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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR2E3

Z-value: 1.06

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Transcription factors associated with NR2E3

Gene Symbol Gene ID Gene Info
ENSG00000031544.10 nuclear receptor subfamily 2 group E member 3

Activity profile of NR2E3 motif

Sorted Z-values of NR2E3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_66317967 0.73 ENST00000601398.1
Uncharacterized protein
chr18_-_33047039 0.67 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
chr3_-_186262166 0.59 ENST00000307944.5
crystallin, gamma S
chr13_+_51913819 0.54 ENST00000419898.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr12_-_111142729 0.52 ENST00000546713.1
hydrogen voltage-gated channel 1
chr3_+_69915363 0.48 ENST00000451708.1
microphthalmia-associated transcription factor
chr3_-_195310802 0.45 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr11_+_115498761 0.44 ENST00000424313.2
AP000997.1
chr3_+_141105235 0.42 ENST00000503809.1
zinc finger and BTB domain containing 38
chr16_+_67918708 0.41 ENST00000339176.3
ENST00000576758.1
neuritin 1-like
chr16_-_75569068 0.40 ENST00000336257.3
ENST00000565039.1
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr3_-_185826718 0.39 ENST00000413301.1
ENST00000421809.1
ets variant 5
chrX_-_27417088 0.37 ENST00000608735.1
ENST00000422048.1
RP11-268G12.1
chr14_+_54976603 0.36 ENST00000557317.1
cell growth regulator with ring finger domain 1
chr6_+_148593425 0.35 ENST00000367469.1
SAM and SH3 domain containing 1
chr20_+_58533471 0.34 ENST00000244047.5
ENST00000348616.4
cadherin 26
chr10_-_45474237 0.34 ENST00000448778.1
ENST00000298295.3
chromosome 10 open reading frame 10
chrY_+_15418467 0.33 ENST00000595988.1
Uncharacterized protein
chr5_+_138210919 0.33 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr11_-_71639446 0.33 ENST00000534704.1
Putative short transient receptor potential channel 2-like protein
chr2_-_132589601 0.31 ENST00000437330.1
AC103564.7
chr15_+_75640068 0.31 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
nei endonuclease VIII-like 1 (E. coli)
chr7_-_17500294 0.31 ENST00000439046.1
AC019117.2
chr3_+_69915385 0.30 ENST00000314589.5
microphthalmia-associated transcription factor
chr2_+_145780662 0.30 ENST00000423031.1
testis expressed 41 (non-protein coding)
chr8_-_95449155 0.30 ENST00000481490.2
fibrinogen silencer binding protein
chr4_+_71588372 0.30 ENST00000536664.1
RUN and FYVE domain containing 3
chr4_+_110749143 0.29 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr8_+_77318769 0.29 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr10_-_101825151 0.29 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr13_+_76334498 0.29 ENST00000534657.1
LIM domain 7
chr1_-_179834311 0.29 ENST00000553856.1
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr12_-_99548524 0.29 ENST00000549558.2
ENST00000550693.2
ENST00000549493.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr15_+_42696992 0.27 ENST00000561817.1
calpain 3, (p94)
chr1_+_168250194 0.27 ENST00000367821.3
T-box 19
chr2_-_207082748 0.26 ENST00000407325.2
ENST00000411719.1
G protein-coupled receptor 1
chr1_+_200638629 0.26 ENST00000568695.1
RP11-92G12.3
chr2_-_175711924 0.26 ENST00000444573.1
chimerin 1
chr11_-_8795787 0.26 ENST00000528196.1
ENST00000533681.1
suppression of tumorigenicity 5
chr10_+_115939008 0.25 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
tudor domain containing 1
chr5_+_75904918 0.25 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQ motif containing GTPase activating protein 2
chr10_-_14596140 0.25 ENST00000496330.1
family with sequence similarity 107, member B
chr20_+_20033158 0.25 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
chromosome 20 open reading frame 26
chr17_-_47786375 0.25 ENST00000511657.1
solute carrier family 35, member B1
chr19_-_36019123 0.24 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
suprabasin
chr4_+_159727272 0.24 ENST00000379346.3
folliculin interacting protein 2
chr19_-_36822551 0.24 ENST00000591372.1
long intergenic non-protein coding RNA 665
chr12_-_10321754 0.23 ENST00000539518.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr17_-_46691990 0.23 ENST00000576562.1
homeobox B8
chr21_-_16374688 0.23 ENST00000411932.1
nuclear receptor interacting protein 1
chr12_+_21525818 0.23 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
islet amyloid polypeptide
chrX_+_133941218 0.22 ENST00000370784.4
ENST00000370785.3
family with sequence similarity 122C
chr15_-_33360342 0.22 ENST00000558197.1
formin 1
chr8_+_9953061 0.22 ENST00000522907.1
ENST00000528246.1
methionine sulfoxide reductase A
chr3_-_196242233 0.22 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr1_+_89829610 0.22 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr4_-_170948361 0.22 ENST00000393702.3
microfibrillar-associated protein 3-like
chr11_+_34664014 0.22 ENST00000527935.1
ets homologous factor
chr3_-_120400960 0.22 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr2_-_175711978 0.22 ENST00000409089.2
chimerin 1
chr2_-_178128149 0.22 ENST00000423513.1
nuclear factor, erythroid 2-like 2
chrX_-_109590174 0.22 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr15_+_75639296 0.21 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
nei endonuclease VIII-like 1 (E. coli)
chr10_-_16563870 0.21 ENST00000298943.3
complement component 1, q subcomponent-like 3
chr12_+_79258444 0.21 ENST00000261205.4
synaptotagmin I
chr12_+_93963590 0.21 ENST00000340600.2
suppressor of cytokine signaling 2
chr4_-_186317034 0.20 ENST00000505916.1
LRP2 binding protein
chr14_-_31926623 0.20 ENST00000356180.4
D-tyrosyl-tRNA deacylase 2 (putative)
chr4_-_23891693 0.20 ENST00000264867.2
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr22_-_41864662 0.20 ENST00000216252.3
PHD finger protein 5A
chr12_+_32654965 0.20 ENST00000472289.1
FYVE, RhoGEF and PH domain containing 4
chr3_+_189507523 0.19 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr11_-_32452357 0.19 ENST00000379079.2
ENST00000530998.1
Wilms tumor 1
chr4_+_174089951 0.19 ENST00000512285.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr12_-_113841678 0.19 ENST00000552280.1
ENST00000257549.4
serine dehydratase
chr5_+_173473662 0.19 ENST00000519717.1
Neuron-specific protein family member 2
chr4_+_170581213 0.19 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr11_+_1891380 0.19 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr6_-_28220002 0.18 ENST00000377294.2
zinc finger with KRAB and SCAN domains 4
chrX_+_92929192 0.18 ENST00000332647.4
family with sequence similarity 133, member A
chr12_+_41221975 0.18 ENST00000552913.1
contactin 1
chr4_-_146859787 0.18 ENST00000508784.1
zinc finger protein 827
chr19_-_43099070 0.18 ENST00000244336.5
carcinoembryonic antigen-related cell adhesion molecule 8
chr1_+_62439037 0.18 ENST00000545929.1
InaD-like (Drosophila)
chr4_+_128554081 0.18 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr1_+_173991633 0.17 ENST00000424181.1
RP11-160H22.3
chr11_-_9088284 0.17 ENST00000531429.1
signal peptide, CUB domain, EGF-like 2
chr19_-_46706186 0.17 ENST00000601263.1
ENST00000598754.1
ENST00000594027.1
ENST00000598518.1
ENST00000599817.1
ENST00000595673.1
AC006262.5
chr1_+_203595689 0.17 ENST00000357681.5
ATPase, Ca++ transporting, plasma membrane 4
chr6_-_79944336 0.17 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr22_+_24105394 0.17 ENST00000305199.5
ENST00000382821.3
chromosome 22 open reading frame 15
chr8_+_9953214 0.17 ENST00000382490.5
methionine sulfoxide reductase A
chr2_+_145780767 0.17 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
testis expressed 41 (non-protein coding)
chr3_+_141105705 0.17 ENST00000513258.1
zinc finger and BTB domain containing 38
chr17_-_64188177 0.17 ENST00000535342.2
centrosomal protein 112kDa
chr1_-_146697185 0.17 ENST00000533174.1
ENST00000254090.4
flavin containing monooxygenase 5
chr12_-_8765446 0.17 ENST00000537228.1
ENST00000229335.6
activation-induced cytidine deaminase
chr20_-_14318248 0.16 ENST00000378053.3
ENST00000341420.4
fibronectin leucine rich transmembrane protein 3
chrX_+_102883887 0.16 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr2_+_135596180 0.16 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chrX_-_39956656 0.15 ENST00000397354.3
ENST00000378444.4
BCL6 corepressor
chr4_-_19458597 0.15 ENST00000505347.1
RP11-3J1.1
chr3_-_196159268 0.15 ENST00000381887.3
ENST00000535858.1
ENST00000428095.1
ENST00000296328.4
UBX domain protein 7
chr6_-_88001706 0.15 ENST00000369576.2
gap junction protein, beta 7, 25kDa
chr15_+_86087267 0.15 ENST00000558166.1
A kinase (PRKA) anchor protein 13
chr14_-_75083313 0.15 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr3_-_97690721 0.15 ENST00000506099.1
MYC induced nuclear antigen
chr11_+_74204883 0.15 ENST00000528481.1
polymerase (DNA-directed), delta 3, accessory subunit
chr3_+_186501979 0.15 ENST00000498746.1
eukaryotic translation initiation factor 4A2
chr8_+_74903580 0.14 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr8_-_67579418 0.14 ENST00000310421.4
valosin containing protein (p97)/p47 complex interacting protein 1
chr4_+_169633310 0.14 ENST00000510998.1
palladin, cytoskeletal associated protein
chr15_-_83240783 0.14 ENST00000568994.1
cytoplasmic polyadenylation element binding protein 1
chr21_+_43823983 0.14 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr4_+_159727222 0.14 ENST00000512986.1
folliculin interacting protein 2
chr12_-_81331460 0.14 ENST00000549417.1
lin-7 homolog A (C. elegans)
chr8_+_40010989 0.14 ENST00000315792.3
chromosome 8 open reading frame 4
chr11_-_108408895 0.14 ENST00000443411.1
ENST00000533052.1
exophilin 5
chr10_-_103603523 0.14 ENST00000370046.1
Kv channel interacting protein 2
chr17_+_45608430 0.14 ENST00000322157.4
aminopeptidase puromycin sensitive
chr22_+_41956767 0.14 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr19_-_40596828 0.14 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
zinc finger protein 780A
chr11_+_76745385 0.14 ENST00000533140.1
ENST00000354301.5
ENST00000528622.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr15_-_83240507 0.14 ENST00000564522.1
ENST00000398592.2
cytoplasmic polyadenylation element binding protein 1
chr10_-_22498950 0.13 ENST00000422359.2
endogenous Bornavirus-like nucleoprotein 1
chr19_-_52307357 0.13 ENST00000594900.1
formyl peptide receptor 1
chr16_+_19125252 0.13 ENST00000566735.1
ENST00000381440.3
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr3_+_57875711 0.13 ENST00000442599.2
sarcolemma associated protein
chr9_+_95909309 0.13 ENST00000366188.2
RP11-370F5.4
chr9_-_73483926 0.13 ENST00000396283.1
ENST00000361823.5
transient receptor potential cation channel, subfamily M, member 3
chr2_-_3584430 0.13 ENST00000438482.1
ENST00000422961.1
AC108488.4
chr4_+_114214125 0.13 ENST00000509550.1
ankyrin 2, neuronal
chr6_+_74405501 0.13 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr4_-_39367949 0.13 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
replication factor C (activator 1) 1, 145kDa
chr3_-_189839467 0.13 ENST00000426003.1
leprecan-like 1
chr15_+_79165222 0.13 ENST00000559930.1
mortality factor 4 like 1
chr5_-_59783882 0.13 ENST00000505507.2
ENST00000502484.2
phosphodiesterase 4D, cAMP-specific
chr1_+_39796810 0.13 ENST00000289893.4
microtubule-actin crosslinking factor 1
chr12_+_79258547 0.13 ENST00000457153.2
synaptotagmin I
chr15_+_75639951 0.13 ENST00000564784.1
ENST00000569035.1
nei endonuclease VIII-like 1 (E. coli)
chr5_+_96079240 0.13 ENST00000515663.1
calpastatin
chr5_+_180467259 0.13 ENST00000515271.1
butyrophilin-like 9
chr6_-_91296737 0.13 ENST00000369332.3
ENST00000369329.3
mitogen-activated protein kinase kinase kinase 7
chr17_-_49124230 0.13 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr17_-_62208169 0.12 ENST00000606895.1
endoplasmic reticulum to nucleus signaling 1
chr11_+_65122216 0.12 ENST00000309880.5
tigger transposable element derived 3
chr1_+_65775204 0.12 ENST00000371069.4
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_65018834 0.12 ENST00000506816.1
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr19_-_40724246 0.12 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr1_-_229478714 0.12 ENST00000284617.2
centriole, cilia and spindle-associated protein
chr1_+_28099683 0.12 ENST00000373943.4
syntaxin 12
chr1_+_61547405 0.12 ENST00000371189.4
nuclear factor I/A
chr15_+_59908633 0.12 ENST00000559626.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_59783540 0.12 ENST00000515734.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr12_+_41221794 0.12 ENST00000547849.1
contactin 1
chr7_+_114055052 0.12 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr8_+_54764346 0.12 ENST00000297313.3
ENST00000344277.6
regulator of G-protein signaling 20
chr4_-_146859623 0.12 ENST00000379448.4
ENST00000513320.1
zinc finger protein 827
chr12_+_510795 0.12 ENST00000412006.2
coiled-coil domain containing 77
chr15_-_83240553 0.12 ENST00000423133.2
ENST00000398591.2
cytoplasmic polyadenylation element binding protein 1
chr19_+_6373715 0.12 ENST00000599849.1
alkB, alkylation repair homolog 7 (E. coli)
chr13_-_86373536 0.12 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr6_-_4135693 0.12 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
enoyl-CoA delta isomerase 2
chr2_-_178128199 0.12 ENST00000449627.1
nuclear factor, erythroid 2-like 2
chr12_+_56661461 0.12 ENST00000546544.1
ENST00000553234.1
coenzyme Q10 homolog A (S. cerevisiae)
chr2_+_171036635 0.11 ENST00000484338.2
ENST00000334231.6
myosin IIIB
chr8_-_68255912 0.11 ENST00000262215.3
ENST00000519436.1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr9_+_74764278 0.11 ENST00000238018.4
ENST00000376989.3
guanine deaminase
chr19_-_9546177 0.11 ENST00000592292.1
ENST00000588221.1
zinc finger protein 266
chr6_+_45296048 0.11 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
runt-related transcription factor 2
chr4_-_88312301 0.11 ENST00000507286.1
hydroxysteroid (17-beta) dehydrogenase 11
chr6_+_31553978 0.11 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr20_-_45318230 0.11 ENST00000372114.3
TP53 regulating kinase
chr11_-_126810521 0.11 ENST00000530572.1
RP11-688I9.4
chr3_-_185826855 0.11 ENST00000306376.5
ets variant 5
chr1_+_167298281 0.11 ENST00000367862.5
POU class 2 homeobox 1
chrX_-_46187069 0.11 ENST00000446884.1
RP1-30G7.2
chr2_+_152214098 0.11 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr11_+_17298342 0.11 ENST00000530964.1
nucleobindin 2
chr8_+_132952112 0.11 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr15_+_75074915 0.11 ENST00000567123.1
ENST00000569462.1
c-src tyrosine kinase
chr4_-_103998439 0.11 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr4_-_76957214 0.11 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr2_+_187454749 0.11 ENST00000261023.3
ENST00000374907.3
integrin, alpha V
chr7_-_111202511 0.11 ENST00000452895.1
ENST00000452753.1
ENST00000331762.3
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr12_+_32259696 0.10 ENST00000551848.1
bicaudal D homolog 1 (Drosophila)
chr15_+_67841330 0.10 ENST00000354498.5
mitogen-activated protein kinase kinase 5
chr15_+_42787452 0.10 ENST00000249647.3
synaptosomal-associated protein, 23kDa
chr20_+_48909240 0.10 ENST00000371639.3
RP11-290F20.1
chr4_-_129209221 0.10 ENST00000512483.1
progesterone receptor membrane component 2
chr6_-_33864684 0.10 ENST00000506222.2
ENST00000533304.1
long intergenic non-protein coding RNA 1016
chr19_+_17416457 0.10 ENST00000252602.1
mitochondrial ribosomal protein L34
chr2_+_24150180 0.10 ENST00000404924.1
UBX domain protein 2A
chr11_+_111807863 0.10 ENST00000440460.2
DIX domain containing 1
chr3_+_9850199 0.10 ENST00000452597.1
tubulin tyrosine ligase-like family, member 3
chr10_-_21186144 0.10 ENST00000377119.1
nebulette
chr12_+_11905413 0.10 ENST00000545027.1
ets variant 6
chrX_+_123097014 0.10 ENST00000394478.1
stromal antigen 2
chr2_+_110656005 0.10 ENST00000437679.2
LIM and senescent cell antigen-like domains 3
chr5_-_13944652 0.10 ENST00000265104.4
dynein, axonemal, heavy chain 5

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:1904640 positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.2 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.4 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.2 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1902868 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:0042866 L-serine catabolic process(GO:0006565) pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0035566 negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.0 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.5 GO:0071294 cellular response to zinc ion(GO:0071294) cellular response to pH(GO:0071467)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:1904647 response to rotenone(GO:1904647)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.2 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis