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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSF4

Z-value: 1.11

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Transcription factors associated with HSF4

Gene Symbol Gene ID Gene Info
HSF4
ENSG00000102878.11 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSF4hg19_v2_chr16_+_67198683_67198715-0.739.8e-02Click!

Activity profile of HSF4 motif

Sorted Z-values of HSF4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 1.08 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr13_-_31736132 0.89 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr14_-_102553371 0.69 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr17_+_45401308 0.68 ENST00000331493.2
ENST00000519772.1
ENST00000517484.1
EFCAB13
EF-hand calcium binding domain 13
chr13_-_31736478 0.64 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr7_-_139763521 0.63 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr6_-_106773291 0.60 ENST00000343245.3
ATG5
autophagy related 5
chr1_+_92683467 0.58 ENST00000370375.3
ENST00000370373.2
C1orf146
chromosome 1 open reading frame 146
chrX_+_123094672 0.57 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr7_+_26240776 0.57 ENST00000337620.4
CBX3
chromobox homolog 3
chr13_-_31736027 0.56 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chrX_+_108780062 0.56 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr12_-_110939870 0.53 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr13_-_31191642 0.52 ENST00000405805.1
HMGB1
high mobility group box 1
chr1_-_245026388 0.52 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_-_53080644 0.52 ENST00000497586.1
SFMBT1
Scm-like with four mbt domains 1
chr13_+_31191920 0.51 ENST00000255304.4
USPL1
ubiquitin specific peptidase like 1
chr11_-_89956461 0.51 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr2_+_198365095 0.50 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr17_+_74723031 0.49 ENST00000586200.1
METTL23
methyltransferase like 23
chr7_+_56119323 0.49 ENST00000275603.4
ENST00000335503.3
ENST00000540286.1
CCT6A
chaperonin containing TCP1, subunit 6A (zeta 1)
chrX_+_123094369 0.47 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr19_-_6720686 0.47 ENST00000245907.6
C3
complement component 3
chr9_-_6015607 0.47 ENST00000259569.5
RANBP6
RAN binding protein 6
chrX_+_54947229 0.47 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr5_+_159895275 0.46 ENST00000517927.1
MIR146A
microRNA 146a
chr9_+_33025209 0.46 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_+_44679370 0.46 ENST00000372290.4
DMAP1
DNA methyltransferase 1 associated protein 1
chr10_-_74856608 0.45 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr18_-_71815051 0.45 ENST00000582526.1
ENST00000419743.2
FBXO15
F-box protein 15
chr12_+_41136144 0.43 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr5_+_133707252 0.43 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr11_-_111781554 0.42 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr1_+_156308403 0.42 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr18_+_9136758 0.42 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12
ankyrin repeat domain 12
chr5_+_56469843 0.41 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr12_-_110883346 0.40 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_-_89956227 0.39 ENST00000457199.2
ENST00000530765.1
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr13_+_95254085 0.39 ENST00000376958.4
GPR180
G protein-coupled receptor 180
chr7_+_157129738 0.38 ENST00000437030.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr21_-_40720974 0.38 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr14_-_81425828 0.38 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr11_-_82997420 0.38 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr12_-_48500085 0.38 ENST00000549518.1
SENP1
SUMO1/sentrin specific peptidase 1
chr2_+_198365122 0.37 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr1_-_149459549 0.35 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr11_+_28724129 0.34 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr11_-_82997013 0.34 ENST00000529073.1
ENST00000529611.1
CCDC90B
coiled-coil domain containing 90B
chr21_-_30445886 0.34 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr5_-_133706695 0.34 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr12_+_70132458 0.34 ENST00000247833.7
RAB3IP
RAB3A interacting protein
chr1_-_228613026 0.33 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr12_+_50794891 0.33 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr21_+_35445827 0.33 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr11_-_122932730 0.33 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8
heat shock 70kDa protein 8
chr3_+_186501336 0.33 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2
eukaryotic translation initiation factor 4A2
chr14_+_101293687 0.33 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr11_-_14913765 0.32 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr12_+_104324112 0.32 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr11_-_82997371 0.32 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr17_+_33474826 0.32 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr11_+_65266507 0.32 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr12_-_123011536 0.32 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr2_-_69664586 0.31 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr5_+_56469939 0.31 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr17_+_45401139 0.31 ENST00000517310.1
EFCAB13
EF-hand calcium binding domain 13
chrX_+_123095155 0.30 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr20_+_10015678 0.30 ENST00000378392.1
ENST00000378380.3
ANKEF1
ankyrin repeat and EF-hand domain containing 1
chr12_+_70132632 0.30 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3IP
RAB3A interacting protein
chrX_+_108779870 0.29 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr12_-_123011476 0.28 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr9_+_74764340 0.28 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chrX_-_102943022 0.28 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chr2_-_198364581 0.27 ENST00000428204.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr21_+_35445811 0.27 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr17_+_33474860 0.27 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chrX_-_80377162 0.27 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr2_-_62115725 0.26 ENST00000538252.1
ENST00000544079.1
ENST00000394440.3
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr5_+_118690466 0.26 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr1_+_161494036 0.26 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr13_-_41593425 0.26 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_203130439 0.26 ENST00000264279.5
NOP58
NOP58 ribonucleoprotein
chr17_-_40168698 0.26 ENST00000590774.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr2_+_210444142 0.25 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr14_-_52535712 0.25 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr11_+_86013253 0.25 ENST00000533986.1
ENST00000278483.3
C11orf73
chromosome 11 open reading frame 73
chr5_+_133706865 0.25 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr15_+_79165151 0.24 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr7_-_151107767 0.24 ENST00000477459.1
WDR86
WD repeat domain 86
chr1_-_242162375 0.24 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr7_-_1199781 0.24 ENST00000397083.1
ENST00000401903.1
ENST00000316495.3
ZFAND2A
zinc finger, AN1-type domain 2A
chr5_+_56469775 0.24 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr15_+_79165112 0.24 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr1_+_156308245 0.24 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr4_-_185269050 0.24 ENST00000511465.1
RP11-290F5.2
RP11-290F5.2
chr2_-_62115659 0.24 ENST00000544185.1
CCT4
chaperonin containing TCP1, subunit 4 (delta)
chr8_+_140943416 0.24 ENST00000507535.3
C8orf17
chromosome 8 open reading frame 17
chr2_+_201170999 0.23 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_-_106243451 0.23 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr1_-_6260896 0.23 ENST00000497965.1
RPL22
ribosomal protein L22
chr1_-_26232522 0.23 ENST00000399728.1
STMN1
stathmin 1
chr17_+_74722912 0.23 ENST00000589977.1
ENST00000591571.1
ENST00000592849.1
ENST00000586738.1
ENST00000588783.1
ENST00000588563.1
ENST00000586752.1
ENST00000588302.1
ENST00000590964.1
ENST00000341249.6
ENST00000588822.1
METTL23
methyltransferase like 23
chr11_-_111781610 0.22 ENST00000525823.1
CRYAB
crystallin, alpha B
chr4_-_129491686 0.22 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr2_+_201171268 0.22 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr15_+_44092784 0.22 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr5_-_10249990 0.21 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chrX_-_102942961 0.21 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2
mortality factor 4 like 2
chr11_+_107799118 0.21 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr11_-_134123142 0.20 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr3_+_130613001 0.20 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_+_157129660 0.20 ENST00000429029.2
ENST00000262177.4
ENST00000417758.1
ENST00000452797.2
ENST00000443280.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr8_-_81083618 0.20 ENST00000520795.1
TPD52
tumor protein D52
chr21_-_40720995 0.20 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chrX_-_106243294 0.20 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr2_-_68479614 0.19 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr7_-_100493744 0.19 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr8_+_62200509 0.19 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1
clavesin 1
chr14_+_63671105 0.19 ENST00000316754.3
RHOJ
ras homolog family member J
chr15_+_79165222 0.19 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr11_-_122933043 0.19 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8
heat shock 70kDa protein 8
chrX_-_80377118 0.19 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr11_+_10772847 0.19 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr12_-_76817036 0.19 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr22_-_41252962 0.18 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr6_+_44215603 0.18 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr14_+_96722539 0.18 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr4_-_159644507 0.17 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr22_+_29168652 0.17 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr2_-_238499131 0.17 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr3_+_130613226 0.17 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr19_-_49567124 0.16 ENST00000301411.3
NTF4
neurotrophin 4
chr10_-_62332357 0.16 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_25865159 0.15 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr19_-_49565254 0.15 ENST00000593537.1
NTF4
neurotrophin 4
chrX_-_154563889 0.15 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr17_-_61850894 0.15 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr20_+_36149602 0.15 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr12_+_65563329 0.14 ENST00000308330.2
LEMD3
LEM domain containing 3
chr19_-_2308127 0.14 ENST00000404279.1
LINGO3
leucine rich repeat and Ig domain containing 3
