.02 ENST00000367085.3
ENST00000367089.3
dynein, light chain, Tctex-type 1
chr19_+_52074502 0.02 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
zinc finger protein 175
chr13_+_36050881 0.02 ENST00000537702.1
neurobeachin
chr19_+_37997812 0.02 ENST00000542455.1
ENST00000587143.1
zinc finger protein 793
chr2_-_145277882 0.02 ENST00000465070.1
ENST00000444559.1
zinc finger E-box binding homeobox 2
chr3_+_189507432 0.02 ENST00000354600.5
tumor protein p63
chr9_-_26947453 0.02 ENST00000397292.3
phospholipase A2-activating protein
chr11_-_111782484 0.02 ENST00000533971.1
crystallin, alpha B
chr2_+_12857015 0.02 ENST00000155926.4
tribbles pseudokinase 2
chr2_+_114647504 0.02 ENST00000263238.2
ARP3 actin-related protein 3 homolog (yeast)
chr7_-_78400598 0.02 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_-_98945264 0.02 ENST00000314867.5
slit homolog 1 (Drosophila)
chr16_-_11617444 0.02 ENST00000598234.1
Protein LOC388210
chr5_+_145826867 0.02 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr7_-_100881109 0.02 ENST00000308344.5
claudin 15
chr18_-_53070913 0.01 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr2_-_200323414 0.01 ENST00000443023.1
SATB homeobox 2
chr9_+_113431029 0.01 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
muscle, skeletal, receptor tyrosine kinase
chr12_-_57472522 0.01 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr7_-_27142290 0.01 ENST00000222718.5
homeobox A2
chr2_+_242089833 0.01 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
protein phosphatase 1, regulatory subunit 7
chr3_+_189507523 0.01 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr11_-_93583697 0.01 ENST00000409977.1
V-set and transmembrane domain containing 5
chr2_+_26624775 0.01 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr6_-_113754604 0.01 ENST00000421737.1
RP1-124C6.1
chr1_+_178062855 0.01 ENST00000448150.3
RAS protein activator like 2
chr2_-_145278475 0.01 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr2_-_44588694 0.01 ENST00000409957.1
prolyl endopeptidase-like
chr19_+_44645700 0.01 ENST00000592437.1
zinc finger protein 234
chr7_+_1272522 0.01 ENST00000316333.8
UNC homeobox
chr14_-_24733444 0.01 ENST00000560478.1
ENST00000560443.1
transglutaminase 1
chr10_-_79397316 0.01 ENST00000372421.5
ENST00000457953.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_-_49944806 0.01 ENST00000221485.3
solute carrier family 17 (vesicular glutamate transporter), member 7
chr15_+_81591757 0.01 ENST00000558332.1
interleukin 16
chr22_-_39151463 0.01 ENST00000405510.1
ENST00000433561.1
Sad1 and UNC84 domain containing 2
chr11_-_111782696 0.01 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr12_+_56414795 0.01 ENST00000431367.2
IKAROS family zinc finger 4 (Eos)
chr2_-_44588679 0.01 ENST00000409411.1
prolyl endopeptidase-like
chr3_+_239652 0.01 ENST00000435603.1
cell adhesion molecule L1-like
chr3_-_72150076 0.01 ENST00000488545.1
ENST00000608654.1
long intergenic non-protein coding RNA 877
chr9_-_127269661 0.01 ENST00000373588.4
nuclear receptor subfamily 5, group A, member 1
chrX_-_110655306 0.01 ENST00000371993.2
doublecortin
chr11_-_126870683 0.01 ENST00000525704.2
kin of IRRE like 3 (Drosophila)
chr9_-_36276966 0.01 ENST00000543356.2
ENST00000396594.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr12_+_56414851 0.01 ENST00000547167.1
IKAROS family zinc finger 4 (Eos)
chr8_-_79717163 0.01 ENST00000520269.1
interleukin 7
chr10_-_79397479 0.00 ENST00000404771.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_109584608 0.00 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr2_+_54684327 0.00 ENST00000389980.3
spectrin, beta, non-erythrocytic 1
chr12_+_10658489 0.00 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr7_-_78400364 0.00 ENST00000535697.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_-_79397202 0.00 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_+_39975455 0.00 ENST00000455106.1
FK506 binding protein 10, 65 kDa
chr2_-_197226875 0.00 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr15_-_93616892 0.00 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
repulsive guidance molecule family member a
chr9_+_113431059 0.00 ENST00000416899.2
muscle, skeletal, receptor tyrosine kinase
chr10_-_98945677 0.00 ENST00000266058.4
ENST00000371041.3
slit homolog 1 (Drosophila)
chr5_-_179045199 0.00 ENST00000523921.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr7_+_86273218 0.00 ENST00000361669.2
glutamate receptor, metabotropic 3
chr17_-_46608272 0.00 ENST00000577092.1
ENST00000239174.6
homeobox B1
chr1_-_67390474 0.00 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WD repeat domain 78
chr13_+_97928395 0.00 ENST00000445661.2
muscleblind-like splicing regulator 2
chr12_-_118490217 0.00 ENST00000542304.1
WD repeat and SOCS box containing 2
chr2_+_12857043 0.00 ENST00000381465.2
tribbles pseudokinase 2
chrX_-_110655391 0.00 ENST00000356915.2
ENST00000356220.3
doublecortin
chr17_+_39975544 0.00 ENST00000544340.1
FK506 binding protein 10, 65 kDa
chr12_+_7282795 0.00 ENST00000266546.6
calsyntenin 3
chr4_+_129732467 0.00 ENST00000413543.2
jade family PHD finger 1
chrX_-_10645773 0.00 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)