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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSFY2

Z-value: 1.65

Motif logo

Transcription factors associated with HSFY2

Gene Symbol Gene ID Gene Info
ENSG00000169953.11 heat shock transcription factor Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HSFY2hg19_v2_chrY_-_20935572_20935621-0.493.2e-01Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_62203808 1.73 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chr3_-_129375556 1.13 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr3_-_146262365 1.00 ENST00000448787.2
phospholipid scramblase 1
chr3_-_146262352 0.95 ENST00000462666.1
phospholipid scramblase 1
chr12_+_9102632 0.91 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr10_+_35416223 0.80 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr11_+_5646213 0.79 ENST00000429814.2
tripartite motif containing 34
chr18_-_61329118 0.79 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr13_+_76378357 0.76 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr3_-_146262293 0.73 ENST00000448205.1
phospholipid scramblase 1
chr1_+_155583012 0.72 ENST00000462250.2
misato 1, mitochondrial distribution and morphology regulator
chr7_-_32338917 0.70 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr3_-_146262428 0.70 ENST00000486631.1
phospholipid scramblase 1
chr11_+_34654011 0.65 ENST00000531794.1
ets homologous factor
chr17_+_68165657 0.64 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_-_89458415 0.63 ENST00000321792.5
ENST00000370491.3
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr5_+_76114758 0.59 ENST00000514165.1
ENST00000296677.4
coagulation factor II (thrombin) receptor-like 1
chr10_-_104866395 0.57 ENST00000458345.1
5'-nucleotidase, cytosolic II
chr3_+_122044084 0.55 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr14_+_32476072 0.55 ENST00000556949.1
Uncharacterized protein
chr11_+_17281900 0.54 ENST00000530527.1
nucleobindin 2
chr17_+_76311791 0.53 ENST00000586321.1
AC061992.2
chr20_+_10199468 0.53 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr13_+_76378305 0.52 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr12_+_113376157 0.50 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr16_+_21312170 0.50 ENST00000338573.5
ENST00000561968.1
CRYM antisense RNA 1
chr3_+_122399444 0.48 ENST00000474629.2
poly (ADP-ribose) polymerase family, member 14
chr7_-_102789503 0.47 ENST00000465647.1
ENST00000418294.1
N-acyl phosphatidylethanolamine phospholipase D
chr16_+_9056563 0.47 ENST00000564485.1
RP11-77H9.8
chr2_-_201753717 0.45 ENST00000409264.2
peptidylprolyl isomerase (cyclophilin)-like 3
chr20_+_10199566 0.44 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr10_-_14574705 0.44 ENST00000489100.1
family with sequence similarity 107, member B
chr2_+_54198210 0.44 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr14_-_23762777 0.43 ENST00000431326.2
homeobox and leucine zipper encoding
chr1_+_158979680 0.43 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr15_-_80263506 0.43 ENST00000335661.6
BCL2-related protein A1
chr10_+_35416090 0.42 ENST00000354759.3
cAMP responsive element modulator
chr13_-_33112823 0.42 ENST00000504114.1
NEDD4 binding protein 2-like 2
chr3_-_111852061 0.41 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
germinal center-associated, signaling and motility
chr1_+_196788887 0.41 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr12_+_100897130 0.41 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr1_-_150207017 0.40 ENST00000369119.3
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_+_158979686 0.39 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr5_+_111496631 0.39 ENST00000508590.1
EPB41L4A antisense RNA 1
chr13_+_25875785 0.38 ENST00000381747.3
nucleoporin like 1
chr2_+_238877424 0.38 ENST00000434655.1
ubiquitin-conjugating enzyme E2F (putative)
chr15_-_57025728 0.37 ENST00000559352.1
zinc finger protein 280D
chr5_-_133706695 0.37 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr1_-_67142710 0.37 ENST00000502413.2
Uncharacterized protein
chr15_+_57891609 0.35 ENST00000569089.1
myocardial zonula adherens protein
chr2_+_46926048 0.35 ENST00000306503.5
suppressor of cytokine signaling 5
chr10_-_131640435 0.35 ENST00000440978.1
early B-cell factor 3
chr3_-_148804275 0.35 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr14_+_62164340 0.35 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr22_-_36031181 0.35 ENST00000594060.1
AL049747.1
chr12_+_85430110 0.35 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chr1_+_209859510 0.34 ENST00000367028.2
ENST00000261465.1
hydroxysteroid (11-beta) dehydrogenase 1
chr10_-_36812323 0.34 ENST00000543053.1
nicotinamide phosphoribosyltransferase-like
chr8_+_38089198 0.34 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr5_+_68860949 0.34 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr17_-_4889508 0.34 ENST00000574606.2
calmodulin binding transcription activator 2
chr14_-_106114739 0.33 ENST00000460164.1
RP11-731F5.2
chr11_+_73661364 0.33 ENST00000339764.1
DnaJ (Hsp40) homolog, subfamily B, member 13
chr10_+_7745232 0.33 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_35415851 0.33 ENST00000374726.3
cAMP responsive element modulator
chr7_-_95025661 0.32 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
paraoxonase 1
paraoxonase 3
chr2_-_201753980 0.32 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
peptidylprolyl isomerase (cyclophilin)-like 3
chr3_+_138067314 0.32 ENST00000423968.2
muscle RAS oncogene homolog
chr13_-_33112899 0.32 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
NEDD4 binding protein 2-like 2
chr18_+_3247779 0.32 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr6_-_169582835 0.32 ENST00000564830.1
RP11-417E7.2
chr8_+_124084899 0.31 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1 domain family, member 31
chr15_+_89181974 0.31 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr1_-_94344754 0.31 ENST00000436063.2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr2_+_74056147 0.31 ENST00000394070.2
ENST00000536064.1
STAM binding protein
chr6_-_155635583 0.31 ENST00000367166.4
transcription factor B1, mitochondrial
chr10_+_7745303 0.30 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_88535747 0.30 ENST00000309041.7
centrosomal protein 290kDa
chr22_-_32341336 0.30 ENST00000248984.3
chromosome 22 open reading frame 24
chr9_+_95820966 0.30 ENST00000375472.3
ENST00000465709.1
sushi domain containing 3
chr6_-_26285737 0.29 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr8_+_48920960 0.29 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr10_+_106113515 0.29 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chr18_-_37380230 0.29 ENST00000591629.1
long intergenic non-protein coding RNA 669
chr13_+_27825706 0.29 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
ribosomal protein L21
chr10_-_33281363 0.29 ENST00000534049.1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr11_+_43702236 0.29 ENST00000531185.1
ENST00000278353.4
hydroxysteroid (17-beta) dehydrogenase 12
chr14_-_23395623 0.28 ENST00000556043.1
protein arginine methyltransferase 5
chr1_+_186798073 0.28 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr12_-_12509929 0.28 ENST00000381800.2
loss of heterozygosity, 12, chromosomal region 2 (non-protein coding)
chr14_+_96722539 0.28 ENST00000553356.1
bradykinin receptor B1
chr12_+_95612006 0.28 ENST00000551311.1
ENST00000546445.1
vezatin, adherens junctions transmembrane protein
chr6_+_46661575 0.28 ENST00000450697.1
tudor domain containing 6
chr3_-_69249863 0.28 ENST00000478263.1
ENST00000462512.1
FERM domain containing 4B
chr3_+_23847394 0.28 ENST00000306627.3
ubiquitin-conjugating enzyme E2E 1
chr13_+_114462193 0.27 ENST00000375353.3
transmembrane protein 255B
chr1_-_43282945 0.27 ENST00000537227.1
coiled-coil domain containing 23
chr3_+_3168600 0.27 ENST00000251607.6
ENST00000339437.6
ENST00000280591.6
ENST00000420393.1
tRNA nucleotidyl transferase, CCA-adding, 1
chr11_-_92930556 0.27 ENST00000529184.1
solute carrier family 36 (proton/amino acid symporter), member 4
chr10_+_91061712 0.27 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr20_+_30327063 0.27 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr12_+_96337061 0.27 ENST00000266736.2
amidohydrolase domain containing 1
chr1_-_43282906 0.27 ENST00000372521.4
coiled-coil domain containing 23
chr15_+_89182156 0.27 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr21_-_40720974 0.27 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr6_-_64029879 0.27 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
lengsin, lens protein with glutamine synthetase domain
chr4_+_26324474 0.26 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_89458287 0.26 ENST00000370485.2
cysteine conjugate-beta lyase 2
chr9_+_128024067 0.26 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
GTPase activating protein and VPS9 domains 1
chr5_+_81601166 0.26 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr8_-_97247759 0.26 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
ubiquinol-cytochrome c reductase binding protein
chr18_+_21033239 0.26 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr1_-_10532531 0.26 ENST00000377036.2
ENST00000377038.3
DNA fragmentation factor, 45kDa, alpha polypeptide
chr2_+_101223490 0.26 ENST00000414647.1
ENST00000424342.1
AC068538.4
chr12_-_80328905 0.26 ENST00000547330.1
protein phosphatase 1, regulatory subunit 12A
chr6_+_24777040 0.26 ENST00000378059.3
geminin, DNA replication inhibitor
chr14_-_36789783 0.25 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr19_+_50529212 0.25 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
zinc finger protein 473
chr4_+_146402346 0.25 ENST00000514778.1
ENST00000507594.1
SMAD family member 1
chr14_+_21525981 0.25 ENST00000308227.2
ribonuclease, RNase A family, 8
chr1_+_245027971 0.25 ENST00000610145.1
RP11-11N7.4
chr12_+_107168418 0.25 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr17_+_75137460 0.25 ENST00000587820.1
SEC14-like 1 (S. cerevisiae)
chr2_-_169769787 0.25 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr6_+_107077435 0.24 ENST00000369046.4
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr6_-_114292449 0.24 ENST00000519065.1
histone deacetylase 2
chr6_+_110501621 0.24 ENST00000368930.1
ENST00000307731.1
cell division cycle 40
chr18_+_39535239 0.24 ENST00000585528.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr2_+_192141611 0.24 ENST00000392316.1
myosin IB
chr3_+_48282587 0.24 ENST00000354698.3
ENST00000427617.2
ENST00000412564.1
ENST00000440261.2
zinc finger protein 589
chr4_-_103266355 0.24 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chr18_+_51795774 0.24 ENST00000579534.1
ENST00000406285.3
ENST00000577612.1
ENST00000579434.1
ENST00000583136.1
polymerase (DNA directed) iota
chr13_-_36920615 0.23 ENST00000494062.2
spastic paraplegia 20 (Troyer syndrome)
chr7_+_23637763 0.23 ENST00000410069.1
coiled-coil domain containing 126
chr14_+_39583427 0.23 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
gem (nuclear organelle) associated protein 2
chr4_-_106629796 0.23 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
integrator complex subunit 12
chr15_+_27112058 0.23 ENST00000355395.5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr18_+_61637159 0.23 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr3_-_20227619 0.23 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr6_+_37321748 0.23 ENST00000373479.4
ENST00000394443.4
ring finger protein 8, E3 ubiquitin protein ligase
chr7_-_91509972 0.23 ENST00000425936.1
mitochondrial transcription termination factor
chr3_-_72897545 0.23 ENST00000325599.8
SHQ1, H/ACA ribonucleoprotein assembly factor
chr17_-_46178741 0.23 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr11_+_22646739 0.23 ENST00000428556.2
AC103801.2
chr19_+_17337007 0.22 ENST00000215061.4
occludin/ELL domain containing 1
chr13_-_36920420 0.22 ENST00000438666.2
spastic paraplegia 20 (Troyer syndrome)
chr6_-_26033796 0.22 ENST00000259791.2
histone cluster 1, H2ab
chr18_+_39535152 0.22 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr14_+_35761580 0.22 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr5_-_176433582 0.22 ENST00000506128.1
ubiquitin interaction motif containing 1
chr18_+_9103957 0.22 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr10_+_105881906 0.22 ENST00000369727.3
ENST00000336358.5
SWI5-dependent recombination repair 1
chr14_+_101293687 0.22 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr7_+_86781778 0.21 ENST00000432937.2
cyclin D binding myb-like transcription factor 1
chr1_+_66820058 0.21 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific
chr1_-_93645818 0.21 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr19_-_43690674 0.20 ENST00000342951.6
ENST00000366175.3
pregnancy specific beta-1-glycoprotein 5
chr2_+_196521903 0.20 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr17_+_30469579 0.20 ENST00000354266.3
ENST00000581094.1
ENST00000394692.2
ras homolog family member T1
chr2_-_201753859 0.20 ENST00000409361.1
ENST00000392283.4
peptidylprolyl isomerase (cyclophilin)-like 3
chr1_+_28052518 0.20 ENST00000530324.1
ENST00000234549.7
ENST00000373949.1
ENST00000010299.6
family with sequence similarity 76, member A
chr2_+_70121075 0.20 ENST00000409116.1
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr6_+_107077471 0.20 ENST00000369044.1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr16_-_50402836 0.19 ENST00000394688.3
bromodomain containing 7
chr8_+_27629459 0.19 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr6_-_79944336 0.19 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr8_-_42698292 0.19 ENST00000529779.1
THAP domain containing, apoptosis associated protein 1
chr15_-_57025675 0.19 ENST00000558320.1
zinc finger protein 280D
chr13_-_28024681 0.19 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
mitochondrial translational initiation factor 3
chr11_+_86667117 0.19 ENST00000531827.1
RP11-736K20.6
chr11_+_18477369 0.19 ENST00000396213.3
ENST00000280706.2
lactate dehydrogenase A-like 6A
chr7_-_93520191 0.19 ENST00000545378.1
tissue factor pathway inhibitor 2
chr3_+_49840685 0.19 ENST00000333323.4
family with sequence similarity 212, member A
chr7_+_86781677 0.19 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
cyclin D binding myb-like transcription factor 1
chr7_-_93520259 0.19 ENST00000222543.5
tissue factor pathway inhibitor 2
chr6_-_42185583 0.19 ENST00000053468.3
mitochondrial ribosomal protein S10
chr1_-_26232522 0.19 ENST00000399728.1
stathmin 1
chr10_-_105110890 0.19 ENST00000369847.3
polycomb group ring finger 6
chr13_+_53030107 0.19 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr4_+_79472673 0.18 ENST00000264908.6
annexin A3
chr3_+_141594966 0.18 ENST00000475483.1
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr12_+_95611569 0.18 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr3_+_122399697 0.18 ENST00000494811.1
poly (ADP-ribose) polymerase family, member 14
chr12_-_21910775 0.18 ENST00000539782.1
lactate dehydrogenase B
chr5_-_157286104 0.18 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
clathrin interactor 1
chr5_+_170288856 0.18 ENST00000523189.1
RAN binding protein 17
chrX_-_122866874 0.18 ENST00000245838.8
ENST00000355725.4
THO complex 2
chr12_+_95611516 0.18 ENST00000436874.1
vezatin, adherens junctions transmembrane protein
chr6_-_72129806 0.18 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
long intergenic non-protein coding RNA 472
chr1_-_226496898 0.18 ENST00000481685.1
lin-9 homolog (C. elegans)
chr4_-_113558014 0.18 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
chromosome 4 open reading frame 21
chr11_+_124824000 0.18 ENST00000529051.1
ENST00000344762.5
coiled-coil domain containing 15
chr6_+_122720681 0.18 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr7_-_91509986 0.18 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
mitochondrial transcription termination factor
chr4_-_89079817 0.18 ENST00000505480.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr2_-_10952832 0.17 ENST00000540494.1
protein disulfide isomerase family A, member 6
chr10_+_45495898 0.17 ENST00000298299.3
zinc finger protein 22
chr12_+_86268065 0.17 ENST00000551529.1
ENST00000256010.6
neurotensin
chr11_+_125757556 0.17 ENST00000526028.1
hydrolethalus syndrome 1
chr10_+_76969909 0.17 ENST00000298468.5
ENST00000543351.1
voltage-dependent anion channel 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.2 1.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 0.6 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.2 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.4 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.6 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.1 0.4 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.3 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.7 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.5 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.1 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.3 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.2 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0048369 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 1.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0034699 transforming growth factor beta receptor complex assembly(GO:0007181) response to luteinizing hormone(GO:0034699) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0048793 pronephros development(GO:0048793)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0044782 cilium organization(GO:0044782)
0.0 0.1 GO:2000232 regulation of ribosome biogenesis(GO:0090069) positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.0 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.9 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0034033 coenzyme A metabolic process(GO:0015936) coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.8 GO:0070206 protein trimerization(GO:0070206)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.3 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.6 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 3.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.6 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha