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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXD10

Z-value: 0.92

Motif logo

Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.5 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_176981307-0.434.0e-01Click!

Activity profile of HOXD10 motif

Sorted Z-values of HOXD10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_57671888 0.96 ENST00000391612.1
AL391152.1
chr12_+_20963647 0.84 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chrM_+_10464 0.73 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_172309634 0.70 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr1_+_223354486 0.68 ENST00000446145.1
RP11-239E10.3
chr8_-_90993869 0.65 ENST00000517772.1
nibrin
chr2_-_187367356 0.62 ENST00000595956.1
AC018867.2
chr12_+_20963632 0.61 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr5_-_95550754 0.56 ENST00000502437.1
RP11-254I22.3
chr1_+_79115503 0.56 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr13_+_76378305 0.54 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr10_-_52008313 0.54 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr4_+_155484155 0.49 ENST00000509493.1
fibrinogen beta chain
chr18_-_68004529 0.48 ENST00000578633.1
RP11-484N16.1
chr11_+_74204883 0.46 ENST00000528481.1
polymerase (DNA-directed), delta 3, accessory subunit
chr12_-_100656134 0.46 ENST00000548313.1
DEP domain containing 4
chr17_+_48823896 0.45 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr4_-_112993808 0.45 ENST00000511219.1
RP11-269F21.3
chrM_+_8366 0.43 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr18_+_48918368 0.43 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
chr12_-_10324716 0.43 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_76944621 0.41 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr12_-_10022735 0.40 ENST00000228438.2
C-type lectin domain family 2, member B
chr1_+_207277632 0.39 ENST00000421786.1
complement component 4 binding protein, alpha
chr3_+_136649311 0.38 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr12_-_92536433 0.37 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr8_+_124084899 0.36 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr1_-_101360331 0.35 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr18_+_20494078 0.35 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr8_+_62200509 0.34 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
clavesin 1
chr5_+_39105358 0.33 ENST00000593965.1
AC008964.1
chr1_-_238108575 0.33 ENST00000604646.1
MT-RNR2-like 11 (pseudogene)
chr21_+_25801041 0.33 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr2_+_187371440 0.33 ENST00000445547.1
zinc finger CCCH-type containing 15
chr5_+_167913450 0.32 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr18_-_61329118 0.32 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr4_+_130017268 0.32 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr7_-_108168580 0.32 ENST00000453085.1
patatin-like phospholipase domain containing 8
chr9_+_42671887 0.32 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr2_+_183582774 0.32 ENST00000537515.1
DnaJ (Hsp40) homolog, subfamily C, member 10
chr8_+_74903580 0.31 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr1_-_101360374 0.31 ENST00000535414.1
exostosin-like glycosyltransferase 2
chr4_+_76649797 0.31 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr6_-_135375921 0.31 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1-like (S. cerevisiae)
chr7_+_135611542 0.30 ENST00000416501.1
AC015987.2
chr15_+_42566384 0.30 ENST00000440615.2
ENST00000318010.8
glucosidase, alpha; neutral C
chr3_+_158288960 0.30 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
myeloid leukemia factor 1
chr10_+_94594351 0.30 ENST00000371552.4
exocyst complex component 6
chr1_+_186798073 0.29 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_-_100016527 0.29 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
cyclin C
chr1_-_242612726 0.29 ENST00000459864.1
phospholipase D family, member 5
chr1_+_87458692 0.28 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr18_-_10701979 0.27 ENST00000538948.1
ENST00000285141.4
piezo-type mechanosensitive ion channel component 2
chr11_-_126174186 0.27 ENST00000524964.1
Uncharacterized protein
chr1_-_111743285 0.27 ENST00000357640.4
DENN/MADD domain containing 2D
chr19_-_6690723 0.27 ENST00000601008.1
complement component 3
chr11_-_27528301 0.27 ENST00000524596.1
ENST00000278193.2
lin-7 homolog C (C. elegans)
chr9_-_104145795 0.27 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr14_-_82089405 0.26 ENST00000554211.1
RP11-799P8.1
chr1_+_207277590 0.26 ENST00000367070.3
complement component 4 binding protein, alpha
chr1_-_33642151 0.26 ENST00000543586.1
tripartite motif containing 62
chr6_-_135375986 0.26 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1-like (S. cerevisiae)
chr14_-_50506589 0.25 ENST00000553914.2
RP11-58E21.3
chrX_-_138914394 0.25 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr2_+_118572226 0.25 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_+_158288999 0.24 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
myeloid leukemia factor 1
chr10_-_115614127 0.24 ENST00000369305.1
DNA cross-link repair 1A
chr3_+_158288942 0.24 ENST00000491767.1
ENST00000355893.5
myeloid leukemia factor 1
chr2_-_165424973 0.24 ENST00000543549.1
growth factor receptor-bound protein 14
chr8_+_82066514 0.23 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
chr16_-_90096309 0.23 ENST00000408886.2
chromosome 16 open reading frame 3
chr7_+_116451100 0.23 ENST00000464223.1
ENST00000484325.1
capping protein (actin filament) muscle Z-line, alpha 2
chr14_+_56127960 0.23 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr2_-_211341411 0.23 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr4_+_86748898 0.22 ENST00000509300.1
Rho GTPase activating protein 24
chr8_-_124279627 0.22 ENST00000357082.4
ZHX1-C8ORF76 readthrough
chr2_+_86333340 0.22 ENST00000409783.2
ENST00000409277.3
pentatricopeptide repeat domain 3
chr1_+_52521957 0.22 ENST00000472944.2
ENST00000484036.1
basic transcription factor 3-like 4
chr13_+_76378357 0.22 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr1_+_162467595 0.22 ENST00000538489.1
ENST00000489294.1
U2AF homology motif (UHM) kinase 1
chr16_+_21623392 0.22 ENST00000562961.1
methyltransferase like 9
chr3_+_108015382 0.22 ENST00000463019.3
ENST00000491820.1
ENST00000467562.1
ENST00000482430.1
ENST00000462629.1
HERV-H LTR-associating 2
chr12_+_79258547 0.22 ENST00000457153.2
synaptotagmin I
chr11_-_64703354 0.22 ENST00000532246.1
ENST00000279168.2
glycoprotein hormone alpha 2
chr13_+_33160553 0.21 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_+_47630255 0.21 ENST00000406134.1
mutS homolog 2
chr3_+_171561127 0.21 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr14_+_73563735 0.21 ENST00000532192.1
RNA binding motif protein 25
chr3_+_69811858 0.21 ENST00000433517.1
microphthalmia-associated transcription factor
chr4_+_86749045 0.21 ENST00000514229.1
Rho GTPase activating protein 24
chr2_-_165698662 0.21 ENST00000194871.6
ENST00000445474.2
cordon-bleu WH2 repeat protein-like 1
chr11_+_46332679 0.21 ENST00000530518.1
cAMP responsive element binding protein 3-like 1
chr2_+_183982238 0.21 ENST00000442895.2
ENST00000446612.1
ENST00000409798.1
nucleoporin 35kDa
chr14_-_57960456 0.20 ENST00000534126.1
ENST00000422976.2
chromosome 14 open reading frame 105
chr4_+_76481258 0.20 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr1_-_149459549 0.20 ENST00000369175.3
family with sequence similarity 72, member C
chrX_-_102943022 0.20 ENST00000433176.2
mortality factor 4 like 2
chr1_+_158978768 0.20 ENST00000447473.2
interferon, gamma-inducible protein 16
chrM_+_10053 0.19 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr1_+_52521797 0.19 ENST00000313334.8
basic transcription factor 3-like 4
chr4_+_78804393 0.19 ENST00000502384.1
mitochondrial ribosomal protein L1
chr3_-_120461378 0.19 ENST00000273375.3
RAB, member of RAS oncogene family-like 3
chr5_-_36152031 0.19 ENST00000296603.4
LMBR1 domain containing 2
chr15_-_32747103 0.19 ENST00000562377.1
golgin A8 family, member O
chr10_-_37891859 0.19 ENST00000544824.1
MT-RNR2-like 7
chr13_+_78109804 0.19 ENST00000535157.1
sciellin
chr8_+_26150628 0.19 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr2_+_234590556 0.19 ENST00000373426.3
UDP glucuronosyltransferase 1 family, polypeptide A7
chr16_-_30122717 0.19 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr3_-_185641681 0.18 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr7_+_112262421 0.18 ENST00000453459.1
AC002463.3
chr5_+_145583107 0.18 ENST00000506502.1
RNA binding motif protein 27
chr18_+_3252265 0.18 ENST00000580887.1
ENST00000536605.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_-_91546926 0.18 ENST00000550758.1
decorin
chr1_+_84630574 0.18 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_183580954 0.18 ENST00000264065.7
DnaJ (Hsp40) homolog, subfamily C, member 10
chr10_+_124739964 0.18 ENST00000406217.2
phosphoseryl-tRNA kinase
chr5_-_111754948 0.18 ENST00000261486.5
erythrocyte membrane protein band 4.1 like 4A
chr5_-_58882219 0.18 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chr1_-_54405773 0.18 ENST00000371376.1
heat shock protein family B (small), member 11
chr4_+_178649911 0.17 ENST00000507870.1
long intergenic non-protein coding RNA 1098
chr5_+_54603566 0.17 ENST00000230640.5
superkiller viralicidic activity 2-like 2 (S. cerevisiae)
chr13_-_50367057 0.17 ENST00000261667.3
karyopherin alpha 3 (importin alpha 4)
chr6_-_76072719 0.17 ENST00000370020.1
filamin A interacting protein 1
chr6_+_145118873 0.17 ENST00000432686.1
ENST00000417142.1
utrophin
chr8_-_66701319 0.17 ENST00000379419.4
phosphodiesterase 7A
chr9_-_125240235 0.17 ENST00000259357.2
olfactory receptor, family 1, subfamily J, member 1
chr1_+_78470530 0.17 ENST00000370763.5
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_+_77469439 0.17 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr8_-_112248400 0.17 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr10_+_60094735 0.16 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr3_+_44666519 0.16 ENST00000344387.4
ENST00000383745.2
zinc finger protein 197
chr5_-_111312622 0.16 ENST00000395634.3
neuronal regeneration related protein
chr4_+_117220016 0.16 ENST00000604093.1
MT-RNR2-like 13 (pseudogene)
chr15_-_52263937 0.16 ENST00000315141.5
ENST00000299601.5
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr5_-_39203093 0.16 ENST00000515010.1
FYN binding protein
chr9_-_75653627 0.16 ENST00000446946.1
aldehyde dehydrogenase 1 family, member A1
chr3_-_27498235 0.16 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr9_+_108006880 0.16 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
solute carrier family 44 (choline transporter), member 1
chr5_-_96518907 0.16 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr5_-_122759032 0.15 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
centrosomal protein 120kDa
chr4_-_185694872 0.15 ENST00000505492.1
acyl-CoA synthetase long-chain family member 1
chr20_-_55934878 0.15 ENST00000543500.1
MT-RNR2-like 3
chr5_-_43557129 0.15 ENST00000514514.1
ENST00000504075.1
ENST00000306846.3
ENST00000436644.2
poly(A) binding protein interacting protein 1
chr8_+_77318769 0.15 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr1_+_164528866 0.15 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr13_+_78109884 0.15 ENST00000377246.3
ENST00000349847.3
sciellin
chr5_+_162930114 0.15 ENST00000280969.5
methionine adenosyltransferase II, beta
chr6_-_134639180 0.15 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr3_+_130569429 0.15 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr16_-_79804394 0.14 ENST00000567993.1
RP11-345M22.2
chr12_+_14561422 0.14 ENST00000541056.1
activating transcription factor 7 interacting protein
chr1_-_101360205 0.14 ENST00000450240.1
exostosin-like glycosyltransferase 2
chr9_-_36401155 0.14 ENST00000377885.2
ring finger protein 38
chr2_+_86333301 0.14 ENST00000254630.7
pentatricopeptide repeat domain 3
chr8_+_35649365 0.14 ENST00000437887.1
Uncharacterized protein
chr12_-_16760021 0.14 ENST00000540445.1
LIM domain only 3 (rhombotin-like 2)
chr6_-_88299678 0.14 ENST00000369536.5
arginyl-tRNA synthetase 2, mitochondrial
chr17_-_4463856 0.13 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr12_-_76817036 0.13 ENST00000546946.1
oxysterol binding protein-like 8
chr11_+_112130988 0.13 ENST00000595053.1
LOC100132686 protein; Uncharacterized protein
chr2_+_234875252 0.13 ENST00000456930.1
transient receptor potential cation channel, subfamily M, member 8
chrX_+_119737806 0.13 ENST00000371317.5
malignant T cell amplified sequence 1
chr7_-_22233442 0.13 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr11_-_104905840 0.13 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr2_+_196440692 0.13 ENST00000458054.1
solute carrier family 39 (zinc transporter), member 10
chr5_-_77590480 0.13 ENST00000519295.1
ENST00000255194.6
adaptor-related protein complex 3, beta 1 subunit
chr12_-_12674032 0.13 ENST00000298573.4
dual specificity phosphatase 16
chr3_+_160559931 0.13 ENST00000464260.1
ENST00000295839.9
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr17_-_67264947 0.13 ENST00000586811.1
ATP-binding cassette, sub-family A (ABC1), member 5
chr19_-_44388116 0.13 ENST00000587539.1
zinc finger protein 404
chr3_+_69788576 0.13 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr15_+_69373184 0.13 ENST00000558147.1
ENST00000440444.1
long intergenic non-protein coding RNA 277
chr2_+_210444748 0.12 ENST00000392194.1
microtubule-associated protein 2
chrX_-_102942961 0.12 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
mortality factor 4 like 2
chr2_+_29353520 0.12 ENST00000438819.1
CAP-GLY domain containing linker protein family, member 4
chr10_+_35456444 0.12 ENST00000361599.4
cAMP responsive element modulator
chr6_+_121756809 0.12 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr1_-_86848760 0.12 ENST00000460698.2
outer dense fiber of sperm tails 2-like
chr12_-_10588539 0.12 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr8_-_28347737 0.12 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
F-box protein 16
chr6_-_150067632 0.12 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
nucleoporin 43kDa
chr9_-_130517522 0.12 ENST00000373274.3
ENST00000420366.1
SH2 domain containing 3C
chr11_-_93271058 0.12 ENST00000527149.1
single-pass membrane protein with coiled-coil domains 4
chr15_+_57511609 0.12 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
transcription factor 12
chr17_+_15604513 0.12 ENST00000481540.1
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr6_-_8102714 0.12 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr2_-_190627481 0.12 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
O-sialoglycoprotein endopeptidase-like 1
chr18_+_61445007 0.12 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_+_38217920 0.12 ENST00000396013.1
ENST00000440144.1
ENST00000453225.1
ENST00000429075.1
STARD3 N-terminal like
chr7_+_151038850 0.12 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
negative regulator of ubiquitin-like proteins 1
chr1_-_156399184 0.12 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr10_-_104913367 0.12 ENST00000423468.2
5'-nucleotidase, cytosolic II
chr12_+_85430110 0.12 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chr1_+_170501270 0.11 ENST00000367763.3
ENST00000367762.1
golgin, RAB6-interacting
chrX_-_19988382 0.11 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr4_-_70080449 0.11 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chrX_-_154493791 0.11 ENST00000369454.3
RAB39B, member RAS oncogene family
chr8_+_61822605 0.11 ENST00000526936.1
AC022182.1
chr6_+_96025341 0.11 ENST00000369293.1
ENST00000358812.4
mannosidase, endo-alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.3 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.3 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.3 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:2000987 cell communication by chemical coupling(GO:0010643) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.3 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.0 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.2 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 1.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation