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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF1

Z-value: 1.29

Motif logo

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.4 Kruppel like factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_129980210.483.4e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58145889 1.48 ENST00000547853.1
cyclin-dependent kinase 4
chr2_+_74212073 1.45 ENST00000441217.1
AC073046.25
chr3_+_49449636 0.96 ENST00000273590.3
T-cell leukemia translocation altered
chrX_-_16888276 0.85 ENST00000493145.1
retinoblastoma binding protein 7
chr17_+_7210921 0.80 ENST00000573542.1
eukaryotic translation initiation factor 5A
chr19_-_44008863 0.74 ENST00000601646.1
pleckstrin homology-like domain, family B, member 3
chr1_-_145589424 0.72 ENST00000334513.5
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr10_+_17272608 0.71 ENST00000421459.2
vimentin
chr17_+_7210852 0.70 ENST00000576930.1
eukaryotic translation initiation factor 5A
chr12_-_58212487 0.68 ENST00000549994.1
advillin
chr14_+_21569245 0.68 ENST00000556585.2
transmembrane protein 253
chr3_-_50383096 0.67 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr17_+_46131912 0.65 ENST00000584634.1
ENST00000580050.1
nuclear factor, erythroid 2-like 1
chr15_-_44069513 0.63 ENST00000433927.1
elongation factor RNA polymerase II-like 3
chr20_-_62168672 0.57 ENST00000217185.2
protein tyrosine kinase 6
chrX_+_47077680 0.57 ENST00000522883.1
cyclin-dependent kinase 16
chr8_-_123793048 0.57 ENST00000607710.1
RP11-44N11.2
chr11_+_62475130 0.56 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr2_+_206950095 0.55 ENST00000435627.1
AC007383.3
chr14_-_100841794 0.54 ENST00000556295.1
ENST00000554820.1
tryptophanyl-tRNA synthetase
chr2_-_26205340 0.54 ENST00000264712.3
kinesin family member 3C
chr17_-_7493390 0.52 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chr13_-_74708372 0.52 ENST00000377666.4
Kruppel-like factor 12
chr19_+_54960358 0.51 ENST00000439657.1
ENST00000376514.2
ENST00000376526.4
ENST00000436479.1
leukocyte receptor cluster (LRC) member 8
chr17_+_7210898 0.51 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr8_-_145018080 0.51 ENST00000354589.3
plectin
chr6_-_38607673 0.50 ENST00000481247.1
BTB (POZ) domain containing 9
chrX_+_47077632 0.50 ENST00000457458.2
cyclin-dependent kinase 16
chr20_-_52687030 0.50 ENST00000411563.1
breast carcinoma amplified sequence 1
chr15_+_76352178 0.50 ENST00000388942.3
chromosome 15 open reading frame 27
chr6_-_38607628 0.49 ENST00000498633.1
BTB (POZ) domain containing 9
chr17_-_46716647 0.48 ENST00000608940.1
RP11-357H14.17
chr11_-_1606513 0.47 ENST00000382171.2
keratin associated protein 5-1
chr22_-_20138302 0.47 ENST00000540078.1
ENST00000439765.2
uncharacterized protein LOC388849
chr2_+_75185619 0.45 ENST00000483063.1
polymerase (DNA-directed), epsilon 4, accessory subunit
chr14_-_100841670 0.45 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
tryptophanyl-tRNA synthetase
chr19_+_54960790 0.45 ENST00000443957.1
leukocyte receptor cluster (LRC) member 8
chr5_+_133562095 0.44 ENST00000602919.1
CTD-2410N18.3
chr17_+_7210294 0.44 ENST00000336452.7
eukaryotic translation initiation factor 5A
chr12_+_57943781 0.43 ENST00000455537.2
ENST00000286452.5
kinesin family member 5A
chr2_-_26205550 0.43 ENST00000405914.1
kinesin family member 3C
chr14_+_77425972 0.43 ENST00000553613.1
RP11-7F17.7
chr20_+_825275 0.42 ENST00000541082.1
family with sequence similarity 110, member A
chr16_-_30597000 0.42 ENST00000470110.1
ENST00000395216.2
zinc finger protein 785
chr9_-_33264676 0.42 ENST00000472232.3
ENST00000379704.2
BCL2-associated athanogene
chr17_-_1619535 0.41 ENST00000573075.1
ENST00000574306.1
MIR22 host gene (non-protein coding)
chr1_+_156096336 0.41 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr9_-_33264557 0.41 ENST00000473781.1
ENST00000488499.1
BCL2-associated athanogene
chr17_+_1633755 0.41 ENST00000545662.1
WD repeat domain 81
chr16_+_50313426 0.40 ENST00000569265.1
adenylate cyclase 7
chr11_+_63655987 0.39 ENST00000509502.2
ENST00000512060.1
MAP/microtubule affinity-regulating kinase 2
chr12_-_100378392 0.39 ENST00000549866.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_+_24783906 0.38 ENST00000396782.2
leukotriene B4 receptor
chr17_-_34122596 0.37 ENST00000250144.8
matrix metallopeptidase 28
chr1_+_167190066 0.37 ENST00000367866.2
ENST00000429375.2
ENST00000452019.1
ENST00000420254.3
ENST00000541643.3
POU class 2 homeobox 1
chr16_+_31483451 0.36 ENST00000565360.1
ENST00000361773.3
transforming growth factor beta 1 induced transcript 1
chr15_-_78112553 0.36 ENST00000562933.1
leucine rich repeat and Ig domain containing 1
chr12_-_58131931 0.36 ENST00000547588.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr11_-_65314905 0.35 ENST00000527339.1
latent transforming growth factor beta binding protein 3
chr3_-_105588231 0.35 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr11_+_47608198 0.35 ENST00000356737.2
ENST00000538490.1
family with sequence similarity 180, member B
chr9_+_74764278 0.34 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr8_+_21912328 0.34 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
dematin actin binding protein
chr19_+_38880252 0.34 ENST00000586301.1
sprouty-related, EVH1 domain containing 3
chr16_+_31483374 0.34 ENST00000394863.3
transforming growth factor beta 1 induced transcript 1
chr9_-_130616915 0.33 ENST00000344849.3
endoglin
chr4_-_90756769 0.33 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_36119975 0.33 ENST00000589559.1
ENST00000360475.4
RNA binding motif protein 42
chrX_-_54824673 0.33 ENST00000218436.6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr15_+_75074410 0.33 ENST00000439220.2
c-src tyrosine kinase
chr16_+_30078811 0.33 ENST00000564688.1
aldolase A, fructose-bisphosphate
chr14_+_77228532 0.33 ENST00000167106.4
ENST00000554237.1
vasohibin 1
chr15_+_75074385 0.33 ENST00000220003.9
c-src tyrosine kinase
chr19_+_36120009 0.33 ENST00000589871.1
RNA binding motif protein 42
chr12_+_116997186 0.33 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr2_-_197458271 0.33 ENST00000427457.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_-_86564696 0.32 ENST00000437769.1
receptor accessory protein 1
chr5_+_133859996 0.32 ENST00000512386.1
jade family PHD finger 2
chr8_+_123793633 0.32 ENST00000314393.4
zinc fingers and homeoboxes 2
chr19_+_41698927 0.32 ENST00000310054.4
cytochrome P450, family 2, subfamily S, polypeptide 1
chr17_-_27188984 0.32 ENST00000582320.2
microRNA 451b
chr11_-_119252425 0.32 ENST00000260187.2
ubiquitin specific peptidase 2
chr16_-_4466622 0.31 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr17_-_79520135 0.31 ENST00000541246.1
ENST00000544302.1
chromosome 17 open reading frame 70
chrX_+_140677562 0.31 ENST00000370518.3
SPANX family, member A2
chr10_-_47173994 0.31 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr19_+_35607166 0.31 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD domain containing ion transport regulator 3
chr1_-_24126051 0.31 ENST00000445705.1
UDP-galactose-4-epimerase
chr6_+_31691121 0.31 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
chromosome 6 open reading frame 25
chr1_+_43148059 0.30 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr12_-_56693758 0.30 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
citrate synthase
chr1_+_11866270 0.30 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr19_+_42788172 0.30 ENST00000160740.3
capicua transcriptional repressor
chr19_-_39340563 0.30 ENST00000601813.1
heterogeneous nuclear ribonucleoprotein L
chr3_-_71114066 0.30 ENST00000485326.2
forkhead box P1
chr19_+_39574945 0.30 ENST00000331256.5
Iron/zinc purple acid phosphatase-like protein
chr9_-_130617029 0.30 ENST00000373203.4
endoglin
chr6_-_31763276 0.30 ENST00000440048.1
valyl-tRNA synthetase
chr18_+_29027696 0.30 ENST00000257189.4
desmoglein 3
chr17_+_46125685 0.30 ENST00000579889.1
nuclear factor, erythroid 2-like 1
chr11_-_64014379 0.29 ENST00000309318.3
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr22_+_38071615 0.29 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr6_+_33359582 0.29 ENST00000450504.1
kinesin family member C1
chr7_-_35840198 0.29 ENST00000412856.1
ENST00000437235.3
ENST00000424194.1
AC007551.3
chr12_-_57443886 0.29 ENST00000300119.3
myosin IA
chr15_-_72521017 0.29 ENST00000561609.1
pyruvate kinase, muscle
chr5_-_89770171 0.29 ENST00000514906.1
metallo-beta-lactamase domain containing 2
chr1_+_17914907 0.29 ENST00000375420.3
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_+_219524473 0.28 ENST00000439945.1
ENST00000431802.1
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr17_+_39845134 0.28 ENST00000591776.1
ENST00000469257.1
eukaryotic translation initiation factor 1
chr17_-_27405875 0.28 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr11_+_65339820 0.28 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
family with sequence similarity 89, member B
chr17_-_79519403 0.28 ENST00000327787.8
ENST00000537152.1
chromosome 17 open reading frame 70
chr1_+_33231221 0.28 ENST00000294521.3
KIAA1522
chr17_-_26220366 0.28 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr19_-_47616992 0.28 ENST00000253048.5
zinc finger CCCH-type containing 4
chr11_+_65647280 0.28 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr19_+_1077393 0.28 ENST00000590577.1
histocompatibility (minor) HA-1
chr1_+_11866207 0.27 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr5_+_321810 0.27 ENST00000514523.1
aryl-hydrocarbon receptor repressor
chr19_-_10676666 0.27 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1 homolog (S. cerevisiae)
chr12_-_63544718 0.27 ENST00000299178.2
arginine vasopressin receptor 1A
chr6_-_30654977 0.27 ENST00000399199.3
protein phosphatase 1, regulatory subunit 18
chr1_-_39395165 0.27 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr17_-_74023291 0.27 ENST00000586740.1
envoplakin
chr17_-_74023474 0.27 ENST00000301607.3
envoplakin
chr4_+_39640787 0.27 ENST00000532680.1
RP11-539G18.2
chr15_+_88795953 0.26 ENST00000569588.1
NTRK3 antisense RNA 1
chr13_+_24553933 0.26 ENST00000424834.2
ENST00000439928.2
spermatogenesis associated 13
RP11-309I15.1
chr5_+_71403061 0.26 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr19_+_42806250 0.26 ENST00000598490.1
ENST00000341747.3
proline rich 19
chr19_+_18668572 0.26 ENST00000540691.1
ENST00000539106.1
ENST00000222307.4
KxDL motif containing 1
chr1_+_27189631 0.26 ENST00000339276.4
stratifin
chr16_+_67233007 0.26 ENST00000360833.1
ENST00000393997.2
engulfment and cell motility 3
chr4_-_926161 0.26 ENST00000511163.1
cyclin G associated kinase
chr11_+_1889880 0.26 ENST00000405957.2
lymphocyte-specific protein 1
chr17_-_39538550 0.25 ENST00000394001.1
keratin 34
chr19_+_42363917 0.25 ENST00000598742.1
ribosomal protein S19
chr6_+_106546808 0.25 ENST00000369089.3
PR domain containing 1, with ZNF domain
chr17_+_37030127 0.25 ENST00000419929.1
LIM and SH3 protein 1
chr17_-_2117600 0.25 ENST00000572369.1
SMG6 nonsense mediated mRNA decay factor
chrX_+_47078069 0.25 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
cyclin-dependent kinase 16
chr1_-_24126023 0.25 ENST00000429356.1
UDP-galactose-4-epimerase
chr8_+_145490549 0.25 ENST00000340695.2
scleraxis homolog A (mouse)
chr1_-_94147385 0.24 ENST00000260502.6
breast cancer anti-estrogen resistance 3
chr19_+_41699135 0.24 ENST00000542619.1
ENST00000600561.1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr1_-_159893507 0.24 ENST00000368096.1
transgelin 2
chr9_-_35732362 0.24 ENST00000314888.9
ENST00000540444.1
talin 1
chr17_-_1389228 0.24 ENST00000438665.2
myosin IC
chr6_-_131291572 0.24 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr19_+_18451439 0.24 ENST00000597431.2
pyroglutamyl-peptidase I
chr1_-_161039753 0.23 ENST00000368015.1
Rho GTPase activating protein 30
chr17_-_41174367 0.23 ENST00000587173.1
vesicle amine transport 1
chr22_+_20119320 0.23 ENST00000334554.7
ENST00000320602.7
ENST00000405930.3
zinc finger, DHHC-type containing 8
chr3_-_45838011 0.23 ENST00000358525.4
ENST00000413781.1
solute carrier family 6 (proline IMINO transporter), member 20
chr10_-_94003003 0.23 ENST00000412050.4
cytoplasmic polyadenylation element binding protein 3
chr11_+_65657875 0.23 ENST00000312579.2
coiled-coil domain containing 85B
chr14_+_32414059 0.23 ENST00000553330.1
Uncharacterized protein
chr14_-_21566731 0.22 ENST00000360947.3
zinc finger protein 219
chr11_+_71903169 0.22 ENST00000393676.3
folate receptor 1 (adult)
chr9_-_135819987 0.22 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr17_-_56065540 0.22 ENST00000583932.1
vascular endothelial zinc finger 1
chr1_-_98510843 0.22 ENST00000413670.2
ENST00000538428.1
MIR137 host gene (non-protein coding)
chr19_-_36523529 0.21 ENST00000593074.1
CAP-GLY domain containing linker protein 3
chr2_-_70944855 0.21 ENST00000415348.1
adducin 2 (beta)
chr22_-_36357671 0.21 ENST00000408983.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr17_-_46703826 0.21 ENST00000550387.1
ENST00000311177.5
homeobox B9
chr9_-_140353748 0.21 ENST00000371472.2
ENST00000371475.3
ENST00000265663.7
ENST00000437259.1
ENST00000392812.4
ENST00000371474.3
ENST00000371473.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr19_-_42916499 0.21 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr17_-_40575535 0.21 ENST00000357037.5
polymerase I and transcript release factor
chr7_+_127228399 0.21 ENST00000000233.5
ENST00000415666.1
ADP-ribosylation factor 5
chr5_+_140514782 0.21 ENST00000231134.5
protocadherin beta 5
chr2_-_219524193 0.21 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
zinc finger protein 142
chr2_+_242127924 0.21 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr17_+_46131843 0.21 ENST00000577411.1
nuclear factor, erythroid 2-like 1
chr8_+_22423168 0.21 ENST00000518912.1
ENST00000428103.1
sorbin and SH3 domain containing 3
chr1_+_153747746 0.21 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr1_-_161039647 0.21 ENST00000368013.3
Rho GTPase activating protein 30
chr1_-_117664317 0.21 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
tripartite motif containing 45
chr12_+_26274917 0.21 ENST00000538142.1
sarcospan
chr8_+_21911054 0.21 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr17_+_40996590 0.21 ENST00000253799.3
ENST00000452774.2
amine oxidase, copper containing 2 (retina-specific)
chr17_-_1619568 0.20 ENST00000571595.1
MIR22 host gene (non-protein coding)
chr6_+_42952237 0.20 ENST00000485511.1
ENST00000394110.3
ENST00000472118.1
ENST00000461010.1
protein phosphatase 2, regulatory subunit B', delta
chr1_-_11866034 0.20 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr20_+_35974532 0.20 ENST00000373578.2
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr16_+_30075783 0.20 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr3_-_45837959 0.20 ENST00000353278.4
ENST00000456124.2
solute carrier family 6 (proline IMINO transporter), member 20
chr3_-_105587879 0.20 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chrX_-_48814810 0.20 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTU domain containing 5
chr15_-_89878025 0.20 ENST00000268124.5
ENST00000442287.2
polymerase (DNA directed), gamma
chr5_-_115910630 0.20 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_+_140480083 0.20 ENST00000231130.2
protocadherin beta 3
chr19_-_55791540 0.20 ENST00000433386.2
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_-_55791058 0.20 ENST00000587959.1
ENST00000585927.1
ENST00000587922.1
ENST00000585698.1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr17_-_7991021 0.19 ENST00000319144.4
arachidonate 12-lipoxygenase, 12R type
chrX_+_70503526 0.19 ENST00000413858.1
ENST00000450092.1
non-POU domain containing, octamer-binding
chr6_+_43027595 0.19 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
kinesin light chain 4
chr11_-_119252359 0.19 ENST00000455332.2
ubiquitin specific peptidase 2
chr12_+_57998400 0.19 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.6 GO:0001300 chronological cell aging(GO:0001300)
0.2 1.8 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2 0.5 GO:0048627 myoblast development(GO:0048627)
0.2 1.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.0 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.1 0.4 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.4 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.8 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.6 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.8 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.2 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.3 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of cellular pH reduction(GO:0032849) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:0009093 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1 0.3 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:2000771 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 1.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.3 GO:0003096 renal sodium ion transport(GO:0003096)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.3 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.0 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:0093001 glycolytic process through glucose-1-phosphate(GO:0061622) glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.3 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.6 GO:0072563 endothelial microparticle(GO:0072563)
0.2 2.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.5 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.6 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 2.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.7 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.4 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.2 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 2.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle binding(GO:0034189) very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.6 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.9 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion