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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX3-2

Z-value: 1.10

Motif logo

Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_135466740.197.2e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_235098935 0.78 ENST00000423175.1
RP11-443B7.1
chr9_-_32526299 0.60 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr9_-_32526184 0.60 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_+_156824840 0.59 ENST00000536354.2
tryptophan 2,3-dioxygenase
chr4_+_17579110 0.57 ENST00000606142.1
leucine aminopeptidase 3
chr4_-_141348763 0.52 ENST00000509477.1
calmegin
chr17_+_4835580 0.51 ENST00000329125.5
glycoprotein Ib (platelet), alpha polypeptide
chr17_+_38083977 0.46 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr12_-_68845417 0.46 ENST00000542875.1
RP11-81H14.2
chr7_-_56160625 0.45 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
phosphorylase kinase, gamma 1 (muscle)
chrX_+_38420623 0.44 ENST00000378482.2
tetraspanin 7
chr1_+_35734616 0.44 ENST00000441447.1
zinc finger, MYM-type 4
chr3_-_146262293 0.44 ENST00000448205.1
phospholipid scramblase 1
chr19_-_6720686 0.43 ENST00000245907.6
complement component 3
chr3_-_146262428 0.40 ENST00000486631.1
phospholipid scramblase 1
chr6_+_26156551 0.39 ENST00000304218.3
histone cluster 1, H1e
chr4_+_148402069 0.39 ENST00000358556.4
ENST00000339690.5
ENST00000511804.1
ENST00000324300.5
endothelin receptor type A
chr2_+_149402009 0.38 ENST00000457184.1
enhancer of polycomb homolog 2 (Drosophila)
chr16_-_3350614 0.38 ENST00000268674.2
tigger transposable element derived 7
chr19_+_843314 0.38 ENST00000544537.2
proteinase 3
chr19_-_10628098 0.38 ENST00000590601.1
sphingosine-1-phosphate receptor 5
chr1_+_93544821 0.38 ENST00000370303.4
metal response element binding transcription factor 2
chr3_-_146262488 0.38 ENST00000487389.1
phospholipid scramblase 1
chr3_-_149688502 0.36 ENST00000481767.1
ENST00000475518.1
profilin 2
chr5_+_68711209 0.36 ENST00000512803.1
MARVEL domain containing 2
chr9_-_80645520 0.36 ENST00000411677.1
guanine nucleotide binding protein (G protein), q polypeptide
chr6_-_33663474 0.36 ENST00000594414.1
SBP1; Uncharacterized protein
chr7_-_1595756 0.35 ENST00000441933.1
transmembrane protein 184A
chr8_+_86376081 0.34 ENST00000285379.5
carbonic anhydrase II
chr10_-_95360983 0.34 ENST00000371464.3
retinol binding protein 4, plasma
chr14_-_62162541 0.34 ENST00000557544.1
HIF1A antisense RNA 1
chr11_+_34642656 0.33 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr8_-_29592736 0.32 ENST00000518623.1
long intergenic non-protein coding RNA 589
chr9_+_131452239 0.32 ENST00000372688.4
ENST00000372686.5
SET nuclear oncogene
chr7_-_117512264 0.32 ENST00000454375.1
cortactin binding protein 2
chr11_-_77531752 0.32 ENST00000440064.2
ENST00000528095.1
remodeling and spacing factor 1
chr7_+_99971129 0.32 ENST00000394000.2
ENST00000350573.2
paired immunoglobin-like type 2 receptor alpha
chr4_-_141348789 0.32 ENST00000414773.1
calmegin
chr3_-_69249863 0.32 ENST00000478263.1
ENST00000462512.1
FERM domain containing 4B
chr2_+_102927962 0.31 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr20_+_52824367 0.31 ENST00000371419.2
prefoldin subunit 4
chr2_+_220379052 0.31 ENST00000347842.3
ENST00000358078.4
acid-sensing (proton-gated) ion channel family member 4
chr19_-_46526304 0.30 ENST00000008938.4
peptidoglycan recognition protein 1
chr3_+_23847432 0.30 ENST00000346855.3
ubiquitin-conjugating enzyme E2E 1
chr19_-_2282167 0.29 ENST00000342063.3
chromosome 19 open reading frame 35
chr3_-_49907323 0.29 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CaM kinase-like vesicle-associated
chr9_+_35906176 0.29 ENST00000354323.2
histidine rich carboxyl terminus 1
chr3_-_42003613 0.28 ENST00000414606.1
unc-51 like kinase 4
chr11_-_74408739 0.28 ENST00000529912.1
chordin-like 2
chr6_+_24775641 0.27 ENST00000378054.2
ENST00000476555.1
geminin, DNA replication inhibitor
chr11_+_35222629 0.27 ENST00000526553.1
CD44 molecule (Indian blood group)
chr11_+_76813886 0.27 ENST00000529803.1
olfactory marker protein
chr5_-_77072085 0.26 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
tubulin folding cofactor A
chr3_-_130746462 0.26 ENST00000505545.1
asteroid homolog 1 (Drosophila)
chr1_+_173793641 0.26 ENST00000361951.4
aspartyl-tRNA synthetase 2, mitochondrial
chr8_-_82644562 0.25 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
zinc finger, AN1-type domain 1
chr7_+_120629653 0.25 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr1_+_93544791 0.25 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
metal response element binding transcription factor 2
chr2_+_208104497 0.25 ENST00000430494.1
AC007879.7
chr7_-_45957011 0.25 ENST00000417621.1
insulin-like growth factor binding protein 3
chr1_+_151739131 0.25 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr10_+_35416090 0.25 ENST00000354759.3
cAMP responsive element modulator
chr8_+_35649365 0.24 ENST00000437887.1
Uncharacterized protein
chr9_-_124976185 0.24 ENST00000464484.2
LIM homeobox 6
chr7_-_45956856 0.23 ENST00000428530.1
insulin-like growth factor binding protein 3
chr3_+_50192457 0.23 ENST00000414301.1
ENST00000450338.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_38969150 0.23 ENST00000418457.2
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr9_+_34458771 0.23 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr14_+_31494841 0.23 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
adaptor-related protein complex 4, sigma 1 subunit
chr5_-_127418573 0.22 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
chr10_+_35416223 0.22 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr21_-_16437126 0.22 ENST00000318948.4
nuclear receptor interacting protein 1
chr14_-_98444386 0.22 ENST00000556462.1
ENST00000556138.1
chromosome 14 open reading frame 64
chr10_+_16478942 0.22 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
phosphotriesterase related
chr2_-_136288740 0.22 ENST00000264159.6
ENST00000536680.1
zinc finger, RAN-binding domain containing 3
chr4_-_141348999 0.22 ENST00000325617.5
calmegin
chr11_+_77532233 0.22 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr1_+_31769836 0.21 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
zinc finger, CCHC domain containing 17
chr12_+_14518598 0.21 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chr1_+_155911480 0.21 ENST00000368318.3
relaxin/insulin-like family peptide receptor 4
chrX_+_48660565 0.21 ENST00000413163.2
ENST00000441703.1
ENST00000426196.1
histone deacetylase 6
chr6_-_30080863 0.21 ENST00000540829.1
tripartite motif containing 31
chr5_+_75904918 0.21 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQ motif containing GTPase activating protein 2
chr10_+_7745232 0.21 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_233385173 0.21 ENST00000449534.2
protease, serine, 56
chr1_+_173793777 0.21 ENST00000239457.5
aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_222886526 0.21 ENST00000541237.1
axin interactor, dorsalization associated
chr6_-_150039170 0.20 ENST00000458696.2
ENST00000392273.3
large tumor suppressor kinase 1
chr2_+_44396000 0.20 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr8_+_22019168 0.20 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
surfactant protein C
chr6_-_30080876 0.20 ENST00000376734.3
tripartite motif containing 31
chrX_-_15683147 0.20 ENST00000380342.3
transmembrane protein 27
chr14_-_68066849 0.20 ENST00000558493.1
ENST00000561272.1
phosphatidylinositol glycan anchor biosynthesis, class H
chr10_-_104953009 0.20 ENST00000470299.1
ENST00000343289.5
5'-nucleotidase, cytosolic II
chr16_+_89238149 0.20 ENST00000289746.2
cadherin 15, type 1, M-cadherin (myotubule)
chrX_-_119445306 0.20 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
transmembrane protein 255A
chr14_-_35344093 0.19 ENST00000382422.2
bromodomain adjacent to zinc finger domain, 1A
chr5_+_75904950 0.19 ENST00000502745.1
IQ motif containing GTPase activating protein 2
chr10_-_27529779 0.19 ENST00000426079.1
acyl-CoA binding domain containing 5
chr7_-_99573677 0.19 ENST00000292401.4
alpha-2-glycoprotein 1, zinc-binding
chr11_-_64512469 0.19 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr6_+_125304502 0.19 ENST00000519799.1
ENST00000368414.2
ENST00000359704.2
ring finger protein 217
chr3_-_185216766 0.19 ENST00000296254.3
transmembrane protein 41A
chrX_-_131352152 0.19 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr2_+_160568978 0.19 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr3_+_177545563 0.18 ENST00000434309.1
RP11-91K9.1
chr21_-_16437255 0.18 ENST00000400199.1
ENST00000400202.1
nuclear receptor interacting protein 1
chr5_+_34915444 0.18 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr4_-_11430221 0.18 ENST00000514690.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_-_7708918 0.18 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr3_-_107777208 0.17 ENST00000398258.3
CD47 molecule
chr6_+_56820152 0.17 ENST00000370745.1
BEN domain containing 6
chr5_+_118406796 0.17 ENST00000503802.1
Dmx-like 1
chr12_+_50794730 0.17 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
La ribonucleoprotein domain family, member 4
chr1_+_60280458 0.17 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr19_-_56048456 0.17 ENST00000413299.1
SH3 domain binding kinase family, member 2
chr1_+_149230680 0.17 ENST00000443018.1
RP11-403I13.5
chr8_+_42396274 0.16 ENST00000438528.3
small integral membrane protein 19
chr3_+_50192499 0.16 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr21_+_30671690 0.16 ENST00000399921.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr9_-_124976154 0.16 ENST00000482062.1
LIM homeobox 6
chr5_+_118604385 0.16 ENST00000274456.6
tumor necrosis factor, alpha-induced protein 8
chr14_-_50778931 0.16 ENST00000555423.1
ENST00000421284.3
L-2-hydroxyglutarate dehydrogenase
chr12_+_50794891 0.16 ENST00000517559.1
La ribonucleoprotein domain family, member 4
chr5_+_64859066 0.16 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
peptidylprolyl isomerase domain and WD repeat containing 1
chr10_+_96305535 0.16 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
helicase, lymphoid-specific
chr17_+_76126842 0.16 ENST00000590426.1
ENST00000590799.1
ENST00000318430.5
ENST00000589691.1
transmembrane channel-like 8
chr2_+_29336855 0.15 ENST00000404424.1
CAP-GLY domain containing linker protein family, member 4
chr12_-_21928515 0.15 ENST00000537950.1
potassium inwardly-rectifying channel, subfamily J, member 8
chr9_-_139268068 0.15 ENST00000371734.3
ENST00000371732.5
ENST00000315908.7
caspase recruitment domain family, member 9
chr2_+_232572361 0.15 ENST00000409321.1
prothymosin, alpha
chr14_+_35591735 0.15 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
chr19_-_18548921 0.15 ENST00000545187.1
ENST00000578352.1
inositol-3-phosphate synthase 1
chr5_+_179135246 0.15 ENST00000508787.1
calnexin
chr6_-_75994536 0.15 ENST00000475111.2
ENST00000230461.6
transmembrane protein 30A
chr17_+_48823975 0.15 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr12_-_122711968 0.14 ENST00000485724.1
diablo, IAP-binding mitochondrial protein
chr10_+_7745303 0.14 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_160117035 0.14 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr10_-_17171785 0.14 ENST00000377823.1
cubilin (intrinsic factor-cobalamin receptor)
chr14_+_58894404 0.14 ENST00000554463.1
ENST00000555833.1
KIAA0586
chr10_+_70715884 0.14 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr16_+_57406368 0.14 ENST00000006053.6
ENST00000563383.1
chemokine (C-X3-C motif) ligand 1
chr3_-_149688896 0.14 ENST00000239940.7
profilin 2
chr16_-_46723066 0.14 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr11_-_93474645 0.14 ENST00000532455.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr1_+_6845497 0.14 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr20_-_34330129 0.14 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr20_-_49547731 0.14 ENST00000396029.3
activity-dependent neuroprotector homeobox
chr9_+_36572851 0.14 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chrX_-_119695279 0.13 ENST00000336592.6
cullin 4B
chr8_-_123706338 0.13 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr1_+_66258846 0.13 ENST00000341517.4
phosphodiesterase 4B, cAMP-specific
chr1_+_205473784 0.13 ENST00000478560.1
ENST00000443813.2
cyclin-dependent kinase 18
chr7_-_102789503 0.13 ENST00000465647.1
ENST00000418294.1
N-acyl phosphatidylethanolamine phospholipase D
chr15_-_56035177 0.13 ENST00000389286.4
ENST00000561292.1
protogenin
chr17_-_79623597 0.13 ENST00000574024.1
ENST00000331056.5
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr5_+_118604439 0.13 ENST00000388882.5
tumor necrosis factor, alpha-induced protein 8
chr4_+_109571800 0.13 ENST00000512478.2
oligosaccharyltransferase complex subunit (non-catalytic)
chr20_-_49547910 0.13 ENST00000396032.3
activity-dependent neuroprotector homeobox
chr4_+_144258288 0.13 ENST00000514639.1
GRB2-associated binding protein 1
chr18_+_19668021 0.13 ENST00000579830.1
Uncharacterized protein
chr2_-_27294500 0.13 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr1_+_161195835 0.13 ENST00000545897.1
translocase of outer mitochondrial membrane 40 homolog (yeast)-like
chr2_-_24270217 0.13 ENST00000295148.4
ENST00000406895.3
chromosome 2 open reading frame 44
chr5_-_36152031 0.13 ENST00000296603.4
LMBR1 domain containing 2
chr7_+_129015671 0.13 ENST00000466993.1
adenosylhomocysteinase-like 2
chr5_+_112074029 0.13 ENST00000512211.2
adenomatous polyposis coli
chr17_+_68071389 0.13 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_-_160116995 0.13 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr4_-_48018680 0.13 ENST00000513178.1
cyclic nucleotide gated channel alpha 1
chr4_+_26324474 0.13 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr3_+_50192537 0.12 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_35497506 0.12 ENST00000317538.5
ENST00000373340.2
ENST00000357182.4
zinc finger, MYM-type 6
chr1_-_155145721 0.12 ENST00000295682.4
keratinocyte associated protein 2
chrX_-_69269788 0.12 ENST00000276101.3
acyl-CoA wax alcohol acyltransferase 2
chr8_-_144654918 0.12 ENST00000529971.1
maestro heat-like repeat family member 6
chr4_-_4228616 0.12 ENST00000296358.4
otopetrin 1
chr4_-_159080806 0.12 ENST00000590648.1
family with sequence similarity 198, member B
chr15_+_84841242 0.12 ENST00000558195.1
ubiquitin-conjugating enzyme E2Q family member 2-like
chr15_-_63450192 0.12 ENST00000411926.1
ribosomal protein S27-like
chr3_+_184056614 0.12 ENST00000453072.1
family with sequence similarity 131, member A
chr2_+_173940163 0.12 ENST00000539448.1
Mitogen-activated protein kinase kinase kinase MLT
chr12_+_56473939 0.12 ENST00000450146.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chrX_+_106045891 0.12 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr1_-_42801540 0.11 ENST00000372573.1
forkhead box J3
chr6_+_159084188 0.11 ENST00000367081.3
synaptotagmin-like 3
chr11_+_66045634 0.11 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr8_-_27469383 0.11 ENST00000519742.1
clusterin
chr3_-_160117301 0.11 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_+_64879317 0.11 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
transmembrane 7 superfamily member 2
chr1_+_35734562 0.11 ENST00000314607.6
ENST00000373297.2
zinc finger, MYM-type 4
chr3_+_69134080 0.11 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr15_+_78384901 0.11 ENST00000328828.5
SH2 domain containing 7
chr2_-_188312971 0.11 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
calcitonin receptor-like
chr11_-_22851367 0.11 ENST00000354193.4
small VCP/p97-interacting protein
chr12_-_21927736 0.11 ENST00000240662.2
potassium inwardly-rectifying channel, subfamily J, member 8
chr4_+_144303093 0.11 ENST00000505913.1
GRB2-associated binding protein 1
chr12_-_44200146 0.11 ENST00000395510.2
ENST00000325127.4
twinfilin actin-binding protein 1
chr14_-_80782219 0.11 ENST00000553594.1
deiodinase, iodothyronine, type II

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.4 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.1 GO:0048565 digestive tract development(GO:0048565)
0.1 0.3 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 1.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.4 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.5 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:1904936 cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1903998 response to isolation stress(GO:0035900) regulation of eating behavior(GO:1903998)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.0 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.2 GO:0008623 CHRAC(GO:0008623)
0.1 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.2 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC