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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PAX6

Z-value: 0.75

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Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
PAX6
ENSG00000007372.16 paired box 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX6hg19_v2_chr11_-_31839488_318395150.921.0e-02Click!

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_79115503 1.10 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr12_+_113354341 1.10 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr3_+_172034218 0.93 ENST00000366261.2
AC092964.1
Uncharacterized protein
chr12_-_121476959 0.75 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr10_+_91092241 0.68 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr18_+_61420169 0.58 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_10007448 0.51 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr1_-_89458287 0.51 ENST00000370485.2
CCBL2
cysteine conjugate-beta lyase 2
chr2_-_202298268 0.47 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr1_+_218683438 0.42 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr3_+_108015382 0.40 ENST00000463019.3
ENST00000491820.1
ENST00000467562.1
ENST00000482430.1
ENST00000462629.1
HHLA2
HERV-H LTR-associating 2
chr1_-_86174065 0.39 ENST00000370574.3
ENST00000431532.2
ZNHIT6
zinc finger, HIT-type containing 6
chr8_-_95487331 0.38 ENST00000336148.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr14_+_24407940 0.37 ENST00000354854.1
DHRS4-AS1
DHRS4-AS1
chr2_-_176867534 0.37 ENST00000445472.1
KIAA1715
KIAA1715
chr1_-_89458415 0.36 ENST00000321792.5
ENST00000370491.3
RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr8_-_17103951 0.36 ENST00000520178.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr17_+_58499844 0.35 ENST00000269127.4
C17orf64
chromosome 17 open reading frame 64
chr4_+_130017268 0.34 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chrX_-_138914394 0.34 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr8_-_95487272 0.34 ENST00000297592.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr14_+_57671888 0.33 ENST00000391612.1
AL391152.1
AL391152.1
chr1_+_87380299 0.33 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr14_+_32476072 0.33 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr11_+_86667117 0.32 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr2_+_149402989 0.32 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_-_106449656 0.32 ENST00000372466.4
ENST00000421752.1
ENST00000372461.3
NUP62CL
nucleoporin 62kDa C-terminal like
chr18_+_61445007 0.32 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_196910477 0.31 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr1_+_223354486 0.31 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr8_+_16884740 0.30 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr8_+_121457642 0.30 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr1_+_163291732 0.29 ENST00000271452.3
NUF2
NUF2, NDC80 kinetochore complex component
chr2_+_172778952 0.29 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr21_-_35014027 0.28 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr10_-_27389320 0.27 ENST00000436985.2
ANKRD26
ankyrin repeat domain 26
chr14_+_56127960 0.27 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr12_+_83080659 0.27 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr4_-_129491686 0.26 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr15_-_56757329 0.26 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr3_+_151531810 0.26 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr1_+_207925391 0.26 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
CD46
CD46 molecule, complement regulatory protein
chr8_-_121457332 0.25 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr18_-_37380230 0.25 ENST00000591629.1
LINC00669
long intergenic non-protein coding RNA 669
chr2_-_70520539 0.25 ENST00000482975.2
ENST00000438261.1
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr21_-_18985230 0.25 ENST00000457956.1
ENST00000348354.6
BTG3
BTG family, member 3
chr7_+_112120908 0.25 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1
leucine-rich single-pass membrane protein 1
chr17_+_57297807 0.24 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr2_+_114195268 0.24 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr2_-_162931052 0.23 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr6_-_64029879 0.23 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr5_+_118668846 0.23 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_+_151531859 0.23 ENST00000488869.1
AADAC
arylacetamide deacetylase
chr17_-_39023462 0.22 ENST00000251643.4
KRT12
keratin 12
chr13_+_25875785 0.22 ENST00000381747.3
NUPL1
nucleoporin like 1
chr16_-_79804394 0.22 ENST00000567993.1
RP11-345M22.2
RP11-345M22.2
chr2_+_196521845 0.22 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_+_13628921 0.21 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr12_-_70093162 0.21 ENST00000551160.1
BEST3
bestrophin 3
chr5_-_98262240 0.21 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr16_+_85391069 0.21 ENST00000568080.1
RP11-680G10.1
Uncharacterized protein
chr12_+_113416340 0.21 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr5_+_93954039 0.21 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr6_-_26043885 0.21 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr5_+_94982558 0.21 ENST00000311364.4
ENST00000458310.1
RFESD
Rieske (Fe-S) domain containing
chr2_+_145780725 0.20 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr11_-_58343319 0.20 ENST00000395074.2
LPXN
leupaxin
chr6_+_88299833 0.20 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr6_-_117923520 0.20 ENST00000368498.2
GOPC
golgi-associated PDZ and coiled-coil motif containing
chr8_+_59323823 0.20 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr12_+_69080734 0.20 ENST00000378905.2
NUP107
nucleoporin 107kDa
chr10_+_13628933 0.20 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr5_+_119799927 0.19 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr17_-_58499766 0.19 ENST00000588898.1
USP32
ubiquitin specific peptidase 32
chr2_+_101223490 0.19 ENST00000414647.1
ENST00000424342.1
AC068538.4
AC068538.4
chr1_-_43282906 0.19 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr16_-_71264558 0.18 ENST00000448089.2
ENST00000393550.2
ENST00000448691.1
ENST00000393567.2
ENST00000321489.5
ENST00000539973.1
ENST00000288168.10
ENST00000545267.1
ENST00000541601.1
ENST00000538248.1
HYDIN
HYDIN, axonemal central pair apparatus protein
chr15_+_63889822 0.18 ENST00000560325.1
FBXL22
F-box and leucine-rich repeat protein 22
chr3_-_196910721 0.18 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_-_74776586 0.18 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr1_-_110933663 0.18 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr2_+_202098203 0.18 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr1_-_87380002 0.18 ENST00000331835.5
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr10_-_27389392 0.17 ENST00000376087.4
ANKRD26
ankyrin repeat domain 26
chr19_+_42037433 0.16 ENST00000599316.1
ENST00000599770.1
AC006129.1
AC006129.1
chr13_+_25875662 0.16 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr8_-_121457608 0.16 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr7_-_152373216 0.16 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr4_-_65275162 0.16 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr12_-_69080590 0.16 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr11_-_11374904 0.16 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr1_-_110933611 0.16 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr16_-_47493041 0.16 ENST00000565940.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr6_-_88299678 0.16 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr11_-_28129656 0.15 ENST00000263181.6
KIF18A
kinesin family member 18A
chr11_-_117747434 0.15 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr3_-_195310802 0.15 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr1_+_114522049 0.15 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr3_-_142297668 0.15 ENST00000350721.4
ENST00000383101.3
ATR
ataxia telangiectasia and Rad3 related
chr10_-_118765081 0.15 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr2_+_228190066 0.14 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
MFF
mitochondrial fission factor
chr14_+_32547434 0.14 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr4_+_70894130 0.14 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr2_+_145780739 0.14 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr2_-_29093132 0.14 ENST00000306108.5
TRMT61B
tRNA methyltransferase 61 homolog B (S. cerevisiae)
chr1_-_87379785 0.14 ENST00000401030.3
ENST00000370554.1
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr4_-_69215467 0.14 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr1_-_43282945 0.14 ENST00000537227.1
CCDC23
coiled-coil domain containing 23
chr2_-_136743169 0.14 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr2_+_192110199 0.14 ENST00000304164.4
MYO1B
myosin IB
chr19_-_37701386 0.13 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B
zinc finger protein 585B
chr17_-_58096336 0.13 ENST00000587125.1
ENST00000407042.3
TBC1D3P1-DHX40P1
TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
chr3_-_101232019 0.13 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr11_+_74811578 0.13 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr2_+_238877424 0.13 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr1_-_165738072 0.13 ENST00000481278.1
TMCO1
transmembrane and coiled-coil domains 1
chr10_-_17243579 0.13 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr12_-_56352368 0.13 ENST00000549404.1
PMEL
premelanosome protein
chr6_-_52859046 0.13 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr1_+_104068562 0.13 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr11_-_61849656 0.13 ENST00000524942.1
RP11-810P12.5
RP11-810P12.5
chr5_-_68339648 0.13 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr17_-_8661860 0.13 ENST00000328794.6
SPDYE4
speedy/RINGO cell cycle regulator family member E4
chr12_-_85306562 0.12 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr2_+_196521903 0.12 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr5_-_58882219 0.12 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_134373732 0.12 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr10_-_118764862 0.12 ENST00000260777.10
KIAA1598
KIAA1598
chr3_-_171489085 0.12 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr8_-_19614810 0.12 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr16_-_15982440 0.12 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
FOPNL
FGFR1OP N-terminal like
chr2_+_196521458 0.12 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr22_+_39745930 0.11 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chr11_-_10828892 0.11 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr6_-_85474219 0.11 ENST00000369663.5
TBX18
T-box 18
chr18_-_21242774 0.11 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr6_+_125475335 0.11 ENST00000532429.1
ENST00000534199.1
TPD52L1
tumor protein D52-like 1
chr4_+_40751914 0.11 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chr8_+_142402089 0.11 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr2_+_192109911 0.11 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr11_-_102401469 0.10 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr17_+_43224684 0.10 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr6_-_26033796 0.10 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr6_+_125474992 0.10 ENST00000528193.1
TPD52L1
tumor protein D52-like 1
chr18_+_18822185 0.10 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
GREB1L
growth regulation by estrogen in breast cancer-like
chr1_-_165738085 0.09 ENST00000464650.1
ENST00000392129.6
TMCO1
transmembrane and coiled-coil domains 1
chr7_+_90012986 0.09 ENST00000416322.1
CLDN12
claudin 12
chr7_-_97501706 0.09 ENST00000455086.1
ENST00000453600.1
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr8_-_62602327 0.09 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr17_-_39216344 0.09 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr16_-_51185172 0.09 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr12_+_27175476 0.09 ENST00000546323.1
ENST00000282892.3
MED21
mediator complex subunit 21
chr12_-_122884553 0.09 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr12_+_83080724 0.09 ENST00000548305.1
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chrX_-_64196351 0.09 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr11_-_117748138 0.09 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr1_+_73771844 0.08 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr1_+_203765437 0.08 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr8_+_21882244 0.08 ENST00000289820.6
ENST00000381530.5
NPM2
nucleophosmin/nucleoplasmin 2
chrX_-_64196376 0.08 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr22_-_30968839 0.08 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr15_+_52155001 0.08 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr16_-_51185149 0.08 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chrX_-_130423386 0.08 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr2_-_175869936 0.08 ENST00000409900.3
CHN1
chimerin 1
chr11_-_117747607 0.08 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr2_+_228189941 0.08 ENST00000353339.3
ENST00000354503.6
ENST00000530359.1
ENST00000531278.1
ENST00000409565.1
ENST00000452930.1
ENST00000409616.1
ENST00000337110.7
ENST00000525195.1
ENST00000534203.1
ENST00000524634.1
ENST00000349901.7
MFF
mitochondrial fission factor
chr10_+_35894338 0.08 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr12_-_47473425 0.07 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr2_-_86116020 0.07 ENST00000525834.2
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_145780767 0.07 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr15_-_65282274 0.07 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr12_-_45270077 0.07 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr1_-_211666259 0.07 ENST00000367002.4
RD3
retinal degeneration 3
chr12_-_45270151 0.07 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr1_-_144932014 0.07 ENST00000529945.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr9_-_16870704 0.07 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr19_-_36019123 0.07 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr12_-_53575120 0.07 ENST00000542115.1
CSAD
cysteine sulfinic acid decarboxylase
chr18_+_13611431 0.07 ENST00000587757.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr7_-_87342564 0.07 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_-_40680578 0.07 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_99870744 0.07 ENST00000409238.1
ENST00000423800.1
LYG2
lysozyme G-like 2
chr19_+_50936142 0.07 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr4_-_88141615 0.07 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
KLHL8
kelch-like family member 8
chr10_+_35415851 0.06 ENST00000374726.3
CREM
cAMP responsive element modulator
chr6_+_170151708 0.06 ENST00000592367.1
ENST00000590711.1
ENST00000366772.2
ENST00000592745.1
ENST00000392095.4
ENST00000366773.3
ENST00000586341.1
ENST00000418781.3
ENST00000588437.1
ERMARD
ER membrane-associated RNA degradation
chr11_-_18813353 0.06 ENST00000358540.2
ENST00000396171.4
ENST00000396167.2
PTPN5
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr21_-_35884573 0.06 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr8_-_21771182 0.06 ENST00000523932.1
ENST00000544659.1
DOK2
docking protein 2, 56kDa
chr10_+_116524547 0.06 ENST00000436932.1
RP11-106M7.1
RP11-106M7.1
chr22_-_30968813 0.06 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr2_-_165812028 0.06 ENST00000303735.4
SLC38A11
solute carrier family 38, member 11
chrX_-_130423240 0.06 ENST00000370910.1
ENST00000370901.4
IGSF1
immunoglobulin superfamily, member 1
chr8_+_95558771 0.06 ENST00000391679.1
AC023632.1
HCG2009141; PRO2397; Uncharacterized protein
chr9_-_140142181 0.05 ENST00000484720.1
FAM166A
family with sequence similarity 166, member A
chr8_+_18067602 0.05 ENST00000307719.4
ENST00000545197.1
ENST00000539092.1
ENST00000541942.1
ENST00000518029.1
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr5_-_159546396 0.05 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr3_+_51663407 0.05 ENST00000432863.1
ENST00000296477.3
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr8_-_13372253 0.05 ENST00000316609.5
DLC1
deleted in liver cancer 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1 0.4 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.2 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.1 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.5 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.9 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.2 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.1 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.0 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0075341 host cell PML body(GO:0075341)
0.1 0.4 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.5 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.2 2.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters