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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF7

Z-value: 2.16

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
IRF7
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615570_6157280.833.9e-02Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91152303 16.95 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_+_948803 11.79 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr14_+_94577074 6.79 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr11_-_615942 5.36 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr11_-_615570 4.46 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr2_-_231084659 4.21 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr8_-_145060593 4.17 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr4_-_169239921 3.35 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_+_79115503 3.34 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr10_+_91092241 3.22 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_+_113344582 2.49 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344755 2.38 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_91087651 2.34 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_-_231084820 2.33 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr12_-_10324716 2.18 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr19_-_17516449 2.11 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr12_+_113416191 2.09 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr2_-_191878162 2.07 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_191878681 2.04 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_191878874 1.93 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr11_-_321050 1.93 ENST00000399808.4
IFITM3
interferon induced transmembrane protein 3
chr9_-_32526184 1.88 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr9_-_32526299 1.87 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr12_+_113416265 1.85 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr3_-_122283079 1.81 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_122283100 1.79 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr4_-_169401628 1.76 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr10_+_91061712 1.64 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr2_-_163175133 1.51 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr2_-_231084617 1.47 ENST00000409815.2
SP110
SP110 nuclear body protein
chr10_+_91174486 1.41 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr1_-_150693318 1.41 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr12_+_113376157 1.40 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr7_-_92777606 1.39 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr9_-_119162885 1.38 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr1_+_158979680 1.37 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr12_+_113376249 1.33 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr4_-_164253738 1.29 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr2_-_37384175 1.29 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr11_+_5646213 1.29 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr11_+_34643600 1.28 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr12_+_113344811 1.21 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_158979686 1.19 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr17_+_28443819 1.18 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr1_+_158979792 1.16 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr3_+_122044084 1.16 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr11_-_64764435 1.16 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr5_-_55777586 1.15 ENST00000506836.1
CTC-236F12.4
Uncharacterized protein
chr3_+_188817891 1.14 ENST00000412373.1
TPRG1
tumor protein p63 regulated 1
chr3_+_122399444 1.10 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr10_+_91174314 1.05 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr17_+_41158742 1.05 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr20_+_10199468 1.05 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr3_+_122283064 1.04 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr9_-_100881466 1.03 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14
tripartite motif containing 14
chr5_-_146461027 1.00 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr17_-_76975925 1.00 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr2_-_7005785 0.99 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr12_-_49463620 0.98 ENST00000550675.1
RHEBL1
Ras homolog enriched in brain like 1
chr11_+_17298522 0.98 ENST00000529313.1
NUCB2
nucleobindin 2
chr2_-_231090344 0.95 ENST00000540870.1
ENST00000416610.1
SP110
SP110 nuclear body protein
chr8_+_27632047 0.94 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr21_+_35107346 0.92 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr7_-_83824449 0.91 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr13_-_86373536 0.90 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr14_-_35183755 0.90 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr17_+_76311791 0.89 ENST00000586321.1
AC061992.2
AC061992.2
chr2_+_202122826 0.87 ENST00000413726.1
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr3_+_122283175 0.87 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr6_-_35888905 0.87 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chrX_+_51486481 0.86 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr15_+_71228826 0.85 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr12_+_72058130 0.82 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr11_+_34663913 0.82 ENST00000532302.1
EHF
ets homologous factor
chr3_-_49851313 0.81 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr17_-_57229155 0.81 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr12_-_7245080 0.79 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chrX_-_119693745 0.79 ENST00000371323.2
CUL4B
cullin 4B
chr1_-_89531041 0.77 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr15_-_80263506 0.77 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr9_+_100174344 0.76 ENST00000422139.2
TDRD7
tudor domain containing 7
chr22_+_36649170 0.76 ENST00000438034.1
ENST00000427990.1
ENST00000347595.7
ENST00000397279.4
ENST00000433768.1
ENST00000440669.2
APOL1
apolipoprotein L, 1
chr12_+_113416340 0.74 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr12_-_7245125 0.74 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chrX_-_20237059 0.73 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr13_+_20532848 0.73 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr11_+_46402583 0.72 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr13_-_33112823 0.72 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr12_-_7245152 0.72 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr11_-_57334732 0.72 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr11_-_77531752 0.72 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr1_-_89488510 0.72 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr19_+_10196781 0.71 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr14_+_24605389 0.71 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_+_79086088 0.70 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr2_-_188419200 0.69 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr14_-_102552659 0.69 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr1_+_186798073 0.69 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_-_17752996 0.69 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr14_-_24615523 0.69 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr13_+_50070077 0.69 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr12_+_7167980 0.68 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr15_+_45003675 0.68 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr9_+_100174232 0.67 ENST00000355295.4
TDRD7
tudor domain containing 7
chr6_+_27925019 0.67 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr2_+_169658928 0.67 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr19_-_53466095 0.67 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
ZNF816
zinc finger protein 816
chr1_-_114429997 0.67 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr12_-_7245018 0.67 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr18_+_3252265 0.66 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_-_62499334 0.65 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr12_-_92536433 0.65 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr1_-_150693305 0.64 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr5_+_82373317 0.63 ENST00000282268.3
ENST00000338635.6
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr11_+_17298543 0.63 ENST00000533926.1
NUCB2
nucleobindin 2
chr3_+_159706537 0.62 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr4_-_76944621 0.62 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr14_-_24615805 0.62 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr2_-_188419078 0.61 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_+_49977466 0.61 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr7_-_92146729 0.60 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr3_+_113251143 0.60 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chrX_+_23682379 0.60 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr7_-_30066233 0.60 ENST00000222803.5
FKBP14
FK506 binding protein 14, 22 kDa
chr7_-_83824169 0.60 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_68788594 0.59 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chrX_-_20236970 0.59 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr8_+_26150628 0.58 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr10_+_94608245 0.58 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr15_+_78832747 0.58 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr12_+_8850277 0.58 ENST00000539923.1
ENST00000537189.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr6_+_26183958 0.58 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr17_+_57297807 0.57 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr4_-_155511887 0.57 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr22_+_18632666 0.57 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr10_+_22614547 0.56 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr4_-_185395191 0.56 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr11_-_46141338 0.56 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr2_-_216240386 0.56 ENST00000438981.1
FN1
fibronectin 1
chr11_-_57335280 0.56 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr4_+_41614720 0.56 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr7_-_102985288 0.55 ENST00000379263.3
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr22_+_36649056 0.55 ENST00000397278.3
ENST00000422706.1
ENST00000426053.1
ENST00000319136.4
APOL1
apolipoprotein L, 1
chr14_+_24605361 0.54 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr10_+_16478942 0.54 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER
phosphotriesterase related
chr14_-_35099377 0.54 ENST00000362031.4
SNX6
sorting nexin 6
chr12_-_8693469 0.53 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr5_-_133706695 0.53 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr9_+_102668915 0.53 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chrX_-_71525742 0.53 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr1_-_111506562 0.53 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr19_+_10196981 0.52 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr11_+_46402297 0.52 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr17_+_28443799 0.52 ENST00000584423.1
ENST00000247026.5
NSRP1
nuclear speckle splicing regulatory protein 1
chrX_+_102631248 0.52 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_+_82373379 0.52 ENST00000396027.4
ENST00000511817.1
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr12_-_54652060 0.52 ENST00000552562.1
CBX5
chromobox homolog 5
chr12_+_79258547 0.52 ENST00000457153.2
SYT1
synaptotagmin I
chr4_-_187112626 0.52 ENST00000596414.1
AC110771.1
Uncharacterized protein
chr7_-_102985035 0.51 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DNAJC2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr11_+_46402744 0.51 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr4_-_129491686 0.51 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr5_+_34915444 0.51 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr1_-_226496898 0.50 ENST00000481685.1
LIN9
lin-9 homolog (C. elegans)
chr12_-_8693539 0.50 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr9_-_123812542 0.50 ENST00000223642.1
C5
complement component 5
chr1_-_150738261 0.50 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr4_+_95916947 0.50 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_+_101659682 0.49 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr8_+_109455845 0.49 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr17_-_4642429 0.49 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr3_+_141103634 0.49 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_228244013 0.48 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr18_-_71815051 0.48 ENST00000582526.1
ENST00000419743.2
FBXO15
F-box protein 15
chr1_-_111746966 0.48 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr2_+_210444748 0.48 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr1_-_243349684 0.47 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr8_+_90914073 0.47 ENST00000297438.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr4_-_146101304 0.46 ENST00000447906.2
OTUD4
OTU domain containing 4
chr11_+_34654011 0.46 ENST00000531794.1
EHF
ets homologous factor
chr5_+_38845960 0.46 ENST00000502536.1
OSMR
oncostatin M receptor
chr2_+_99771418 0.46 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
LIPT1
MRPL30
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr6_+_125304502 0.46 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
RNF217
ring finger protein 217
chr1_-_114430169 0.45 ENST00000393316.3
BCL2L15
BCL2-like 15
chr8_+_27629459 0.45 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr6_+_87865262 0.45 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr10_+_94590910 0.45 ENST00000371547.4
EXOC6
exocyst complex component 6
chr12_-_12674032 0.45 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr2_+_202122703 0.44 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr20_-_32580924 0.44 ENST00000432859.1
RP5-1125A11.1
RP5-1125A11.1
chr14_+_35747825 0.44 ENST00000540871.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr10_+_22610876 0.44 ENST00000442508.1
BMI1
BMI1 polycomb ring finger oncogene
chr6_+_142468383 0.43 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr2_-_153032484 0.43 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr12_+_8849773 0.43 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr4_-_39034542 0.43 ENST00000344606.6
TMEM156
transmembrane protein 156
chr6_+_142468361 0.43 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr10_-_114206649 0.43 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr8_-_74495065 0.43 ENST00000523533.1
STAU2
staufen double-stranded RNA binding protein 2
chr14_-_35099315 0.42 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 17.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
3.3 9.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.5 6.0 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
1.3 5.3 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.2 14.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.8 4.2 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.8 2.4 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.7 2.1 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.7 7.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.6 3.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5 3.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 4.7 GO:0018377 protein myristoylation(GO:0018377)
0.4 2.1 GO:0030421 defecation(GO:0030421)
0.3 1.6 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.3 0.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 1.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.3 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.2 0.9 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 2.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 1.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 3.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 1.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.6 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.2 0.7 GO:0071283 cellular response to iron(III) ion(GO:0071283)
0.2 0.6 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.7 GO:0043335 protein unfolding(GO:0043335)
0.1 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.8 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.5 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 6.4 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 1.0 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 10.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.6 GO:0018879 biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.9 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.1 0.4 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.3 GO:1903217 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.2 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.6 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.3 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:2000510 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 1.2 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.7 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:0046292 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.1 1.5 GO:0007379 segment specification(GO:0007379)
0.1 0.3 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.3 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) regulation of osteoclast proliferation(GO:0090289)
0.1 0.6 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 2.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.7 GO:0009913 epidermal cell differentiation(GO:0009913) keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.3 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:1902728 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 1.3 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 3.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 2.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 1.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:0048392 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0072716 response to actinomycin D(GO:0072716)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.5 GO:0070673 response to interleukin-18(GO:0070673)
0.0 1.3 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0042462 photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) cellular response to lead ion(GO:0071284) stress response to copper ion(GO:1990169)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:1903764 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.7 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0008537 proteasome activator complex(GO:0008537)
0.3 0.9 GO:0018444 translation release factor complex(GO:0018444)
0.3 1.1 GO:0031213 RSF complex(GO:0031213)
0.2 0.7 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 1.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 15.7 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.1 1.0 GO:0097422 tubular endosome(GO:0097422)
0.1 1.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 2.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.7 GO:0033391 chromatoid body(GO:0033391)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 6.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 2.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 4.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 2.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 10.7 GO:0010008 endosome membrane(GO:0010008)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.5 GO:0035580 specific granule lumen(GO:0035580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.9 11.8 GO:0031386 protein tag(GO:0031386)
0.4 1.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.3 1.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.3 2.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 1.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 9.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.6 GO:0016768 spermine synthase activity(GO:0016768)
0.2 6.8 GO:0005521 lamin binding(GO:0005521)
0.2 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 1.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.5 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 6.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.7 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.9 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.6 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.7 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.0 GO:0050693 LBD domain binding(GO:0050693)
0.1 2.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 10.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.3 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 7.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.8 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 1.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 3.6 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0043394 proteoglycan binding(GO:0043394)
0.0 4.2 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 8.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 3.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 9.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.8 PID ATM PATHWAY ATM pathway
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 73.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 5.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 1.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.8 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation