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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX1

Z-value: 0.98

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
PBX1
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164600184_164600218-0.815.0e-02Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_38821373 1.21 ENST00000394052.3
KRT222
keratin 222
chr7_-_92747269 1.14 ENST00000446617.1
ENST00000379958.2
SAMD9
sterile alpha motif domain containing 9
chr3_-_129375556 0.93 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr18_+_44526786 0.85 ENST00000245121.5
ENST00000356157.7
KATNAL2
katanin p60 subunit A-like 2
chrM_+_4431 0.83 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr6_+_27114861 0.83 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr10_+_63422695 0.76 ENST00000330194.2
ENST00000389639.3
C10orf107
chromosome 10 open reading frame 107
chrM_+_14741 0.69 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr12_+_21679220 0.64 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr16_-_63651939 0.56 ENST00000563855.1
ENST00000568932.1
ENST00000564290.1
RP11-368L12.1
RP11-368L12.1
chr22_+_50981079 0.52 ENST00000609268.1
CTA-384D8.34
CTA-384D8.34
chr13_-_48612067 0.50 ENST00000543413.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr5_+_65440032 0.48 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr5_+_162864575 0.47 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chrM_-_14670 0.45 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr10_-_5638048 0.45 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr7_+_7196565 0.41 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_238108575 0.41 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr8_-_42360015 0.40 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chrM_+_9207 0.39 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr11_+_95523621 0.38 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr4_+_26324474 0.38 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr17_+_58018269 0.38 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr4_+_83956237 0.37 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr12_+_21654714 0.37 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr11_+_44117219 0.36 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr14_+_38033252 0.35 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr10_-_18948208 0.35 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr9_-_88356789 0.35 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr4_+_83956312 0.35 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr7_+_120629653 0.35 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr14_-_64846033 0.34 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr3_-_149510553 0.34 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr21_-_35014027 0.33 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr7_+_23637763 0.33 ENST00000410069.1
CCDC126
coiled-coil domain containing 126
chr17_-_26694979 0.32 ENST00000438614.1
VTN
vitronectin
chr16_+_50059182 0.32 ENST00000562576.1
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr5_-_86708670 0.32 ENST00000504878.1
CCNH
cyclin H
chr13_+_97928395 0.31 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr12_+_41136144 0.30 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr12_+_79258444 0.30 ENST00000261205.4
SYT1
synaptotagmin I
chr9_+_106856831 0.29 ENST00000303219.8
ENST00000374787.3
SMC2
structural maintenance of chromosomes 2
chr2_+_201997595 0.29 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_-_133702761 0.28 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
CDKL3
cyclin-dependent kinase-like 3
chr2_+_12857015 0.28 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr6_+_27775899 0.27 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr12_+_20968608 0.27 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr19_+_33072373 0.27 ENST00000586035.1
PDCD5
programmed cell death 5
chr8_-_6115044 0.27 ENST00000519555.1
RP11-124B13.1
RP11-124B13.1
chr11_-_34937858 0.26 ENST00000278359.5
APIP
APAF1 interacting protein
chr1_+_104159999 0.26 ENST00000414303.2
ENST00000423678.1
AMY2A
amylase, alpha 2A (pancreatic)
chr18_+_29171689 0.26 ENST00000237014.3
TTR
transthyretin
chr4_-_105416039 0.26 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr13_+_95254085 0.25 ENST00000376958.4
GPR180
G protein-coupled receptor 180
chr6_+_99282570 0.25 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr8_-_108510224 0.25 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr11_+_95523823 0.25 ENST00000538658.1
CEP57
centrosomal protein 57kDa
chr10_-_18948156 0.25 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1
ARL5B antisense RNA 1
chr3_+_150264458 0.25 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr5_-_86708833 0.25 ENST00000256897.4
CCNH
cyclin H
chr11_-_2162162 0.24 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_-_120498357 0.24 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr13_-_22033392 0.24 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr22_-_29137771 0.24 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr10_+_5238793 0.23 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr9_-_6015607 0.23 ENST00000259569.5
RANBP6
RAN binding protein 6
chr14_-_36789783 0.23 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr5_-_132073111 0.23 ENST00000403231.1
KIF3A
kinesin family member 3A
chr12_-_76478686 0.22 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr14_+_50065376 0.22 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr6_-_26032288 0.22 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr4_-_70626430 0.21 ENST00000310613.3
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr14_+_88851874 0.21 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr6_-_7313381 0.21 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1
signal sequence receptor, alpha
chr3_+_150264555 0.21 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr19_-_58400148 0.21 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr11_-_34938039 0.21 ENST00000395787.3
APIP
APAF1 interacting protein
chrX_+_92929192 0.20 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chr4_-_70080449 0.20 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chrM_+_10053 0.20 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr4_+_69962185 0.20 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_+_201997492 0.20 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_21654479 0.19 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RECQL
RecQ protein-like (DNA helicase Q1-like)
chrX_+_119737806 0.19 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr2_+_201242715 0.19 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr2_+_234104079 0.19 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr15_+_36871983 0.19 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr8_-_95487331 0.19 ENST00000336148.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr12_-_102455846 0.19 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr3_+_186743261 0.19 ENST00000423451.1
ENST00000446170.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_+_79258547 0.19 ENST00000457153.2
SYT1
synaptotagmin I
chr5_+_68513622 0.18 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chrX_+_95939638 0.18 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr17_+_43239191 0.18 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr18_+_20494078 0.18 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr6_-_26199471 0.17 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr3_+_179280668 0.17 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr3_-_143567262 0.17 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr12_-_54653313 0.17 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr18_-_59854203 0.17 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
PIGN
phosphatidylinositol glycan anchor biosynthesis, class N
chrX_+_1734051 0.17 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr5_-_43313574 0.17 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr22_+_29138013 0.16 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr18_+_44526744 0.16 ENST00000585469.1
KATNAL2
katanin p60 subunit A-like 2
chr11_+_34938119 0.16 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr4_-_140005443 0.15 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr1_-_54405773 0.15 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr3_-_120461378 0.15 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr19_+_35417939 0.14 ENST00000601142.1
ENST00000426813.2
ZNF30
zinc finger protein 30
chr15_-_54025300 0.13 ENST00000559418.1
WDR72
WD repeat domain 72
chr14_-_64971893 0.13 ENST00000555220.1
ZBTB25
zinc finger and BTB domain containing 25
chr4_+_69962212 0.13 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr11_+_61717336 0.13 ENST00000378042.3
BEST1
bestrophin 1
chrX_+_95939711 0.13 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr11_+_47279155 0.13 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr16_+_19222479 0.13 ENST00000568433.1
SYT17
synaptotagmin XVII
chr5_-_179045199 0.13 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr14_+_104182105 0.13 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr14_+_104182061 0.13 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr3_-_129158676 0.13 ENST00000393278.2
MBD4
methyl-CpG binding domain protein 4
chr12_-_15104040 0.12 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_61717279 0.12 ENST00000378043.4
BEST1
bestrophin 1
chr7_-_27142290 0.12 ENST00000222718.5
HOXA2
homeobox A2
chr16_-_49890016 0.12 ENST00000563137.2
ZNF423
zinc finger protein 423
chr3_-_129158850 0.12 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
MBD4
methyl-CpG binding domain protein 4
chr2_+_201997676 0.12 ENST00000462763.1
ENST00000479953.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr6_+_83777374 0.12 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr4_-_48683188 0.12 ENST00000505759.1
FRYL
FRY-like
chr11_+_114166536 0.12 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr11_+_122753391 0.12 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr13_+_98086445 0.11 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr14_+_50065459 0.11 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr5_+_177433406 0.11 ENST00000504530.1
FAM153C
family with sequence similarity 153, member C
chr7_-_38969150 0.11 ENST00000418457.2
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr7_-_112430647 0.11 ENST00000312814.6
TMEM168
transmembrane protein 168
chr5_+_151151504 0.11 ENST00000356245.3
ENST00000507878.2
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr10_+_60028818 0.11 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr14_-_55907334 0.11 ENST00000247219.5
TBPL2
TATA box binding protein like 2
chr8_+_99076509 0.11 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr12_+_81471816 0.11 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr2_+_12857043 0.10 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr2_-_158182105 0.10 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr19_-_3801789 0.10 ENST00000590849.1
ENST00000395045.2
MATK
megakaryocyte-associated tyrosine kinase
chr7_+_134331550 0.10 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr12_-_57472522 0.10 ENST00000379391.3
ENST00000300128.4
TMEM194A
transmembrane protein 194A
chr4_-_69536346 0.10 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr19_+_5681153 0.10 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr7_+_77325738 0.10 ENST00000334955.8
RSBN1L
round spermatid basic protein 1-like
chr14_+_24584372 0.10 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11
DDB1 and CUL4 associated factor 11
chr18_-_48346415 0.10 ENST00000431965.2
ENST00000436348.2
MRO
maestro
chr8_-_101965559 0.10 ENST00000353245.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr21_-_16125773 0.10 ENST00000454128.2
AF127936.3
AF127936.3
chr3_-_161090660 0.10 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr5_+_151151471 0.10 ENST00000394123.3
ENST00000543466.1
G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_20646824 0.10 ENST00000272233.4
RHOB
ras homolog family member B
chr12_-_56848426 0.10 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr10_+_69865866 0.10 ENST00000354393.2
MYPN
myopalladin
chr9_+_113431029 0.10 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK
muscle, skeletal, receptor tyrosine kinase
chr4_-_111536534 0.10 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2
RP11-380D23.2
chr17_-_26695013 0.10 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr1_+_104293028 0.09 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr8_-_101965146 0.09 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_-_42825983 0.09 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr6_-_26199499 0.09 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr12_-_102455902 0.09 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr21_+_27543175 0.08 ENST00000608591.1
ENST00000609365.1
AP000230.1
AP000230.1
chr4_+_118349545 0.08 ENST00000422145.3
ENST00000437514.1
AC092661.1
AC092661.1
chr12_+_56401268 0.08 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr3_-_72150076 0.08 ENST00000488545.1
ENST00000608654.1
LINC00877
long intergenic non-protein coding RNA 877
chr6_-_84417633 0.08 ENST00000521931.1
SNAP91
synaptosomal-associated protein, 91kDa
chr11_+_68228186 0.08 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3
protein phosphatase 6, regulatory subunit 3
chr3_+_111451321 0.08 ENST00000393923.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr6_-_32784687 0.08 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr12_+_133657461 0.08 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr15_+_81591757 0.07 ENST00000558332.1
IL16
interleukin 16
chr2_+_264913 0.07 ENST00000439645.2
ENST00000405233.1
ACP1
acid phosphatase 1, soluble
chr3_-_120461353 0.07 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr12_-_96389702 0.07 ENST00000552509.1
HAL
histidine ammonia-lyase
chr10_-_105845674 0.07 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr8_+_133909919 0.07 ENST00000518505.1
TG
thyroglobulin
chr8_-_95487272 0.07 ENST00000297592.5
RAD54B
RAD54 homolog B (S. cerevisiae)
chr2_+_234600253 0.07 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_167040693 0.06 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_69619823 0.06 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr2_-_154335300 0.06 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr20_+_48909240 0.06 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chrX_+_140084756 0.06 ENST00000449283.1
SPANXB2
SPANX family, member B2
chr8_-_116681221 0.06 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr22_+_31795509 0.06 ENST00000331457.4
DRG1
developmentally regulated GTP binding protein 1
chr2_-_27886676 0.06 ENST00000337768.5
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr2_+_44396000 0.06 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr21_+_27011899 0.06 ENST00000425221.2
JAM2
junctional adhesion molecule 2
chr16_+_50059125 0.06 ENST00000427478.2
CNEP1R1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr7_-_107883678 0.06 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr1_-_115323245 0.05 ENST00000060969.5
ENST00000369528.5
SIKE1
suppressor of IKBKE 1
chr12_+_123944070 0.05 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr4_-_38784592 0.05 ENST00000502321.1
TLR10
toll-like receptor 10
chr15_-_60695071 0.05 ENST00000557904.1
ANXA2
annexin A2
chr13_-_24895566 0.05 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr6_-_84418432 0.05 ENST00000519825.1
ENST00000523484.2
SNAP91
synaptosomal-associated protein, 91kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.5 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.0 GO:0071400 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines