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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MEF2B

Z-value: 0.43

Motif logo

Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
ENSG00000213999.11 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19281054_192810980.882.2e-02Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_107282368 0.28 ENST00000521369.2
RP11-395G23.3
chr3_-_188665428 0.24 ENST00000444488.1
TPRG1 antisense RNA 1
chr22_-_30642728 0.21 ENST00000403987.3
leukemia inhibitory factor
chr12_+_54384370 0.19 ENST00000504315.1
homeobox C6
chr22_+_19706958 0.18 ENST00000395109.2
septin 5
chr10_-_3827371 0.15 ENST00000469435.1
Kruppel-like factor 6
chr1_-_23751189 0.15 ENST00000374601.3
ENST00000450454.2
transcription elongation factor A (SII), 3
chr12_-_371994 0.15 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr3_+_138067314 0.15 ENST00000423968.2
muscle RAS oncogene homolog
chr22_-_51017084 0.15 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr22_-_51016846 0.14 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr1_+_156095951 0.14 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr12_+_52430894 0.13 ENST00000546842.1
nuclear receptor subfamily 4, group A, member 1
chr19_-_16008880 0.13 ENST00000011989.7
ENST00000221700.6
cytochrome P450, family 4, subfamily F, polypeptide 2
chr14_-_21493649 0.13 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr9_+_97766409 0.13 ENST00000425634.2
chromosome 9 open reading frame 3
chr19_-_49926698 0.13 ENST00000270631.1
parathyroid hormone 2
chr2_-_190044480 0.13 ENST00000374866.3
collagen, type V, alpha 2
chr14_-_21493884 0.13 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG family member 2
chr3_+_138067666 0.13 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr2_-_145188137 0.13 ENST00000440875.1
zinc finger E-box binding homeobox 2
chr2_-_86564696 0.12 ENST00000437769.1
receptor accessory protein 1
chr5_-_150521192 0.11 ENST00000523714.1
ENST00000521749.1
annexin A6
chr7_+_133615169 0.11 ENST00000541309.1
exocyst complex component 4
chr18_+_12407895 0.11 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
slowmo homolog 1 (Drosophila)
chr1_-_156460391 0.11 ENST00000360595.3
myocyte enhancer factor 2D
chr9_-_85882145 0.11 ENST00000328788.1
FERM domain containing 3
chr1_+_22778337 0.10 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr12_-_49393092 0.10 ENST00000421952.2
dendrin
chr14_-_102704783 0.10 ENST00000522534.1
MOK protein kinase
chr22_-_30642782 0.10 ENST00000249075.3
leukemia inhibitory factor
chr16_-_56223480 0.10 ENST00000565155.1
RP11-461O7.1
chr16_+_50313426 0.09 ENST00000569265.1
adenylate cyclase 7
chr2_+_233497931 0.09 ENST00000264059.3
EF-hand domain family, member D1
chr17_-_42188598 0.09 ENST00000591714.1
histone deacetylase 5
chrX_-_131353461 0.09 ENST00000370874.1
RAP2C, member of RAS oncogene family
chr2_-_208031542 0.09 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr12_-_120189900 0.09 ENST00000546026.1
citron (rho-interacting, serine/threonine kinase 21)
chrX_-_15332665 0.09 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr1_+_212782012 0.09 ENST00000341491.4
ENST00000366985.1
activating transcription factor 3
chr9_+_97766469 0.08 ENST00000433691.2
chromosome 9 open reading frame 3
chr19_+_16607122 0.08 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
chromosome 19 open reading frame 44
chr17_-_1389228 0.08 ENST00000438665.2
myosin IC
chr3_-_137834436 0.08 ENST00000327532.2
ENST00000467030.1
DAZ interacting zinc finger protein 1-like
chr1_-_59249732 0.08 ENST00000371222.2
jun proto-oncogene
chr11_+_71934962 0.08 ENST00000543234.1
inositol polyphosphate phosphatase-like 1
chr1_+_74701062 0.08 ENST00000326637.3
TNNI3 interacting kinase
chr17_-_42200958 0.08 ENST00000336057.5
histone deacetylase 5
chr1_-_19229014 0.08 ENST00000538839.1
ENST00000290597.5
aldehyde dehydrogenase 4 family, member A1
chr10_+_102758105 0.08 ENST00000429732.1
leucine zipper, putative tumor suppressor 2
chr14_-_21493123 0.08 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr17_-_1389419 0.07 ENST00000575158.1
myosin IC
chr1_+_156096336 0.07 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr3_-_48598547 0.07 ENST00000536104.1
ENST00000452531.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr14_-_22005343 0.07 ENST00000327430.3
spalt-like transcription factor 2
chr17_-_34417479 0.07 ENST00000225245.5
chemokine (C-C motif) ligand 3
chr6_+_42984723 0.07 ENST00000332245.8
kelch domain containing 3
chr9_+_116327326 0.07 ENST00000342620.5
regulator of G-protein signaling 3
chr20_+_10199566 0.06 ENST00000430336.1
synaptosomal-associated protein, 25kDa
chr2_-_220117867 0.06 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr8_+_1993152 0.06 ENST00000262113.4
myomesin 2
chr11_+_47293795 0.06 ENST00000422579.1
MAP-kinase activating death domain
chr9_-_102582155 0.06 ENST00000427039.1
RP11-554F20.1
chr7_+_75931861 0.06 ENST00000248553.6
heat shock 27kDa protein 1
chr7_+_18536090 0.06 ENST00000441986.1
histone deacetylase 9
chr6_-_169654139 0.06 ENST00000366787.3
thrombospondin 2
chr21_-_33984456 0.06 ENST00000431216.1
ENST00000553001.1
ENST00000440966.1
Uncharacterized protein
chromosome 21 open reading frame 59
chr1_+_77333117 0.06 ENST00000477717.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr5_-_42812143 0.06 ENST00000514985.1
selenoprotein P, plasma, 1
chr1_-_204329013 0.06 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr4_+_41362615 0.05 ENST00000509638.1
LIM and calponin homology domains 1
chr19_-_40324767 0.05 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr3_+_8543533 0.05 ENST00000454244.1
LIM and cysteine-rich domains 1
chr1_+_84630367 0.05 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_49057876 0.05 ENST00000326912.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr17_-_42200996 0.05 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr9_-_16728161 0.05 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr2_+_33661382 0.05 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_-_67867749 0.05 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chr11_-_47374246 0.05 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
myosin binding protein C, cardiac
chr12_+_15699286 0.05 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
protein tyrosine phosphatase, receptor type, O
chr7_-_55583740 0.05 ENST00000453256.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr4_+_160203650 0.05 ENST00000514565.1
Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_7597639 0.04 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_-_52486841 0.04 ENST00000496590.1
troponin C type 1 (slow)
chr17_+_80186908 0.04 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_-_72268889 0.04 ENST00000388742.4
eyes absent homolog 1 (Drosophila)
chr10_-_96829246 0.04 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr3_+_8543561 0.04 ENST00000397386.3
LIM and cysteine-rich domains 1
chr17_-_48785216 0.04 ENST00000285243.6
ankyrin repeat domain 40
chr10_-_3827417 0.04 ENST00000497571.1
ENST00000542957.1
Kruppel-like factor 6
chr11_+_7598239 0.04 ENST00000525597.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_1993173 0.04 ENST00000523438.1
myomesin 2
chr6_-_137314371 0.04 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5
chr14_-_70546897 0.04 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
solute carrier family 8 (sodium/calcium exchanger), member 3
chr12_+_25205568 0.04 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr22_+_32340447 0.03 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr6_+_152128371 0.03 ENST00000443427.1
estrogen receptor 1
chr20_+_32581525 0.03 ENST00000246194.3
ENST00000413297.1
RALY heterogeneous nuclear ribonucleoprotein
chrX_+_70521584 0.03 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr8_-_62602327 0.03 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr12_-_111358372 0.03 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr6_+_44194762 0.03 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_+_52445191 0.03 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4, group A, member 1
chr3_+_188664988 0.03 ENST00000433971.1
tumor protein p63 regulated 1
chrX_-_142722897 0.03 ENST00000338017.4
SLIT and NTRK-like family, member 4
chr22_+_32340481 0.03 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr12_+_25205446 0.03 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr11_-_18034701 0.03 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr3_+_138067521 0.03 ENST00000494949.1
muscle RAS oncogene homolog
chr10_-_97200772 0.03 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr6_-_33160231 0.03 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr3_-_176914191 0.03 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
transducin (beta)-like 1 X-linked receptor 1
chr20_-_62582475 0.03 ENST00000369908.5
uridine-cytidine kinase 1-like 1
chr14_-_103989033 0.03 ENST00000553878.1
ENST00000557530.1
creatine kinase, brain
chr3_+_54157480 0.03 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr10_+_118349920 0.02 ENST00000531984.1
pancreatic lipase-related protein 1
chr20_+_32581738 0.02 ENST00000333552.5
RALY heterogeneous nuclear ribonucleoprotein
chr7_-_37488547 0.02 ENST00000453399.1
engulfment and cell motility 1
chr2_-_157198860 0.02 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr4_+_41362796 0.02 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr15_+_68346501 0.02 ENST00000249636.6
protein inhibitor of activated STAT, 1
chr11_-_88796803 0.02 ENST00000418177.2
ENST00000455756.2
glutamate receptor, metabotropic 5
chr5_-_42811986 0.02 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr9_-_74980113 0.02 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
zinc finger, AN1-type domain 5
chr3_+_35683651 0.02 ENST00000187397.4
cAMP-regulated phosphoprotein, 21kDa
chr12_+_25205666 0.02 ENST00000547044.1
lymphoid-restricted membrane protein
chr14_+_76776957 0.02 ENST00000512784.1
estrogen-related receptor beta
chr1_-_206945830 0.02 ENST00000423557.1
interleukin 10
chr3_+_8543393 0.02 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr1_+_145524891 0.02 ENST00000369304.3
integrin, alpha 10
chr10_-_75415825 0.02 ENST00000394810.2
synaptopodin 2-like
chr10_+_71561630 0.02 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr7_-_15726296 0.02 ENST00000262041.5
mesenchyme homeobox 2
chr12_+_52431016 0.02 ENST00000553200.1
nuclear receptor subfamily 4, group A, member 1
chr10_-_31146615 0.02 ENST00000444692.2
zinc finger protein 438
chr16_-_88717482 0.01 ENST00000261623.3
cytochrome b-245, alpha polypeptide
chr8_+_11351494 0.01 ENST00000259089.4
B lymphoid tyrosine kinase
chr19_-_40324255 0.01 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr14_+_101359265 0.01 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr3_+_127634312 0.01 ENST00000407609.3
kelch repeat and BTB (POZ) domain containing 12
chr20_+_44657845 0.01 ENST00000243964.3
solute carrier family 12 (potassium/chloride transporter), member 5
chr7_-_37488834 0.01 ENST00000310758.4
engulfment and cell motility 1
chr20_+_61147651 0.01 ENST00000370527.3
ENST00000370524.2
chromosome 20 open reading frame 166
chr8_+_11351876 0.01 ENST00000529894.1
B lymphoid tyrosine kinase
chr15_+_42651691 0.01 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
calpain 3, (p94)
chr7_+_18535893 0.01 ENST00000432645.2
ENST00000441542.2
histone deacetylase 9
chr9_-_23779367 0.00 ENST00000440102.1
ELAV like neuron-specific RNA binding protein 2
chr11_+_1860832 0.00 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr7_-_37488777 0.00 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chr8_-_72268968 0.00 ENST00000388740.3
eyes absent homolog 1 (Drosophila)
chr3_+_127634069 0.00 ENST00000405109.1
kelch repeat and BTB (POZ) domain containing 12
chr20_+_44657807 0.00 ENST00000372315.1
solute carrier family 12 (potassium/chloride transporter), member 5
chr8_-_72268721 0.00 ENST00000419131.1
ENST00000388743.2
eyes absent homolog 1 (Drosophila)
chr15_+_40226304 0.00 ENST00000559624.1
ENST00000382727.2
ENST00000263791.5
ENST00000560648.1
eukaryotic translation initiation factor 2 alpha kinase 4
chr10_+_71561704 0.00 ENST00000520267.1
collagen, type XIII, alpha 1
chrX_-_63450480 0.00 ENST00000362002.2
ankyrin repeat and SOCS box containing 12
chr12_-_131200810 0.00 ENST00000536002.1
ENST00000544034.1
RIMS binding protein 2
RP11-662M24.2
chrX_-_11284095 0.00 ENST00000303025.6
ENST00000534860.1
Rho GTPase activating protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.0 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)