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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC1

Z-value: 1.00

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155856_77155939-0.768.1e-02Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_94590910 1.07 ENST00000371547.4
EXOC6
exocyst complex component 6
chr1_+_948803 1.05 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr12_-_92536433 0.96 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr15_-_35280426 0.72 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr15_+_38964048 0.70 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
RP11-275I4.2
chrX_-_84634737 0.65 ENST00000262753.4
POF1B
premature ovarian failure, 1B
chr1_+_79115503 0.62 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr5_+_49962495 0.60 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr14_+_32476072 0.58 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr14_-_92413727 0.58 ENST00000267620.10
FBLN5
fibulin 5
chr2_+_46926326 0.56 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr14_-_92413353 0.53 ENST00000556154.1
FBLN5
fibulin 5
chr11_+_34642656 0.52 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr10_+_22610124 0.47 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr2_+_33701707 0.45 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr21_-_16374688 0.45 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr2_-_42160486 0.44 ENST00000427054.1
AC104654.2
AC104654.2
chr2_+_46926048 0.44 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr3_+_88188254 0.43 ENST00000309495.5
ZNF654
zinc finger protein 654
chr1_+_87595433 0.42 ENST00000469312.2
ENST00000490006.2
RP5-1052I5.1
long intergenic non-protein coding RNA 1140
chr5_-_41510725 0.41 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_+_20968608 0.41 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr4_+_86748898 0.41 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_178976996 0.41 ENST00000485523.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr1_+_150254936 0.41 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr9_-_19065082 0.40 ENST00000415524.1
HAUS6
HAUS augmin-like complex, subunit 6
chr6_+_135818979 0.39 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271
long intergenic non-protein coding RNA 271
chr16_+_53412368 0.38 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr1_-_186649543 0.37 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chrX_-_84634708 0.36 ENST00000373145.3
POF1B
premature ovarian failure, 1B
chr11_-_110167331 0.36 ENST00000534683.1
RDX
radixin
chr2_+_33701684 0.35 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_-_49975632 0.35 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr2_+_201390843 0.34 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chr13_+_37581115 0.34 ENST00000481013.1
EXOSC8
exosome component 8
chr5_+_118690466 0.33 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr9_+_22646189 0.33 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr14_-_35591433 0.33 ENST00000261475.5
ENST00000555644.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_-_13529594 0.32 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr11_-_110167352 0.32 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr3_+_152017360 0.31 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr7_-_87505658 0.31 ENST00000341119.5
SLC25A40
solute carrier family 25, member 40
chr5_-_78808617 0.31 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr14_+_32547434 0.31 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr15_-_30686052 0.30 ENST00000562729.1
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr5_-_39203093 0.30 ENST00000515010.1
FYB
FYN binding protein
chr2_-_228244013 0.30 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr5_+_118691008 0.30 ENST00000504642.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr13_-_108867101 0.30 ENST00000356922.4
LIG4
ligase IV, DNA, ATP-dependent
chr13_+_96085847 0.30 ENST00000376873.3
CLDN10
claudin 10
chr10_+_43932553 0.29 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
ZNF487
zinc finger protein 487
chr11_+_130542851 0.29 ENST00000317019.2
C11orf44
chromosome 11 open reading frame 44
chr1_+_92632542 0.29 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr11_+_11863500 0.29 ENST00000527733.1
ENST00000539466.1
USP47
ubiquitin specific peptidase 47
chr17_+_79495397 0.29 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr1_+_167298281 0.29 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr11_+_36616044 0.29 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr7_-_127032114 0.29 ENST00000436992.1
ZNF800
zinc finger protein 800
chr3_+_69134124 0.28 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_235491714 0.28 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
GGPS1
geranylgeranyl diphosphate synthase 1
chr11_+_11863579 0.28 ENST00000399455.2
USP47
ubiquitin specific peptidase 47
chr21_-_35899113 0.26 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr20_+_36149602 0.26 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr14_+_23025534 0.26 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr5_-_41510656 0.26 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_+_26111823 0.26 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_-_179914760 0.26 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr19_+_35939154 0.26 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr1_-_94703118 0.25 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr13_-_67804445 0.25 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9
protocadherin 9
chr8_+_86121448 0.25 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr7_-_151217166 0.25 ENST00000496004.1
RHEB
Ras homolog enriched in brain
chr14_+_90864504 0.25 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr14_-_35591156 0.24 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr4_+_86749045 0.24 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr7_-_103848405 0.24 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
ORC5
origin recognition complex, subunit 5
chr1_-_153517473 0.24 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr12_+_52431016 0.24 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr5_+_32788945 0.24 ENST00000326958.1
AC026703.1
AC026703.1
chr15_-_59981479 0.24 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr5_+_41904431 0.24 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr7_-_83824449 0.23 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_+_61575200 0.23 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_+_69201923 0.23 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr8_+_38831683 0.23 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr10_-_65028817 0.22 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr12_-_90103077 0.22 ENST00000551310.1
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr7_-_105319536 0.22 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr15_+_23255242 0.22 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr14_+_58894706 0.22 ENST00000261244.5
KIAA0586
KIAA0586
chrX_+_102611373 0.22 ENST00000372661.3
ENST00000372656.3
WBP5
WW domain binding protein 5
chr18_+_77155942 0.21 ENST00000397790.2
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_-_172087824 0.21 ENST00000521943.1
TLK1
tousled-like kinase 1
chr19_-_44388116 0.21 ENST00000587539.1
ZNF404
zinc finger protein 404
chr4_-_38806404 0.21 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr3_+_107364769 0.21 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr1_-_50889155 0.21 ENST00000404795.3
DMRTA2
DMRT-like family A2
chr19_+_10197463 0.21 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr8_+_92082424 0.20 ENST00000285420.4
ENST00000404789.3
OTUD6B
OTU domain containing 6B
chr9_-_20621834 0.20 ENST00000429426.2
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_+_33441053 0.20 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chrX_-_119763835 0.20 ENST00000371313.2
ENST00000304661.5
C1GALT1C1
C1GALT1-specific chaperone 1
chr4_-_71532668 0.20 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_-_65028938 0.20 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr12_-_16760021 0.20 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_95449155 0.19 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr7_-_6010263 0.19 ENST00000455618.2
ENST00000405415.1
ENST00000404406.1
ENST00000542644.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr3_+_184530173 0.19 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_77685084 0.19 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr21_-_35340759 0.19 ENST00000607953.1
AP000569.9
AP000569.9
chr3_-_158390282 0.19 ENST00000264265.3
LXN
latexin
chr14_+_51026926 0.19 ENST00000557735.1
ATL1
atlastin GTPase 1
chr15_-_35261996 0.19 ENST00000156471.5
AQR
aquarius intron-binding spliceosomal factor
chr11_-_102401469 0.18 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr1_-_111743285 0.18 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr3_+_133293278 0.18 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3
CDV3 homolog (mouse)
chr5_+_7869217 0.18 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr3_+_107364683 0.18 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr2_-_68479614 0.18 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr8_-_17555164 0.18 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr4_+_39046615 0.18 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr7_-_100493744 0.18 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr17_+_27047570 0.18 ENST00000472628.1
ENST00000578181.1
RPL23A
ribosomal protein L23a
chr1_+_186649754 0.18 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr3_+_148447887 0.17 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr1_+_218519577 0.17 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chr14_+_35591509 0.17 ENST00000604073.1
KIAA0391
KIAA0391
chr4_-_164534657 0.17 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr4_-_153274078 0.17 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_33440802 0.17 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr16_+_68573116 0.16 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90
ZFP90 zinc finger protein
chr5_+_75904950 0.16 ENST00000502745.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr5_+_135496675 0.16 ENST00000507637.1
SMAD5
SMAD family member 5
chr14_+_35591020 0.16 ENST00000603611.1
KIAA0391
KIAA0391
chr11_-_13461790 0.16 ENST00000530907.1
BTBD10
BTB (POZ) domain containing 10
chr2_+_86668464 0.16 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr3_+_130648842 0.16 ENST00000508297.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr12_+_104359641 0.16 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr1_-_85462762 0.16 ENST00000284027.5
MCOLN2
mucolipin 2
chr15_+_63354769 0.16 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr2_-_40679148 0.16 ENST00000417271.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr11_-_122929699 0.15 ENST00000526686.1
HSPA8
heat shock 70kDa protein 8
chr8_-_102987548 0.15 ENST00000520690.1
NCALD
neurocalcin delta
chr3_+_141596371 0.15 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr4_-_168155300 0.15 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_+_22351977 0.15 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr19_-_30199516 0.15 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr6_-_56716686 0.15 ENST00000520645.1
DST
dystonin
chr17_+_49337881 0.15 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr8_+_57124245 0.15 ENST00000521831.1
ENST00000355315.3
ENST00000303759.3
ENST00000517636.1
ENST00000517933.1
ENST00000518801.1
ENST00000523975.1
ENST00000396723.5
ENST00000523061.1
ENST00000521524.1
CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_+_178866199 0.15 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr1_-_85462623 0.15 ENST00000370608.3
MCOLN2
mucolipin 2
chr17_+_47287749 0.15 ENST00000419580.2
ABI3
ABI family, member 3
chr1_+_82266053 0.14 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr3_+_157261116 0.14 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
C3orf55
chromosome 3 open reading frame 55
chr6_+_22221010 0.14 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr16_-_85969774 0.14 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr1_+_61548225 0.14 ENST00000371187.3
NFIA
nuclear factor I/A
chr3_+_69134080 0.14 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr4_-_104020968 0.14 ENST00000504285.1
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr12_-_56352368 0.14 ENST00000549404.1
PMEL
premelanosome protein
chr12_+_104359614 0.14 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr7_+_107220422 0.14 ENST00000005259.4
BCAP29
B-cell receptor-associated protein 29
chr5_-_7869108 0.14 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FASTKD3
FAST kinase domains 3
chr3_-_27498235 0.14 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr14_+_81421921 0.14 ENST00000554263.1
ENST00000554435.1
TSHR
thyroid stimulating hormone receptor
chr11_+_18417813 0.14 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr12_-_7245018 0.14 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr2_-_230786032 0.14 ENST00000428959.1
TRIP12
thyroid hormone receptor interactor 12
chrX_-_48827976 0.14 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_103574024 0.14 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1
collagen, type XI, alpha 1
chr14_+_51026844 0.14 ENST00000554886.1
ATL1
atlastin GTPase 1
chr11_-_122930121 0.14 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr11_+_392587 0.14 ENST00000534401.1
PKP3
plakophilin 3
chr1_-_91487013 0.13 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr12_+_131356582 0.13 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN
RAN, member RAS oncogene family
chr17_-_46692457 0.13 ENST00000468443.1
HOXB8
homeobox B8
chr16_-_66952742 0.13 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr6_-_130536774 0.13 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr1_+_203734296 0.13 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr8_+_81397846 0.13 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr14_+_51026743 0.13 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1
atlastin GTPase 1
chr6_-_134495992 0.13 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr9_+_123906331 0.13 ENST00000431571.1
CNTRL
centriolin
chr12_+_34175398 0.12 ENST00000538927.1
ALG10
ALG10, alpha-1,2-glucosyltransferase
chr10_-_63995871 0.12 ENST00000315289.2
RTKN2
rhotekin 2
chr9_-_20622478 0.12 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_-_64029879 0.12 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr17_+_27046988 0.12 ENST00000496182.1
RPL23A
ribosomal protein L23a
chr4_-_155471528 0.12 ENST00000302078.5
ENST00000499023.2
PLRG1
pleiotropic regulator 1
chr12_-_123756781 0.12 ENST00000544658.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr4_+_154387480 0.12 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr13_+_49822041 0.12 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr16_-_66952779 0.12 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr17_-_49021974 0.12 ENST00000501718.2
RP11-700H6.1
RP11-700H6.1
chr9_-_16253112 0.12 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr1_-_151798546 0.12 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr3_-_136471204 0.11 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1
stromal antigen 1
chr21_+_35445811 0.11 ENST00000399312.2
MRPS6
mitochondrial ribosomal protein S6
chr10_-_27149904 0.11 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
ABI1
abl-interactor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.4 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.7 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 1.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.4 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 1.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.3 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.2 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.6 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.8 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0038194 thyroid-stimulating hormone signaling pathway(GO:0038194)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0046292 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353) homocysteine catabolic process(GO:0043418)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0048936 visceral motor neuron differentiation(GO:0021524) sensory system development(GO:0048880) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0051286 cell tip(GO:0051286)
0.1 0.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.0 GO:0031386 protein tag(GO:0031386)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1