chrX_-_43741594 0.14 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr4_+_5527117 0.13 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr8_-_81083731 0.13 ENST00000379096.5
TPD52
tumor protein D52
chr11_-_111781454 0.13 ENST00000533280.1
CRYAB
crystallin, alpha B
chr5_+_74062806 0.13 ENST00000296802.5
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr19_-_55836669 0.13 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chrX_-_20236970 0.13 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr3_-_130746462 0.12 ENST00000505545.1
ASTE1
asteroid homolog 1 (Drosophila)
chr1_+_202183200 0.12 ENST00000439764.2
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr2_-_69180083 0.11 ENST00000328895.4
GKN2
gastrokine 2
chr5_+_421030 0.11 ENST00000506456.1
AHRR
aryl-hydrocarbon receptor repressor
chr9_+_109685630 0.11 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr19_-_474880 0.11 ENST00000382696.3
ENST00000315489.4
ODF3L2
outer dense fiber of sperm tails 3-like 2
chr17_+_34087888 0.11 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50
chromosome 17 open reading frame 50
chr19_-_17958832 0.11 ENST00000458235.1
JAK3
Janus kinase 3
chr14_-_36536396 0.10 ENST00000546376.1
RP11-116N8.4
RP11-116N8.4
chr18_-_6929829 0.10 ENST00000583840.1
ENST00000581571.1
ENST00000578497.1
ENST00000579012.1
LINC00668
long intergenic non-protein coding RNA 668
chr17_-_74137374 0.10 ENST00000322957.6
FOXJ1
forkhead box J1
chr1_+_154947148 0.10 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr12_+_50794947 0.10 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr22_-_24181174 0.10 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chr9_-_86323118 0.09 ENST00000376395.4
UBQLN1
ubiquilin 1
chr7_-_3083573 0.09 ENST00000396946.4
CARD11
caspase recruitment domain family, member 11
chr18_+_57567180 0.09 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr9_-_86322831 0.09 ENST00000257468.7
UBQLN1
ubiquilin 1
chr9_-_4666337 0.09 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr3_+_130612803 0.09 ENST00000510168.1
ENST00000508532.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr11_-_47870019 0.09 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr3_+_101443476 0.08 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr1_+_154947126 0.08 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr15_+_96869165 0.08 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr22_+_50986462 0.08 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr3_+_186501979 0.08 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr1_-_45987526 0.08 ENST00000372079.1
ENST00000262746.1
ENST00000447184.1
ENST00000319248.8
PRDX1
peroxiredoxin 1
chr22_+_31460091 0.08 ENST00000432777.1
ENST00000422839.1
SMTN
smoothelin
chr17_+_44701402 0.07 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr15_-_58357866 0.07 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr10_-_21186144 0.07 ENST00000377119.1
NEBL
nebulette
chr12_-_4754318 0.07 ENST00000536414.1
AKAP3
A kinase (PRKA) anchor protein 3
chr4_-_22517620 0.07 ENST00000502482.1
ENST00000334304.5
GPR125
G protein-coupled receptor 125
chr17_-_8286484 0.07 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr1_-_53704157 0.07 ENST00000371466.4
ENST00000371470.3
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr12_-_4754356 0.07 ENST00000540967.1
AKAP3
A kinase (PRKA) anchor protein 3
chr3_-_183735651 0.07 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_+_112046190 0.07 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2
beta-carotene oxygenase 2
chr12_-_108154705 0.07 ENST00000547188.1
PRDM4
PR domain containing 4
chr11_+_63953691 0.06 ENST00000543847.1
STIP1
stress-induced-phosphoprotein 1
chr21_+_45937497 0.06 ENST00000354333.5
C21orf90
chromosome 21 open reading frame 90
chr9_-_86593238 0.06 ENST00000351839.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chrX_-_152939252 0.06 ENST00000340888.3
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr11_-_47870091 0.06 ENST00000526870.1
NUP160
nucleoporin 160kDa
chr1_-_205904950 0.06 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chrX_-_152939133 0.05 ENST00000370150.1
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr3_+_136676851 0.05 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr6_+_42531798 0.05 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr22_+_17082732 0.05 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr2_-_198364552 0.05 ENST00000439605.1
ENST00000418022.1
HSPD1
heat shock 60kDa protein 1 (chaperonin)
chr17_-_9963091 0.05 ENST00000578599.1
GAS7
growth arrest-specific 7
chr15_-_51610687 0.05 ENST00000559646.1
CYP19A1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr9_-_88714421 0.05 ENST00000388712.3
GOLM1
golgi membrane protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HSF4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 2.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 0.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.7 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.8 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.1 0.7 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.3 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.5 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.6 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 1.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 1.1 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.2 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.3 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 1.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 2.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.3 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.9 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins