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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OVOL1

Z-value: 0.20

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.5 ovo like transcriptional repressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OVOL1hg19_v2_chr11_+_65554493_65554546-0.374.7e-01Click!

Activity profile of OVOL1 motif

Sorted Z-values of OVOL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_67535647 0.38 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_21786179 0.08 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr14_+_29241910 0.07 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr17_-_7145475 0.07 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr11_-_130786333 0.06 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr11_-_75017734 0.06 ENST00000532525.1
ARRB1
arrestin, beta 1
chr4_+_39408470 0.05 ENST00000257408.4
KLB
klotho beta
chr16_-_67260691 0.04 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr5_+_140739537 0.04 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr15_+_75335604 0.04 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr19_-_46296011 0.03 ENST00000377735.3
ENST00000270223.6
DMWD
dystrophia myotonica, WD repeat containing
chr3_-_165555200 0.03 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr15_+_64386261 0.03 ENST00000560829.1
SNX1
sorting nexin 1
chr16_-_67260901 0.03 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr5_+_140261703 0.02 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr1_+_174846570 0.02 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr5_-_16509101 0.02 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chrX_-_117107542 0.01 ENST00000371878.1
KLHL13
kelch-like family member 13
chr7_-_148581360 0.01 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr11_+_123301012 0.00 ENST00000533341.1
AP000783.1
Uncharacterized protein
chrX_-_117107680 0.00 ENST00000447671.2
ENST00000262820.3
KLHL13
kelch-like family member 13

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.0 GO:0033265 choline binding(GO:0033265)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling