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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB6_PRRX2

Z-value: 0.72

Motif logo

Transcription factors associated with HOXB6_PRRX2

Gene Symbol Gene ID Gene Info
ENSG00000108511.8 homeobox B6
ENSG00000167157.9 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB6hg19_v2_chr17_-_46682321_46682362-0.661.6e-01Click!
PRRX2hg19_v2_chr9_+_132427883_132427951-0.493.3e-01Click!

Activity profile of HOXB6_PRRX2 motif

Sorted Z-values of HOXB6_PRRX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_105404899 1.06 ENST00000345080.4
lin-28 homolog B (C. elegans)
chr17_-_56082455 1.01 ENST00000578794.1
Uncharacterized protein
chrM_+_9207 0.80 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr20_+_5987890 0.79 ENST00000378868.4
cardiolipin synthase 1
chr7_-_83824449 0.76 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_142264664 0.75 ENST00000518520.1
Uncharacterized protein
chrM_+_10758 0.75 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr12_+_28410128 0.64 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chrM_+_10464 0.62 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chrX_-_45629661 0.61 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr5_-_76935513 0.57 ENST00000306422.3
orthopedia homeobox
chr1_+_61869748 0.57 ENST00000357977.5
nuclear factor I/A
chr9_-_3469181 0.57 ENST00000366116.2
Uncharacterized protein
chr2_+_173955327 0.54 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr8_-_95449155 0.54 ENST00000481490.2
fibrinogen silencer binding protein
chr1_+_205682497 0.53 ENST00000598338.1
AC119673.1
chr16_+_53133070 0.51 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chrM_+_8366 0.51 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr4_-_36245561 0.47 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_95616933 0.46 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr1_+_167298281 0.46 ENST00000367862.5
POU class 2 homeobox 1
chrM_+_8527 0.45 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr13_-_86373536 0.45 ENST00000400286.2
SLIT and NTRK-like family, member 6
chrX_-_20237059 0.45 ENST00000457145.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_-_92413727 0.44 ENST00000267620.10
fibulin 5
chr12_+_86268065 0.44 ENST00000551529.1
ENST00000256010.6
neurotensin
chr11_-_126810521 0.44 ENST00000530572.1
RP11-688I9.4
chr4_+_95174445 0.43 ENST00000509418.1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_+_39846114 0.43 ENST00000586699.1
eukaryotic translation initiation factor 1
chr7_-_14026123 0.41 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chrX_+_123097014 0.39 ENST00000394478.1
stromal antigen 2
chrX_-_119693745 0.38 ENST00000371323.2
cullin 4B
chr11_+_34642656 0.37 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr7_-_81635106 0.37 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr2_+_191792376 0.37 ENST00000409428.1
ENST00000409215.1
glutaminase
chr3_+_136649311 0.37 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr2_+_182850551 0.36 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chrM_+_5824 0.36 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr9_-_37384431 0.34 ENST00000452923.1
RP11-397D12.4
chr14_-_92413353 0.34 ENST00000556154.1
fibulin 5
chr5_-_41510725 0.33 ENST00000328457.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_-_111291587 0.33 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr14_-_75083313 0.32 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr7_-_27205136 0.32 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr14_+_61449197 0.32 ENST00000533744.2
solute carrier family 38, member 6
chr4_+_90033968 0.32 ENST00000317005.2
tigger transposable element derived 2
chr5_-_87516448 0.31 ENST00000511218.1
transmembrane protein 161B
chr17_-_39093672 0.31 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr16_-_51185172 0.31 ENST00000251020.4
spalt-like transcription factor 1
chr9_-_123812542 0.31 ENST00000223642.1
complement component 5
chr3_-_78719376 0.30 ENST00000495961.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_-_10115007 0.30 ENST00000485268.1
orofacial cleft 1 candidate 1
chr1_+_84629976 0.30 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chrM_+_10053 0.28 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chrM_+_14741 0.28 ENST00000361789.2
mitochondrially encoded cytochrome b
chr14_+_32476072 0.28 ENST00000556949.1
Uncharacterized protein
chr21_+_17443521 0.28 ENST00000456342.1
long intergenic non-protein coding RNA 478
chr8_-_90993869 0.28 ENST00000517772.1
nibrin
chr12_+_2912363 0.28 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr6_+_144980954 0.28 ENST00000367525.3
utrophin
chr3_-_4793274 0.28 ENST00000414938.1
eosinophil granule ontogeny transcript (non-protein coding)
chr3_+_88188254 0.28 ENST00000309495.5
zinc finger protein 654
chr15_+_57511609 0.28 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr4_-_153274078 0.27 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr15_-_54025300 0.27 ENST00000559418.1
WD repeat domain 72
chr8_+_42873548 0.27 ENST00000533338.1
ENST00000534420.1
hook microtubule-tethering protein 3
Uncharacterized protein
chr7_+_142374104 0.27 ENST00000604952.1
MT-RNR2-like 6
chr6_-_76203345 0.27 ENST00000393004.2
filamin A interacting protein 1
chr12_-_94673956 0.27 ENST00000551941.1
Uncharacterized protein
chr12_-_102591604 0.27 ENST00000329406.4
pro-melanin-concentrating hormone
chr5_-_58295712 0.27 ENST00000317118.8
phosphodiesterase 4D, cAMP-specific
chr17_-_38956205 0.26 ENST00000306658.7
keratin 28
chr2_-_27938593 0.26 ENST00000379677.2
Uncharacterized protein
chr7_-_83824169 0.26 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_186265399 0.26 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr13_+_36050881 0.26 ENST00000537702.1
neurobeachin
chr17_-_61045902 0.26 ENST00000581596.1
RP11-180P8.3
chr2_+_210444748 0.26 ENST00000392194.1
microtubule-associated protein 2
chr12_+_20963647 0.25 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr6_-_76203454 0.25 ENST00000237172.7
filamin A interacting protein 1
chr7_-_27170352 0.25 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr8_-_122653630 0.25 ENST00000303924.4
hyaluronan synthase 2
chr13_+_78315348 0.25 ENST00000441784.1
SLAIN motif family, member 1
chr12_-_92536433 0.25 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr18_-_52989525 0.25 ENST00000457482.3
transcription factor 4
chr15_+_96897466 0.24 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
chr15_+_49715449 0.24 ENST00000560979.1
fibroblast growth factor 7
chr2_+_162101247 0.24 ENST00000439050.1
ENST00000436506.1
AC009299.3
chr16_+_53242350 0.24 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr4_-_105416039 0.24 ENST00000394767.2
CXXC finger protein 4
chr1_-_241799232 0.24 ENST00000366553.1
choroideremia-like (Rab escort protein 2)
chr17_-_46692457 0.24 ENST00000468443.1
homeobox B8
chrM_+_7586 0.24 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr9_+_22646189 0.24 ENST00000436786.1
RP11-399D6.2
chr16_-_67517716 0.23 ENST00000290953.2
agouti related protein homolog (mouse)
chr16_+_53241854 0.23 ENST00000565803.1
chromodomain helicase DNA binding protein 9
chr3_-_196910721 0.23 ENST00000443183.1
discs, large homolog 1 (Drosophila)
chr3_+_69928256 0.23 ENST00000394355.2
microphthalmia-associated transcription factor
chr11_-_13461790 0.23 ENST00000530907.1
BTB (POZ) domain containing 10
chr4_+_108815402 0.23 ENST00000503385.1
sphingomyelin synthase 2
chr2_-_200715573 0.23 ENST00000420922.2
formiminotransferase cyclodeaminase N-terminal like
chr1_+_199996733 0.23 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr15_+_80351977 0.23 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr13_+_78315295 0.22 ENST00000351546.3
SLAIN motif family, member 1
chr3_+_141106458 0.22 ENST00000509883.1
zinc finger and BTB domain containing 38
chr13_-_31191642 0.22 ENST00000405805.1
high mobility group box 1
chr11_+_28724129 0.22 ENST00000513853.1
RP11-115J23.1
chr6_+_130339710 0.22 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr4_-_99578776 0.22 ENST00000515287.1
tetraspanin 5
chr6_+_111195973 0.22 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr7_-_92777606 0.22 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr2_+_172309634 0.21 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr10_-_104866395 0.21 ENST00000458345.1
5'-nucleotidase, cytosolic II
chr11_-_85430204 0.21 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chrX_-_20236970 0.21 ENST00000379548.4
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_-_155533787 0.21 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr3_-_196910477 0.21 ENST00000447466.1
discs, large homolog 1 (Drosophila)
chr5_-_58882219 0.21 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chrX_-_15683147 0.21 ENST00000380342.3
transmembrane protein 27
chr12_-_110937351 0.21 ENST00000552130.2
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_-_59783882 0.21 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr6_+_136172820 0.21 ENST00000308191.6
phosphodiesterase 7B
chr5_+_56471592 0.21 ENST00000511209.1
GC-rich promoter binding protein 1
chr5_-_41510656 0.21 ENST00000377801.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr10_+_94594351 0.20 ENST00000371552.4
exocyst complex component 6
chr12_+_20963632 0.20 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr21_-_35899113 0.20 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr14_-_35099377 0.20 ENST00000362031.4
sorting nexin 6
chr12_-_12674032 0.20 ENST00000298573.4
dual specificity phosphatase 16
chr2_+_182850743 0.20 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_+_84630053 0.20 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_20621834 0.20 ENST00000429426.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_+_35222629 0.20 ENST00000526553.1
CD44 molecule (Indian blood group)
chr4_+_155484155 0.20 ENST00000509493.1
fibrinogen beta chain
chr10_-_36812323 0.20 ENST00000543053.1
nicotinamide phosphoribosyltransferase-like
chr6_-_108278456 0.20 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr2_+_161993465 0.20 ENST00000457476.1
TRAF family member-associated NFKB activator
chr12_-_16760021 0.20 ENST00000540445.1
LIM domain only 3 (rhombotin-like 2)
chr17_-_38821373 0.20 ENST00000394052.3
keratin 222
chr4_+_129730947 0.20 ENST00000452328.2
ENST00000504089.1
jade family PHD finger 1
chr8_-_99837856 0.20 ENST00000518165.1
ENST00000419617.2
serine/threonine kinase 3
chr3_+_152017360 0.19 ENST00000485910.1
ENST00000463374.1
muscleblind-like splicing regulator 1
chr10_-_21186144 0.19 ENST00000377119.1
nebulette
chr4_+_155484103 0.19 ENST00000302068.4
fibrinogen beta chain
chr11_+_107879459 0.19 ENST00000393094.2
cullin 5
chr5_-_111092930 0.19 ENST00000257435.7
neuronal regeneration related protein
chr11_+_17316870 0.19 ENST00000458064.2
nucleobindin 2
chr2_+_29001711 0.19 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr4_+_26324474 0.19 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr1_+_199996702 0.19 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr2_-_136678123 0.19 ENST00000422708.1
aspartyl-tRNA synthetase
chr8_-_42358742 0.19 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr10_-_77161004 0.19 ENST00000418818.2
RP11-399K21.11
chr7_-_33080506 0.19 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
5'-nucleotidase, cytosolic IIIA
chr13_+_31191920 0.19 ENST00000255304.4
ubiquitin specific peptidase like 1
chr12_+_79258444 0.19 ENST00000261205.4
synaptotagmin I
chr9_-_16253112 0.19 ENST00000380683.1
chromosome 9 open reading frame 92
chr8_-_25281747 0.19 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr6_-_32157947 0.18 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr8_-_128231299 0.18 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr4_+_15683404 0.18 ENST00000422728.2
family with sequence similarity 200, member B
chr8_-_108510224 0.18 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr12_-_90049878 0.18 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chr6_+_64346386 0.18 ENST00000509330.1
PHD finger protein 3
chr16_-_3350614 0.18 ENST00000268674.2
tigger transposable element derived 7
chr4_-_176733897 0.18 ENST00000393658.2
glycoprotein M6A
chr6_+_155537771 0.18 ENST00000275246.7
T-cell lymphoma invasion and metastasis 2
chr19_-_7698599 0.18 ENST00000311069.5
Purkinje cell protein 2
chr11_-_62437486 0.18 ENST00000528115.1
chromosome 11 open reading frame 48
chr6_-_85474219 0.18 ENST00000369663.5
T-box 18
chr10_+_126630692 0.18 ENST00000359653.4
zinc finger, RAN-binding domain containing 1
chr5_-_1882858 0.17 ENST00000511126.1
ENST00000231357.2
iroquois homeobox 4
chr20_-_44455976 0.17 ENST00000372555.3
troponin C type 2 (fast)
chr7_+_135611542 0.17 ENST00000416501.1
AC015987.2
chr17_+_22022437 0.17 ENST00000540040.1
MT-RNR2-like 1
chr9_+_135457530 0.17 ENST00000263610.2
BarH-like homeobox 1
chr20_-_50418947 0.17 ENST00000371539.3
spalt-like transcription factor 4
chr2_+_161993412 0.17 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr11_+_128562372 0.17 ENST00000344954.6
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_61697862 0.17 ENST00000398571.2
ubiquitin specific peptidase 34
chr8_-_40755333 0.17 ENST00000297737.6
ENST00000315769.7
zinc finger, matrin-type 4
chr5_-_111092873 0.17 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr5_-_179045199 0.17 ENST00000523921.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr4_+_129730779 0.17 ENST00000226319.6
jade family PHD finger 1
chr5_-_130868688 0.17 ENST00000504575.1
ENST00000513227.1
Rap guanine nucleotide exchange factor (GEF) 6
chr11_-_10530723 0.17 ENST00000536684.1
MT-RNR2-like 8
chr17_-_27333163 0.17 ENST00000360295.9
seizure related 6 homolog (mouse)
chr5_-_90679145 0.17 ENST00000265138.3
arrestin domain containing 3
chr8_+_26150628 0.17 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr8_-_80993010 0.17 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr12_+_79258547 0.16 ENST00000457153.2
synaptotagmin I
chr7_+_129015671 0.16 ENST00000466993.1
adenosylhomocysteinase-like 2
chr14_-_35099315 0.16 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
sorting nexin 6
chr8_-_124279627 0.16 ENST00000357082.4
ZHX1-C8ORF76 readthrough
chr18_+_20494078 0.16 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr18_-_53089723 0.16 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr3_-_196911002 0.16 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr11_-_10822029 0.16 ENST00000528839.1
eukaryotic translation initiation factor 4 gamma, 2
chr12_-_86230315 0.16 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr15_+_80351910 0.16 ENST00000261749.6
ENST00000561060.1
zinc finger, AN1-type domain 6

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.8 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.2 GO:0061348 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) melanocyte proliferation(GO:0097325) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 1.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0032431 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:1902714 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) negative regulation of interferon-gamma secretion(GO:1902714) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.0 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:2001202 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.0 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.0 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.0 GO:0002725 regulation of tolerance induction dependent upon immune response(GO:0002652) positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.0 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310) regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0071953 elastic fiber(GO:0071953)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.4 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 2.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation