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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM1

Z-value: 1.50

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106535455_1065356370.796.3e-02Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_131746575 1.55 ENST00000337752.2
ENST00000378947.3
ENST00000407797.1
C5orf56
chromosome 5 open reading frame 56
chr16_-_67970990 1.31 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr10_-_81203972 1.28 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_-_36779411 1.18 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr7_-_105332084 1.13 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr21_+_17909594 1.09 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_86650077 1.02 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_121655850 0.83 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr12_+_43086018 0.80 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr5_-_159766528 0.77 ENST00000505287.2
CCNJL
cyclin J-like
chr15_+_85144217 0.75 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr2_+_239756671 0.74 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr1_+_207262881 0.73 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr7_+_134832808 0.72 ENST00000275767.3
TMEM140
transmembrane protein 140
chrX_-_63005405 0.72 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_+_94656297 0.69 ENST00000545312.1
PLXNC1
plexin C1
chr3_+_8543393 0.69 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr4_+_186990298 0.65 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr8_+_39770803 0.64 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr7_-_86848933 0.64 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr3_-_64431146 0.62 ENST00000569824.1
ENST00000485770.1
PRICKLE2
RP11-14D22.2
prickle homolog 2 (Drosophila)
RP11-14D22.2
chr13_-_95364389 0.61 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr1_-_8483723 0.60 ENST00000476556.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr7_-_3083472 0.60 ENST00000356408.3
CARD11
caspase recruitment domain family, member 11
chr17_+_46908350 0.59 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr12_-_71003568 0.58 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_+_69915363 0.57 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr7_-_111424462 0.56 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr22_-_31688431 0.56 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr8_-_9009079 0.56 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr20_+_388679 0.56 ENST00000356286.5
ENST00000475269.1
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_100140331 0.54 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr20_+_388791 0.54 ENST00000441733.1
ENST00000353660.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr20_+_388935 0.54 ENST00000382181.2
ENST00000400247.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr8_+_9009202 0.54 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr17_+_7211656 0.53 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr6_+_106535455 0.53 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr6_-_33282024 0.53 ENST00000475304.1
ENST00000489157.1
TAPBP
TAP binding protein (tapasin)
chr3_+_8543561 0.52 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr16_-_88851618 0.51 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr10_-_44880491 0.50 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
CXCL12
chemokine (C-X-C motif) ligand 12
chr14_-_69263043 0.50 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_+_212782012 0.50 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr3_+_8543533 0.48 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr14_-_69262947 0.47 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr14_-_69262789 0.47 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr5_-_94417186 0.46 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr12_-_118498958 0.46 ENST00000315436.3
WSB2
WD repeat and SOCS box containing 2
chr22_-_31688381 0.45 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr15_-_72565340 0.45 ENST00000568360.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_-_161014731 0.43 ENST00000368020.1
USF1
upstream transcription factor 1
chr2_+_145780662 0.42 ENST00000423031.1
TEX41
testis expressed 41 (non-protein coding)
chr6_-_33282163 0.42 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr22_+_39436862 0.41 ENST00000381565.2
ENST00000452957.2
APOBEC3F
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr5_-_66942617 0.41 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr11_-_47736896 0.41 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr12_-_118498911 0.40 ENST00000544233.1
WSB2
WD repeat and SOCS box containing 2
chr5_-_94417339 0.40 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_+_3466248 0.39 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr19_+_34287751 0.38 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr5_-_94417314 0.38 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr11_+_64323156 0.38 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_-_33281979 0.38 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr22_-_36635225 0.38 ENST00000529194.1
APOL2
apolipoprotein L, 2
chr12_+_25205446 0.38 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr3_-_114343039 0.36 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_111558135 0.36 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr16_+_31085714 0.36 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646
zinc finger protein 646
chr4_+_183065793 0.35 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chrX_+_123095860 0.35 ENST00000428941.1
STAG2
stromal antigen 2
chr17_+_6659354 0.35 ENST00000574907.1
XAF1
XIAP associated factor 1
chr8_+_77593448 0.35 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr8_+_77593474 0.35 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr8_+_97506033 0.35 ENST00000518385.1
SDC2
syndecan 2
chr20_-_52612705 0.34 ENST00000434986.2
BCAS1
breast carcinoma amplified sequence 1
chr4_-_48782259 0.34 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr8_-_79717163 0.34 ENST00000520269.1
IL7
interleukin 7
chr4_+_146403912 0.33 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr11_-_796197 0.33 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_-_145275828 0.33 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr8_-_29120580 0.33 ENST00000524189.1
KIF13B
kinesin family member 13B
chr1_+_151372010 0.32 ENST00000290541.6
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr4_-_153303658 0.32 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_-_111424506 0.32 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr15_+_75491213 0.32 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr6_-_10412600 0.32 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr19_+_24009879 0.31 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr6_+_31540056 0.31 ENST00000418386.2
LTA
lymphotoxin alpha
chr13_+_24144796 0.31 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr17_-_43339474 0.31 ENST00000331780.4
SPATA32
spermatogenesis associated 32
chr14_-_69262916 0.31 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr16_+_84801852 0.30 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr16_+_20685815 0.30 ENST00000561584.1
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr1_+_17906970 0.29 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr5_+_92919043 0.29 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr10_+_122610853 0.29 ENST00000604585.1
WDR11
WD repeat domain 11
chr3_+_69915385 0.28 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr12_+_94542459 0.28 ENST00000258526.4
PLXNC1
plexin C1
chr6_-_28220002 0.27 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr8_-_142012169 0.27 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr14_-_23479331 0.26 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr10_-_82049424 0.26 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr7_-_122526499 0.25 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chrX_-_154563889 0.25 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr13_-_33924755 0.25 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_+_142558078 0.24 ENST00000529613.1
IL15
interleukin 15
chr11_+_64323428 0.24 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chrX_+_123095890 0.24 ENST00000435215.1
STAG2
stromal antigen 2
chr15_-_37393406 0.24 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr22_+_41697520 0.24 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr2_-_145275228 0.23 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr3_+_185046676 0.23 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr12_+_51318513 0.23 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr16_+_50775971 0.23 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_29527702 0.23 ENST00000377050.4
UBD
ubiquitin D
chr16_-_3930724 0.23 ENST00000262367.5
CREBBP
CREB binding protein
chr12_-_57504975 0.23 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr3_+_47422485 0.23 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23
protein tyrosine phosphatase, non-receptor type 23
chr6_-_138820624 0.22 ENST00000343505.5
NHSL1
NHS-like 1
chrX_-_118826784 0.22 ENST00000394616.4
SEPT6
septin 6
chr5_+_86563636 0.22 ENST00000274376.6
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr1_-_153919128 0.22 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr2_+_179184955 0.21 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr8_-_56986768 0.21 ENST00000523936.1
RPS20
ribosomal protein S20
chr4_-_146859787 0.21 ENST00000508784.1
ZNF827
zinc finger protein 827
chr6_-_41909191 0.20 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr8_-_116681221 0.20 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr12_-_120189900 0.20 ENST00000546026.1
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr11_+_71709938 0.20 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr11_+_28129795 0.20 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15
methyltransferase like 15
chr20_+_30946106 0.19 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr9_-_69229650 0.19 ENST00000416428.1
CBWD6
COBW domain containing 6
chr1_-_221915418 0.19 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr3_+_51977294 0.19 ENST00000498510.1
PARP3
poly (ADP-ribose) polymerase family, member 3
chr6_-_44400720 0.19 ENST00000595057.1
AL133262.1
AL133262.1
chr1_-_151735937 0.19 ENST00000368829.3
ENST00000368830.3
MRPL9
mitochondrial ribosomal protein L9
chr15_-_37392086 0.18 ENST00000561208.1
MEIS2
Meis homeobox 2
chr22_-_36635598 0.18 ENST00000454728.1
APOL2
apolipoprotein L, 2
chr1_+_110453462 0.18 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr3_+_107241882 0.18 ENST00000416476.2
BBX
bobby sox homolog (Drosophila)
chr8_-_29120604 0.18 ENST00000521515.1
KIF13B
kinesin family member 13B
chr1_+_28099700 0.18 ENST00000440806.2
STX12
syntaxin 12
chr17_-_26695013 0.17 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr4_-_100242549 0.17 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_+_93861993 0.17 ENST00000227638.3
ENST00000436171.2
PANX1
pannexin 1
chr11_-_72432950 0.17 ENST00000426523.1
ENST00000429686.1
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_+_95401877 0.16 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr9_+_137533615 0.16 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr11_+_64008443 0.16 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chrX_-_118827113 0.16 ENST00000394617.2
SEPT6
septin 6
chr12_-_86650045 0.15 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_+_53659746 0.15 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr9_+_84304628 0.15 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr3_+_119013185 0.15 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr6_-_112575912 0.15 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr22_-_36556821 0.15 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr1_+_11832179 0.15 ENST00000312793.5
C1orf167
chromosome 1 open reading frame 167
chr6_-_137113604 0.15 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr19_+_34287174 0.15 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr13_+_24144509 0.14 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr13_+_108921977 0.14 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr12_+_51317788 0.14 ENST00000550502.1
METTL7A
methyltransferase like 7A
chr6_-_99797522 0.14 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr1_-_44497024 0.14 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_140430979 0.13 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr1_+_2985760 0.13 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chrX_-_106362013 0.12 ENST00000372487.1
ENST00000372479.3
ENST00000203616.8
RBM41
RNA binding motif protein 41
chr2_+_166150541 0.12 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr6_-_112575838 0.12 ENST00000455073.1
LAMA4
laminin, alpha 4
chr11_+_64323098 0.12 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr21_+_43933946 0.11 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr8_-_116680833 0.11 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr9_+_133454943 0.11 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr1_+_2985726 0.11 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr17_+_74372662 0.11 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr1_+_110453203 0.11 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr5_+_73109339 0.11 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr6_-_10413112 0.11 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr22_-_36635563 0.11 ENST00000451256.2
APOL2
apolipoprotein L, 2
chrX_+_114874727 0.11 ENST00000543070.1
PLS3
plastin 3
chr8_+_134203303 0.11 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr22_-_36635684 0.10 ENST00000358502.5
APOL2
apolipoprotein L, 2
chr4_+_152020715 0.10 ENST00000274065.4
RPS3A
ribosomal protein S3A
chr5_+_76506706 0.10 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr5_-_59481406 0.10 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_140544386 0.10 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr10_+_18429606 0.10 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr19_+_49977818 0.09 ENST00000594009.1
ENST00000595510.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr1_+_164600184 0.09 ENST00000482110.1
PBX1
pre-B-cell leukemia homeobox 1
chrX_-_133930285 0.09 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr11_+_64008525 0.09 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr18_+_18943554 0.09 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr19_+_17186577 0.09 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr5_-_64064508 0.09 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr11_+_128563652 0.08 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_-_116681686 0.08 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr17_+_3379284 0.08 ENST00000263080.2
ASPA
aspartoacylase
chr1_+_156737292 0.07 ENST00000271526.4
ENST00000353233.3
PRCC
papillary renal cell carcinoma (translocation-associated)
chr8_-_23540402 0.07 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr12_+_6561190 0.07 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.3 1.7 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 1.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.9 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 0.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 0.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 1.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.7 GO:0034344 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.7 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:0003409 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.7 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 1.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.7 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.6 GO:0098792 xenophagy(GO:0098792)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.0 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:2000836 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.3 GO:0042825 TAP complex(GO:0042825)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.4 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 0.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.8 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation