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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAX_TFEB

Z-value: 0.75

Motif logo

Transcription factors associated with MAX_TFEB

Gene Symbol Gene ID Gene Info
ENSG00000125952.14 MYC associated factor X
ENSG00000112561.13 transcription factor EB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFEBhg19_v2_chr6_-_41701428_41701578-0.651.6e-01Click!
MAXhg19_v2_chr14_-_65569057_655691190.532.8e-01Click!

Activity profile of MAX_TFEB motif

Sorted Z-values of MAX_TFEB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58145889 5.64 ENST00000547853.1
cyclin-dependent kinase 4
chr4_+_76439095 0.68 ENST00000506261.1
THAP domain containing 6
chr16_+_2570431 0.60 ENST00000563556.1
amidohydrolase domain containing 2
chr17_-_7137582 0.60 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr15_-_83316254 0.55 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr9_-_100684769 0.54 ENST00000455506.1
ENST00000375117.4
chromosome 9 open reading frame 156
chr6_-_44225231 0.54 ENST00000538577.1
ENST00000537814.1
ENST00000393810.1
ENST00000393812.3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chrX_-_102565932 0.54 ENST00000372674.1
ENST00000372677.3
brain expressed X-linked 2
chr18_-_3247084 0.52 ENST00000609924.1
RP13-270P17.3
chr12_-_58146128 0.52 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr17_-_7137857 0.51 ENST00000005340.5
dishevelled segment polarity protein 2
chr19_-_10764509 0.50 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr12_-_58146048 0.47 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr19_+_49458107 0.46 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr6_-_33385870 0.43 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr3_-_178789220 0.43 ENST00000414084.1
zinc finger, matrin-type 3
chr16_+_2570340 0.42 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr12_+_112451222 0.42 ENST00000552052.1
endoplasmic reticulum protein 29
chr9_-_90589586 0.42 ENST00000325303.8
ENST00000375883.3
cyclin-dependent kinase 20
chr17_-_6915616 0.41 ENST00000575889.1
Uncharacterized protein
chr14_-_20929624 0.41 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr12_+_56109926 0.39 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr16_+_2014993 0.39 ENST00000564014.1
small nucleolar RNA host gene 9 (non-protein coding)
chr6_-_33385655 0.38 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr2_+_220042933 0.37 ENST00000430297.2
family with sequence similarity 134, member A
chr1_+_3816936 0.36 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
long intergenic non-protein coding RNA 1134
chr2_+_240323439 0.36 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr18_+_20715416 0.35 ENST00000580153.1
Cdk5 and Abl enzyme substrate 1
chr2_+_232575168 0.35 ENST00000440384.1
prothymosin, alpha
chr2_+_121493717 0.34 ENST00000418323.1
GLI family zinc finger 2
chr15_+_44084040 0.34 ENST00000249786.4
small EDRK-rich factor 2
chr17_-_48450534 0.32 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr1_+_44440575 0.32 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr9_-_90589402 0.32 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
cyclin-dependent kinase 20
chr1_+_43613566 0.31 ENST00000409396.1
family with sequence similarity 183, member A
chr17_+_46970127 0.31 ENST00000355938.5
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr22_+_31003133 0.31 ENST00000405742.3
transcobalamin II
chr9_+_96928516 0.30 ENST00000602703.1
RP11-2B6.3
chr5_+_150827143 0.30 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr6_-_33385823 0.29 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr14_-_20922960 0.29 ENST00000553640.1
ENST00000488532.2
O-sialoglycoprotein endopeptidase
chr3_-_195163584 0.29 ENST00000439666.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr19_-_2096478 0.29 ENST00000591236.1
ENST00000589902.1
MOB kinase activator 3A
chr22_+_31002779 0.29 ENST00000215838.3
transcobalamin II
chrX_-_102565858 0.28 ENST00000449185.1
ENST00000536889.1
brain expressed X-linked 2
chr17_+_46970178 0.28 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr3_+_127317705 0.27 ENST00000480910.1
minichromosome maintenance complex component 2
chr2_+_176981307 0.27 ENST00000249501.4
homeobox D10
chr7_+_72742178 0.27 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr2_-_47572105 0.27 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr10_+_23728198 0.26 ENST00000376495.3
OTU domain containing 1
chr12_-_49463753 0.26 ENST00000301068.6
Ras homolog enriched in brain like 1
chr20_+_44519948 0.26 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr8_-_123793048 0.25 ENST00000607710.1
RP11-44N11.2
chr9_+_92219919 0.25 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr5_+_133706865 0.25 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr17_+_46970134 0.25 ENST00000503641.1
ENST00000514808.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_+_56109810 0.24 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr19_-_36545649 0.24 ENST00000292894.1
THAP domain containing 8
chr11_-_61560053 0.24 ENST00000537328.1
transmembrane protein 258
chr17_-_77967433 0.24 ENST00000571872.1
TBC1 domain family, member 16
chr1_-_241520525 0.23 ENST00000366565.1
regulator of G-protein signaling 7
chr16_+_5083950 0.23 ENST00000588623.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr3_-_20227720 0.23 ENST00000412997.1
shugoshin-like 1 (S. pombe)
chr15_+_44084503 0.23 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr3_+_184530173 0.23 ENST00000453056.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr19_-_10047219 0.23 ENST00000264833.4
olfactomedin 2
chr12_+_54366894 0.23 ENST00000546378.1
ENST00000243082.4
homeobox C11
chr19_-_10426663 0.23 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
ferredoxin 1-like
chr22_-_38577782 0.22 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
phospholipase A2, group VI (cytosolic, calcium-independent)
chr19_-_11688260 0.22 ENST00000590832.1
acid phosphatase 5, tartrate resistant
chr19_+_10765003 0.22 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr12_-_121972556 0.22 ENST00000545022.1
lysine (K)-specific demethylase 2B
chr1_-_154531095 0.22 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr2_-_220042825 0.22 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr5_-_175964366 0.22 ENST00000274811.4
ring finger protein 44
chr11_-_61560254 0.21 ENST00000543510.1
transmembrane protein 258
chr13_+_113951607 0.21 ENST00000397181.3
lysosomal-associated membrane protein 1
chr20_+_44520009 0.21 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr19_+_10764937 0.21 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr11_+_65779283 0.21 ENST00000312134.2
cystatin E/M
chr1_+_43637996 0.21 ENST00000528956.1
ENST00000529956.1
WD repeat domain 65
chr17_-_18266818 0.21 ENST00000583780.1
serine hydroxymethyltransferase 1 (soluble)
chr1_+_152486950 0.21 ENST00000368790.3
cysteine-rich C-terminal 1
chr12_+_56110247 0.21 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr6_-_138866823 0.20 ENST00000342260.5
NHS-like 1
chr7_+_100464760 0.20 ENST00000200457.4
thyroid hormone receptor interactor 6
chr12_+_54426637 0.20 ENST00000312492.2
homeobox C5
chr3_-_45883558 0.20 ENST00000445698.1
ENST00000296135.6
leucine zipper transcription factor-like 1
chr11_+_67159416 0.20 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr14_-_36536396 0.20 ENST00000546376.1
RP11-116N8.4
chr9_-_98268883 0.20 ENST00000551630.1
ENST00000548420.1
patched 1
chr9_+_130860810 0.20 ENST00000433501.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr5_-_110074603 0.20 ENST00000515278.2
transmembrane protein 232
chr11_-_36310958 0.20 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMM domain containing 9
chrX_+_102883620 0.20 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chr16_-_28503327 0.20 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr17_-_48450265 0.20 ENST00000507088.1
mitochondrial ribosomal protein L27
chr7_+_99070527 0.20 ENST00000379724.3
zinc finger protein 789
chrX_+_100878112 0.20 ENST00000491568.2
ENST00000479298.1
armadillo repeat containing, X-linked 3
chr2_+_148778570 0.20 ENST00000407073.1
methyl-CpG binding domain protein 5
chr22_-_20850070 0.19 ENST00000440659.2
ENST00000458248.1
ENST00000443285.1
ENST00000444967.1
ENST00000451553.1
ENST00000431430.1
kelch-like family member 22
chr16_-_4897266 0.19 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
glyoxylate reductase 1 homolog (Arabidopsis)
chr19_+_41256764 0.19 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
small nuclear ribonucleoprotein polypeptide A
chr6_-_163834852 0.19 ENST00000604200.1
colon adenocarcinoma hypermethylated (non-protein coding)
chr15_-_72668805 0.19 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr16_-_1525016 0.19 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chr3_-_196065374 0.19 ENST00000454715.1
transmembrane 4 L six family member 19
chr21_-_46237883 0.19 ENST00000397893.3
small ubiquitin-like modifier 3
chr5_+_149340339 0.19 ENST00000433184.1
solute carrier family 26 (anion exchanger), member 2
chr7_+_30791743 0.19 ENST00000013222.5
ENST00000409539.1
indolethylamine N-methyltransferase
chr1_+_11866207 0.18 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr5_+_176730769 0.18 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr6_-_33385902 0.18 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr16_+_4897632 0.18 ENST00000262376.6
ubinuclein 1
chr11_+_62538775 0.18 ENST00000294168.3
ENST00000526261.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr3_+_51428704 0.18 ENST00000323686.4
RNA binding motif protein 15B
chr7_+_117864708 0.18 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ankyrin repeat domain 7
chr11_+_67776012 0.18 ENST00000539229.1
aldehyde dehydrogenase 3 family, member B1
chr19_-_45681482 0.18 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
trafficking protein particle complex 6A
chr17_-_46688334 0.18 ENST00000239165.7
homeobox B7
chr16_-_2097787 0.18 ENST00000566380.1
ENST00000219066.1
nth endonuclease III-like 1 (E. coli)
chr1_-_8939265 0.18 ENST00000489867.1
enolase 1, (alpha)
chr3_+_19988736 0.18 ENST00000443878.1
RAB5A, member RAS oncogene family
chr10_+_51827648 0.18 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr22_+_31002990 0.17 ENST00000423350.1
transcobalamin II
chr11_-_57283159 0.17 ENST00000533263.1
ENST00000278426.3
solute carrier family 43 (amino acid system L transporter), member 1
chr7_+_75024903 0.17 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr22_-_36903069 0.17 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr9_+_130860583 0.17 ENST00000373064.5
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr17_-_30677020 0.17 ENST00000583774.1
chromosome 17 open reading frame 75
chr3_-_142720267 0.17 ENST00000597953.1
RP11-91G21.1
chr19_-_36545128 0.17 ENST00000538849.1
THAP domain containing 8
chr7_+_116593536 0.17 ENST00000417919.1
suppression of tumorigenicity 7
chr19_-_13227534 0.17 ENST00000588229.1
ENST00000357720.4
tRNA methyltransferase 1 homolog (S. cerevisiae)
chr21_-_38639813 0.17 ENST00000309117.6
ENST00000398998.1
Down syndrome critical region gene 3
chr14_+_77564701 0.17 ENST00000557115.1
CLOCK-interacting pacemaker
chr3_-_53080644 0.17 ENST00000497586.1
Scm-like with four mbt domains 1
chr5_+_139944396 0.16 ENST00000514199.1
solute carrier family 35, member A4
chrX_+_118108571 0.16 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr19_+_45681997 0.16 ENST00000433642.2
biogenesis of lysosomal organelles complex-1, subunit 3
chr19_+_7587491 0.16 ENST00000264079.6
mucolipin 1
chr19_+_7587555 0.16 ENST00000601003.1
mucolipin 1
chr3_-_196987309 0.16 ENST00000453607.1
discs, large homolog 1 (Drosophila)
chr6_-_41888843 0.16 ENST00000434077.1
ENST00000409312.1
mediator complex subunit 20
chr19_+_8386371 0.16 ENST00000600659.2
ribosomal protein S28
chr19_+_12848299 0.16 ENST00000357332.3
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr7_+_99699179 0.16 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr17_-_73851285 0.16 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WW domain binding protein 2
chr16_-_28503080 0.16 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr4_-_100242549 0.16 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chr2_-_25475120 0.16 ENST00000380746.4
ENST00000402667.1
DNA (cytosine-5-)-methyltransferase 3 alpha
chr16_+_2014941 0.16 ENST00000531523.1
small nucleolar RNA host gene 9 (non-protein coding)
chr12_-_121342170 0.16 ENST00000353487.2
signal peptide peptidase like 3
chr16_+_84002234 0.16 ENST00000305202.4
N-terminal EF-hand calcium binding protein 2
chr16_-_58718638 0.16 ENST00000562397.1
ENST00000564010.1
ENST00000570214.1
ENST00000563196.1
solute carrier family 38, member 7
chr3_+_113667354 0.16 ENST00000491556.1
zinc finger, DHHC-type containing 23
chrX_+_146993648 0.15 ENST00000370470.1
fragile X mental retardation 1
chr19_+_40854363 0.15 ENST00000599685.1
ENST00000392032.2
phospholipase D family, member 3
chr17_+_7211656 0.15 ENST00000416016.2
eukaryotic translation initiation factor 5A
chr1_-_205744205 0.15 ENST00000446390.2
RAB7, member RAS oncogene family-like 1
chr9_-_134145880 0.15 ENST00000372269.3
ENST00000464831.1
family with sequence similarity 78, member A
chr17_-_62097927 0.15 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr7_+_94537247 0.15 ENST00000422324.1
protein phosphatase 1, regulatory subunit 9A
chr8_+_22414182 0.15 ENST00000524057.1
sorbin and SH3 domain containing 3
chr20_-_44519839 0.15 ENST00000372518.4
neuralized E3 ubiquitin protein ligase 2
chr2_+_10183651 0.14 ENST00000305883.1
Kruppel-like factor 11
chr12_-_122750957 0.14 ENST00000451053.2
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr2_-_220252530 0.14 ENST00000521459.1
aspartyl aminopeptidase
chr16_-_28503357 0.14 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr15_-_72668185 0.14 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr16_+_1401924 0.14 ENST00000204679.4
ENST00000529110.1
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr17_-_42200996 0.14 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr7_+_99699280 0.14 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr18_+_32556892 0.14 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr14_-_65569057 0.14 ENST00000555419.1
ENST00000341653.2
MYC associated factor X
chr1_+_11333546 0.14 ENST00000376804.2
UbiA prenyltransferase domain containing 1
chr1_-_154909329 0.14 ENST00000368467.3
phosphomevalonate kinase
chr1_+_154909803 0.14 ENST00000604546.1
RP11-307C12.13
chr12_-_114404111 0.14 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RNA binding motif protein 19
chr8_-_144679264 0.14 ENST00000531953.1
ENST00000526133.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr5_-_150138246 0.14 ENST00000518015.1
dynactin 4 (p62)
chr22_-_50699972 0.14 ENST00000395778.3
mitogen-activated protein kinase 12
chr1_-_156265438 0.14 ENST00000362007.1
chromosome 1 open reading frame 85
chr20_-_61051026 0.14 ENST00000252997.2
GATA binding protein 5
chr16_+_89228757 0.14 ENST00000565008.1
long intergenic non-protein coding RNA 304
chr16_+_70207686 0.14 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
C-type lectin domain family 18, member C
chr8_-_128960591 0.14 ENST00000539634.1
transmembrane protein 75
chr19_-_56109119 0.13 ENST00000587678.1
FLT3-interacting zinc finger 1
chr16_+_70613770 0.13 ENST00000429149.2
ENST00000563721.2
interleukin 34
chr8_+_95907993 0.13 ENST00000523378.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr7_+_100271446 0.13 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_26758849 0.13 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
dehydrodolichyl diphosphate synthase
chr17_-_32906388 0.13 ENST00000357754.1
chromosome 17 open reading frame 102
chr19_-_11545920 0.13 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr14_+_20923350 0.13 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr20_-_2821756 0.13 ENST00000356872.3
ENST00000439542.1
PC-esterase domain containing 1A
chr12_+_6644443 0.13 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_111991850 0.13 ENST00000411751.2
WD repeat domain 77
chr8_+_94929273 0.13 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MAX_TFEB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.6 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 1.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.5 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.2 0.5 GO:1902512 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 1.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.4 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.1 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.3 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.3 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.2 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0015808 L-alanine transport(GO:0015808)
0.1 1.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.5 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.2 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0021510 spinal cord development(GO:0021510)
0.0 0.1 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309) L-arginine import(GO:0043091) divalent metal ion export(GO:0070839) arginine import(GO:0090467)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.8 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0019858 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0034709 methylosome(GO:0034709)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 6.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.3 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.8 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.5 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.2 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.4 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.0 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.0 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation