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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MBD2

Z-value: 1.35

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51751132_51751158-0.721.1e-01Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_74212073 3.83 ENST00000441217.1
AC073046.25
AC073046.25
chr17_-_31404 1.09 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr1_+_156698743 1.00 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr8_-_145688231 0.89 ENST00000530374.1
CYHR1
cysteine/histidine-rich 1
chr8_+_61592073 0.88 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr11_+_76092353 0.87 ENST00000530460.1
ENST00000321844.4
RP11-111M22.2
Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.
chr2_+_239756671 0.80 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr2_+_42275153 0.77 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr6_+_41514305 0.77 ENST00000409208.1
ENST00000373057.3
FOXP4
forkhead box P4
chr16_+_2059872 0.75 ENST00000567649.1
NPW
neuropeptide W
chr5_+_14143728 0.73 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr14_-_21566731 0.71 ENST00000360947.3
ZNF219
zinc finger protein 219
chr19_-_14201507 0.70 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr19_-_14201776 0.69 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr17_+_27920486 0.65 ENST00000394859.3
ANKRD13B
ankyrin repeat domain 13B
chr19_-_41222775 0.65 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr5_+_149865838 0.64 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_-_2059748 0.63 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr11_+_118978045 0.62 ENST00000336702.3
C2CD2L
C2CD2-like
chr16_+_2022036 0.61 ENST00000568546.1
TBL3
transducin (beta)-like 3
chr16_-_2059797 0.61 ENST00000563630.1
ZNF598
zinc finger protein 598
chr16_+_57769635 0.61 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr4_-_6474173 0.60 ENST00000382599.4
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr20_+_36531544 0.58 ENST00000448944.1
VSTM2L
V-set and transmembrane domain containing 2 like
chr14_-_74416829 0.56 ENST00000534936.1
FAM161B
family with sequence similarity 161, member B
chr12_+_122516626 0.54 ENST00000319080.7
MLXIP
MLX interacting protein
chr11_-_64684672 0.53 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr19_-_36545649 0.53 ENST00000292894.1
THAP8
THAP domain containing 8
chr1_+_156698708 0.52 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr19_+_36545833 0.52 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr19_+_56152361 0.50 ENST00000585995.1
ENST00000592996.1
ZNF581
CCDC106
zinc finger protein 581
coiled-coil domain containing 106
chr1_+_43148059 0.50 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr19_+_38879061 0.49 ENST00000587013.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr3_+_14989076 0.49 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_+_156698234 0.49 ENST00000368218.4
ENST00000368216.4
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr10_-_79686284 0.48 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr17_+_36861735 0.44 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr20_-_56284816 0.44 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr18_+_19750894 0.44 ENST00000581694.1
GATA6
GATA binding protein 6
chr9_-_130616915 0.44 ENST00000344849.3
ENG
endoglin
chr11_-_47198380 0.42 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr15_-_82338460 0.42 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr2_+_220306238 0.42 ENST00000435853.1
SPEG
SPEG complex locus
chr5_+_176853702 0.42 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr5_+_176853669 0.42 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr11_-_75236867 0.42 ENST00000376282.3
ENST00000336898.3
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr3_+_112930946 0.42 ENST00000462425.1
BOC
BOC cell adhesion associated, oncogene regulated
chr12_-_50222187 0.42 ENST00000335999.6
NCKAP5L
NCK-associated protein 5-like
chr3_+_33155444 0.41 ENST00000320954.6
CRTAP
cartilage associated protein
chr19_+_10527449 0.41 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr8_+_145137489 0.40 ENST00000355091.4
ENST00000525087.1
ENST00000361036.6
ENST00000524418.1
GPAA1
glycosylphosphatidylinositol anchor attachment 1
chr5_-_176778803 0.39 ENST00000303127.7
LMAN2
lectin, mannose-binding 2
chr10_+_115803650 0.39 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr8_+_144349606 0.39 ENST00000521682.1
ENST00000340042.1
GLI4
GLI family zinc finger 4
chr11_-_130786333 0.39 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr14_-_74417096 0.38 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr1_+_156252708 0.38 ENST00000295694.5
ENST00000357501.2
TMEM79
transmembrane protein 79
chr9_-_130617029 0.38 ENST00000373203.4
ENG
endoglin
chr6_-_31763276 0.38 ENST00000440048.1
VARS
valyl-tRNA synthetase
chr20_-_48532046 0.38 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr17_+_64961026 0.38 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr12_+_120972147 0.38 ENST00000325954.4
ENST00000542438.1
RNF10
ring finger protein 10
chr12_+_120972606 0.37 ENST00000413266.2
RNF10
ring finger protein 10
chr10_-_123357910 0.37 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2
fibroblast growth factor receptor 2
chr2_+_11052054 0.37 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr1_+_43855560 0.37 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr15_-_42783303 0.37 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr8_-_141645645 0.37 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr5_-_176778523 0.36 ENST00000513877.1
ENST00000515209.1
ENST00000514458.1
ENST00000502560.1
LMAN2
lectin, mannose-binding 2
chr14_-_77787198 0.36 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr9_-_136933615 0.36 ENST00000371834.2
BRD3
bromodomain containing 3
chr1_-_179851611 0.36 ENST00000610272.1
RP11-533E19.7
RP11-533E19.7
chr16_+_2732476 0.36 ENST00000301738.4
ENST00000564195.1
KCTD5
potassium channel tetramerization domain containing 5
chr15_-_65715401 0.35 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr17_-_80231557 0.35 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr1_-_156252590 0.35 ENST00000361813.5
ENST00000368267.5
SMG5
SMG5 nonsense mediated mRNA decay factor
chr17_-_61920280 0.35 ENST00000448276.2
ENST00000577990.1
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_-_27693349 0.35 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr1_+_110881945 0.34 ENST00000602849.1
ENST00000487146.2
RBM15
RNA binding motif protein 15
chr20_-_48532019 0.34 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr7_-_150864635 0.34 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr9_-_136933092 0.33 ENST00000357885.2
BRD3
bromodomain containing 3
chr22_-_19419205 0.33 ENST00000340170.4
ENST00000263208.5
HIRA
histone cell cycle regulator
chr2_-_46769694 0.33 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr19_-_41196458 0.33 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr19_-_16653226 0.32 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr1_+_46269248 0.32 ENST00000361297.2
ENST00000372009.2
MAST2
microtubule associated serine/threonine kinase 2
chr19_+_38397839 0.32 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr11_-_46615498 0.32 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
AMBRA1
autophagy/beclin-1 regulator 1
chr12_+_6875519 0.32 ENST00000389462.4
ENST00000540874.1
ENST00000309083.6
PTMS
parathymosin
chr14_-_99737822 0.32 ENST00000345514.2
ENST00000443726.2
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr12_+_68042517 0.32 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr17_-_79876010 0.31 ENST00000328666.6
SIRT7
sirtuin 7
chr12_+_7037461 0.31 ENST00000396684.2
ATN1
atrophin 1
chr11_-_67141090 0.31 ENST00000312438.7
CLCF1
cardiotrophin-like cytokine factor 1
chr3_-_183979251 0.31 ENST00000296238.3
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr5_+_170846640 0.31 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr16_+_3019246 0.31 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr2_-_208031542 0.31 ENST00000423015.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_156698591 0.31 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr22_-_20792089 0.31 ENST00000405555.3
ENST00000266214.5
SCARF2
scavenger receptor class F, member 2
chr19_-_41196534 0.31 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr19_-_42759300 0.31 ENST00000222329.4
ERF
Ets2 repressor factor
chr2_+_181845532 0.30 ENST00000602475.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr19_+_56152262 0.30 ENST00000325333.5
ENST00000590190.1
ZNF580
zinc finger protein 580
chr14_-_93581615 0.30 ENST00000555553.1
ENST00000555495.1
ENST00000554999.1
ITPK1
inositol-tetrakisphosphate 1-kinase
chr14_+_102829300 0.30 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr10_-_105615164 0.30 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr14_-_103523745 0.30 ENST00000361246.2
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr1_+_153606532 0.30 ENST00000403433.1
CHTOP
chromatin target of PRMT1
chr14_+_77787227 0.30 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr11_+_65383227 0.30 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr5_+_153570319 0.30 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_+_42388437 0.29 ENST00000378152.4
ENST00000337665.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_+_14544099 0.29 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr11_-_62414070 0.29 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr5_-_156569850 0.29 ENST00000524219.1
HAVCR2
hepatitis A virus cellular receptor 2
chr8_+_37654424 0.29 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr16_-_30905584 0.29 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr6_-_10415218 0.29 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_-_61919812 0.29 ENST00000225742.9
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr17_+_46125685 0.29 ENST00000579889.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr10_+_104404218 0.29 ENST00000302424.7
TRIM8
tripartite motif containing 8
chr19_-_4124079 0.29 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr1_-_153919128 0.29 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr11_-_64851496 0.28 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chr1_-_32229523 0.28 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
BAI2
brain-specific angiogenesis inhibitor 2
chr11_-_67169265 0.28 ENST00000358239.4
ENST00000376745.4
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr5_+_153570285 0.28 ENST00000425427.2
ENST00000297107.6
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_+_36208877 0.28 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B
Histone-lysine N-methyltransferase 2B
chr17_-_66097610 0.28 ENST00000584047.1
ENST00000579629.1
AC145343.2
AC145343.2
chr14_+_21538517 0.28 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr2_+_241375069 0.28 ENST00000264039.2
GPC1
glypican 1
chr16_+_3019552 0.28 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr3_-_53080047 0.27 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr4_+_2061119 0.27 ENST00000423729.2
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr16_+_3019309 0.27 ENST00000576565.1
PAQR4
progestin and adipoQ receptor family member IV
chr5_-_54523143 0.27 ENST00000513312.1
MCIDAS
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr17_-_5372229 0.27 ENST00000433302.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr16_-_51185149 0.27 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr3_+_33155525 0.27 ENST00000449224.1
CRTAP
cartilage associated protein
chr6_-_16761678 0.27 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr11_-_67169253 0.27 ENST00000527663.1
ENST00000312989.7
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr10_-_103880209 0.27 ENST00000425280.1
LDB1
LIM domain binding 1
chr7_+_129710350 0.26 ENST00000335420.5
ENST00000463413.1
KLHDC10
kelch domain containing 10
chr5_+_133861790 0.26 ENST00000395003.1
PHF15
jade family PHD finger 2
chr6_+_41514078 0.26 ENST00000373063.3
ENST00000373060.1
FOXP4
forkhead box P4
chr2_-_119605253 0.26 ENST00000295206.6
EN1
engrailed homeobox 1
chr11_-_6633799 0.26 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr11_+_61735266 0.26 ENST00000601917.1
AP003733.1
Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
chr9_+_124413873 0.26 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr11_-_64545222 0.26 ENST00000433274.2
ENST00000432725.1
SF1
splicing factor 1
chr13_+_98795505 0.26 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_+_71803201 0.26 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr11_+_46354455 0.26 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr1_+_156084461 0.26 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr20_-_1447547 0.26 ENST00000476071.1
NSFL1C
NSFL1 (p97) cofactor (p47)
chr12_-_120554622 0.26 ENST00000229340.5
RAB35
RAB35, member RAS oncogene family
chr16_-_22385901 0.26 ENST00000268383.2
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr9_-_136933134 0.25 ENST00000303407.7
BRD3
bromodomain containing 3
chr19_-_1568057 0.25 ENST00000402693.4
ENST00000388824.6
MEX3D
mex-3 RNA binding family member D
chr6_+_148663729 0.25 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr19_-_16653325 0.25 ENST00000546361.2
CHERP
calcium homeostasis endoplasmic reticulum protein
chr1_+_179851893 0.25 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr9_-_35732362 0.25 ENST00000314888.9
ENST00000540444.1
TLN1
talin 1
chr12_+_57482877 0.25 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_-_219537134 0.25 ENST00000295704.2
RNF25
ring finger protein 25
chr20_-_1447467 0.25 ENST00000353088.2
ENST00000350991.4
NSFL1C
NSFL1 (p97) cofactor (p47)
chr7_+_69064566 0.25 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr1_+_153606513 0.25 ENST00000368694.3
CHTOP
chromatin target of PRMT1
chr1_-_43232649 0.25 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr17_-_27277615 0.25 ENST00000583747.1
ENST00000584236.1
PHF12
PHD finger protein 12
chr20_-_46415297 0.25 ENST00000467815.1
ENST00000359930.4
SULF2
sulfatase 2
chr15_+_40733387 0.25 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr11_-_67271723 0.24 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr12_+_110152033 0.24 ENST00000538780.1
FAM222A
family with sequence similarity 222, member A
chr6_+_1389989 0.24 ENST00000259806.1
FOXF2
forkhead box F2
chr5_+_179159813 0.24 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr5_-_72744336 0.24 ENST00000499003.3
FOXD1
forkhead box D1
chr19_+_36545781 0.24 ENST00000388999.3
WDR62
WD repeat domain 62
chr1_-_156698181 0.24 ENST00000313146.6
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chr16_-_4166186 0.24 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr12_-_120554534 0.24 ENST00000538903.1
ENST00000534951.1
RAB35
RAB35, member RAS oncogene family
chr7_+_69064300 0.24 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr1_-_40237020 0.24 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr1_+_27561007 0.24 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr2_+_242641442 0.24 ENST00000313552.6
ENST00000406941.1
ING5
inhibitor of growth family, member 5
chr11_+_67056755 0.24 ENST00000511455.2
ENST00000308440.6
ANKRD13D
ankyrin repeat domain 13 family, member D
chr14_+_21538429 0.24 ENST00000298694.4
ENST00000555038.1
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr17_+_48133459 0.24 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr11_+_67055986 0.23 ENST00000447274.2
ANKRD13D
ankyrin repeat domain 13 family, member D
chr17_-_48227877 0.23 ENST00000316878.6
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr19_+_18496957 0.23 ENST00000252809.3
GDF15
growth differentiation factor 15
chr1_-_23857698 0.23 ENST00000361729.2
E2F2
E2F transcription factor 2
chr14_+_53019822 0.23 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr6_-_43596899 0.23 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr19_-_4066890 0.23 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_-_19157248 0.23 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr3_+_49591881 0.23 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr13_+_98795434 0.22 ENST00000376586.2
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 0.8 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.2 GO:0060922 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.2 0.7 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.2 0.5 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.2 GO:0060932 bundle of His development(GO:0003166) His-Purkinje system cell differentiation(GO:0060932)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.4 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.5 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.2 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.3 GO:0002519 natural killer cell tolerance induction(GO:0002519) regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.1 0.4 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.5 GO:0021622 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.5 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 2.0 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.2 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.7 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 0.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0019230 proprioception(GO:0019230)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.4 GO:0042335 cuticle development(GO:0042335)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0014040 acetaldehyde metabolic process(GO:0006117) positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.2 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.6 GO:0006477 protein sulfation(GO:0006477)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.3 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0009093 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0061184 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.3 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.3 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621) attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.2 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.5 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.8 GO:0007099 centriole replication(GO:0007099)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.6 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.4 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0060684 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.6 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 0.8 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 2.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.8 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.5 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway