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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFIA

Z-value: 0.84

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Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
NFIA
ENSG00000162599.11 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61547405_615475340.945.2e-03Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_77582905 1.17 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr1_+_95975672 0.67 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr11_-_104480019 0.62 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr14_-_98444386 0.61 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr1_-_114429997 0.56 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr17_+_14277419 0.55 ENST00000436469.1
AC022816.2
AC022816.2
chr4_+_146402346 0.37 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr16_+_22524379 0.36 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr3_+_69812877 0.36 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr3_-_52002403 0.35 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr19_+_42254885 0.34 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr10_-_99030395 0.34 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr2_+_135596180 0.32 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr7_-_8302298 0.32 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr3_-_131736593 0.31 ENST00000514999.1
CPNE4
copine IV
chr10_+_5238793 0.30 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr6_-_56492816 0.29 ENST00000522360.1
DST
dystonin
chr10_-_6104253 0.29 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr17_-_74533734 0.29 ENST00000589342.1
CYGB
cytoglobin
chr16_+_21312170 0.28 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr6_-_30043539 0.27 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr17_+_19314505 0.27 ENST00000461366.1
RNF112
ring finger protein 112
chr1_-_114430169 0.27 ENST00000393316.3
BCL2L15
BCL2-like 15
chr3_-_33260283 0.25 ENST00000412539.1
SUSD5
sushi domain containing 5
chr8_-_121824374 0.25 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr11_-_93271058 0.25 ENST00000527149.1
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr7_-_41742697 0.24 ENST00000242208.4
INHBA
inhibin, beta A
chr7_-_27135591 0.23 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr2_-_65659762 0.23 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr7_-_56160625 0.22 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr1_+_41447609 0.22 ENST00000543104.1
CTPS1
CTP synthase 1
chr2_+_159651821 0.22 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr11_+_28724129 0.22 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr11_-_111649015 0.22 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr2_-_31637560 0.22 ENST00000379416.3
XDH
xanthine dehydrogenase
chr2_-_158345462 0.21 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chrX_-_131353461 0.21 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chrX_+_122993544 0.21 ENST00000422098.1
XIAP
X-linked inhibitor of apoptosis
chr21_+_35553045 0.21 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr4_-_176733897 0.21 ENST00000393658.2
GPM6A
glycoprotein M6A
chr1_-_205912577 0.20 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr4_-_157892055 0.20 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr12_-_82752159 0.20 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr11_+_126262027 0.20 ENST00000526311.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr17_-_39538550 0.20 ENST00000394001.1
KRT34
keratin 34
chr11_+_64004888 0.20 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr16_-_19725899 0.19 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr9_+_35806082 0.19 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr13_-_46742630 0.19 ENST00000416500.1
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_95510743 0.18 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr11_-_61101247 0.18 ENST00000543627.1
DDB1
damage-specific DNA binding protein 1, 127kDa
chr4_+_156824840 0.18 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr3_-_25824353 0.18 ENST00000427041.1
NGLY1
N-glycanase 1
chr16_+_14802801 0.18 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr6_-_32784687 0.18 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr6_+_106959718 0.17 ENST00000369066.3
AIM1
absent in melanoma 1
chr6_+_108977520 0.17 ENST00000540898.1
FOXO3
forkhead box O3
chr11_+_111385497 0.17 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88
chromosome 11 open reading frame 88
chr9_-_127710292 0.17 ENST00000421514.1
GOLGA1
golgin A1
chr2_-_231989808 0.17 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_122931881 0.17 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chr2_+_33701707 0.17 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_-_19626351 0.16 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr6_+_26156551 0.16 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr3_+_69812701 0.16 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr5_-_168006324 0.16 ENST00000522176.1
PANK3
pantothenate kinase 3
chr12_+_52203789 0.16 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr3_+_190105909 0.16 ENST00000456423.1
CLDN16
claudin 16
chr22_+_37959647 0.16 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr12_+_100897130 0.15 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr20_+_42574317 0.15 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr8_+_124194752 0.15 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr6_+_126221034 0.15 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr15_-_79576156 0.15 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr1_+_150980889 0.15 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE
prune exopolyphosphatase
chr3_-_105588231 0.15 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chrX_+_122993657 0.15 ENST00000434753.3
ENST00000430625.1
XIAP
X-linked inhibitor of apoptosis
chr14_-_54418598 0.15 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr17_+_9745786 0.15 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr7_-_27183263 0.15 ENST00000222726.3
HOXA5
homeobox A5
chr16_+_22518495 0.14 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr5_-_142784101 0.14 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_234590556 0.14 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr1_+_153746683 0.14 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr8_+_66619277 0.14 ENST00000521247.2
ENST00000527155.1
MTFR1
mitochondrial fission regulator 1
chrX_+_135251835 0.14 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr19_-_40724246 0.14 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr4_+_144354644 0.14 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr20_-_14318248 0.14 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr16_-_10652993 0.14 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr8_+_40010989 0.14 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr10_+_95848824 0.14 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr3_+_142342240 0.14 ENST00000497199.1
PLS1
plastin 1
chr9_+_130911770 0.13 ENST00000372998.1
LCN2
lipocalin 2
chrX_+_135252050 0.13 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr9_+_130911723 0.13 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr11_-_10822029 0.13 ENST00000528839.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr5_+_40909354 0.13 ENST00000313164.9
C7
complement component 7
chr3_+_111260980 0.13 ENST00000438817.2
CD96
CD96 molecule
chr3_+_186501979 0.13 ENST00000498746.1
EIF4A2
eukaryotic translation initiation factor 4A2
chr12_+_7169887 0.13 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr22_-_38539487 0.13 ENST00000498338.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr13_-_46716969 0.13 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_67840986 0.13 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1
translin-associated factor X interacting protein 1
chr3_-_176914238 0.13 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr19_-_12997995 0.13 ENST00000264834.4
KLF1
Kruppel-like factor 1 (erythroid)
chr3_+_109128961 0.13 ENST00000489670.1
RP11-702L6.4
RP11-702L6.4
chr5_+_112074029 0.12 ENST00000512211.2
APC
adenomatous polyposis coli
chr16_-_79634595 0.12 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr19_+_36249057 0.12 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr2_-_99485825 0.12 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr22_-_23922410 0.12 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr5_-_142784888 0.12 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_159766528 0.12 ENST00000505287.2
CCNJL
cyclin J-like
chr15_+_59499031 0.12 ENST00000307144.4
LDHAL6B
lactate dehydrogenase A-like 6B
chr8_+_9009296 0.12 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr16_-_15474904 0.12 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr1_+_173684047 0.12 ENST00000546011.1
ENST00000209884.4
KLHL20
kelch-like family member 20
chr8_-_16859690 0.12 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr3_-_176914191 0.12 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr13_+_100634004 0.12 ENST00000376335.3
ZIC2
Zic family member 2
chr8_+_1919481 0.12 ENST00000518539.2
KBTBD11-OT1
KBTBD11 overlapping transcript 1 (non-protein coding)
chr6_+_99282570 0.12 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chrX_-_106146547 0.12 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr5_+_89770696 0.12 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr14_+_70234642 0.11 ENST00000555349.1
ENST00000554021.1
SRSF5
serine/arginine-rich splicing factor 5
chr5_-_142783694 0.11 ENST00000394466.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_+_8995832 0.11 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr9_+_123906331 0.11 ENST00000431571.1
CNTRL
centriolin
chr17_+_1733251 0.11 ENST00000570451.1
RPA1
replication protein A1, 70kDa
chr4_-_48271802 0.11 ENST00000381501.3
TEC
tec protein tyrosine kinase
chr2_-_136288740 0.11 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr8_-_22089533 0.11 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_-_40739501 0.11 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_+_121578211 0.11 ENST00000369080.3
INPP5F
inositol polyphosphate-5-phosphatase F
chr6_+_90192974 0.11 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr12_-_125002827 0.11 ENST00000420698.1
NCOR2
nuclear receptor corepressor 2
chr11_-_85430088 0.11 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr16_-_89119355 0.11 ENST00000537498.1
CTD-2555A7.2
CTD-2555A7.2
chr5_+_148737562 0.11 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr2_-_191878162 0.11 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr17_+_27369918 0.11 ENST00000323372.4
PIPOX
pipecolic acid oxidase
chr8_+_9183618 0.11 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr3_-_121740969 0.11 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chrX_-_13835147 0.10 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr3_-_171177852 0.10 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr2_-_191878681 0.10 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_66797687 0.10 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_200320768 0.10 ENST00000428695.1
SATB2
SATB homeobox 2
chr3_+_69928256 0.10 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr15_-_52030293 0.10 ENST00000560491.1
ENST00000267838.3
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr17_-_74533963 0.10 ENST00000293230.5
CYGB
cytoglobin
chr11_+_118230287 0.10 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr12_+_19389814 0.10 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr18_+_29171689 0.10 ENST00000237014.3
TTR
transthyretin
chr10_+_22614547 0.10 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr13_+_97874574 0.10 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr14_-_64194745 0.10 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr5_-_55777586 0.10 ENST00000506836.1
CTC-236F12.4
Uncharacterized protein
chr2_-_74730087 0.10 ENST00000341396.2
LBX2
ladybird homeobox 2
chr1_+_11839874 0.10 ENST00000449278.1
C1orf167
chromosome 1 open reading frame 167
chr12_-_21910775 0.09 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr1_-_235098935 0.09 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr7_-_24957699 0.09 ENST00000441059.1
ENST00000415162.1
OSBPL3
oxysterol binding protein-like 3
chr3_+_121613265 0.09 ENST00000295605.2
SLC15A2
solute carrier family 15 (oligopeptide transporter), member 2
chr11_+_62556596 0.09 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr12_-_11150474 0.09 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr3_+_4535155 0.09 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr5_-_43313269 0.09 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_+_7462031 0.09 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr4_+_146402997 0.09 ENST00000512019.1
SMAD1
SMAD family member 1
chr3_+_4535025 0.09 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_-_61348292 0.09 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7
synaptotagmin VII
chr8_+_9953214 0.09 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr19_+_13988061 0.09 ENST00000339133.5
ENST00000397555.2
NANOS3
nanos homolog 3 (Drosophila)
chr19_-_40324255 0.09 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr5_+_150157860 0.09 ENST00000600109.1
AC010441.1
AC010441.1
chr3_+_150264555 0.09 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr17_-_62308087 0.09 ENST00000583097.1
TEX2
testis expressed 2
chr11_-_113577052 0.09 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr1_-_155224699 0.09 ENST00000491082.1
FAM189B
family with sequence similarity 189, member B
chr2_+_62132781 0.09 ENST00000311832.5
COMMD1
copper metabolism (Murr1) domain containing 1
chr19_+_17865011 0.09 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr17_+_67957848 0.08 ENST00000455460.1
AC004562.1
AC004562.1
chr2_+_173955327 0.08 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr3_+_150264458 0.08 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr11_-_122930121 0.08 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr17_-_40169161 0.08 ENST00000589586.2
ENST00000426588.3
ENST00000589576.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr5_+_43602750 0.08 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr1_+_209878182 0.08 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr14_-_75330537 0.08 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr11_-_123185475 0.08 ENST00000527774.1
ENST00000527533.1
RP11-109E10.1
RP11-109E10.1
chr1_+_61547405 0.08 ENST00000371189.4
NFIA
nuclear factor I/A
chr19_-_10446449 0.08 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr12_+_56114151 0.08 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_-_59383617 0.08 ENST00000263847.1
OSBP
oxysterol binding protein
chr2_-_211036051 0.08 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr10_-_75193308 0.08 ENST00000299432.2
MSS51
MSS51 mitochondrial translational activator
chr16_-_67185117 0.08 ENST00000449549.3
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr9_-_32635667 0.08 ENST00000242310.4
TAF1L
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.2 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:2000005 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0046449 creatinine metabolic process(GO:0046449)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.3 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.3 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 1.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.0 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism