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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRX5

Z-value: 1.02

Motif logo

Transcription factors associated with IRX5

Gene Symbol Gene ID Gene Info
ENSG00000176842.10 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRX5hg19_v2_chr16_+_54964740_54964789-0.276.0e-01Click!

Activity profile of IRX5 motif

Sorted Z-values of IRX5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_141264597 1.59 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
short coiled-coil protein
chr8_+_84824920 1.05 ENST00000523678.1
RP11-120I21.2
chr12_+_2912363 0.70 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr1_+_196788887 0.63 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr12_+_21679220 0.51 ENST00000256969.2
chromosome 12 open reading frame 39
chr8_-_108510224 0.48 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr7_+_23210760 0.48 ENST00000366347.4
Uncharacterized protein
chr15_+_81225699 0.48 ENST00000560027.1
KIAA1199
chr4_-_104119528 0.47 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr7_-_92777606 0.47 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr11_+_31531291 0.44 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr9_+_26746951 0.43 ENST00000523363.1
RP11-18A15.1
chr3_+_180586536 0.42 ENST00000465551.1
fragile X mental retardation, autosomal homolog 1
chr22_-_24096562 0.42 ENST00000398465.3
pre-B lymphocyte 3
chr14_+_56127960 0.41 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr8_-_74495065 0.40 ENST00000523533.1
staufen double-stranded RNA binding protein 2
chr9_+_42704004 0.39 ENST00000457288.1
COBW domain containing 7
chr8_+_101349823 0.38 ENST00000519566.1
KB-1991G8.1
chr1_-_62190793 0.36 ENST00000371177.2
ENST00000606498.1
TM2 domain containing 1
chr20_+_10199468 0.36 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr10_-_18944123 0.36 ENST00000606425.1
Uncharacterized protein
chr14_+_39944025 0.35 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr14_+_56127989 0.35 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr1_+_63989004 0.34 ENST00000371088.4
EF-hand calcium binding domain 7
chr13_+_97928395 0.34 ENST00000445661.2
muscleblind-like splicing regulator 2
chr12_-_76462713 0.33 ENST00000552056.1
nucleosome assembly protein 1-like 1
chrX_-_15353629 0.30 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
phosphatidylinositol glycan anchor biosynthesis, class A
chr3_+_53528659 0.30 ENST00000350061.5
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr3_+_186158169 0.30 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
chr17_+_38673270 0.29 ENST00000578280.1
RP5-1028K7.2
chr10_+_96698406 0.29 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr7_+_116502527 0.28 ENST00000361183.3
capping protein (actin filament) muscle Z-line, alpha 2
chr1_+_220267429 0.28 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr2_+_191792376 0.28 ENST00000409428.1
ENST00000409215.1
glutaminase
chr8_+_27631903 0.28 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr4_+_75480629 0.28 ENST00000380846.3
amphiregulin B
chr12_-_123728548 0.27 ENST00000545406.1
M-phase phosphoprotein 9
chr3_-_27498235 0.27 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_-_197115818 0.26 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr1_-_89488510 0.26 ENST00000564665.1
ENST00000370481.4
guanylate binding protein 3
chr6_+_12008986 0.26 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chrX_+_108779004 0.26 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr14_+_35747825 0.26 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr3_+_188817891 0.26 ENST00000412373.1
tumor protein p63 regulated 1
chr15_-_63448973 0.26 ENST00000462430.1
ribosomal protein S27-like
chr1_+_97188188 0.26 ENST00000541987.1
polypyrimidine tract binding protein 2
chr6_+_149887377 0.26 ENST00000367419.5
glycoprotein integral membrane 1
chrX_-_19988382 0.25 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr15_-_64665911 0.25 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
Uncharacterized protein
chr19_-_36909528 0.25 ENST00000392161.3
ENST00000392171.1
ZFP82 zinc finger protein
chr12_+_56114151 0.25 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
retinol dehydrogenase 5 (11-cis/9-cis)
chr9_-_19065082 0.24 ENST00000415524.1
HAUS augmin-like complex, subunit 6
chr3_+_111630451 0.24 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr17_-_67264947 0.24 ENST00000586811.1
ATP-binding cassette, sub-family A (ABC1), member 5
chr18_+_22006580 0.24 ENST00000284202.4
impact RWD domain protein
chr2_-_228579305 0.24 ENST00000456524.1
solute carrier family 19 (thiamine transporter), member 3
chr2_+_160590469 0.24 ENST00000409591.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr1_-_85156417 0.23 ENST00000422026.1
synovial sarcoma, X breakpoint 2 interacting protein
chr2_+_58655520 0.23 ENST00000455219.3
ENST00000449448.2
long intergenic non-protein coding RNA 1122
chr7_-_16844611 0.22 ENST00000401412.1
ENST00000419304.2
anterior gradient 2
chr17_+_22022437 0.22 ENST00000540040.1
MT-RNR2-like 1
chr8_-_17555164 0.22 ENST00000297488.6
microtubule associated tumor suppressor 1
chr3_-_81792780 0.22 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr5_+_169011033 0.21 ENST00000513795.1
spindle apparatus coiled-coil protein 1
chr18_+_22006646 0.21 ENST00000585067.1
ENST00000578221.1
impact RWD domain protein
chr13_+_76362974 0.21 ENST00000497947.2
LIM domain 7
chr7_+_77469439 0.21 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr11_-_31014214 0.21 ENST00000406071.2
ENST00000339794.5
doublecortin domain containing 1
chr16_+_19535133 0.21 ENST00000396212.2
ENST00000381396.5
centriolar coiled coil protein 110kDa
chr2_+_38177575 0.20 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr5_+_140566 0.20 ENST00000502646.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr1_+_53480598 0.20 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr18_+_52258390 0.20 ENST00000321600.1
dynactin associated protein
chr4_+_75310851 0.19 ENST00000395748.3
ENST00000264487.2
amphiregulin
chr11_+_114310237 0.19 ENST00000539119.1
RNA exonuclease 2
chr4_+_113558612 0.19 ENST00000505034.1
ENST00000324052.6
La ribonucleoprotein domain family, member 7
chr17_-_7108436 0.19 ENST00000493294.1
discs, large homolog 4 (Drosophila)
chr3_-_149470229 0.18 ENST00000473414.1
COMM domain containing 2
chr17_-_29641104 0.18 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr8_+_67976593 0.18 ENST00000262210.5
ENST00000412460.1
centrosome and spindle pole associated protein 1
chrX_-_83757399 0.18 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
highly divergent homeobox
chr4_+_130017268 0.18 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr5_+_54455946 0.18 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr2_-_32236002 0.18 ENST00000404530.1
mediator of cell motility 1
chr11_+_57531292 0.17 ENST00000524579.1
catenin (cadherin-associated protein), delta 1
chr16_+_48657361 0.17 ENST00000565072.1
RP11-42I10.1
chr2_+_113299990 0.17 ENST00000537335.1
ENST00000417433.2
polymerase (RNA) I polypeptide B, 128kDa
chr3_+_101659682 0.17 ENST00000465215.1
RP11-221J22.1
chr15_-_56757329 0.17 ENST00000260453.3
meiosis-specific nuclear structural 1
chr2_+_102624977 0.17 ENST00000441002.1
interleukin 1 receptor, type II
chr1_-_115124257 0.17 ENST00000369541.3
breast carcinoma amplified sequence 2
chr2_-_238333919 0.16 ENST00000409162.1
Uncharacterized protein
chr11_+_114166536 0.15 ENST00000299964.3
nicotinamide N-methyltransferase
chr3_-_3221358 0.15 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr1_+_212475148 0.15 ENST00000537030.3
protein phosphatase 2, regulatory subunit B', alpha
chr6_+_27925019 0.15 ENST00000244623.1
olfactory receptor, family 2, subfamily B, member 6
chr17_-_18430160 0.15 ENST00000392176.3
family with sequence similarity 106, member A
chr4_+_26344754 0.15 ENST00000515573.1
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_1578674 0.15 ENST00000253934.5
transmembrane protein 204
chr5_-_93447333 0.15 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr1_+_53308398 0.15 ENST00000371528.1
zyg-11 family member A, cell cycle regulator
chr18_+_33709834 0.15 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
elongator acetyltransferase complex subunit 2
chr19_-_52531600 0.15 ENST00000356322.6
ENST00000270649.6
zinc finger protein 614
chr12_-_100486668 0.14 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1 binding protein 1-like
chr12_-_25102252 0.14 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr10_-_35379524 0.14 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
cullin 2
chr12_+_75874460 0.14 ENST00000266659.3
GLI pathogenesis-related 1
chr4_-_104119488 0.14 ENST00000514974.1
centromere protein E, 312kDa
chr12_+_58335360 0.14 ENST00000300145.3
XRCC6 binding protein 1
chr15_+_49170083 0.14 ENST00000530028.2
EP300 interacting inhibitor of differentiation 1
chr16_+_19535235 0.14 ENST00000565376.2
ENST00000396208.2
centriolar coiled coil protein 110kDa
chr18_-_32924372 0.14 ENST00000261332.6
ENST00000399061.3
zinc finger protein 24
chr15_+_21145765 0.13 ENST00000553416.1
cancer/testis antigen 60 (non-protein coding)
chr18_-_44702668 0.13 ENST00000256433.3
immediate early response 3 interacting protein 1
chr20_+_54933971 0.13 ENST00000371384.3
ENST00000437418.1
family with sequence similarity 210, member B
chr9_+_95909309 0.13 ENST00000366188.2
RP11-370F5.4
chr10_+_90660832 0.13 ENST00000371924.1
STAM binding protein-like 1
chr10_-_14050522 0.13 ENST00000342409.2
FERM domain containing 4A
chr11_-_22647350 0.13 ENST00000327470.3
Fanconi anemia, complementation group F
chr6_-_117747015 0.12 ENST00000368508.3
ENST00000368507.3
c-ros oncogene 1 , receptor tyrosine kinase
chr11_+_34999328 0.12 ENST00000526309.1
pyruvate dehydrogenase complex, component X
chr5_+_169010638 0.12 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
spindle apparatus coiled-coil protein 1
chr1_+_87458692 0.12 ENST00000370548.2
ENST00000356813.4
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr14_+_96722539 0.12 ENST00000553356.1
bradykinin receptor B1
chr4_+_41361616 0.12 ENST00000513024.1
LIM and calponin homology domains 1
chr15_+_66585555 0.12 ENST00000319194.5
ENST00000525134.2
ENST00000441424.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr1_-_145826450 0.12 ENST00000462900.2
G protein-coupled receptor 89A
chr12_+_32655048 0.11 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr4_+_80584903 0.11 ENST00000506460.1
RP11-452C8.1
chr2_-_242041607 0.11 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
MTERF domain containing 2
chr14_-_95624227 0.11 ENST00000526495.1
dicer 1, ribonuclease type III
chr13_+_50589390 0.10 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr10_-_115904361 0.10 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr17_+_58018269 0.10 ENST00000591035.1
Uncharacterized protein
chr12_+_56114189 0.10 ENST00000548082.1
retinol dehydrogenase 5 (11-cis/9-cis)
chr7_+_6121296 0.10 ENST00000428901.1
AC004895.4
chr10_-_51958906 0.10 ENST00000489640.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr8_-_101962777 0.10 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr4_-_186392898 0.10 ENST00000510617.1
ENST00000307588.3
coiled-coil domain containing 110
chr5_+_67576109 0.10 ENST00000522084.1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_+_95558771 0.09 ENST00000391679.1
HCG2009141; PRO2397; Uncharacterized protein
chr19_-_44388116 0.09 ENST00000587539.1
zinc finger protein 404
chr19_-_40596828 0.09 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
zinc finger protein 780A
chr4_+_122722466 0.09 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
exosome component 9
chr14_+_51706886 0.09 ENST00000457354.2
thioredoxin-related transmembrane protein 1
chr2_+_210517895 0.08 ENST00000447185.1
microtubule-associated protein 2
chr1_+_158969752 0.08 ENST00000566111.1
interferon, gamma-inducible protein 16
chr7_-_99573640 0.08 ENST00000411734.1
alpha-2-glycoprotein 1, zinc-binding
chr4_-_75695366 0.08 ENST00000512743.1
betacellulin
chr8_+_27947746 0.08 ENST00000521015.1
ENST00000521570.1
elongator acetyltransferase complex subunit 3
chr7_-_112430427 0.08 ENST00000449743.1
ENST00000441474.1
ENST00000454074.1
ENST00000447395.1
transmembrane protein 168
chr11_+_114310102 0.07 ENST00000265881.5
RNA exonuclease 2
chr4_+_123653882 0.07 ENST00000433287.1
Bardet-Biedl syndrome 12
chr15_+_66585879 0.07 ENST00000319212.4
DIS3 mitotic control homolog (S. cerevisiae)-like
chr18_-_46784778 0.07 ENST00000582399.1
dymeclin
chr1_-_114355083 0.07 ENST00000261441.5
round spermatid basic protein 1
chr13_+_96085847 0.07 ENST00000376873.3
claudin 10
chr7_-_99573677 0.07 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr5_+_96079240 0.07 ENST00000515663.1
calpastatin
chr3_-_72897545 0.07 ENST00000325599.8
SHQ1, H/ACA ribonucleoprotein assembly factor
chr13_-_41768654 0.07 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr7_+_13141097 0.07 ENST00000411542.1
AC011288.2
chr1_-_241683001 0.07 ENST00000366560.3
fumarate hydratase
chr8_+_9009202 0.07 ENST00000518496.1
Uncharacterized protein
chr6_-_111804905 0.07 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_+_12809463 0.06 ENST00000380663.3
ENST00000380668.5
ENST00000398491.2
ENST00000489404.1
phosphoribosyl pyrophosphate synthetase 2
chr19_+_20959098 0.06 ENST00000360204.5
ENST00000594534.1
zinc finger protein 66
chr9_-_4666337 0.06 ENST00000381890.5
spermatogenesis associated 6-like
chr8_-_67976509 0.06 ENST00000518747.1
COP9 signalosome subunit 5
chr15_-_81616446 0.06 ENST00000302824.6
StAR-related lipid transfer (START) domain containing 5
chr1_+_240408560 0.06 ENST00000441342.1
ENST00000545751.1
formin 2
chr2_-_32490801 0.06 ENST00000360906.5
ENST00000342905.6
NLR family, CARD domain containing 4
chr15_-_51630772 0.06 ENST00000557858.1
ENST00000558328.1
ENST00000396404.4
ENST00000561075.1
ENST00000405011.2
ENST00000559980.1
ENST00000453807.2
ENST00000396402.1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr4_+_159131630 0.06 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
transmembrane protein 144
chr14_-_68159152 0.06 ENST00000554035.1
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr18_-_28622774 0.06 ENST00000434452.1
desmocollin 3
chr3_-_52713729 0.06 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
polybromo 1
chr9_-_125667618 0.06 ENST00000423239.2
ring finger and CCCH-type domains 2
chr14_-_21737551 0.05 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr12_-_102224704 0.05 ENST00000299314.7
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr6_-_138833630 0.05 ENST00000533765.1
NHS-like 1
chr1_-_227505289 0.05 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr2_-_40657397 0.05 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_111804393 0.05 ENST00000368802.3
ENST00000368805.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr4_-_38784592 0.05 ENST00000502321.1
toll-like receptor 10
chr14_-_106845789 0.05 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr2_-_88125471 0.05 ENST00000398146.3
RANBP2-like and GRIP domain containing 2
chr10_-_31146615 0.05 ENST00000444692.2
zinc finger protein 438
chr4_-_22444733 0.05 ENST00000508133.1
G protein-coupled receptor 125
chr1_-_85870177 0.05 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1
chr12_-_58329819 0.04 ENST00000551421.1
RP11-620J15.3
chr1_-_213020991 0.04 ENST00000332912.3
chromosome 1 open reading frame 227
chr13_-_88323218 0.04 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr20_-_3762087 0.04 ENST00000379756.3
sperm flagellar 1
chr10_-_97175444 0.04 ENST00000486141.2
sorbin and SH3 domain containing 1
chr11_-_6790286 0.03 ENST00000338569.2
olfactory receptor, family 2, subfamily AG, member 2
chr2_-_38056538 0.03 ENST00000413792.1
long intergenic non-protein coding RNA 211
chr5_+_81601166 0.03 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_-_46068969 0.03 ENST00000542109.1
ENST00000395946.2
chemokine (C motif) receptor 1
chr1_-_110284384 0.03 ENST00000540225.1
glutathione S-transferase mu 3 (brain)

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071262 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.4 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 1.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.5 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.2 GO:1903899 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.2 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling